이상설 : 한국 근대수학교육의 아버지

설한국,이상구,Seol, Han-Guk,Lee, Sang-Gu 한국수학사학회 2009 Journal for history of mathematics Vol.22 No.3

본 논문은 한국수학사에서 연구와 정리가 취약한 시기인 근대수학의 도입기를 조사하면서, 그 근대수학의 도입기에서 만나게 되는 인물인 이상설(李相卨)에 대한 조명을 시도한다. 시대적 상황이 모든 분야의 침체기를 가져온 구한말 이상설은 근대수학에서 당대를 대표하는 높은 학식을 쌓고 뛰어난 재능을 보여주었다. 그간 이상설에 대해 '근대수학교육의 아버지'라는 평가가 없지 않았음에도 불구하고 낯설게 느껴진다면, 그것은 그가 독립운동가로만 강하게 각인된 탓일 것이다. 하지만 그는 19세기말 조선 근대수학의 첫 번째 교과서 편저자이자 수학교사이기도 했음을 새겨둘 필요가 있다. 대유학자이면서도 선구적으로 외국어와 서양과학 특히 근대 서양수학을 이해한 면모는 한국이 배출한 천재 중 하나라는 평가가 결코 과장이 아님을 보여준다. 이에 본 논문에서는 한국 근대수학교육에 커다란 기여를 한 인물인 이상설의 교육과 학문 및 실천업적을 조명한다. 보재 이상설이 1886년경에 쓴 책 <수리>와 최초로 수학과 과학을 관립교육기관의 교육과정에 편성한 과정, 최초의 근대수학교과서로 여겨지는 <산술신서>의 발간, 민족교육기관인 '서전서숙'의 설립 및 운영을 포함한 보재의 업적을 한국수학사 관점에서 조명한다. 또한 <산술신서>의 목차와 구체적인 내용 및 1901년에 출간된 <신정산술>의 내용을 소개하고, 지금까지 부정확하게 알려진 <수리>와 <산술신서>에 관한 몇 가지 역사적 사실을 발굴하여 재조명한다. Most who have heard of Sang-Seol Lee know him for his contribution to the Korean independence movement nearly a hundred years ago. This paper, however, will discuss Lee's other great contribution to his country; that of being "The father of modern mathematical education in Korea". Lee passed the rigorous government officer examination with the highest honor and became a teacher for the royal prince. Later he became the president of Sunkyunkwan, a national institute of higher learning since 1398, and eventually a well-known university bearing the same name. Lee was also a highly regarded Confucian scholar and well versed in foreign languages. He wanted Korea to become a modern country and felt that the areas of science and engineering were studies that needed improving in order to achieve modernization. While researching Western textbooks on the subjects he realized that Western mathematics would be especially important for Korea. With that, it became his mission to integrate Western mathematics into the Korean educational system. This paper will explain the importance of Sang-Seol Lee's contributions to mathematic education in Korea and how it helped Korea become the modern nation it is today.

Performance of electrochemical double layer capacitors using highly porous activated carbons prepared from beer lees

Sang Guk Lee,Hee Moon,Kwang Hyun Park,심왕근,M.S. balathanigaimani 한국공업화학회 2011 Journal of Industrial and Engineering Chemistry Vol.17 No.3

Beer lees precursor is chosen to prepare activated carbons having different physical and chemical properties. The beer lees-based activated carbons (BL-ACs) are characterized by N2 adsorption/desorption isotherms, adsorption energy distributions (AEDs), and X-ray photoelectric spectroscopy (XPS). Furthermore the electrochemical properties of the BL-ACs are assessed using cyclic voltammetry (CV), electrochemical impedance spectroscopy (EIS), and constant current charge/discharge method. The maximum specific capacitance (about 188 F/g at discharge current of l mA/cm2) is obtained in 0.1 M H2SO4 electrolyte solution, which is a relatively low electrolyte concentration. The overall results suggest that the BL-ACs are good candidates for EDLC electrode materials.

