運動選手의 身體構成과 體型 및 最大有酸素性 能力에 關한 縱斷的 硏究 : 蹴球選手를 中心으로 Emphasised on soccer Players

林相鶴,金豪敏,崔成根,韓泰龍 서울市立大學校 1989 論文集 Vol.23 No.-

This study attempts to find the change and the relationship of body composition somatotype and maximum aerobic power according to the age on the based of result of the survey performed to 69 subjects who attended in the K college, D high school, K middle school. The result were as follows : 1. The percent of fat of all the subjcets was lower than that of ordinary people. 2. Somatotype of subjects was higher mesomorph and lower endomorph. 3. Maximum oxygen uptake was increasing and maximum oxygen uptake per kilogram of body weight was decreasing according to growth. 4. Endomorph and maximum oxygen uptake was sure to have certain correlation.

Physical and Physiological Dormancy in Black Henbane (Hyoscyamus niger L.) Seeds

C¸lrak, Cu¨neyt,Kevserog˘lu, Kudret,Sagˇlam, Birsen 한국식물학회 2004 Journal of Plant Biology Vol.47 No.4

Aim of this study was to investigate the nature of dormancy in black henbane (Hyoscyamus niger) seeds which have low germination rate under normal laboratory conditions. To do this, before placing the seeds in Petri dishes, they were soaked in 5, 10 and 15 ㎎/L GA; 1, 2 and 3% H₂SO₄,15 ㎎/L GA + 1% H₂SO₄, 0.01 M KNO₃ solutions, tap water, 40, 50 and 60°C hot water for 30 min. The study was performed under both continuous illumination and darkness in growth chambers to evaluate the effect of light on germination rate. The results showed that H₂SO₄ and GA treatments were the most important factors affecting seed germination and their germination enhancing effects were more evident in darkness. The results also suggested that black henbane seeds exhibit double dormancy involving a hard seed coat and a partially dormant embryo and have a partial dark requirement to germinate.

Acute toxicity of aqueous extract of Ambrosia arborescens Mill. on biochemical and histopathological parameters in rats

Silva-Correa Carmen R.,Villarreal-La Torre Víctor E.,González-Siccha Anabel D.,Cruzado-Razco José L.,González-Blas María V.,Sagástegui-Guarniz William Antonio,Calderón-Peña Abhel A.,Aspajo-Villalaz Ci 한국독성학회 2022 Toxicological Research Vol.38 No.2

Medicinal plants play an important role in the management of various diseases, so their use has become widespread. However, in some cases the population uses plant species regardless of the toxicity they may possess. The objective of this study was to evaluate the acute toxicity of aqueous extract from the leaves of Ambrosia arborescens Mill. on the biochemical and histopathological parameters of albino Holtzman rats. To do this, the leaves of A. arborescens were collected in the province of Julcan, La Libertad Region—Peru. OECD (Organisation for Economic Cooperation and Development) guideline 423 was conducted, forming experimental groups of 10 animals each one (5 males and 5 females): Group I (Control), which received 2 mL physiological saline solution (SSF 0.9%), Groups II and III (A. arborescens-300 and A. arborescens-2000), which were given the aqueous extract leaves of A. arborescens in a single dose of 300 and 2000 mg/kg/day, respectively. On the 14th day of exposure, biochemical (creatinine, ALT and AST) and histopathological parameters were measured. The results show that the aqueous extract of A. arborescens at the dose of 2000 mg/kg produces an increase in biochemical parameters which is related to histopathological analysis of liver and renal tissue with mild congestion. The study concludes that the aqueous extract leaves of A. arborescens has a LD50 greater than 2000 mg/kg and produces mild congestion in kidneys and liver, but showed no significant toxicological changes in the other albino Holtzman rats organs.

Acquired noncaustic esophageal strictures in children

Sag, Elif,Bahadir, Aysenur,Imamoglu, Mustafa,Sag, Sefa,Reis, Gokce Pinar,Erduran, Erol,Cakir, Murat The Korean Pediatric Society 2020 Clinical and Experimental Pediatrics (CEP) Vol.63 No.11

