韓國 正常成人의 大腦機能 側向上 : Dichotic Listening 檢査를 이용하여 With Dichotic Listening Test

朴相學,楊秉換 大韓神經精神醫學會 1982 신경정신의학 Vol.21 No.1

The authors surveyed lateralized functions of the cerebral hemisphers with the dichotic listening in the subjects of medical personnels and medical students of Chosun university, 36 males and 50 females, all of whom were regarded as strong right handers with the preliminary study with Annett's (1970)method for handedness. The results were as follows: 1. In the study with words, they answered to 38.93 ±8.78(53.40%) out of 72 words of the dichotic listening test, either correctly or incorrecty; the number of correct answers was 31.51 ±10.03(42.90%) and that of incorrect ones was 7.41 ±4.30(10.52%) words. 2. In the above study of dichotic listening, both the scores of total answers and correct answers were significantly higher in female than in male(P<.005) 3. In the correct answers of this study, the number of words through right ear was 18.64±6.65 and the number of words through left ear was 12.5 ±6.24, revealing that right ear was dominant in the perception of words. 4. In th study with th digits, they answered to 50.50 ±12.84(63.13%) out of 80 pairs of digits of the dichotic listening test, either correctly or incorrectly; the number of correct answers was 31.24 ±11.69(39.05%) and that of the incorrect ones was 19.78 ±8.93(24.72%). 5. In the above study with answers of digits, both scores of the total answers and correct answers were significantsy higher in female than in male(P<.005). 6. In the study with correct answers, the right ear was dominant in the perception of digits(P<.005); the number of digits through right ear was 18.01 ±7.87 and the number of digits through left ear was 13.23 ±8.38.

한국에서 한 일간지 신문기사 검색을 통한 IMF 전과 후의 자살 양상 비교

박상학,김경환,김학렬,김상훈,표경식,조용래 조선대학교 부설 의학연구소 2000 The Medical Journal of Chosun University Vol.25 No.1

Objectives : Under an IMF bailout program, our country's financial situation forced people to change many things suddenly. Therefore, this study was attempted to search the aspects of changes of suicide attempts in order to find out how the financial crisis affects people's suicide attempts, the extreme repertoire for psychological change Method : November 21, 1997, the day issued the application of IMF bailout program, is the basic date for comparing the changes, on a certain newspaper(Dong-A daily newspaper). The condition was divided into two, namely before and after the basic date, and the characteristics of suicide were compared between two conditions. Results : The news of suicide increased more after than before the application of IMF situation. (before:105, after:158) Specially, for 30-50 years old, active age in community, the rate of suicide attempts reached twice than that of the others. After the IMF situation, the prominent reason of suicide was the financial crisis. For the type of suicide, the family suicide was remarkably increased after the IMF situation. Conclusion : The frequency of the news of suicide was higher after than before IMF bailout program. The major reason of suicide was the financial crisis. Considering that the social and economic crisis affects people's view of death, psychosocial interventions are necessary for their mental health.

