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        論文(론문) : 조선의 名醫 유이태(劉以泰,劉爾泰) 연구

        유철호 ( Chulho Yoo ),유원준 ( Won Jun Yoo ),차웅석 ( Wungseok Cha ),홍세영 ( Sae Young Hong ),김남일58 ( Nam Il Kim ) 대한한의학원전학회(구 대한원전의사학회) 2013 대한한의학원전학회지 Vol.26 No.4

        Objective: Two famous medical doctors, Yoo Itae(以泰, 爾泰) and Riu Euitae(義泰), have been well known in academic world and public in Sancheong-gun. Yoo Itae is the progenitor of Majinhak which is the therapy for measles, he wrote a “Majinpyun” as the first book of therapy for measles in Chosun. Riu Euitae, meanwhile, is a fictional medical doctor and a teacher of Heo Jun who became real without confirmation of historical truths by Roh Jeongwoo who heard about a name, Yoo Itae. Roh`s assertion was quoted in the report of literatures, papers, novel, and telecast without verification. His assertion is exposed in novel and media and it has seriously distorted the history. The purpose of this study is to rectify the historical distortion. Methods: Various references study was performed. Confirmed a family tree, birth and death year, birthplace, sepulture, words on a tombstone, writing, collections of works anthology and the existence of keepsake. Investigated records of royal family, Sancheong-gun papers, Sancheong Hyanggyo papers, Dongyuhagan, Chosun Hanryuseungram and the record of Sawoo Munjip(anthology). Analyzed Roh Jungwoo`s conversation that tells Riu Euitae is a teacher of Heo Jun and contents of an encyclopedia. Listened to testimony of descendants and assertions of historian in rural area. Verified voice recording on books taken from at birthplace and the space of activity. Results: Yoo Itae is well shown in various records and medical writing books, whereas Riu Euitae does not. Riu Euitae is not a real person in the history. Roh Jeongwoo who asserts Riu Euitae is a teacher of Heo Jun admits his mistake. But, the encyclopedia record describing Riu Euitae is a teacher of Heo Jun, government official at Sancheong district office, historians in rural area, historians in rural area who made a family shrine, gravestone, a statue, memorial, historic site of Riu Euitae on Jinju Rui could not suggest any evidences for the existence of Riu Euitae and for record Riu Euitae is a teacher of Heo Jun. Conclusion : Riu Euitae is neither a real person in the history nor a teacher of Heo Jun. Riu Euitae came from pronunciation confusion between ‘I’ and ‘Eui’ in Kyungsang province. Riu Euitae is Yoo Itae on Geochang Yoo who was a medical doctor of King, Sukjeong and wrote medical books including <Majinpyun>, <Silheomdanbang>, <Inseomungyunrog>.

      • 개에서 발생한 기관 허탈의 진단과 관리

        이새미,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        A 11-year-old Yorkshire terrier anesthetized for computed tomography. The dog showed cyanosis and syncope during postanesthetic recovery, therefore drug administrated parenterally. Goose-honking was noticed after full recovery. As a result of survey radiography and fluoroscopy, grade 4 tracheal collapse was diagnosed. Prescription for the dog was oral administration of hydrocodone 0.22 mg/kg. theophylline 20 mg/kg, prednisone 0.5 mg/kg, amoxicillin 22 mg/kg and chlorpheniramine 2 mg/kg twice a day for 3 days. A 10-year-old Pomeranian was diagnosed as grade 2 traceal collapse at the local animal hospital 2 years before being referred to the veterinary teaching hospital of Chungnam National University. On physical examination, goose-honking, coughing and intermittent open-mouth breathing. Tracheal narrowing was observed on survey einradiography and fluoroscopy. Oral administration of theophylline 13 mg/kg, enrofloxacin 5 mg/kg, chlropheniramine 0.5 mg/kg twice a day was prescribed for 2 weeks.

