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      • Ultra Dense Small Cell Networks: Turning Density Into Energy Efficiency

        Samarakoon, Sumudu,Bennis, Mehdi,Saad, Walid,Debbah, Merouane,Latva-aho, Matti IEEE 2016 IEEE journal on selected areas in communications Vol.34 No.5

        <P>In this paper, a novel approach for joint power control and user scheduling is proposed for optimizing energy efficiency (EE), in terms of bits per unit energy, in ultra dense small cell networks (UDNs). Due to severe coupling in interference, this problem is formulated as a dynamic stochastic game (DSG) between small cell base stations (SBSs). This game enables capturing the dynamics of both the queues and channel states of the system. To solve this game, assuming a large homogeneous UDN deployment, the problem is cast as a mean-field game (MFG) in which the MFG equilibrium is analyzed with the aid of low-complexity tractable partial differential equations. Exploiting the stochastic nature of the problem, user scheduling is formulated as a stochastic optimization problem and solved using the drift plus penalty (DPP) approach in the framework of Lyapunov optimization. Remarkably, it is shown that by weaving notions from Lyapunov optimization and mean-field theory, the proposed solution yields an equilibrium control policy per SBS, which maximizes the network utility while ensuring users' quality-of-service. Simulation results show that the proposed approach achieves up to 70.7% gains in EE and 99.5% reductions in the network's outage probabilities compared to a baseline model, which focuses on improving EE while attempting to satisfy the users' instantaneous quality-of-service requirements.</P>

      • SCOPUSKCI등재

        Future Prospects and Health Benefits of Functional Ingredients from Marine Bio-resources: A review

        Samarakoon, Kalpa W.,Elvitigala, Don Anushka Sandaruwan,Lakmal, H.H. Chaminda,Kim, Young-Mog,Jeon, You-Jin The Korean Society of Fisheries and Aquatic Scienc 2014 Fisheries and Aquatic Sciences Vol.17 No.3

        The marine ecosystem represents a vast and dynamic array of bio-resources attributed with its huge diversity and considered as potential untapped reservoirs for the development of functional foods for future health markets. Basically, marine microorganisms, sponges, algae, invertebrates such as crustaceans and mollusks along with marine fish species can be considered as marine bio-resources, which can be utilized to obtain different health benefits for humans, directly or after processing. Most of the bio-molecular components, such as lipids and proteins from these marine bio-resources, which can be extracted in large scale using the modern and advanced biotechnological approaches, are suitable drug candidates for the pharmaceutical industry as well as functional food ingredients for the food industry. Moreover, the furtherance of high throughput molecular biological techniques has already been incorporated with identification, mining and extraction of molecular components from marine bio-resources. In this review, potential marine bio-resources with respect to their extractable bio-molecules were described in details, while explaining the present and prospective methods of identification and extraction, which are integrated with advanced techniques in modern biotechnology. In addition, this provides an overview of future trends in marine biotechnology.

      • SCOPUSKCI등재

        The Growth, Innate Immunity and Protection against H<sub>2</sub>O<sub>2</sub>-Induced Oxidative Damage of a Chitosan-Coated Diet in the Olive Flounder Paralichthys olivaceus

        Samarakoon, Kalpa W.,Cha, Seon-Heui,Lee, Ji-Hyeok,Jeon, You-Jin The Korean Society of Fisheries and Aquatic Scienc 2013 Fisheries and Aquatic Sciences Vol.16 No.3

        We demonstrate enhanced growth, innate immunity and protection against hydrogen peroxide ($H_2O_2$)-induced protein oxidation and cellular DNA damage in olive flounder Paralichthys olivaceus fed a chitosan-coated moist pallet (MP) diet. A chitosan-based biopolymer coated MP as the experimental diet and a non-coated MP (control) was fed to olive flounder fish. Growth, including the average weight gain (g/fish), weight gain (%) and feed intake (g) of the fish group fed a chitosan-coated MP diet increased significantly. The survival rate was reported as 100% throughout the experimental period. Immunological parameters indicated higher mucus lysozyme activity and significantly higher fish skin mucus total protein content was observed in fish fed the chitosan-coated MP diet compared to the control. A blood plasma analysis revealed attenuation of cellular DNA and protein oxidative damage caused by $H_2O_2$-induced oxidative stress in the fish fed the chitosan-coated MP diet compared to the control group. Moreover, blood serum biochemical analysis revealed health-promoting effects, including significantly higher hemoglobin and total cholesterol levels in the fish fed the chitosan-coated MP diet compared to the control group. In conclusion, growth, innate immunity and protection against oxidative stresses were improved by feeding of the chitosan-coated MP diet to olive flounder reared in aquaculture.