중·장거리 선수들의 강력한 스프린트성 반복운동후 혈장 젖산, 젖산탈수소효소 및 젖산탈수소 동위효소의 변화

이규성,김학렬,최용어 韓國體育大學校附屬 體育科學硏究所 1992 韓國體育大學校附屬 體育科學硏究所論文集 Vol.11 No.1

훈련된 중, 장거리 런너를 대상으로 강력한 스프린트성 운동(400m)을 반복적으로 수행하였을때 유발되는 형중 젖산농도, 젖산탈수소효소 및 젖산탈수소 동위효소의 변화를 평가함으로서 무산소성 운동에 대한 LDH 활성도의 특성을 재검토하고 이러한 무산소성 운동을 반복적으로 실시함으로서 유발되는 생체의 스트레스 및 근섬유 동원양상을 평가하고자 400m 트랙을 이용하여 강력한 스프린트 운동을 10회 동안 반복적으로 수행 하였다. 혈중 젖산농도, 젖산탈수소효소 및 젖산탈수소 동위효소를 분석하기 위한 혈액샘플은 400m 질주후 5분의 유식을 취하는 중 3분 경과시에 약 5ml의 혈액을 채혈 하였으며 혈액쌤플의 일부는 혈중 젖산농도를 분석하기 위하여 0.3M Perchloric acid 1000ul에 전혈 200ul를 첨가하고 30초간 진탕한후 원심분리하여 제단백 하였으며 상충액을 냉동보관하였다. 상충액은 1120ul Regent를 혼합하고 실온에서 60분간 방치한후 파장 340nm에서 time scan법으로 측정 하였다. 남은 혈액샘플은 혈장을 분하 하였으면 Beckmann Paragon 법을 이용하여 tltal LDH 활성도를 측정 하였다. 또한 LDH isozyme은 전기영동법으로서 Agarose gel을 사용하여 5개의 동위효소를 분리야였으며 scanning densitometer를 이용하여 상대적 %를 산출하였다. 스프린트성 반복운동에 따른 혈중 젖산농도는 안정시에 비해 1회 400m 질주 후 크게 증가된 수준(p<0.00001)을 나타내었으나 10회 질주가 반복될때가지 더이상의 유의한 증가 없이 전체적으로 일정한 수준을 유지 하였다. 그러나 total LDH 활성도는 혈중 전산농도와는 달리 안정시에 비해 400m 반복힛수에 따라 점차적으로 증가되는 경향을 나타내었으며 9회 400m 반복질주까지 안정시 수준과는 유의한차가 없었으나 10회 400m 질주후 증가수준은 안정시 수준보다 유의하게 높은 수준(p<0.01)을 나타내었다. 또한 total LDH 활성도의 상대적 %로 나나탠 LDH isozyme은 H-type(LDH1+2)의 경우 안정시에 비해 400m의 반복운동에 따라 감소되는 경향을 나타내였으며, 특히 LDH2에서 반복질주간에 통계적 유의차(p<0.01)를 나타내었다. 반면에 M-type(LDH3+4+5)은 반복 운동의 빈도에 따라 점차적으로 증가되는 경향을 나타내었으며, 특히 LDH4와 LDH5에서 현저하게 큰 증가경향을 나타내었다(p<0.001). 이러한 변화양상에 따라 M/H Subunit ratio가 점차적으로감소되는 경향을 나타내었으나 유의한차(p>0.05)는 없는 것으로 나나났다. 결과적으로 본 연구에서의 400m 반복적 질주에 따른 혈중젖산, total LDH 활성도 및 M-type LDH isozyme은 크게 증가를 나타내었다. 이러한 연구결과가 시사하는 바는 400m 반복적 질주에 따른 높은 혈중젖산의 축적이 증가된 totlal LDH 활성도와 M-LDH isozyme분포와 밀접한 관련성을 나나탠다는 것을 시사하는 바이다. The Purpose of this study was to-examine the profile of Lactate dehydrogenase activity during exercise by evaluating a changes of blood lactate concentration, LDH and LDH isozymes induced as a strenuously performed repetitive exercise(400m). Also, it was estimated from a physiological stress and recruitment patterns of muscle fibers indueced as an anaerobi exercise performed. Ten elite middle and long distance runers were employed for this study. Exercise protocol utilized a 10th 400m sprint run. Blood sample for analyzing the blood lactate concetration, lactate dehydrogenase, lactate dehydrogenase isozymes was collected at 3min out of rest period of 5min after 400m maximal run. One portion of the blood sample for analyzing a lactate concentration was deprotenized from 0.3M perchlioric regent to analyze a blood lactate cocnetration was measured by time scan methods in 340nm wave length after 60min ambient temperature. The reminder of the blood sample was stored in refrigerator after centrifuge. Total LDH activity of plasma was examined by using Beckman Paragon tchniques. Also, LDH isozymes was determined to electrophoresis separation by using agarose gel buffered by paragon LD isoenzymes kit. These distribution of LDH isozymes was calculated from a relative percentage by scanning densitometer. Blood lactate concentration followed strenuous repetitive exercise(400m) was shown significantly increased levels (p<0.0001) from 1th to 10th 400m maximal run in comparison with levels of rest. However, it was sustained a const.ant levels without more significant increase from 1th maximal run to 10th run. Total LDH activity showed a progressivly shift, trend as 400m run went on repetitively but, there was not significant difference(p>0.05) from rest levels to 9th maximal run. However, total LDH activity after the 10th 400m maximal run showed significantly increased levels(p <0.01), compared with rest levels. Also, distribution of LDH isozymes determine as relative percent.age of total LDH activity was displayed a decreased levels in case of H- specific type(LDH1+2) by increasing of 400m repetitive frequency. Especially, there displayed a significant difference(p<O.O1) in the LDH4 between 400m repetitive run. Wheareas, M- specific type(LDH3+4+5) was shown a increased levels by increasing of 400m repetitive frequency. Especially, there was significant difference (p <0.001) in the LDH 4 and LDH5. H/M subunit ratio followed changes of LDH isozymes distribution was shown a decreased levels, but there was not significant difference(p >0.05). In Conclusion, The results of this study showed a increase in blood lactate concentration, total LDH activity and M -type LDH isozymes. It was suggested that increase levels of blood lactate accumulation followed 400m repetitive maximal run was a close relation with the increase levels of total LDH activity, and M-LDH isozymes distribution.

