압박띠와 Lidocaine 전처치 및 Pentothal 전처치를 이용한 Propfol 정주통의 예방효과

옥시영,김순임,김선종 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Background: Pain on injection of propofol is a common problem, the cause of which remains unknown, We evaluated the effect of a tourniquet with intravenous lidocaine and pentothal pretreatments, to decrease the incidence and intensity of pain during intravenous propofol injection. Methods: One hundred fifty five patients scheduled for general anesthesia were randomly divided into three groups. Each patient received one of the pretreatment drugs via 18 G angiocatheter inserted in the antecubital fossa. Control group (CG) (n=31) recived 2 ml normal saline and lidocaine group (LG) (n=31) received 40 mg (2%, 2 ml) and pentothal group (PG) (n=31) received 50 mg (2.5%, 2 ml) and lidocaine tourniquet group (LTG) (n=31) received 40 m g(2%, 2ml) under tourniquest 1 minute inflated and pentothal tourniquet group(PTG) (n=31) received 50 mg (2.5%, 2 ml) under tourniquet 1 minute inflated followed intravenous injection of 2 mg/kg of propofol at a rate of 1 ml/sec. after 50 mg of proplfol were injected, patients were assessed for pain score. The severity of pain was classified as 0, 1, 2, 3 (none, mild, moderate, severe) by one observer. Results: The severity and incidence of pain were significantly reduced in lidocaine group and pentothal group compared with control group for intravenous injection of propofol (P<0.05). But effect of tourniquet is minimal. And the quantity and quality of analgesic effect of lidocaine and petothal on propofol iv injection is similar. Conclusions: Lidocaine 40 mg or pentothal 50 mg pretreatment to induction by propofol revealed a good analgesic effect for propofol injection pain. But effect of tourniquest is minimal.

Lidocaine과 Pentotal 전투여가 Propofol 정주 시 발생되는 혈관통에 미치는 영향

옥시영,김순임,김선종 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Background: Propofol is a good induction agent. But it has a disadvantage of pain on intravenous injection. Pretreatment of lidocaine or pentothal have been reported to reduce pain on injection. Thus we have evaluated the quantity and quality of analgesic effect of lidocaine and pentothal. Methods: Ninety three patients scheduled for general anesthesia were randomly divided into three groups. Each patient received one of the pretreatment drugs via 18 G angiocatheter inserted in the antecubital fossa. Control group (n=31) received 2 ml normal saline and lidocaine group (n=31) received 40 mg (2%, 2ml) and petothal group (n=31) received 50 mg (2.5%, 2 ml) followed intravenous injection of 2 mg/kg of propofol at a rate of 1 ml/sec.After 50 mg of propofol were injected, patients were assessed for pain score. The severity of pain was classified as 0,1, 2, 3 (none, mild, moderate, severe) by one observer. Results: The severity and incidence of pain were significantly reduced in lidocaine group and pentothal group compared with control group for intravenous injection of propofol (P<0.05). And the incidence of pain in lidocaine group and pentothal group is similar but severity of pain is more reduced in lidocaine group Conclusions: Lidocaine 40 mg or pentohal 50 mg pretreatment to induction by propofol revealed a good analgesic effect for propofol injection pain. And lidocaine is more effective for iv propofol injection pain.

2.5% Pentothal sodium 전처치가 Propofol 정주시 발생되는 통증에 미치는 효과

옥시영,김순임,김선종 순천향대학교 교수학습개발센터 2004 Journal of Soonchunhyang Medical Science Vol.10 No.3

Background: propofol has a high incidence of pain with intravenous injection, and many different methods have been used to minimize the incidence and severity of this pain. In this study, we have compared the effect of saline pretreatment with that of 2.5% pentothal 50 mg pretreatment of propofol injection pain. Methods: Sixty two patients scheduled for general anesthesia were randomly divided into two groups. each patient received one of the pretreatment drugs via 18 g angiocatheter inserted in the antecubital fossa. Control group (n=31)received 2 ml of 0.9% saline pretreatment, 2.5% pentothal group (n=31) received 50 mg of pentothal pretreatment followed intravenous injection of 2 mg/kg of propofol at a rate of 1 ml/sec. After 50 mg of propofol were injected, patients were assessed for pain score. The severity of pain was classified as 0, 1, 2, 3 (none, mild, moderate, severe) by one observer. Results: The severity of pain were significantly reduced in 2.5% pentothal group compared with ontrol group for intravenous injection fo propofol (p<0.05) but incidence is similar. Conclusions: 2.5% pentothal 2 ml (50 mg) pretreatment could significantly reduce the sever the severity of pain for intravenous injection of propofol.

