개에서 발생한 기관 허탈의 진단과 관리

이새미,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

A 11-year-old Yorkshire terrier anesthetized for computed tomography. The dog showed cyanosis and syncope during postanesthetic recovery, therefore drug administrated parenterally. Goose-honking was noticed after full recovery. As a result of survey radiography and fluoroscopy, grade 4 tracheal collapse was diagnosed. Prescription for the dog was oral administration of hydrocodone 0.22 mg/kg. theophylline 20 mg/kg, prednisone 0.5 mg/kg, amoxicillin 22 mg/kg and chlorpheniramine 2 mg/kg twice a day for 3 days. A 10-year-old Pomeranian was diagnosed as grade 2 traceal collapse at the local animal hospital 2 years before being referred to the veterinary teaching hospital of Chungnam National University. On physical examination, goose-honking, coughing and intermittent open-mouth breathing. Tracheal narrowing was observed on survey einradiography and fluoroscopy. Oral administration of theophylline 13 mg/kg, enrofloxacin 5 mg/kg, chlropheniramine 0.5 mg/kg twice a day was prescribed for 2 weeks.

접착제와 와동형성의 차이에 따른 5급 복합레진 수복의 전향적 임상연구

이경욱,정세준,한영철,손호현,엄정문,오명환,조병훈 大韓齒科保存學會 2006 Restorative Dentistry & Endodontics Vol.31 No.4

본 연구의 목적은 복합레진을 이용한 비우식성 치경부 5급 병소 수복에 있어서, 3가지 다른 접착제를, 유지구를 부여한 치아와 부여하지 않은 치아에 적용하였을 때의 임상적인 효능의 차이를 비교하기 위함이다. 총 150개의 치아를 각각 25개씩 6개의 군으로 나누었다. A군 Scotchbond Multi-Purpose (SBMP, 3M ESPE, St, Paul, MN, USA, 4세대 접착제)를 사용하고 유지구를 부여하지 않음. B군: SBMP를 사용하고 유지구를 부여. C군: BC Plus (Vericom Co., Anyang, Gyeonggido, Korea, 5세대 접착제)를 사용하고 유지구를 부여하지 않음. D군: BC Plus를 사용하고 유지구를 부여. E군: Adper Prompt (3M ESPE, Seefeld, Germany, 6세대 접착제)를 사용하고 유지구를 부여하지 않음. F군: Adper Prompt를 사용하고 유지구를 부여. 모든 치아는 복합레진인 Denfil(Vericom Co., Anyang. Gyonggido. Korea)을 이용하여 충전하였다. 수복 직후와, 수복 6개월 후에 modified USPHS (United States Public Health Service) criteria에 따라 수복물을 임상적으로 평가하였다. 추가적으로 임상사진을 촬영하였으며, 에폭시 레진을 이용하여 복제한 후 주사전자현미경을 이용하여 이를 관찰하였다. 6개월 후 관찰 결과. alpha rating의 수가 각 실험군마다 동일하지는 않았지만, 통계적으로는 3가지의 접착제간에 유의할만한 차이는 없었고, 기계적인 유지구를 부여한 군과 부여하지 않은 군 간에도 유의할만한 차이는 없었다 (p > 0.05). 그러나 6개월의 관찰 기간은 일반적으로 기대되는 레진의 수명보다 짧기 때문에, 각 실험군 간의 차이를 알아보기 위해서는 추후 더 오랜 기간의 관찰이 요구된다. The purpose of this study is to evaluate prospectively the effect of different bonding systems and retention grooves on the clinical performance of resin restorations in non-carious cervical lesions (NCCLs). Thirty nine healthy adults who had at least 2 NCCLs in their promolar areas were included in this study. One hundred and fifty teeth were equally assigned to six groups; (A) Scotchbond Multi-Purpose (SBMP, 3M ESPE, St, Paul, MN, USA, 4th generation bonding system) without retention grooves; (B) SBMP with retention grooves: (C) BC Plus (Vericom Co., Anyang, Gyeonggido, Korea, 5th generation bonding system) without retention grooves; (D) BC Plus with retention grooves; (E) Adper Prompt (3M ESPE, Seefeld, Germany, 6th generation bonding system) without retention grooves: (F) Adper Prompt with retention grooves. All cavities were filled with a hybrid composite resin, Denfil (Vericom Co., Anyang, Gyeonggido, korea) by one operator. Restorations were evaluated at baseline and at 6-month recall, according to the modified USPHS (United states Public Health Service) criteria, Additionally, clinical photographs were taken and epoxy resin replicas were made for SEM evaluation. At 6-month recall, there were some differences in the number of alpha ratings among the experimental groups. But, despite the differences in the number of alpah ratings, there was no significant difference among the 3 adhesive systems (p > 0.05). There was also no significant difference between the groups with or without mechanical retention (p > 0.05). Follow-ups for longer periods than 6 months are needed to verify the clinical performance of different bonding systems and retention grooves. 〔J Kor Acad Cons Dent 31(4):300-311, 2006〕