흰쥐 성장기간에 따른 Xylene의 독성에 관한 연구

이혜자,이상희,전태원,이상일,윤종국 대한의생명과학회 2000 Journal of biomedical laboratory sciences Vol.6 No.3

실험동물에 있어서 연령 차이에 따라서 xylene 독성이 어떠한 차이가 있는지를 검토하는 일환으로 5주령 및 12주령 흰쥐에 50% m-xylene을 체중 100 g 당 0.25 ml씩 1회 투여한 다음 24시간 후에 처치하여 다음과 같은 결과를 얻었다. Xylene 투여로 인한 요 중 methylhippuric acid 함량은 5주령군이 12주령군에 비해 현저하게 높게 나타났다. 그리고 간조직 중 cytochroms P-450 함량은 대조군에 있어서 5주령군이 12주령군 보다 약 50% 정도 낮게 나타났으나 xylene 투여로 인한 cytochrome P-450 함량 증가율은 12주령군 보다 5주령군에서 높게 나타났다. 간 alcohol dehydrogenase 활성치도 대조군에 있어서는 5주령군이 12주령 보다 약 35% 정도 낮게 나타났으나 xylene 투여로 인한 본 효소의 활성 증가율은 5주령군에서 오히려 높게 나타났다. 그러나 간 aldehyde dehydrogenase 활성치는 대조군 및 xylene 투여군 모두 5주령과 12주령간에 유의한 차이를 나타내지 않았다. 한편 xylene 투여시 체중 당 간무게, 간조직 malondialdehyde 함량 및 혈청 ALT 활성 변동을 통하여 간손상 정도를 상호 비교 관찰하였을 때, 12주령군이 5주령 실험동물 보다 간손상이 다소 심하게 나타남을 알 수가 있었다. 이상 실험결과는 연령에 따라 xylene에 의한 간손상의 차이는 이물질의 생체내 대사율이 달리 나타나기 때문일 것으로 생각된다. To evaluate an effect of aging on the xylene toxicity, 50% m-xylene in olive oil (0.25 ml/100 g body wt.) was administered to 5 week and 12 week-old rats one times intraperitoneally and sacrificed at 24 hrs afterwards. The increasing rate of urinary H-methylhippuric acid concentration was higher in 12 week-old rats than 5 week-old rats by the treatment of m-xylene. On the liver function findings, i.e., liver weight/body weight (%), serum levels of ALT activity and hepatic malondialdehyde content, 12 week-old rats showed more severe liver injury than 5 weeks those in xylene-treated rats. And the hepatic cytochrome P-450 contents was higher in 12 weeks rats than those of in 5 week-old rats, but the increasing rate of that was lower in 12 week-old rats. Hepatic alcohol dehydrogenase activity was also higher in 12 week-old rats than in 5 week-old rats whereas the increasing rate of that was higher in 5 week-old than those in 12 week-old rats by the xylene treatment. Furthermore, the hepatic aldehyde dehydrogenase activities were no differences between the 5 and 12 week-old rats both in the control and xylene-treated group, In conclusion, age may influences upon the hepatotoxicity with xylene and it may be responsible for xylene metabolism in rats.

야뇨증 환아들의 심리사회적 특성에 대한 다기관 연구 : 행동 및 정서 문제를 중심으로

조수철,김재원,신민섭,황준원,한상원,박관현,이상돈,김경도,김건석,서홍진,이유식,정재용,김영균,문두건,남궁미경,한창희,조원열,김영식,배기수,이종국,정우영,신의진 大韓神經精神醫學會 2005 신경정신의학 Vol.44 No.6

Objectives : The aim of this study was to examine the behavioral and emotional problems associated with nocturnal enuresis in Korean children. Methods : Three hundred eighteen children with nocturnal enuresis, together with their parents, completed the Child Behavior Checklist (CBCL), Disruptive Behavior Disorder Scale according to DSM-IV (DBDS), Children's Depression Inventory (CDI), State-Trait Anxiety Inventory for Children (STAIC), and Piers-Harris Children's Self-Concept Scale (PHCSC). Ninety-three normal students were selected as the control group. Results : Compared to the normal control group, the mean scores with regard to the withdrawn, social problems, attention problems, delinquent behavior, aggressive behavior, externalizing problems and total problems profiles were significantly higher in the nocturnal enuresis group according to the CBCL results. The nocturnal enuresis group also scored significantly higher in the ADHD and ODD profiles of the DBDS. The nocturnal enuresis group was more depressed and anxious than the control group according to the results of the CDI and STAI. The mean score of the PHCSC was significantly lower in the nocturnal enuresis group when compared to the normal control group. Conclusion : The results of this study suggest that children with nocturnal enuresis in Korea have clinically relevant behavioral and emotional problems. The findings support the link between nocturnal enuresis and psychopathology in Korean children.

