고양이 위 평활근 수축에 대한 Vanadate와 Pervanadate의 효과

심상수,최효봉,심혜선,이덕주,윤신희,한상준,김명석,조양혁 大韓消化器病學會 1999 大韓消化器病學會誌 Vol.33 No.1

혈압 및 혈관손상에 대한 Candesartan과 Cilnidipine의 병용투여 효능 평가

정상혁,한주희,명창선 충남대학교 약학대학 의약품개발연구소 2014 藥學論文集 Vol.29 No.-

This study was designed to evaluate the effect of candesartan combined with cilnidipine on high blood pressure in spontaneous hypertensive rats (SHRs) and vascular injury induced by cuff-placed neointimal hyperplasia model. To measure blood pressure, low and high doses of candesartan (0.765 and 1.53 mg/kg/day) and cilnidipine (0.96 and 1.92 mg/kg/day) alone or in combination were orally administered in telemetered-SHRs for 2 weeks. To examine the protective action of vascular injury, high doses of candesartan (1.53 mg/kg/day) and cilnidipine (1.92 mg/kg/day) alone or in combination was orally administered for 2 weeks in cuff-induced neointimal hyperplasia model of C56BL/6 mice. As a result, high doses of candesartan and cilnidipine in combination decreased in systolic blood pressure (SBP) and mean arterial pressure (MAP) as compared with monotherapy of high dose of each drug, but not statistically significant. In vascular injury model, candesartan and cilnidipine in combination decreased BrdU-positive cells in neointima and vascular smooth muscle cell proliferation as compared with monotheray of each drug. Thus, these results indicate that the combination of candesartan with cilnidipine is effective for the protection of vascular injury, suggesting this combination to be a valuable tool for the management of vascular remodelling such as restenosis.

고양이 위 평활근에서 KCI에 의한 근수축에 대한 Protein Kinase의 조절

심상수,김승록,심혜선,이덕주,한상준,윤신희,조양혁,김명석 大韓消化器病學會 1998 大韓消化器病學會誌 Vol.32 No.3

두개강내 정맥기형들과 동반된 안와내 해면상 혈관종 1례

조도상,송준혁,김명현,박향권,김성학,신규만,박동빈 대한신경외과학회 1998 Journal of Korean neurosurgical society Vol.27 No.6

미세 전산화 단층 촬영을 이용한 글라스 아이오노머 수복물의 인접면우식 재광화 효과에 관한 장기간 연구

이혁상,김영재,김정욱,장기택 대한소아치과학회 2006 大韓小兒齒科學會誌 Vol.33 No.3

주파수 대역에 따른 워터마크의 강인성 연구

배기혁,정성환 창원대학교 정보통신연구소 2001 精報通信論文集 Vol.5 No.-

Digital watermarking is one of the copyright enforcement schemes that protect copyright ownership. It is a technique which inserts unperceptual ownership information In a given digital data and identifies the owner or distributor of the digital data. In this paper, the robustness of watermark according to frequency bands is studied in many ways. First, we Insert a watermark in each of frequency bands of a digital image and subject the watermarked image to some image processing and attacks. And then we extract the watermark, evaluate the similarity to the original watermark and analyze the robustness of watermarking in each frequency band. In the experimental result, the embedded watermark in the high and low frequency bands is not strong enough for the special processings, including JPEG compression and other attacks. But the embedded watermark in the middle frequency band is relatively strong and excellent in the image preservation. In conclusion, we find that the muddle band is profitable for embedding a watermark generally.