      • SCOPUSKCI등재
      • 알루미나이징 表面處理한 構造用鋼의 彼勞强度 및 破壞擧動에 관한 硏究

        吳世旭,朴春根,全泰玉,全哲昊,周原植,李圭用 東亞大學校 大學院 1978 大學院論文集 Vol.2 No.-

        Aluminizing-treated structural steel is excellent in high temperature oxidation resistance, wear resistance and corrosion resistance. So, it has been widely used for the machine parts which have required such properties. However it is difficult to find out any study result of the notched influence on the aluminizing-treated materials and the second diffusion materials. In this investigation the low carbon steel plates with with V-notches were coated with aluminum and made into second diffusion. With these specimcns the bending fatigue strength and fatigue life were observed and also crack propagation of alloy layer was investigated. The results obtained are as follows: 1) On the smoothed specimens a fatigue limit of aluminizing material was lower than the one of raw material, but it was more increased than the one of heat treatment material, and the fatigue limit of second diffusion material was lowest. 2) On the V-notched specimens a fatigue limit of aluminizing material was higher with 44% increase ratio than the one of raw material and with 63% increase ratio than the one of heat treatment material, and the rate of increase became lower increase ratio in a fatigue limit comparing to aluminzing material, with no influence of notch radius. 3) According as the notch radius became smaller, the fatigue limit became. higher on the raw material, it was same on th aluminizing material and lowest on the second diffusion material. 4) Crack initiation period was 0.04% below of fatigue crack life and the full growth period of crack propagation at alloy layer was 0.1%. The crack propagation from alloy layer to matrix was 16% of the fatigue crack life. This means that the crack propagation rate at alloy layer was very fast but the crack delay at the boundary of both was so long. 5) Crack propagation grows through defects, inclusion, peeling and previous boundary.

      • 급성 단순하부요로감염증 치료에서 노르플록사신과 루플록사신의 임상효과 및 안전성

        김세웅,이지열,이승주,조용현,윤문수 대한화학요법학회 2000 대한화학요법학회지 Vol.18 No.1

        목적 : 루플록사신은 긴 반감기와 넓은 항균력을 가진 퀴놀론계 항생물질이다. 급성 단순하부요로감염 치료에 있어서의 루플록사신의 효과와 안전성을 평가하기 위하여 기존의 퀴놀론계 항생물질인 노르플록사신과 비교임상시험을 실시하였다. 방법 : 본 임상시험은 전향적, 무작위 방법으로 진행하였으며 1997년 8월부터 1999년 3월까지 가톨릭대학교 의과대학 부속 성모병원 비뇨기과에 내원한 급성 단순하부요로감염 환자 72명을 대상으로 하였다. 연속적 무작위 배정방법을 통하여 루플록사신군 36명과 노르플록사신군 36명이 루플록사신 400㎎을 단회 경구투여 받거나 노르플록사신 400㎎을 12시간 간격으로 3일간 6회 경구투여 받았다. 임상효과, 미생물학적 평가 및 부작용을 비교 관찰하였다. 결과 : 총 64명의 환자가 시험을 완료하여 평가가 가능하였고, 이 중 루플록사신군은 32명이었고, 노르플록사신군은 32명이었다. 증상의 치료 및 개선을 임상적 유효성이 있는 경우로 하였을 때, 루플록사신투여군은 32례중 32예(100%)에서, 노르플록사신투여군은 32례 중 31례(96.9%)에서 만족할 만한 결과를 얻었다. 미생물학적 평가에서 루플록사신투여군은 32례 중 29례(90.6%)에서, 노르플록사신투여군은 32례 중 28례(87.5%)에서 미생물학적 소실을 보였다. 미생물학적 재발은 루플록사신군과 노르플록사신군에서 각각 1례(3.1%)과 2례(6.3%)가 나타났고, 재감염은 각각 2례(6.3%)와 1례(3.1%)가 나타났다. 임상효과와 미생물학적 평가에서는 두 약제간의 통계학적 차이는 없었다. 약물역동학적 검사상 루플록사신은 노르플록사신에 비해 높은 MIC를 갖고 있지만 긴 반감기를 통해 소변내에서 높은 농도와 요 살균력을 유지함을 알 수 있었다. 부작용은 루플록사신투여군 34례 중 5례(14/7%)에서, 노르플록사신투여군 35례 중 1례(2.9%)에서 나타났으며, 대부분의 소화기계통의 이상반응 이었으며, 모두 경증으로 24시간 이내에 소실되었다. 루플록사신투여군 중 2례에서는 경증의 중추신경계의 이상반응이 관찰되었다. 결론 : 결론적으로 루플록사신은 급성 단순하부요로감염에 대하여 1회 투여만으로도 노르플록사신의 3일 투여법과 동등한 효과를 나타내는 유용한 약제라고 생각된다. Background : Rufloxacin is a broad-spectrum quinolone that exhibits a prolonged elimination half-life. The purpose of this study is to evaluate the efficacy and safety of a single dose of rufloxacin, campared with those of a norfloxacin standard treatment. Methods : This was a open. randomized. parallel-group, phase 11 clinical trial. A total of 72 women with acute lower urinary tract infections were included and randomly assigned to one of the treatment regimens: rufloxacin 400㎎ single dose, or norfloxacin 400㎎ b.i.d. for 3 days. Clinical and bacteriological assessments were performed twice at the third day and the seventh or tenth day after inclusion. Results : A total of 64 patients(32 and 32 patients in the rufloxacin and norfloxacin groups, respectively) were considered clinically and bacteriologically evaluable. Overall, a clinical response(recovery and improvement) was observed in 32 (100%) of 32 patients treated with rufloxacin and in 31 (96.95) of 32 patients with norfloxacin. The corresponding eradication rates of the primary pathogens were 90.6%(29/32) and 87.5%(28/32), respectively. The microbiological relapses between the seventh and tenth day were recorded in 1 patient(3.1%) and 2 patients(6.3%) in the rufloxacin and norfloxacin groups, respectively. The superinfections occurred in 2(6.3%) and 1(3.1%) patients, respectively. No statistically significant differences in the clinical or bacteriological outcome were observed between the treatment groups. The pharmacodynamic evaluation showed similar median urine bactericidal titers(UBT) for both treatment groups against initial isolates, despite a higher MIC of rufloxacin than that of norfloxacin. Five patients (14.7%) in the rufloxacin group and 2 patients (5.7%) in the norfloxacin group reported 9 and 4 adverse events, respectively, almost all of them being mild and lasting <24 h. Overall, gastrointestinal reactions were the most frequent adverse events reported. However, 2 patients treated with rufloxacin reported 3 central nervous system adverse events. Conclusion : This study suggests that single dose of rufloxacin treatment is effective and well tolerated as norfloxacin 3-day standard treatment in acute uncomplicated lower urinary tract infections.