계장화충격시험에 의한 복합조직강의 파괴인성에 관한 연구

오세욱,유재환,박원조,이경봉 동아대학교 공과대학 부설 한국자원개발연구소 1989 硏究報告 Vol.13 No.1

The dynamic fracture toughness (K_(Id)) is measured using the precracked standard Charpy specimen with an instrumented impact machine. The value of K_(Id) is determined as a function of yield strength and microstructure, and correlations are established between K_(Id) and both energy of initial fracture and total energy of fracture. Since the K_(Id) values of the precracted impact specimens are in accordance with their theoretical ones, this test method is sufficiently practical.

불소화합물의 플라즈마 중합을 이용하여 제조한 복합막을 통한 혼합기체의 투과거동

오세중,구자경 선문대학교ㆍ중소기업기술지원연구소 2000 선문공대 연구/기술 논문집 Vol.5 No.1

수술중 수혈환자에 대한 임상적 고찰(Ⅲ)

최세진,서경덕,조희경 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

Over the Past several decades blood and blood components have been increasingly, recognized as medication rather than innocuous fluids used to replace modest blood lose at operation. But blood transfusions have the potential for many harmful side effects. This study was undertaken to evaluate transfusion accordings to department, sex, preoperative hemoglobin values, blood type, transfusion amounts and blood component therapy. Of a total 34.906 operative cases, 5,793 patients who recived a transfusion during operation were analyze statistically at the Department of anesthesiology, chungnam National University Hospital from January 1985 to September 1992. The results were as Follows : 1) The numbers of transfused patient among the 34,906 operative cases were 5,793 cases (16.57%). 2) The number of male transfused was greater than of female and third decade patients was the greatest incidence among the transfused patients. 3) Mostly hemoglobin value in preoperative state was maintained more than 10 mg/dl (85.75%). 4) The blood types of transfused blood were in the great order of A, B, O, AB type. 5) The percentage of one pint transfusion was gradually decreased and 2~5 pints transfusion was greatest percentage (60.11%). 6) As the amount of blood transfused was increased, the percentage of blood component therapy was increased, and mixed case PRC and FFP was the greatest incidence (46.02%).

Propofol이 정맥 마취 유도 및 유지시 심혈관계에 미치는 영향

최세진,박세린,조희경,김만수,임정혁 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

The cardiovascular response to anesthesia with the aqueous emulsion formulation of propofol was studied in healthy patient (ASA I or II; aged 20-61 years) premedicated with atropine 0.01mg/kg who underwent superficial minor surgery. Anesthesia was induced in all patient with propofol 2mg/kg - 2.5mg/kg immediately maintained by a continuous intravenous infusion of 6mg/kg/hr to supplement 50% nitrous oxide. We compared the cardiovascular changes of preinduction and post-induction. The results were as follows; 1) Heart Rates remained unchanged but increased in response to laryngoscopy and tracheal intubation from pre-laryngoscopy values and there were no significant changes. 2) Systolic and diastolic arterial pressure were decreased significantly at 1 minute after induction (p<0.01), 5 minutes after intubation (p<0.05), 10 minutes after intubation (p<0.001). Although the arterial pressure increased in response to tracheal intubaton and surgical stimuli, there were no significant changes.