종 분포 모형을 이용한 구상나무림의 지속 및 쇠퇴에 관한 연구 - 전라남도 광양시 백운산을 중심으로 -

조선희 ( Seon Hee Cho ),박종영 ( Jong Young Park ),박정호 ( Jeong Ho Park ),이양근 ( Yang Geun Lee ),문이만 ( Lee Man Mun ),강상호 ( Sang Ho Kang ),김광현 ( Gwang Hyun Kim ),윤종국 ( Jong Guk Yun ) 한국산림과학회 2015 한국산림과학회지 Vol.104 No.3

The present study investigated the habitats of Korean fir trees (Abies koreana E. H. Wilson) on Mt. Baekwun (Baekwun-san), determined the current distribution, quantified the contribution of biological and nonbiological environmental factors affecting the distribution, derived actual and potential habitats, presented a plan for the establishment of protected areas, applied RCP 8.5 climate change scenario to analyze the effects of climate change on the future distribution of Korean fir trees, and predicted future potential habitats. According to the results of the study, 3,325 Korean fir trees (DBH >= 2.5 cm) inhabited Mt. Baekwun, and their distribution area was approximately 150 ha. Populations of Korean fir trees were confirmed to exist at an altitude of 900 m above sea level and were distributed up to 1,200 m. Based on potential distribution, areas appropriate for habitation by Korean fir trees were analyzed to be 450 ha, three times the current distribution area, with a focus on Sang Peak (Sang-bong), Eokbul Peak (Eokbul-bong), Ddari Peak (Ddari-bong), and Dosol Peak (Dosol-bong). The forest stands near Sang Peak, the main peak, were evaluated as those with the most appropriate potential for the habitation of Korean fir trees, and populations of the trees tended to prefer the northern slope rather than the southern slope. When climate change scenario RCP 8.5 was applied and future potential distribution was analyzed, the habitats were expected to decrease in area to 20 ha by 2050, with a focus on Sang Peak, and areas appropriate for habitation were predicted not to exist by 2080. Judging from such results, as global warming accelerates, the habitats of Korean fir trees are clearly expected to move from lowlands to highlands.

만성신부전증 환자에서 Recombinant Human Erythropoietin 치료에 따른 혈액지표와 Hemoglobin A1c에 대한 연구

이세영,배성한,변동원,서교일,유명희,김극배 순천향의학연구소 1996 Journal of Soonchunhyang Medical Science Vol.2 No.2

Hemoglobin A1c is produced by a progressive, non-enzymatic reaction between glucose and hemoglobin within the erythrocytes. The HbA1c concentration is dependent on the plasma glucose level and the stage of development of the erythrocytes. Immature erythrocytes contain lower levels of glycosylated hemoglobin than mature erythrocytes. HbA1c level was decreased in short RBC life span. Therefore, HbA1c level is not only measure for assessment of moderate to long term glycemic status in diabetics, but also as a possible diagnostic parameter of anemia. The aim of this study was to evaluate the HbA1c level in patients with chronic renal failure with anemia. HbA1c concentration, iron, ferritin, TIBC and hematologic parameters were measured before treatment and 1, 2 months after administration of recombinant human erythropoietin. The HbA1c concentration was measured by high performance liquid chromatography with cation exchange column (Pharmacia). The results were as follows; 1. The mean of hemoglobin was 8.66 g/dL in the controls and 7.84 g/dL in the patients with chronic renal failure. The mean of hematocrit was 25.19 % in the controls and 23.14 % in the patients with chronic renal failure. The mean of MCV was 93.23 fL in the controls and 92.73 fL in the patients with chronic renal failure. The mean of MCH was 32.56 pg in the controls and 31.76 pg in the patients with chronic renal failure. The mean of HbA1c was 3.15 % in the controls and 2.95 % in the patients with chronic renal failure. 2. Hematologic parameters in the patients with chronic renal failure 1) The results of hemoglobins were 7.84 g/dL, 8.11 g/dL, 8.92 g/dL, the MCH were 31.76 pg, 32.87 pg, 33.20 pg, the results of MCV were 92.73 fL, 97.37 fL, 92.85 fL at before treatment and 1, 2 months after administration of r-HuEpo. 2) The results of hematocrits were 23.14 %, 23.73 %, 26.73 % at before treatment and 1, 2 months after administration of r-HuEpo. 3. Iron metabolism parameters in the patients with chronic renal failure 1) The results of iron test were 180.92 ㎍/dL, 137.79 ㎍/dL, 126.83 ㎍/dL at before treatment and 1, 2 months after administration of r-HuEpo. 2) The results of ferritin test were 1500.2 ng/ml, 1311.6 ng/ml, 1151.0 ng/ml at before treatment and 1, 2 months after administration of r-HuEpo. 3) The results of TIBC test were 282.17 ㎍/dL, 282.45 ㎍/dL, 278.83 ㎍/dL at before treatment and 1, 2 months after administration of r-HuEpo. 4. The results of HbA1c test were 2.95 %, 3.08 %, 3.18 % at before treatment and 1, 2 months after administration of r-HuEpo. It is suggested that, in patients with chronic renal failure, evaluation of HbA1c in diabetics who have anemia with chronic renal failure should be consider possible hematologic parameters, and HbA1c level would be one of the marker of anemia status, but further studies are needed.