일개 철강 사업장에서 대사증후군의 위험요인과 γ-GTP와의 관련성

문제혁,이상준,박정덕 대한산업의학회 2007 대한직업환경의학회지 Vol.19 No.1

목적: 대사증후군은 심혈관계 질환의 이환과 이로 인한 사망률을 증가시키는 것으로 알려져 있으며, 비만, 고 중성지방혈증, 저 HDL-콜레스테롤혈증, 고혈압, 공복 시 고혈당 등에서 3개 항목 이상을 만족한 경우로 정의된다. 간기능 검사 중 γ-GTP는 간세포 손상에 대한 생체지표로 흔히 사용되는 검사이며, 고혈압, 제 2형 당뇨 및 뇌졸중과도 관련이 있음이 밝혀져 있다. 이번 연구에서는 일개 철강 사업장내 근로자들의 대사증후군의 유병률과 위험요인 및 대사증후군과 γ-GTP와의 관련성을 알아보았다. 방법: 수도권 소재 일개 철강 사업장 남자 근로자 1,604명을 대상으로 대사증후군의 구성요소(체질량지수, 중성지방, HDL-콜레스테롤, 수축기와 이완기 혈압, 공 복 시 혈당)와 γ-GTP, 교대근무 여부, 음주력, 흡연력, 운동 여부 및 가족병력 등을 조사하여 분석하였다. 결과: 일개 철강사업장근로자에 있어서 대사증후군의 유병률은 21.3%, 연령 보정 유병률은 15.5%이었다. 대사증후군에 영향을 미치는 역학적 요인은 연령(OR: 1.063, 95% CI: 1.033-1.094), 음주(OR: 1.657, 95% CI: 1.175. 2.337) 및 흡연(OR: 1.359, 95% CI: 1.017. 1.816) 등 이었고, 교대근무는 고혈압(OR: 1.329, 95% CI: 1.038-1.700)에만 영향을 주었다. 고 γ-GTP 혈증군에서 대사증후군의 구성인자인 비만, 고 중성지방혈증, 고혈압 및 공복시 고혈당의 위험도는 각각 2.625, 3.384, 1.887, 2.406이었고, 대사증후군의 위험도는 3.345이었다. 결론: 이번 연구결과로 볼 때, 철강 사업장에서 대사증후군에 대한 적극적인 관리를 위하여 금주와 금연 등 생활행태 개선을 위한 보건교육이 요구되었고, γ-GTP가 대사증후군의 조기 색출지표로서의 가능성이 제기되었다. Objectives: This study was performed to estimate the prevalence and possible risk factors of the metabolic syndrome in steel-mill workers, and to evaluate the relation between γ-glutamyltransferase (γ-GTP) and the metabolic syndrome. Methods: The study subjects comprised 1,604 male steel-mill workers. The indices of metabolic syndrome, such as BMI, triglyceride, HDL-cholesterol, blood pressure, fasting glucose, and γ-GTP were analyzed in each subject. We collected information about demographic characteristics, behavioral patterns, such as alcohol drinking, smoking, and exercise, and family medical history through a self-administered questionnaire. Statistical analysis was done by using the chi-square test, Mantel-Haenszel trend test and logistic regression model. Results: The crude and age-adjusted prevalences of the metabolic syndrome were 21.3% and 15.5%, respectively, in the steel-mill workers. Age (OR: 1.063, 95% CI: 1.033-1.094), alcohol drinking (OR: 1.657, 95% CI: 1.175-2.337) and smoking (OR: 1.359, 95% CI: 1.017-1.816) were risk factors for the metabolic syndrome. Meanwhile, shift work showed a significant relation with hypertension (OR: 1.329, 95% CI: 1.038-1.700), but not with other metabolic syndrome components. However, tenure, exercise and family medical history were not significant factors for the metabolic syndrome in this study. The risk ratio of the metabolic syndrome (OR: 3.345, 95 % CI: 2.534-4.416) and its components, such as obesity, hypertriglyceridemia, hypertension and hyperglycemia, were higher in the high γ-GTP group (≥63 IU/Ɩ ) than in the controls (<63 IU/Ɩ ). Conclusions: These results confirm the need for health education to control the metabolic syndrome by improving behavioral patterns, such as alcohol drinking and smoking, in factory workers. In addition, it is suggested that γ-GTP might be a useful candidate in screening for the metabolic syndrome.

핏치를 Matrix-precursor로 한 탄소/탄소 복합체의 성질

이보성,주혁종,정발 忠南大學校 産業技術硏究所 1986 산업기술연구논문집 Vol.1 No.1

Using aluminum chloride and copper chloride as a catalyst, coal tar pitches were heat treated and converted into pitch containing more aromatic hydrocarbons. The pitches were used as a matrix precursor for carbon/carbon composite. As a result, a composite after first carbonization up to 1000℃ was shown 4-7% of volume contration. The contration was improved compared with that of resin matrix precursor. In order to increase the density of composite, the composite was imptegnated and recarbonized 4 times with molten pitch and increased up to 1.72g/㎤. The composite based coal tar pitch was shown in higher modulus than the composite based with resin.

임진왜란 관련 한일 역사서사문학의 성격 : <임진록> 과 <태합기(太閤記)>· <조선정벌기> 의 비교를 중심으로 Focusing on the comparative study between " Imjinrok " and " Taikouki " , " Chosenseipatski "