      • Dynamic Clustering and <small>on</small>/<small>off</small> Strategies for Wireless Small Cell Networks

        Samarakoon, Sumudu,Bennis, Mehdi,Saad, Walid,Latva-aho, Matti IEEE 2016 IEEE TRANSACTIONS ON WIRELESS COMMUNICATIONS Vol.15 No.3

        <P>In this paper, a novel cluster-based approach for maximizing the energy efficiency of wireless small cell networks is proposed. A dynamic mechanism is proposed to locally group coupled small cell base stations (SBSs) into clusters based on location and traffic load. Within each formed cluster, SBSs coordinate their transmission parameters to minimize a cost function, which captures the tradeoffs between energy efficiency and flow level performance, while satisfying their users' quality-of-service requirements. Due to the lack of intercluster communications, clusters compete with one another to improve the overall network's energy efficiency. This intercluster competition is formulated as a noncooperative game between clusters that seek to minimize their respective cost functions. To solve this game, a distributed learning algorithm is proposed using which clusters autonomously choose their optimal transmission strategies based on local information. It is shown that the proposed algorithm converges to a stationary mixed-strategy distribution, which constitutes an epsilon-coarse correlated equilibrium for the studied game. Simulation results show that the proposed approach yields significant performance gains reaching up to 36% of reduced energy expenditures and upto 41% of reduced fractional transfer time compared to conventional approaches.</P>

      • SCIESCOPUSKCI등재

        In vitro studies of anti-inflammatory and anticancer activities of organic solvent extracts from cultured marine microalgae

        Samarakoon, Kalpa W.,Ko, Ju-Young,Shah, Md. Mahfuzur Rahman,Lee, Ji-Hyeok,Kang, Min-Cheol,Kwon, O-Nam,Lee, Joon-Baek,Jeon, You-Jin The Korean Society of Phycology 2013 ALGAE Vol.28 No.1

        Marine microalgae are a promising source of organisms that can be cultured and targeted to isolate the broad spectrum of functional metabolites. In this study, two species of cyanobacteria, Chlorella ovalis Butcher and Nannchloropsis oculata Droop, one species of bacillariophyta, Phaeoductylum tricornutum Bohlin, and one species of Dinophyceae, Amphidinium carterae (Hulburt) were cultured and biomasses used to evaluate the proximate comical compositions. Among the determined proximate chemical compositions of the cultured marine microalgae, the highest content of crude proteins and lipids were exhibited in P. tricornutum and A. carterae, respectively. Solvent-solvent partition chromatography was subjected to fractionate each of the cultured species and separated n-hexane, chloroform, ethyl acetate, and aqueous fractions. Nitric oxide production inhibitory level (%) and cytotoxicity effect on lipo-polysaccharide-induced RAW 264.7 macrophages were performed to determine the anti-inflammatory activity. N. oculata hexane and chloroform fractions showed significantly the strongest anti-inflammatory activity at $6.25{\mu}g\;mL^{-1}$ concentration. The cancer cell growth inhibition (%) was determined on three different cell lines including HL-60 (a human promyelocytic leukemia cell line), A549 (a human lung carcinoma cell line), and B16F10 (a mouse melanoma cell line), respectively. Among the extracts, C. ovalis ethyl acetate and A. carterae chloroform fractions suppressed the growth of HL-60 cells significantly at 25 and $50{\mu}g\;mL^{-1}$ concentrations. Thus, the cultured marine microalgae solvent extracts may have potentiality to isolate pharmacologically active metabolites further using advance chromatographic steps. Hence, the cultured marine microalgae can be described as a good candidate for the future therapeutic uses.