韓方看護師의 役割에 대한 硏究

옥도훈,박찬국,신순식 한국한의학연구원 1999 한국한의학연구원논문집 Vol.5 No.1

The goal of this study is to review and define the role of nurses who are engaged in Korea Oriental treatments in oriental medical hospitals. We think this study can contribute to the development of "Korea Oriental medical science & nursing science" and "Public health care". A large portion of nurses's role in Korea Medicine(KOM. 한방/한의학) is assistance to doctors treatment. But besides of these role, we think there are many things that are riskless for nurses to do alone. But in present situation, few nurses in KOM, have enough knowledge to treat these medical treatments alone. So we believe this study will provide a way for nurses to participate more actively in KOM public health care. So we believe this study will provide a way for nurses that have been practiced in oriental medical health care. With the goal of this study, we checked all medical treatments that have been practiced in oriental medical hospitals, and classified these treatments with some groups. And we organized a inquiry. At this inquiry, we ask "What is th adequate role of nurses in Korea Oriental medical treatment? & What kind of treatment can nurses do?" We got 58 responses from nationwide 121 hospitals. From these response, more than half of them said nurses can do following medical treatment in the oriental medical hospital: 1. starting and ending part of following treatments; External treatments by instrument, by hydrotherapy, by herb, by suction, moxibustion, Manipulative therapies on soft structure, Living and mind-body therapies. 2. pulling out Acupuncture. 3. boiling herb, judgement on dosing temperature, assisting in dosing, 4. assisting Diet. 5. operating from Living and mind-body therapies. 6. leading Physical training However, these results are coming out from present situation. So, after well-oriented instructions for nurses, this study will be need to carry out again. From this study, we suggest a desirable curriculum for students who study "Korea Oriental Nursing Science". That is to say, at basic course students take 4 subject for 6 credit. And at as an expert course, it should be dividend into Clinical Nursing Specialist in KOM,. Self-care Nursing Specialist and take 17credits per each course.

문제발견 및 가설설정 능력 신장 과학영재교육프로그램 개발 : 멘델의 과학적 사고과정 적용

김순옥,김봉선,서혜애,김영민,박종석 韓國英才學會 2011 영재교육연구 Vol.21 No.4

본 연구는 역사적 발견을 이루어낸 과학자 가운데 멘델(Mendel, Gregor Johann, 1822-1884)의 과학적 사고과정을 활용하여 과학영재교육프로그램을 개발하고, 이 프로그램을 학습한 학생들의 문제발견 및 가설설정 능력의 변화를 측정하여, 프로그램의 효과성을 검증하는데 목적을 두었다. 이를 위해 먼저, 멘델이 유전법칙을 확립하는 과정에서 나타낸 과학적 사고과정을 분석하여 특징적 탐구요소를 추출하였다. 추출된 탐구요소 가운데 문제발견과 가설설정을 적용한 프로그램으로서 완두를 활용한 모의실험탐구중심의 과학영재교육프로그램을 개발하였다. 개발한 과학영재교육프로그램은 대학교 부설 과학영재교육원 소속 중학교 1, 2학년 학생 19명(남학생 11명, 여학생 8명)을 대상으로 적용되었다. 적용한 결과, 학생들은 문제발견 능력의 하위요소 융통성, 정교성, 독창성이 신장되었고, 가설설정 능력의 논리성도 신장되었다. 이에 개발된 과학영재교육프로그램은 중학교 과학영재로 선발된 학생들의 문제발견 및 가설 설정 능력을 향상시키는데 효과가 있는 것으로 고찰되었다. In the process of establishing the principle of genetics, Mendel discovered problems based on various observations. Mendel’s scientific thinking ability can be effective if this ability is embedded in gifted science education programs. The study aims to develop a science gifted education program utilizing Mendel’s scientific thinking ability shown in the principles of genetics and examine students’ changes in scientific thinking ability before and after the program implementation. For the program development, first, the characteristics of Mendel’s scientific thinking ability in the process of establishing the principle of genetics were investigated and extracted the major elements of inquiry. Second, the science gifted education programs was developed by applying the inquiry elements from the Mendel's Law. The program was implemented with 19 students of 7th, 8th graders who attend the science gifted education center affiliated with university during July 2011. The Mendel's scientific thinking ability was classified into induction, deduction, and integration. The elements of inquiry extracted from the Mendel’s scientific thinking include making observation, puzzling observation, proposing causal questions, generating hypothesis, drawing inference, designing experiment, gathering and analyzing data, drawing conclusions, and making generalization. With applying these elements, the program was developed with four phases: 1st - problem finding; 2nd - hypothesis generating; 3rd - hypothesis testing and 4th - problem solving. After implementation, students’ changes in scientific thinking ability were measured. The findings from the study are as follows: First, students’ abilities of problem finding is significantly (p<.05) increased. Second, students’ abilities of hypothesis generating is significantly (p<.05) increased.