Antioxidant and cytoprotective effects of enzyme‐extracted constituents of Protaetia brevitarsis seulensis powder

Choi In‐Hag,Choi Sung‐Up,Son Jin‐Sung,Jang Woo‐Whan,Chung Tae‐Ho 한국곤충학회 2021 Entomological Research Vol.51 No.2

This study was aimed to compare the antioxidant and cytoprotective effects of hot‐water and enzyme‐extracted constituents of Protaetia brevitarsis seulensis powder. The products of enzymatic extraction had 1,1‐diphenyl‐2‐picrylhydrazyl (DPPH)‐radical‐scavenging activity, cytotoxic effects, and provided cytoprotection against H2O2 and intracellular reactive oxygen species. Enzymatic extraction improved DPPH‐radical‐scavenging activity relative to hot‐water extraction (P < 0.05), with inhibition rates of 33% at 500 μg/mL and 35% at 1000 μg/mL. Cell viability ranged from 100 to 122%, and was higher for hot‐water than for enzymatic extraction (P > 0.05). Hot‐water extraction achieved greater cytoprotection against H2O2 than enzymatic extraction. However, enzymatic extraction achieved greater antioxidant and cytoprotective activity against reactive oxygen species than hot‐water extraction. These results provide evidence of the antioxidant and cytoprotective effects produced by enzymatic extraction of the active ingredients from Protaetia brevitarsis seulensis powder.

치근단 병소의 임상적 연구

김상우,우순섭,유임학,이영수,심광섭 대한악안면성형재건외과학회 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.3

The purpose of this study was to find the clinical features of periapical lesions. A total of 130 periapical lesions which were obtained from biopsy and diagnosed histopathologically as periapical cyst, periapical abscess, and periapical granuloma at the Department of Dentistry in Hanyang University Hospital were throughly analysed according to the distribution and incidence of age, sex, location, and so on. The following results were obtained : 1.Out of 130 periapical lesions, 88 cases(67.7%) were periapical cysts, 30 cases(23.1%) were periapical abscesses, and 12 cases(9.2%) were periapical granulomas. 2.The periapical lesions occurred most frequently in the third decade, and followed by the fourth, fifth, sixth, and second decade. The periapical cysts occurred most frequently in the third decade(26.1%), the periapical granulomas in the fourth decade(33.3% ) the periapical abscesses in the sixth decade(26.7%). 3.The periapical lesions were more frequent in men than in women with the ratio of men to women of 1.4 : 1. The radio of men to women of periapical cysts was 1.6 : 1, that of periapical granulomas was 0.5 : 1, and that of periapical abscesses was 1.3 : 1. 4.The periapical lesions were more frequent in maxilla than in mandible with the ratio of 1.2 : 1. The ratio of maxilla to mandible of periapical cysts was 1.5 : 1, that of periapical granulomas was 0.5 : 1, that of periapical abscesses was 1 : 1. 5.The most commonly involved location of the periapical lesions was maxillary anterior teeth(40.8%), and followed by mandibular molars, mandibular premolars, and mandibular anterior teeth and maxillary molars. The most frequent location of the periapical cysts was maxillary anterior teeth(48.9%), that of periapical granulomas was mandibular molars(50.0%), that of periapical abscesses was mandibular molars(40.0%).

