저강도 자전거에르고미터 운동프로그램이 혈장지질 농도에 미치는 영향

성봉주,남형천,김상우 한국학교체육학회 2001 한국학교 체육학회지 Vol.11 No.1

본 연구의 목적은 8주간의 저강도 자전거 에르고미터 운동프로그램이 혈중지질(TC, LDL-C, HDL-C, TG, TC/ HDL-D에 미치는 영향을 규명하는데 있다. 연구의 대상자는 서울시 K대 여자학생 중 각종 질병이 없고, 건강 상태가 양호한 16명을 무작위 표집하고, 두 집단으로 구분하였다 · 실험집단(8명), 통제집단(8명). 실험전 실험집단의 최대심박수를 측정하기 위하여 Bruce Protocol로 운동부하 검사를 실시하였다. 혈액검사는 훈련 전과 훈련 4주 후, 훈련 8주 후에 전완 정맥에서 채혈하였다. 실험집단의 운동프로그램은 (1) 운동강도와 기간은 각자의 60%HRmax인 저강도로 주 3회, (2) 운동시간은 20분부터 시작하고 2주마다 10분씩 증가, (3) 운동기간은 8주. 자료 분석은 두 집단과 처치기간에 따른 실험변인(TC, LDL-C, HDL-C, TG, C-Ratio)에 미치는 반응을 검증하기 위해 2(실험 집단, 통제 집단)×3(훈련 전, 훈련 4주 후, 훈련 8주 후) 반복적 측정의 이원 변량분석 및 두 집단간의 독립적 그룹의 T-test, 각 집단의 처치기간별 반복적 측정의 일원 변량분석을 실시하였다 유의수준은 5%로 하였다. 이러한 절차로부터 다음과 같은 결론을 얻을 수 있었다. 첫째, 두 집단간 처치기간별 TC수준의 차이는 유의하지 않았다. 또한 각 집단의 처치기간별 TC수준에서 실험집단은 유의한 감소를 보이지는 못했다. 통제집단은 유의한 차이가 나타나지 않았다. 둘째, 두 집단간 처치기간별 LDL-C수준의 차이는 유의하지 않았다. 또한 각 집단의 처치기간별 LDL-C 수준에서 실험집단은 훈련 전과 훈련 4주 후에 유의하게 감소하였다. 통제집단은 유의한 차이가 나타나지 않았다. 셋째, 두 집단간 처치기간별 HDL-C수준의 차이는 훈련 전에는 유의하지 않았으나 훈련 4주 후와 훈련 8주 후에서는 유의하게 나타났다. 또한 실험집단의 처치기간별 HDL-C수준에서 유의한 증가를 보이지는 못했다. 통제집단은 유의한 차이가 나타나지 않았다. 넷째, 두 집단간 처치기간별 TG수준의 차이는 유의하게 나타나지 않았다. 또한 실험집단의 처치기간별 TG수준에서 유의한 감소를 보이지는 못했다. 통제집단은 유의한 차이가 나타나지 않았다. 다섯째, 두 집단간 처치기간별 C-Ratio수준의 차이는 유의하지 않았다. 또한 실험집단의 처치기간별 C-Ratio수준에서 유의한 감소를 보이지는 못했다. 통제집단은 유의한 차이가 나타나지 않다. 이상과 같은 결과를 종합해보면 저강도 자전거에르고미터 운동프로그램도 일반 여자대학생들의 혈장지질농도에 긍정적인 영향을 미쳤다. 그러나 콜레스테롤 대사의 전반적 향상을 위해서는 자전거에르고미터의 운동강도를 높이거나 운동기간을 늘여야 할 것으로 사료된다. The purpose of this study is to investigate the effect of low intensity bicycle ergometer exercise program on blood lipid. The subject of this study, 16 fㄷmale university students in Seoul who are health, and have no diseases, are randomly sampled and divided into two groups : experimental group(n=8), and control group (n=8). Pre-test is done the exercise load to measure for HRmax of experimental group using Bruce protocol. I gather blood from antecubital vein of experimental group for blood test at three times, just before test, after 4 week exercise and 8 week exercise. The experimental group takes bicycle ergometer training on these conditions: (1) exercise three times in a week at low intensity of 60^ HRmax, (2) Increase time in 10 Min. at every two weeks, (3) group was trained for 8 weeks. I use statistical techniques for data analysis, 2*3 repeated measure two way ANOVA to determine the differences between tow groups and training times, independent group T-test to determine the differences between two groups, and repeated measure one way ANOVA for training time. The 5% level of significance is utilized. The following results are obtained this study; First, the TC levels of two groups are not significantly different in the training period. Although TC level of experimental goop decrease in after-exercise (4 week, 8 week) to comparison with TC level of before-exercise, it is not significant decrease. And it was no significant difference in control group. Second, the LDL-C levels of two groups are not significantly different in the training period. The LDL-C level of experimental group decreased in after-exercise (4 week, 8 week) in comparison with before-exercise. Specially it decrease significant after 4 week exercise. And it is no significant difference in control group. Third, the HDL-C levels of two groups are not signif4cantly different before exercise, but are significant different after exercise (4 week, 8 week). Although the HDL-C level of the experimental group decrease in after-exercise (4 week, 8 week), but it is not significant decrease. And it is not significant difference in control group. Fourth, the TG levels of tow groups are not significantly different during training period. Although the TG level of experimental group decrease in after-exercise(4 week, 8 week) in comparison with before-exercise, but it is not significant decrease. And it is no significant difference in control group. Fifth, the C-Ratio levels of tow groups are not significantly different during training period. Although the C-Ratio level of experimental group decrease in after-exercise(4 week, 8 week) in comparison with before- exercise, but it is not significant decrease. And it is no significant difference in control group. From the result, because the low intensity bicycle ergometer exercise program effect blood lipids of the female university students, it will contribute for improving health and the prevention adult disease. Synthesizing all the results, low intensity bicycle ergometer exercise program had a positive effect on LDL-C, HDL-C. From the results, Furthermore, In order to maximize the effect of training. it will be better to increase the period of exercise.