통합형 취학 전 교육(Edu-care)의 운영 실태 고찰

나세경,엄정애 이화여자대학교 사범대학 교육과학연구소 2003 교육과학연구 Vol.34 No.3

Early childhood education industry in Korea is rapidly changing along with the changes in both social and individual life style. The demand for all-day program in early childhood education is gradually increasing because of the increase in nuclear family, double-income house, and higher standards of living. Therefore, Seoul Metropolitan Office of Education has executed the Edu-care program in Public Kindergarten since 2003 to meet this needs. This study was conducted to investigate the management conditions down to the Edu-care program in public kindergarten including general administration, facilities, nutrition, health, and safety as well as parent education and cooperation with community. For this study, the questionnaires were used and had been distributed to 13 teachers who work in public kindergarten running the Edu-care program, Completed questionnaires were received from 11 respondents and then gathered data were analyzed. The suggestions to improve the quality of Edu-care programs were made on the basis of the results. 본 연구의 목적은 질 높은 통합형 취학 전 교육 프로그램의 바람직한 방향을 모색하기 위한 기초 연구로서 현재 시범적으로 실시하고 있는 통합형 취학 전 교육 프로그램의 운영실태를 파악해 보는 것이다. 통합형 취학 전 교육 프로그램을 시범적으로 실시하고 있는 11개소의 공립유치원 원감 또는 부장 교사를 대상으로 하여 연구자가 개발한 질문지를 사용하여 조사연구한 결과, 기존 종일제와 비교해 보았을 때 운영시간, 전담교사 확보, 학급당 인원수, 시설·설비 등에 있어서 많이 개선되었다. 그러나 대부분이 초등학교에 병설되어있기 때문에 시설·설비를 위한 공간이 부족하였으며, 건강과 안전 관리 측면에서 교사들이 여러 가지로 배려하고 있었으나 전문적이고 체계적인 대처를 위한 배려는 아직 미흡한 실정이었다. 하지만 통합형 취학 전 교육은 시대적 요구에 의해 시행된 것이므로 미흡한 부분들을 보완하고 많은 유아들에게 혜택이 돌아갈 수 있도록 지속적인 정부차원의 행정적·재정적 지원이 필요하다.

연쇄구균의 세포벽 단백질이 L929 세포의 미세구조 변화에 미치는 영향에 관한 연구

임미경,오세홍 大韓齒科保存學會 1995 Restorative Dentistry & Endodontics Vol.20 No.2

자가 면역성 간염에서 자가항체의 발현 양상과 스테로이드 치료의 효과

박기오,채경훈,허원석,강윤세,정재훈,김연수,문희석,이엄석,김선문,이병석,김남재,이헌영 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