베타락탐계 항생제 합성과 항균성

고옥현,강형룡,유진철,김경수,홍석순,김영수,황화영,하재천 조선대학교 약학연구소 1992 藥學硏究誌 Vol.14 No.1

7β[5-(Substituted) phenyl-2H-tetrazol-2-yl]acetamidocephalospranic acid, 7β-(5-Diphnenyl-methyl-2H-tetrazol-2-yl) acetamidocephalosporanic acid and 7β-[5-(Substituted)-4-phenyl-1.2.4-triazol2-yl]thioacetamidocephalosporanic acid were synthesized and tested in vitro antimicrobial activity. These compounds exhibited good antimicrobial activity against Gram-positive bacteria whereas most compounds showed decreased antimicrobial activity against Gram-negative bacteria

Azoloquinoxaline類의 간편한 合成에 관한 硏究 : 第1報

郭美玉,南順花,金恩慶,金眞姬,韓盛旭,李萬佶,朴義煥,金浩植 고신대학교 자연과학연구소 1993 고신대학교 자연과학연구소 논문집 Vol.3 No.-

The reaction of 2, 6-dichoroquinoxaline with m-chloroperbenzoic acid gave 2, 6-dichloroquinoxaline 4-oxide, whose reaction with sodium azide provided 7-chlorotetrazolo[1, 5-a]quinoxaline 5-oxide and not the isomeric azide. The structures of the synthesized compounds were confirmed on the basis of IR, ¹H-NMR, elemental analysis and mass spectral data.

세포질의 알카리화가 Fibroblast Monolayer에 미치는 Mitogenic Effect

文順玉 水原大學校 1989 論文集 Vol.7 No.-

Stimulation of ?? exchange by growth factors has been implicated as an event required for progression of cells from quiescence to a state competent for proliferation. To test this hypothesis, confluent monolayers of mouse and human fibroblasts, were treated with the carboxylic ionophore monensin which catalyzes ?? exchange at the plasma membrane. When ?? monensin is incubated with cells DNA synthesis is stimulated. Growth factors that stimulate ?? exchange also induce expression of two cellular proto-oncogenes, c-fos and c-myc. These gene products have been implicated as regulators of proliferation of mammalian cells. Transient exposure of quiescent Balb/c-3T3 cells to monensin stimulates expression of both c-fos and c-myc proto-oncogene. These data suggest that stimulation of ?? exchange regulates the level of mRNA decoding for c-fos and c-myc and provide a key stimulus for cell proliferation.

正岡子規의 短歌硏究 : 發展過程을 中心으로

孫順玉 中央大學校 人文科學硏究所 1988 人文學硏究 Vol.15 No.-

실과의 식생활 실습지도를 위한 이론적 고찰

조순옥 서울교육대학교 초등교육연구소 1999 한국초등교육 Vol.10 No.1

The purpose of this study is to investigate the teaching method for practices and experiments of Food &utrition course of practical arts education It is also designed for the curriculum, textbooks, teacher's guides of the practical arts education and the theoretical reference books The result of this study shows that each content of the Sixth Practical Arts Education Curriculum was chosen for the basic knowledge and techniques for works in domestic life and to prove the quality of life Its intellectual and technical level was decided concerning the mental and physical development of elementary school students Practices based on practical arts theories were important and affected on a real life But the practice hours in the Sixth Practical Art Education curriculum were too short to teach the whole contents Therefore the practice hours for each lesson must be secured In textbooks and the teacher's guides for the students from the third grade to sixth, cortains using vessels and kitchen utensils, methods for selection of meal and vessels, safe use of instruments, food hygiene, measuring and weighing food, scientifical cooking, understanding and improving Korean dietary cultural life Judging from the stage of mental and physical development of students, it is reasonable to teach the contents in food and nutrition section of the practical arts education course to the elementary school students from third grade to sixth The materials, instruments and time for the course can improve the students in their intellectual and technical activities, understanding each other, cooperative problem-solving spirit and manner, and diligence The evaluation of performance technique must be based on practical arts theories And it must be carried out before a practical lesson, during the process of a lesson and after finishing the course For the performance evaluation, the intellectual level and the technical movement and emotions need to be counted The instructing methods for the food and nutrition subject includes the following applying the lesson model focused on practice and experiences, catching hold of objectives and contents for subject, preparative conditions of students for lesson, promoting understanding of knowledge connected with materials, instruments and techniques for practice in conformation of subject, demonstration for the basic techniques and observing them, preparing standards for self evaluation in planning practical lesson, and carrying out the plan in learning of techniques