제 Ⅲ급 부정교합 환자에서 상악골 전방견인이 성장에 미치는 효과에 대한 연구

성상진,백형선 대한치과교정학회 1994 대한치과교정학회지 Vol.24 No.2

The method of treatment in skeletal Class Ⅲ malocclusion must be chosen according to an etiology and timing of the treatment. Maxillry protraction has been used as an effective treatment method in growing children with maxillary deficiency. The efficacy of maxillary protraction has been viewed as a result of downward-backward displacement of mandible and compensatory dental displacement during the treatment rather than forward-downward growth of maxilla itself. In this study, 104 subjects treated with maxllary protraction, and 19 males and 21 females with known annual growth amount have been chosen longitudinally as treated group and normal group, respectively. And changes in position of maxilla, mandible and dentition have been comparatively analyzed on the lateral cephalometric radiographs by age. The results were as follows: 1. Treated group showed more forward movement of maxilla compare to the normal group and the mandible displaced backward compare to the normal group. 2. Downward movement of mandible in treated group was similar to that of normal group with statistical significance in female 12 year old group and downward movement of mandible in treated group was similar to that of normal group. 3. In treated group, maxillary central incisor moved more forward than the normal group with statistical significance in male 8,10 year-old groups and female 8,9,10 year-old groups. In treated group, downward movement of maxillary central incisor was similar to that of the normal group with statistical significance in male and female 7,8 year-old groups. Considering the above results and the duration of the treatment, the forward movement of maxilla due to maxillary protraction was effective compared to normal growth amount of the normal group.

2-Hydroxyethyl Methacrylate와 5,6-Dihydro-4H-1,3-Oxazine 및 2-Phenyl-1,3,2-Dioxaphospholane의 Zwitterion 공중합에 관한 연구