설성경,최문정,권혁래 국제비교한국학회 2002 비교한국학 Comparative Korean Studies Vol.10 No.1

On the subject of Japanese invasion of Korea in 1592(briefly called Imjin Invasion), it was studied for the character of Korea-Japan historic literature; Imjinrok, Taikouki, Chosenseipatski. The approach was made focusing on the environment, narrative method, plot and the characters, consciousess of writers etc. This discussion can be briefed out as follows. First of all, Imjinrok of Chosun Dynasty has been written with a great influence from both practical literature and historic description after Imjin Invasion. The Chronicle recording can counted as one of the major method of narration. The Japanese works such as Taikouki and Chosenseipatski were made on the tradition of military literature of previous generation. One of distinctive feature is the beautification and the heroism that is introduced as the repose for the defeated. It comes from the intended efforts to shape the works as the historical records outwardly, continuously following the trend of military records of previous generations. When the plot is compared, it is as follows, It can be categorized on the narrative novels; before the war, in the beginning of the war, in the midst of war, in the end of war, Three different copies of Imjinrok are almost identical with the stage as the midst of war as the historical records. However, it shows big difference in the peace treaty is made after the death of Toyotomi Hediyoshi, but the Hangul version presents that the Samyunhdangs heroic story over the Japanese after the General Lee Sunsin furthering the final ending with colonialism over Japan. It is one of the important pattern that the important pattern that the writers consciousness is found from post-war novels, even in the historical narration. The plot of Taikouki is composed as two parts: the combat story telling the invasion to the Chosun and the non-combat story showing the personal glorification of Toyotomi. The combat story showing the personal glorification of Toyotomi, The combat story is generally written with victorious events of Japanese military and the sudden final end without a clear description over peace treaty with Ming Dynasty and the defeat of Japan. In the middle of the combat story, it is full with non-combat statement and anecdote designed to chant the glorious Toyotomi and his ruling. On the contrary, two works of chosenseipataki is filled with the combat story on the whole. The first half of the Hori-copy makes the description comparatively as it is, but the second half relatively centered on the battle against Ming. On the non-combat narration, it shows the strong will of the writer who is going to emphasize the ideology of Japanese king. The Oseiki-copy is similar with the Hory-copy, but it is added up with new anecdotes with extended explanation for some simple contents, particularly on the heroism for Toyotomi and the martial story of Gato and Konisi. The comparison between the chosun and the Japanese is tried from different perspectives of counter partner each other: Imjinrok with the brutal and avaricious hegemony of the Japanese, Tailouki and Chosenseipatski with the lustful and extravagant, incompetent martiality of the Chosun. Compared with characters and consciousness of writer, Imjinrok represents the type of royal personality and the inevitable Gods providence in detail. For the Chosun Dynasty, it is counted as the winning forces: civil volunteer soldiers, the royal military warlords, foreign troops from Ming Dynasty, the Royal ministers asking the augmentation troops of Ming. Among the three copies, it brings about the active roles of commanders of civil volunteer forces and generals, remarkably displaying royalty and patriotism. Meanwhile, Lee Sunsin is shaped as the most important character form lots of commanders. Out of the defeated generals, it is presented with the outstanding character with fidelity, surpassing over victorious generals. On the other works, the dispatched troops of Ming seems to play a decisive role in the descriptive narration. It can mean the meritorious achievement in the history, but it seems for the writer to consider Ming as the God-sent troops. What draws the attention is the active involvement of characters who is praised with superpower of with deity. On the Chinese copy of Kukdo, this phenomenon is found with partial involvements, but on the Hangul copies with decisive and overall roles. From the Hangul copies, it is understandable with detailed pattern as a the providence of a God, theorized with untouchable presence of the Chosun Dynasty whom is protected by an Heavenly God and the Budda from any Japanese intrusive invasion. In connection with the reality in fact, the recognition of the God providence is quite superficial, resulting in the evidence of conservative ideology of actual politics. The writers of Tiakouki and Chosunseipatski tried to depict the ideal supreme commander and warriorship with the introduction of characters: Toyotomi Hideyoshi, Gato Kiyomasa, Konisi Yukinaga etc. It seems to foster the warrior spirit by the guideline of warrior way for the next generation. It is also originated from the intention to serve repose of the Toyotomi family, which is defeated by the Tokugawa Shogun.

개에서 관찰된 모기질세포종의 증례보고

조성환,손화영,김혜성,최종윤,류시윤,박배근,윤원기,홍성혁,김덕환 충남대학교 수의과대학 동물의과학연구소 2002 動物醫科學硏究誌 Vol.10 No.-

Pilomatricoma was histopathologically diagnosed in a 2.5-year-old male Alaskan malamute. The patient was referred to Chungnam National University, Veterinary Medical Teaching Hospital with solitary, firm and well-circumscribed mass at shoulder. Grossly, the mass was dome shaped to tumor like and 10 x 8 x 5㎝ in size. Some lesions had gritty or bony consistency and was chalky when sectioned Histopathologic feature included mumerous clusters of tightly arranged, basaloid cells with evenly distributed chromatin and ghost cells were characterized by a central unstained zone. The ghost cells often become calcified and osseous metaplasia was also present.