Background: Esophageal stricture (ES) is an uncommon clinic entity in pediatrics that may be congenital or acquired in childhood. Acquired noncaustic ES is very rare, and clinical features of affected patients are unknown. Purpose: We aimed to evaluate the clinical findings, and outcomes of patients with acquired noncaustic ES to aid physicians in the early referral of patients to gastroenterologists. Methods: The medical data of patients with acquired noncaustic ES who were followed in our gastroenterology clinic between January 2009 and December 2019 were reviewed. Results: Acquired noncaustic ES was found in 12 of the 4,950 patients (0.24%) who underwent endoscopy during the study period. The main symptoms were dysphagia (58.3%), vomiting (33.3%), and chronic anemia (8.3%). Chronic malnutrition and underweight were found in 66.6% of the patients. The most common etiological factors were radiotherapy, peptic reflux, and achalasia (16.6%, each), while chemotherapy, squamous-cell carcinoma (SC) of the esophagus, eosinophilic esophagitis (EoE), esophageal web, epidermolysis bullosa, and esophageal diverticulum (8.2%, each) were the other etiological factors. Patients with EoE underwent endoscopic bougie dilation in addition to steroid use and elimination diet. Patients with epidermolysis bullosa and esophageal web underwent bougie dilation. Patients with peptic reflux-related ES were initially put on antireflux therapy, but during follow-up, one patient required esophageal replacement with colonic interposition. Patients with radiotherapy-related ES recovered with medical therapy. The patient with initially underwent surgical gastrostomy and tumoral mass excision. The patient then received chemotherapy and radiotherapy and underwent jejunal interposition. Patients with achalasia underwent surgical esophagomyotomy. Conclusion: The presence of solid dysphagia, malnutrition, and an associated disease may alert physicians to the presence of ES.

Recent Trends in the Biosorption of Heavy Metals: A Review

Sag, Yesim,Kutsal, Tulin The Korean Society for Biotechnology and Bioengine 2001 Biotechnology and Bioprocess Engineering Vol.6 No.6

Considerable attention has been focused in recent years upon the field of biosorption for the removal of metal ions from aqeous effluents. Compared to other technologies, the advan-tages of biosortption are the high purity of the treated waste water and the cheap raw material. Really, the first major challenge for the biosorption field is to select the most promising types of biomass. Abundant biomass types either generated as a waste by-product of large-scale industrial fermentations particularly fungi or certain metal-binding seaweeds have gained importance in re-cent years due to their natural occurrence, low cost and, of course good performance in metal biosorption. Industrial solutions commonly contain multimetal systems or several organic and in organic substances that form complexes with metals at relatively high stability forming a very complex environment. When several components are present, interference and competition phe-nomena for sorption sites occur and lead to a more complex mathematical formulation of the process. The most optimal configuration for continuous flow-biosorption seems to the packed-bed column which gets gradually from the feed to the solution exit end. Owing to the com-petitive ion exchange taking place in the column, one or more of the metals present even at trace levels may overshot the acceptable limit in the column effluent before the breakthrough point of the trargeted metal. Occurrence of 'overshoot's and impact on havey metal removal has not been analyzed enough. New trends in biosorption are discussed in this review.

A Rare Cause of Recurrent Acute Pancreatitis in a Child: Isovaleric Acidemia with Novel Mutation

Sag, Elif,Cebi, Alper Han,Kaya, Gulay,Karaguzel, Gulay,Cakir, Murat The Korean Society of Pediatric Gastroenterology 2017 Pediatric gastroenterology, hepatology & nutrition Vol.20 No.1

Recurrent acute pancreatic attacks is a rare clinical condition (2-5% of all acute pancreatis) in children and is mainly idiopathic in most cases. Sometimes it may be associated with congenital anomalies, metabolic diseases or hereditary conditions. Isovaleric acidemia (IVA) is a rare autosomal recessive amino acid metabolism disorder associated with isovaleryl coenzyme A dehydrogenase deficiency presenting the clinical findings such metabolic acidosis with increased anion gap, hyperammonemia, ketonemia, hypoglycemia, "the odor of sweaty feet," abdominal pain, vomiting, feeding intolerance, shock and coma. Recurrent acute pancreatitis associated with IVA have been rarely reported. Herein; we report a child who admitted with recurrent acute pancreatic attacks and had the final diagnosis of IVA. Mutation analysis revealed a novel homozygous mutation of (p.E117K [c.349G>A]) in the IVA gene. Organic acidemias must kept in mind in the differential diagnosis of recurrent acute pancreatic attacks in children.

MMP2 Gene-735 C/T and MMP9 gene -1562 C/T Polymorphisms in JAK2V617F Positive Myeloproliferative Disorders

Sag, Sebnem Ozemri,Gorukmez, Ozlem,Ture, Mehmet,Gorukmez, Orhan,Topak, Ali,Sahinturk, Serdar,Ocakoglu, Gokhan,Gulten, Tuna,Ali, Ridvan,Yakut, Tahsin Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.2