하악 이부에 발생한 방선균증의 치험례

李暲東,孫東錫,金成國 대구효성가톨릭대학교 1996 연구논문집 Vol.52 No.2

Actinomycosis is a chronic infection of inhibitant oral bacteria, especially Actinomyces israelii. A. israelii are Gram positive, non acid-fast, anaerobic, filamentous organisms. The most frefguent form of actinomycosis is the cervicofacial type. Its involved skin is purplished red and indurated, tending to form multiple draining sinus tract. The characteristic “sulfur granule”appear in the abscess center. The infection of the soft tissue may extend to involve the mandible or less commomly, the maxilla. The treatment is antibiotic therapy and adequete drainage. We experienced actinomycosis occured in chin area and treated this disease with antibiotics &surgical drainage. The patient showed good prognosis.

방선균주 7489가 생산하는 DNA Topoisomerase 1 저해제에 관한 연구

이동선,하상철,이상용,김종국,홍순덕 한국미생물생명공학회 ( 구 한국산업미생물학회 ) 1996 한국미생물·생명공학회지 Vol.24 No.1

미생물로 부터 topoisomerase Ⅰ저해물질을 탐색하던 중 Streptomyces melanosporofaciens 7489 균주가 topoisomerase 활성을 저해하는 것을 발견하였다. 이에 균주가 생산하는 활성물질을 분리정제한 후 구조를 결정하였고 정제된 물질에 대한 활성을 조사하였다. 균체로 부터 acetone 추출, ethyl acetate 추출, silica gel column chromatography, preparative TLC 및 HPLC등을 통하여 topoisomerase 저해물질 7489-1을 정제한 후 UV, ^1H-NMR, ^13C-NMR, DEPT and EI-MS등의 기기분석을 한 결과 저해물질은 dibutyl phthalate로 결정되었다. 789-1의 topoisomerase Ⅰ 저해활성은 1μM에서 10μM까지 점진적으로 감소하였으며 25μM에서 완전히 저해되었다. During the screening of inhibitor of DNA topoisomerase I from microbial secondary metabolites, Streptomyces melanosporofaciens 7489 which was capable of producing high level of inhibitor was selected from soil. The active compound (7489-1) which was capable of producing high level of inhibitor was selected from soil. The active compound (7489-1) was purified from the culture broth by solvent extraction, silica gel column chromatography and HPLC. The inhibitor was identified as dibutyl phthalate by spectroscopic methods of UV, ^1H-NMR, ^13C-NMR, DEPT and EI-MS. 7489-1 showed a strong inhibitory activity against topoisomerase I with 10 μM of IC_50 value.