成墉吉,白形基 동국대학교 1985 論文集 Vol.24 No.-

친수성 poly(2-hydroxyethyl methacrylate) (PHEMA)는 생체 적합성과 안전성이 있는 물질로 생의학적 적용을 하는 데 널리 사용되고 있으나 그 고분자의 기계적 성질과 혈액 적합성이 좋지 않은 것이 아직 개선되어야 할 문제점으로 남아 있다. 그 물질의 물성 및 순도의 문제점 등을 개선하기 위해서 2-hydroxyethyl methacrylate(HEMA)를 5, 6-dihydro-4H-1,3-oxazine(OZI) 및 2-phenyl-1, 3, 2-dioxaphospholane(ethylene phenylphosphonite, EPO)에 대해 촉매를 사용하지 않고 zwitterion 중간체를 경유하여 순수한 공중합체를 합성하였다. 합성된 공중합체들의 특성을 적외선 분광법, 핵자기 공명 분광법, 시차주사 열량계법 및 열무게 측정 분석법에 의해 확인하였고, 또한 그 공중합체들의 물에 대한 팽윤성도 연구 조사하였다. Hydrophilic poly(2-hydroxyethyl methacrylate) has been largely accepted as a biocompatible and stable material for biomedical applications. However, some of its relatively poor mechanical properties and blood compatibilities are still remained as problems to be improved. In order to improve its physical properties and purity problems, some pure copolymers of 2-hydroxyethyl methacrylate(HEMA) with, 5,6-dihydro-4H-1,3-oxazine(OZI) and 2-phenyl-1, 3, 2-dioxaphospholane(ethylene phenyl phosphonite, EPO) have been synthesized via zwitterion intermediates without catalysts. The synthesize copolymers were identified by infrared spectorscopy and nuclear magnetic resonance spectroscopy. the thermal properties of the copolymers were measured by differential scanning calorimetry and thermogravimetry. the swelling properties of the copolymers in water are also investigated.

적혈구 유무에 따른 벤젠, 스티렌, 트리클로로에틸렌에 의한 림프구 중 자매염색분체 교환 빈도

성재혁,김형아,신민정,최미정,이세훈 가톨릭대학교 산업의학센터 2001 韓國의 産業醫學 Vol.40 No.4

This study was performed to investigate the possible role of oxyhemoglobin in the metabolic activation of benzene, styrene and TCE by observing the difference of the SCE frequency between isolated lymphocyte and whole blood lymphocyte cultures exposed to these chemicals. Isolated lymphocyte and fresh heparinized peripheral whole blood samples from a healthy donor(male, smoker) were cultured in the phytohaemagglutinin stimulated culture media for 72 hours. The cells were treated with 100, 300, 1000, 3000 μM benzene, 250, 500, 100, 2000 μM styrene or TCE respectively. Slides were stained with Giemsa's solution for SCE. SCE was analyzed for each subject from coded slides by one researcher. The results were as follows : 1.The frequency of SCE increased dose-dependently with concentration of benzene in isolated lymphocyte and whole blood lymphocyte cultures, however there were no significance. There was no significant difference of SCE frequency between isolated lymphocyte and whole blood lymphocyte cultures. 2.The frequency of SCE in whole blood exposed to sytrene significantly increased in dose-dependant relationship, but not in isolated lymphocyte. The difference of SCE frequency between isolated lymphocyte and whole blood lymphocyte of 2000μM styrene exposure was marginally significant(P=0.0540). 3.In TCE, the frequency of SCE did not increase at any concentration used in this study of isolated lymphocyte and whole blood lymphocyte. Above results suggested that oxyhemoglobin in erythrocytes play an important role in the metabolic activation of styrene but not in benzene or TCE. Key Words : Benzene, Styrene, Trichloroethylene, Sister chromatid exchange, Metabolic activation, Oxyhemoglobin

DNA chip을 사용한 myeloid cell의 유전자 발현분석

박형선,신길상,이미영 순천향대학교 기초과학연구소 2000 순천향자연과학연구 논문집 Vol.6 No.1

Total RNAs were extracted from promyeloid cell(HL60)and myeloid cell(U937). Reverse-transcriptions of the RNAs were performed by using AMV-reverse transcriptase. The RNAs of promyeloid cell and myeloid cell were labelled with fluorescent dye of Cy5-dUTP and Cy3-dUTP, respectively. The reverse-transcribed and labelled RNA was hybridized to a DNA chip containing 384 human cDNAs. Comparative analyses of the gene expression profiles for promyeloid cell and myeloid cell were monitored by gene pie plot or scatter plot, and the gene expression ratios of promyeloid cell/myeloid cell were determined. The expression ratios for thymosin beta-10 gene, immunophilin homolog ARA9/HBV-X associated protein gene, Bcl-w/KIAA0271 actin beta gene and heat shock protein86 gene were determined to be 31%/69%, 26%/74%, 11%/89%, 51%/49% and 79%/2l%, respectively.