회귀구조에 따른 예측신경망의 음성인식 성능비교

한학용,김주성,허강인 東亞大學校 附設 情報通信硏究所 1998 情報通信硏究所論文誌 Vol.6 No.1

In this paper, we compare the recognition rate between Recurrent Prediction Neural Networks and CHMM according to increasing the prediction order, the number of hidden units for RPNN and the state for CHMM. We perform the recognition experiment of Korean 100 syllables and ETRI's SAMDOLI Speech DB. In the DIGIT syllables, the recognition rate of Neural Networks, 98.5%, similar to CHMM, 99%, of the 5 state numner. In the 100 syllabes, the Jordan's RPNN which based on the number of hidden units is larger than 25 units shows the higher reocgnition rate than CHMM of the 5 state number. When CHMM based on the 6 and 7 state, RPNN's recognition rate is lower than CHMM.

인후두부 이상감 호소환자의 임상적 연구 : SCL-90-R을 이용하여

박상학,김상훈,도남용 朝鮮大學校 附設 醫學硏究所 1991 The Medical Journal of Chosun University Vol.16 No.1

To study the clincal characteristics of Globus hystericus, the authors assesed 37 out-patients with globus sensation as their main subjective symptom, the organic causes of which were ruled out as possible. We used Symptom Check List-90-Revision(SCL-90-R) to investigate the difference between globus hystericus and normal control group. The results were as follows: 1. Globus hystehcus tends to occur mainly above 4th decades and more common in female than male in low educational level (M:F=1:2.7). 2. Interval between symptom onset and consultation, 24% of patients are within 1 month of onset, but 33% of patients are after 1 year of onset. 3. The most common complaints were sore throat(73%) and foreignbody sense (70.3%) in globus hystericus. 4. In SCL-90-R scales, mean T-scores of globus hystericus on somatization, anxiety, Psychoticism, global severity index, Positive symptom distress index(all P<.0001), additional index (P<.005), hostility (P<.01), depression(P<.01), and obsessive compulsive(P<.01) subscales were significantly higher than normal control.

조선대학교 의과대학 의학과 학사편입제도의 전향적 검토

임성철,박상기,도남용,박상학,이승일,송창훈,박종 朝鮮大學校 附設 醫學硏究所 1998 The Medical Journal of Chosun University Vol.23 No.1

There are many advantages and disadvantages under the limited bachelor's admission system. To diminish the demerits and to increase the merits of this system, the authors posed questions to the faculties and students of the Department of Medicine. Chosun University College of Medicine and other colleges in Korea. The questionnaire was made according to trends and feelings in this system. We received a lot of information and suggestions as to how to improve the system, in the following paper we discuss and report the prospective aspects of the bachelor's admission system.

남성 성기자해

김상훈,문남식,황걸,박상학,김학렬,김경환 朝鮮大學校 附設 醫學硏究所 2005 The Medical Journal of Chosun University Vol.30 No.2

Background and Objectives: Intentional self-mutilation of the genitals in male is exceedingly rare. As the authors experienced 3 cases of male genital self-mutilation while psychotic, we investigated with psychiatric points of view including general and psychiatric characteristics of genital self-mutilation in Korea. Materials and Methods: Total 21 cases of the genital injury were obtained from the index book of Journal of Korean Neuropsychiatric Association and the Electronic Library Search Engine. From these, excluding the 4 accident-caused cases of penile amputation, the authors investigated 17 cases in terms of general epidemiological characteristics, the type of mutilation, diagnostic classification, psychodynamics of their behavior. Results: Epidemiological data showed that the most of the genital self-mutilation cases are twenties (52.9%); most are single (64.7%). In terms of the mutilation types, complete transection of penis type were committed most frequently (72.1%). The formal diagnoses were mainly schizophrenia (82.3%) and schizoid personality disorder(11.8%). Psychodynamically, lots of cases could be explained as to punish failures in the male role (20.6%), related to religiosity (14.7%), and related to physical pain or somatic illness (14.7%). Conclusion: We are unable to say exactly what prompts a man to divest himself of his genitals. On the basis of 17 cases, we are willing to hazard several risk factors. For individuals psychotic at the time of act there seem to be at least three paradigmatic at-risk groups: (1) younger acutely psychotic men with related to cure or punish failures in the male role, (2) the men with personality disorders who act rageful feelings against themselves and/or close objects, and (3) sociocultural factors known to contribute to such an act include some complex religious belief regarding purification or resisting temptation. Psychological factors yet undetermined may be' equally important.