음향방출법에 의한 탄소 섬유 복합재료의 인장 및 파괴

이상국,김옥균,남기우,오세규 韓國非破壞檢査學會 1995 한국비파괴검사학회지 Vol.15 No.1

본 연구는 [0°.90°]₂s와 [0°₂/90°₂]s의 2종류 탄소섬유복합재료에 대한 인장 및 파괴인성 시험시의 파괴거동과 음향방출 특성을 해석하고 성형시의 성형압력과 인장강도 및 파괴인성 간의 상관성을 알아내기 위하여 수행되었다. AE신호는 음향방출장비를 이용하여 성형과정, 인장 및 파괴인성 시험중에 각각 검출하였다. 인장강도는 성형가압 단계수가 적을수록, 그리고 [0°/90°]₂s 시험편 쪽이 [0°₂/90°₂]s 시험편보다 높은 강도를 나타내었다. 파괴인성은 동일한 온도영역에서 거의 같은 값을 나타내나 시험온도가 높아질수록 점차 낮아짐을 알 수 있었다. 한편 인장 및 파괴인성 시험시의 파괴거동과 AE신호간의 상관성을 조사하기 위하여 AE데이터의 AE변수들에 대한 후 신호처리(post processing)와 광학현미경 및 주사형 전자현미경 관찰이 각각 수행되었다. The study was carried out to analyze the fracture behavior and the acoustic emission(AE) characteristics and to find the relationship among tensile strength, fracture toughness and cure pressure in cure process of the carbon fiber reinforced composites of two types, [0°/90°]₂s and [0°₂/90°₂]s. AE signals were detected during the curing process, tensile tests and fracture toughness tests by acoustic emission(AE) measurements, respectively. Tensile strengths showed that the less cure pressurizing steps and the side of [0°/90°]₂s specimens had the higher strengths than those of the others. Fracture toughness by change of test temperature showed nearly same values in the same temperature region, but the higher test temperature had the lower fracture toughness values. In order to examine the relationship between fracture behavior of CFRP in tensile and fracture toughness tests and AE signals, the post processing for AE parameters of AE data and the observations of microscope and SEMA have been carried out respectively.

제 2 대구치 발거에 의한 Ⅲ급 부정교합자의 치료효과에 관한 연구

이성희,박영국,정규림 대한치과교정학회 2004 대한치과교정학회지 Vol.34 No.2

이 연구는 제 2 대구치를 발거하고 하악 제 1 대구치의 후방이동을 위해 CPHG(cervical pull head gear)와 경우에 따라 Ⅲ급 고무줄을 사용하여 고정성 교정장치로 치료한 Ⅲ급 부정교합자의 치료전후 안면골 및 치아치조부, 연조직의 평균변화를 알아보기 위해 시행되었다. 평균 ANB 가 -1.4˚ 이고 IMPA가 85˚ 인 중등도이하의 Ⅲ 급 부정교합자 15명을 대상으로 치료전후 측모두부 X-선 규격사진의 평균 두개안면부 측면 중첩모식도를 작성하고 계측 분석한 바, 다음과 같은 결과를 얻었다. 1. 전안면고경에 대한 전하안면고경의 비율은 0.6%증가(P< 0.01)하였고, 하악 평면각이 1.5˚증가(P<0.05)하였다. 2. 전방 두개저에 대한 하악골 위치는 미약하게 후하방회전하였다. 3. 하악 제 1 대구치가 4.06mm(P<0.001)후방경사이동하였고 하악 전치는 설측으로 3.2˚경사이동(P<0.05)하였다. 4. 하순의 후퇴로 인한 안모의 개선이 이루어졌다. 이상의 결과를 종합할 때 골격성 부조화가 중등도 이하인 Ⅲ급 부정교합자에서 하악 제 1대구치의 후방이동을 용이하게 하고 하악 전치의 지나친 설측경사를 피하기 위해 제 2 대구치를 발거하는 것은 조심스러운 증례의 선택시 치료에 유용하리라 사료된다. 그러나 본 연구에서는 제 2 대구치 발거 후 제 3 대구치의 맹출 및 치료후 예후에 대한 장기적인 관찰은 이루어지지 못하여 향후 이에 대한 계속적인 연구가 필요하리라 생각된다. This study aimed at investigating the skeletal, dentoalveolar, and soft tissue changes of Class Ⅲ malocclusion cases treated by second molar extraction. The lateral cephalograms of 15 subjects with moderate Class Ⅲ malocclusion by average ANB -1.4˚ and IMPA 85˚ were traced and the computerized superimposition of average craniofacial change was made. The data was gathered and statistically analyzed. The results were as follows: 1. Lower anterior facial height/anterior facial height increased by 0.6%(P<0.01), mandibular plane increased by 1.5˚ (P<0.05). 2. There was a slightly downward & backward rotation of the mandible. 3. Lower first molar tipped distally by 4.06mm(P<0.001), lower anterior teeth lingually tipped by 3.2˚ (P<0.05). 4. Retracted lower lip improved facial profile. This study may suggest that second molar extraction could be effective for a moderate Class Ⅲ malocclusion to make distalization of the lower first molar easier and avoid severe lingual tipping of the lower incisor, if the lower third molar has a normal shape, good direction of eruption and adequate time for lower second molar extraction.