      • KCI등재

        Synthesis of SiAlON Ceramics with Novel Magnetic Properties

        B. Samarakoon Bandara Karunara,고재웅,박영조,김해두 한국세라믹학회 2009 한국세라믹학회지 Vol.46 No.5

        This paper presents a study on the magnetic behaviour of selected doped SiAlONs with various compositions including Y, Yb, Sm, Gd, and Er. The resulting crystalline phases were confirmed by X-ray diffraction. The magnetic hysteresis data for the samples were collected at room temperature using a vibrating sample magnetometer. The study revealed that doped SiAlONs experience an appreciable level of magnetic hysteresis. Although the parameters corresponding to hysteresis loops in doped SiAlONs are less than those of common ferrites, their magnetic properties of SiAlONs may open up new potential areas of application as the host SiAlON ceramics have excellent structural properties.

      • KCI등재

        Antibacterial effect of citrus press-cakes dried by high speed and far-infrared radiation drying methods

        Kalpa Samarakoon,Mahinda Senevirathne,Won-Woo Lee,Young-Tae Kim,Jae-Il Kim,Myung-Cheol Oh,You-Jin Jeon 한국영양학회 2012 Nutrition Research and Practice Vol.6 No.3

        In this study, the antibacterial effect was evaluated to determine the benefits of high speed drying (HSD) and far-infrared radiation drying (FIR) compared to the freeze drying (FD) method. Citrus press-cakes (CPCs) are released as a by-product in the citrus processing industry. Previous studies have shown that the HSD and FIR drying methods are much more economical for drying time and mass drying than those of FD, even though FD is the most qualified drying method. The disk diffusion assay was conducted, and the minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) were determined with methanol extracts of the dried CPCs against 11 fish and five food-related pathogenic bacteria. The disk diffusion results indicated that the CPCs dried by HSD, FIR, and FD prevented growth of all tested bacteria almost identically. The MIC and MBC results showed a range from 0.5-8.0 mg/mL and 1.0-16.0 mg/mL respectively. Scanning electron microscopy indicated that the extracts changed the morphology of the bacteria cell wall, leading to destruction. These results suggest that CPCs dried by HSD and FIR showed strong antibacterial activity against pathogenic bacteria and are more useful drying methods than that of the classic FD method in CPCs utilization.

      • KCI등재

        In vitro studies of anti-inflammatory and anticancer activities of organic solvent extracts from cultured marine microalgae

        Kalpa W. Samarakoon,고주영,Md. Mahfuzur Rahman Shah,이지혁,강민철,남권오,이준백,전유진 한국조류학회I 2013 ALGAE Vol.28 No.1

        Marine microalgae are a promising source of organisms that can be cultured and targeted to isolate the broad spectrum of functional metabolites. In this study, two species of cyanobacteria, Chlorella ovalis Butcher and Nannchloropsis oculata Droop, one species of bacillariophyta, Phaeoductylum tricornutum Bohlin, and one species of Dinophyceae, Amphidinium carterae (Hulburt) were cultured and biomasses used to evaluate the proximate comical compositions. Among the determined proximate chemical compositions of the cultured marine microalgae, the highest content of crude proteins and lipids were exhibited in P. tricornutum and A. carterae, respectively. Solvent-solvent partition chromatography was subjected to fractionate each of the cultured species and separated n-hexane, chloroform, ethyl acetate, and aqueous fractions. Nitric oxide production inhibitory level (%) and cytotoxicity effect on lipo-polysaccharide-induced RAW 264.7 macrophages were performed to determine the anti-inflammatory activity. N. oculata hexane and chloroform fractions showed significantly the strongest anti-inflammatory activity at 6.25 μg mL-1 concentration. The cancer cell growth inhibition (%) was determined on three different cell lines including HL-60 (a human promyelocytic leukemia cell line), A549 (a human lung carcinoma cell line), and B16F10 (a mouse melanoma cell line), respectively. Among the extracts, C. ovalis ethyl acetate and A. carterae chloroform fractions suppressed the growth of HL-60 cells significantly at 25 and 50 μg mL-1 concentrations. Thus, the cultured marine microalgae solvent extracts may have potentiality to isolate pharmacologically active metabolites further using advance chromatographic steps. Hence, the cultured marine microalgae can be described as a good candidate for the future therapeutic uses.

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