Background: Myeloproliferative disorders (MPDs) are clonal hematologic malignancies originating at the level of the pluripotent hematopoietic stem cell. Matrix metalloproteases (MMPs) are proteolytic enzymes that contribute to all stages of malignancy progression. Genetic variants in the MMP genes may influence the biological function of these enzymes and change their role in carcinogenesis and progression. To our knowledge, this is the first investigation of associations between the -735 C/T and -1562 C/T polymorphisms in the MMP2 and MMP9 genes, respectively, and the risk of essential thrombocytosis (ET), and polycythemia vera (PV). Materials and Methods: The case-control study included JAK2V617F mutation positive 102 ET and PV patients and 111 controls. Polymorphisms were determined by using polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP) and electrophoresis. Results: No statistically significant differences were detected between patient (ET+PV) and control groups regarding genotype distribution for MMP2 gene-735 C/T and MMP9 gene -1562 C/T polymorphisms and C/T allele frequency (p>0.050). Statistically borderline significance was observed between PV and control groups regarding genotype distribution for the MMP9 gene -1562 C/T polymorphism (p=0.050, OR=2.26, 95%Cl=0.99-5.16). Conclusions: Consequently this study supported that CC genotype of MMP9 gene -1562 C/T polymorphism may be related with PV even if with borderline significance.

Endoscopic Findings of Children with Familial Mediterranean Fever

Sag, Elif,Demir, Ferhat,Saygin, Ismail,Kalyoncu, Mukaddes,Cakir, Murat The Korean Society of Pediatric Gastroenterology 2018 Pediatric gastroenterology, hepatology & nutrition Vol.21 No.4

Purpose: Familial Mediterranean fever (FMF) is an auto inflammatory disease characterized by periodic fever, synovitis and serositis. Patients may be admitted to gastroenterology units due to gastrointestinal symptoms. In this study; we aimed to analyze endoscopic findings and diagnostic utility of endoscopic procedure in children with FMF. Methods: Patient with FMF that was performed endoscopy for the gastrointestinal symptoms were included to the study (39 of 164 patients, 53 procedure). A control group was randomly designed as age and gender matched four endoscopic procedures per one endoscopic procedure of patients with FMF (n=212). Results: No different was found between the patients and control group in esophagogastroscopy findings. However, the diagnosis of gastrointestinal pathology was made by esophagogastroscopy in 46.2% patients. Colonoscopic examination revealed that the frequency of inflammatory bowel disease (IBD) was higher in undiagnosed patients compared to both the control group (50.0% vs. 6.9%, p<0.05, odds ratio [OR]:13.4 and 95% confidence inteval [95% CI]: 2.1-84.3) and the patients under colchicine treatment (50.0% vs. 8.3%, p<0.05, OR: 11 and 95% CI: 0.8-147.8). Colonoscopic procedure that was made after the diagnosis was found to provide contribution by 16.7% in determining the etiology of the additional symptoms. Conclusion: Patients with FMF may be admitted to pediatric gastroenterology outpatient clinic prior to diagnosis or during the follow-up period. The frequency of IBD is high in undiagnosed patients with FMF. Endoscopic procedures may be helpful in these patients for the diagnosis accompanying mucosal lesions.

Accessory Hepatic Lobe: A Rare Cause of Prehepatic Portal Hypertension in a Child

Sag, Elif,Cansu, Aysegul,Imamoglu, Mustafa,Cakir, Murat The Korean Society of Pediatric Gastroenterology 2018 Pediatric gastroenterology, hepatology & nutrition Vol.21 No.4

Accessory hepatic lobe is noted as and considered a rare disease in children. It can manifest with various symptoms and complications depending on the location, volume, type and position of the disease as presented on a child. The patient presented as a 14-month-old girl who was seen with a notable hepatosplenomegaly and portal hypertension. A diagnosis was made after taking an extensive medical history, observation and radiological examinations. The formal diagnosis was a prehepatic portal hypertension associated with accessory hepatic lobe.

齒系囊腫으로 誤診된 琺瑯芽細胞腫의 治驗例

SAG CHULL LEE(李相喆),PAN SIK KIM(金判植),SEON YUL YOO(柳善烈),IN CHOI(崔仁) 대한구강악안면외과학회 1979 대한구강악안면외과학회지 Vol.5 No.1

Ameloblastoma is one of the typical odontogenic tumor which was occasionally confused to dentigerous cyst. In this case, roentgenogram revealed a large monolocular radiolucent lesion from the left lower first molar region to the notch of ram us with White outline and contained tooth crown. The left lower second molar was extracted and pus discharged from the socket, we diagnosed as DENTIGEROUS CYST WITH SECONDARY INFECTION. Under the general anesthesia, the cystic sac was thoroughly removed and routinely, irrigation and vaseline gauze packing were done. As a result, post operative biopsy showed as AMELOBLASTOMA. After 6 months operation, authors can observe the homogenously new bone formation and there are no recurrency until now.