목적 : 최근 8년간 본원에서 경험한 자기면역성 간염의 혈액학적 특징과 스테로이드의 치료효과를 알아보고자 본 연구를 시행하였다. 방법 : 1996년 이후부터 2002년까지 충남대학교 병원에서 1999년 International Autoimmune Hepatitis Group(LAHG)에서 제시한 수정 진단 기준안에 의거하여 총 진단점수가 probable 이상에 해당하는 환자들을 대상으로 임상적 특징, 검사실 및 조직 소견과 스테로이드와 azathioprine의 치료 효과를 후향적으로 조사하였다. 결과 : 9예의 환자들은 여성이 78%, 40대가 많았고, 급성 발병이 33.3%, 피로감, 식욕부진 및 황달 등이 나타났으며, 항핵항체가 55.6%에서 그리고 항평활근 항체가 77.8%에서 양성이었고, 동반 질환은 류마치스 관절염이 2예, 특발성 혈소판 감소증 1예, Henoch-Sch nlein 자반증 및 그레브스병이 각각 1예 씩이었다. 7예에 대해서 스테로이드와 azathioprine으로 치료하여 생화학적 임상적 완해가 이루어져서 유효한 치료 결과를 얻었다. 결론 : 자가면역성 간염은 우리 나라에서 원인을 찾을 수 없는 만성 간질환의 경우, 특히 중년여성에서 다른 자가면역성 질환이 동반되었을 때 자가면역성 간염을 의심하여 자가항체 선별검사를 시행해 보아야 할 것으로 생각된다. 향후 다기관 연구를 통하여 좀 더 많은 증례를 모으고 전향적인 연구를 시행하여야 할 필요가 있다. Although autoimmune hepatitis(AIH) is common in western contries, some studties have been reported in Korea. The aim of the study was to analyze the clinical and histological features and expression pattern of the autoantibody and to examine clinical course of AIH in Korea. For 9 patients diagnosed as having AIH in our hospital since 1996, we reviewed medical records and analyzed clinical and laboratory findings retrospectively. They had a probable or definite AIH according to the revised criteria of International AIH group. The mean age was 42.7(21∼68)years and 7(77.8%) were female. Three of them(33.3%) showed acute hepatitis and five of them showed cirrhosis. Fatigue and anorexia were the most frequently complained symptoms(55.6%). Four patients(44.4%) were accompanied with other autoimmune diseases. Antinuclear antibody was detected in 5(55.6%) and anti-smooth muscle antibody was detected in 7(77.8%). Three patients showed focal picemeal necrosis and four showed periportal fibrosis. Among 7 patients who received immunosuppressive therapy, six patients(85.7%) showed initial response. and biochemical and serologic remission were achived in 5(71.4%) and 3(42.8%) patients, AIH seems to be partly responsible for chronic liver disease of unknown etiology in Korea. AIH should be suspected in female patients with unknown chronic liver disease of unknown etiolgy, especially accompanied with other autoimmune disease. The clinical characteristics of AIH may not be quite different from those of Western countries.

백서에서 자가 피부이식후 항T임파구 단일클론항체 분포에 관한 면역조직화학적 연구

朴晩圭,金慶助,任昌俊,高世勳 단국대학교 치의학연구소 1991 논문집 Vol.3 No.-

This article is intended to study histopathological and immunohistochemical response after autogenous full-thickness skin graft in rat. 12 male Sprague-Dawley rats were used as the experimental animals. A 1 cm×1 cm skin (0.7mm diameter) was taken on the right inguinal area of the rat. Another full-thickness skin graft (1cm × 1cm) was taken from the left inguinal area of the rat. And it was transplanted to the right inguinal area of the rat. The left side wound was closed directly. Light microscopic observation was made at the postoperative 1, 3, 8, 16 day, after the hematoxylin-Eosin staining of the 4u-thick paraffin embedded specimens and the immunohistochemical staining of the 10u-thick frozen specimens with mouse anti-rat monoclone antibodies and ABC staining kit. The results were as follows. 1. Electromicroscopic studies revealed interstitial tissue bleeding of transplanted autogenous skin. The response was severe in the 1 day group after operation, moderate in 3 day group, mild in 8 day group, and almost resolved in the 16 days group. 2. Electromicroscopic studies also revealed a mild monocyte response in the 3 day and 8 day groups. A histiocytic infiltrate was observed. There was a mild response in the 3 day group and moderate response in the 8 day group. 3. Immunohistochemically studies revealed a few pan T cells in the 1 day group, mild appearance of pan T cells and cyototoxic T cells in the 3 day group, a moderate infiltrate of pan T cells and helper T cells in the 8 day group, and total resolution of pan T cells in the 16 day group. 4. According to these finding, a strong inflammatory response was observed around transplanted autogenous skin in the 3 & 8 day groups. In the 16 day group this response had resolved histopathologically and immunohistologically.