차량 시뮬레이터를 이용한 적응순항제어시스템의 성능 평가

남형권,이운성 국민대학교 생산기술연구소 2003 공학기술논문집 Vol.26 No.-

Adaptive Cruise Control (ACC) system can automatically adjust the headway-time and driver vehicle's speed between a driver vehicle and a preceding vehicle. Driving simulator a is virtual reality tool that allows Driver-In-the-Loop Simulation in a laboratory. This paper addresses driving behavior with Adaptive Cruise Control (ACC) system using driving simulator. Participants with different driving styles have driven the simulator with and without ACC through a highway route. Participants are divided by Driving Style Questionnaire (DSQ)-Focus, Speed and Total DSQ scores. Driving behavior in terms of average headway-time, lateral position of a car, and head and gaze movement has been investigated.

病院內 空中眞菌에 관한 硏究

金聖均,崔圭哲,金炯均 조선의대 1984 The Medical Journal of Chosun University Vol.9 No.1

국내 ITA/EA 도입 현황 및 활성화에 관한 연구

김형진,박병선,전성현 한국정보사회진흥원 2005 정보화정책 Vol.12 No.3

IT 환경의 급격한 변화와 소프트웨어 위기 이후 기업의 정보화에 대한 요구는 다양화게 대두되어 왔으며, 최근에는 정보화의 성과가 기대에 미치지 못한다는 불만과 함께 정보화에 대한 투자를 다시 생각해보려는 시각이 일부에서 일고 있다. 이러한 정보화 및 정보화투자에 대한 문제점을 새롭게 해결하려는 노력이 바로 정보기술아키텍처(ITA) 또는 Enterprise Architecture(EA)이다. ITA/EA에 대한 효용성은 미국을 비롯하여 해외 선진국에서 이미 입증되었으며, 현재 국내에서도 ITA/EA에 대한 관심이 날로 높아져 시범사업을 비롯하여 법제화까지 이르게 되었다. 하지만 ITA/EA가 확산되기 위해서는 많은 어려움과 시간을 필요로 하는 것이 현실이다. 향후 국내 ITA/EA 도입 및 활용시 위험부담 최소화와 투자 극대화의 일환으로써 본 연구는 국내 ITA/EA 구축 및 도입기관의 담당자를 대상으로 국내 ITA/EA 도입 환경, 도입 목적, 도입 과정, 도입 결과로 나누어 국내 ITA/EA 도입현황 조사를 통하여 향후 활성화 방안에 대한 연구를 수행하였다.

배열형 전력 MOSFET의 설계 및 제작

김진형,최연익,정상구,박찬광,김충기,성만영 亞洲大學校 1987 論文集 Vol.10 No.-

In this paper, the design of the array type power MOSFETs is discussed in terms of on-resistance, breakdown voltage, placement of FLRs(field limiting ring) and threshold voltage. Also, 9-cell(square-on square grid) VDMOSs are fabricated to confirm the feasibility of the design method. Existence of optimum p-well spacing for minimum on-resistance, which is anticipated by the theoretical results is confirmed by the experiment of the fabricated power MOSFETs. Breakdown voltage of power MOSFET is upgraded by using two FLR's and their optimum placement is determined from the experimental results of the diodes with FLRs. The threshold voltage is controlled by the ion implantation within the design specification. Experimental results are in good agreement with the design specification. Experimental results are in good agreement with the design values. Characteristics of the fabricated power MOSFETs are 190Ω in on-resistance, 270V in breakdown voltage and 2.9V in thershold voltage.

다양한 절삭이송속도로 가공한 A1 7075-T6 소재의 쇼트피닝 전후 피로수명에 관한 연구

김형태,이재헌,신기훈,노승남,서성원 서울産業大學校 2005 논문집 Vol.54 No.1

Aluminum alloy 7075-T6 is ideally used for highly stressed parts such as aircraft components because of its excellent strength to weight ratio. This paper presents a study on the effect of feedrate changes on the fatigue life of A1 7075-T6 specimens before and after shotpeening. For this purpose, five groups of specimens, each of which consists of eight specimens, were first machined at five different feedrates (0.05, 0.10, 0.15, 0.20 0.25mm/rev). Half of eight specimens in each group were then peened and the others remained un-peened. Finally, the fatigue life of each specimen was measured by using 4-point rotatry bending machine. In this paper, comparison of fatigue life among ten sets of specimens is presented. One observation is that the fatigue life of unpeened specimens are inversely proportional to the feedrates. On the other hand, the fatigue life of peened specimens are similarly improved regardless of feedrates except 0.05. Based on the results, it is concluded that shotpeening may improve the fatigue life of Aluminium alloy regardless of feedrates. Therefore, machining productivity may also be increased by choosing higher feedrates for structural conponents that need to be strain-hardened by shotpeening after machining