의과 대학생의 심리적 특성과 학업 성취도와의 관계

박상학,박찬원,조용래 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.5

연구목적 : 의과대학생들의 심리적 특성을 조사하여 이러한 특성과 학업 성취도와의 관계를 알아보고, 더 나아가 그들의 학업 성취도를 예견할 수 있는 요인을 탐색해보고자 하였다. 방 법 : 의과대학 의학과 1, 2, 3학년에 재학중인 학생 489명을 대상으로, 이전 유급 횟수, 여러 가지 심리적 특성들을 자기 보고형 설문지로 조사하였고, 이를 학기말 성적과 비교, 의과 대학생의 심리적 특성과 학업 성취도의 관계를 조사하였다. 결 과 : 1) 유급 경험자는 34.3%, 편입 경험자는 6.7%였다. 유급 경험 횟수는 1회부터 6회까지였다. 2) 이전 유급 경험은, 성적(G.P.A), 수행 불안, 자기 효능감과 각각 유의한 부적 상관을 나타낸 반면에, 시험 불안과는 유의한 정적 상관을 나타냈다. 이전 유급 경험은, 우울, 자기 불일치, 상태 불안등과 유의한 상관을 보이지 않았다. 3) 학업 성취도는 성별 및 자기 효능감 양자 모두와 각각 유의한 정적 상관을 나타낸 데 비해, 우울, 자기 불일치, 시험 불안, 상태 불안등과는 유의한 부적인 상관을 보였다. 4) 나이, 성, 편입경험, 유급, 우울, 자기불일치, 시험 불안, 상태 불안, 수행불안, 자기 효능감 등은 학업 성취도의 10.86%를 설명하였다. Objective : Several psychological characteristics of medical students were investigated, the relationship between these characteristics and academic achievement was identified, and futhermore some significant predictors of their academic achievement were explored. Method : Subjects were a total of 489 medical students, 1st, 2nd, 3rd year in Chosun university as of in 1998. We administered self-report questionnaires including age, sex, grade failure, and transfer experience. And Beck Depression Inventory, Achievement Self-Discrepancy Scale, Self-Efficacy Scale, State-Trait Anxiety Inventory(state), Test Anxiety Scale, and the Inventory of Performance Anxiety were handed out to them on April 1998. After the semester, we examined the academic achievement according to grade point average. Person's correlations were calculated to explore the relationships between grade failure and other psychological variables, as well as the relationships between academic achievement and other psychological variables. The amount that academic achievement was explained by the psychological variables was obtained using multiple regression analysis. Result : 1) In 489 students, grade failure was 168(34.3%), non-failure was 321(65.7%), and transfer was 33(6.7%). 2) While G.P.A., performance anxiety, and self-efficacy, respectively, were negatively correlated with the failure, test anxiety was positively correlated with the grade failure. There were no statistically significant correlations between grade failure and depression, self-discrepancy, or state anxiety. 3) Academic achievement was positively correlated with both gender and self-efficacy, whereas it was negatively correlated with depression, self-discrepancy, test anxiety, and state anxiety, respectively. Female students were better than males in academic achievement. 4) The amount that age, gender, grade failure, transfer, depression, self-discrepancy, test anxiety, state anxiety, performance anxiety, and self-efficacy accounted for academic achievement was 10.86% totally. Conclusion : Gender, grade failure, and depression in medical students affected their academic achievement significantly.