      • HPLC를 이용한 Alnus속 식물에서의 diarylheptanoids의 정량분석

        정동욱,김준식,조수민,이연아,김광호,김세원,이민원 중앙대학교 약학연구소 1999 약학 논총 Vol.13 No.-

        Quantitative determination of diarylheptanoids (oregonin and hirsutanonol), which were characteristic components of Alnus spp. has been conducted by High Performance Liquid Chromatography. The HPLC analysis was carried out using an YMC J'sphere ODS-H80 column [150×4.6mm, S-4μm. 80A(particle)] and a combination of acetonitrile and H2O was used as mobile phase in gradient solvent system. The results showed differnce in the species (Alnus japonica, A hirsuta and A. hirsuta var. sibirica)

      • 민간경호원의 경호무도수련기간 및 승단현황에 관한 연구

        김규수,이성진,박준석,이세환 龍仁大學校 武道硏究所 2001 武道硏究所誌 Vol.12 No.1

        This study aims to find out what affects forming of perception and values of private security service guards regarding the security service martial arts and it puts its goal as investigation into perception and values of private security service guarding regarding the security service martial arts. To achieve the goal, objects of this study was set as private security service guards of private security service companies residing in Seoul, 2001. Among the security service guards, 200 individuals were selected and except 12 of them who answered questionaries insincerely, 118 security service guards was examined for the study. To analyze materials, significant level was set as a=0.5 and the SAS statics program was utilized. Comparative analysis was done according to each variables by one-way-ANOVA. Results of our study by the methods and the procedures are as follows. First, it was revealed that perceptions regarding security service martial arts according to ages of the guards show statistically significant differece. Security service guards who have 10 to 15 years of careers showed highest perception about the martial arts. Second, it was revealed that perceptions regarding the security service guards' values according to careers of them show statistically significant difference. Security service guards who have 10 to 15 years of careers showed highest perception on the values of the martial arts. Third. it was revealed that perceptions regarding the security service martial arts according to kind of the martial arts don't show statistically significant difference. Fourth, it was revealed that perceptions regarding the security service guards' values according to kind of the martial arts don't show statistically significant difference. Fifth, it was revealed that perceptions regarding the security service martial arts according to practice term of martial arts don't show statistically significant difference. Sixth, it was revealed that perceptions regarding security service guards' values according to practice term of martial arts don't show statistically significant difference. Security service guards who have more than 10 years of careers gained high marks of perception on values of job, courage and loyalty. Seventh, it was revealed that perceptions regarding the security service martial arts according to present condition of their rank promotion don't show statistically significant difference. Eighth, it was revealed that perceptions of security agents' values according to present condition of rank promotion don't show statistically significant difference.

      • 점증적 최대운동이 항산화 효소의 혈중 농도에 미치는 영향

        강신범,이상우,김상권,서해근,김준모 東亞大學校附設스포츠科學硏究所 1999 스포츠科學硏究論文集 Vol.17 No.-

        The purpose of this study is to examine how exercise stimulus effects on the boold concentration of antioxidant enzymes. And then, the results of analysing the boold concentration of antioxidant enzymes before and after graded maximal exercise based on high school's 7 males, are as follows: 1. The blood concentration of SOD is found to have a significant increase before and after graded maximal exercise. 2. The blood concentration of CAT is found to have a significant increase before and after graded maximal exercise. 3. The blood concentration of CAT is found to have a significant change. As the above results, the severe exercise of short time is found to increase the blood concentration of SOD as well as CAT. And then, the blood concentration of GPX is found not to have a significant exchange. To examine the mechanism of the above results manifestly, it is considered that the deep study based on exercise style, duration time and exercise intensity, should be continued.

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