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Satoko Iwasawa,Tazuru Tsuboi,Makiko Nakano,Aya Hirata,Noriyuki Yoshioka,Satoko Suzuki,Shigeru Tanaka,Kazuyuki Omae 한국대기환경학회 2019 Asian Journal of Atmospheric Environment (AJAE) Vol.13 No.2
The island of Miyakejima in Japan is subject to ongoing emissions of volcanic gases, including high concentrations of sulfur dioxide (SO2). Annual health checkups on the island, therefore, include the examination of respiratory system parameters. Here, we aimed to investigate the relationship between SO2 exposure and fractional exhaled nitric oxide (FeNO) concentration among children who received health checkups from 2008 to 2014. The subjects were 83 and 31 second-year junior high school students aged 13-14 years who resided on Miyakejima island and an SO2-free reference island, respectively. SO2 concentration in the air was measured at 6 fixed-point monitoring stations. FeNO was examined according to the American Thoracic Society guideline and European Respiratory Society recommendations for standardized procedures. Average concentrations of SO2 on Miyakejima over a period of 3 months prior to each health checkup from 2008 to 2014 were 22.2, 20.6, 8.9, 10.5, 10.7, 4.4 and 8.0 ppb, respectively. Among the Miyakejima students, geometric mean (GM) FeNO concentrations measured at each health checkup from 2008 to 2014 were 28.2, 18.2, 23.6, 35.5, 36.9, 28.1, and 32.1 ppb. The GM FeNO concentration measured from all Miyakejima students across the study period was 28.3 ppb. No clear dose-response relationship was observed. The GM FeNO concentration among the students from the reference island was 27.7 ppb in 2017. No significant difference was observed between the two populations, even when the data was stratified by sex and sensitivity. There was no clear significant difference in GM of FeNO concentration between Miyakejima and control students, when the average concentration of SO2 over a period of 3 months was 22 ppb or less.
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MARKETING IN STEADY-STATE ECONOMY: EXPLORATORY CASE STUDY ON PIONEERING FIRMS
Satoko Suzuki,Akinori Iwamoto,Tomoko Kawakami 글로벌지식마케팅경영학회 2016 Global Marketing Conference Vol.2016 No.7
economic growth and revenue / profit expansion, we will end up with overconsumption and wastes, bringing serious damage to our planet (Kotler, 2015). He advocated the transition from the growth-oriented economy to the steady-state economy. This research explores marketing in such steady-state economy. Researchers have put efforts in developing theories in related concepts such as social marketing (e.g., Kotler & Zaltman, 1971) and corporate social responsibility (CSR; see Peloza & Shang, 2011 for a review). Inoue and Kent (2014) developed a conceptual framework that explains antecedents and consequences of corporate social marketing. However, their research, as well as those on CSR, has not addressed marketing in steady-state economy. Thus, we attempt to fill this research gap by developing propositions. We conducted multiple case studies (Eisenhardt, 1989; Yin 2014). Based on theoretical sampling, three firms were selected from different industries (food, alcohol, and furniture) with different technologies, located in different areas in Japan (Tokyo, Nagano, and Kagoshima). We collected primary and secondary data, and conducted interviews. In spite of the differences, the three firms run business similarly. First, they pursue a sustainable growth and not a rapid growth. Second, doing what is good for society is a part of their business goal and not CSR. Finally, they choose inefficiency than lowering the product quality.economy are developed: P1. Selling high quality products at profitable but reasonable price enhances firm’s credibility, which in turn improves the probability of firm’s long-term survival. P2. Limiting distribution channel allows firm to avoid price competition and set reasonable pricing, which in turn improves the probability of firm’s long-term survival. P3. Marketing mix of high quality product, reasonable pricing, and limited distribution channel generates positive word-of-mouth, allowing firm to save promotion costs. P4. Prosocial behavior in procurement increases the brand loyalty, which in turn improves the probability of firm’s long-term survival. P5. Portfolio of business-to-business and business-to-consumers businesses allows stable management and building strong brand. Further research is needed to develop these propositions into hypotheses and empirically test them with large samples. The authors hope that this research will be the first step for “steadiness-oriented marketing.”
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A SIGNATURE OF CHROMOSPHERIC ACTIVITY IN BROWN DWARFS: A RECENT RESULT FROM NIRLT MISSION PROGRAM
Satoko Sorahana,Takeru K. Suzuki,ISSEI YAMAMURA 한국천문학회 2017 天文學論叢 Vol.32 No.1
We present the latest results from the Mission Program NIRLT (PI: I.Yamamura), the near-infrared spectroscopy of brown dwarfs using the AKARI/IRC grism mode with the spectral resolution of $\sim120$. The near-infrared spectra in the wavelength range between 2.5 and 5.0~$\mu$m are especially important to study the brown dwarf atmospheres because of the presence of major molecular bands, including CH$_4$ at 3.3~$\mu$m, CO$_2$ at 4.2~$\mu$m, CO at 4.6 ~$\mu$m, and H$_2$O around 2.7~$\mu$m. We observed 27 sources, and obtained 16 good spectra. Our model fitting reveals deviations between theoretical model and observed spectra in this wavelength range, which may be attributed to the physical condition of the upper atmosphere. The deviations indicate additional heating, which we hypothesize to be due to chromospheric activity. We test this effect by modifying the brown dwarf atmosphere model to artificially increase the temperature of the upper atmosphere, and compare the revised model with observed spectra of early- to mid-L type objects with H$\alpha$ emission. We find that the chemical structure of the atmosphere changes dramatically, and the heating model spectra of early-type brown dwarfs can be considerably improved to match the observed spectra. Our result suggests that chromospheric activity is essential to understand early-type brown dwarf atmospheres.
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Satoko Abiko,Kengo Tashiro 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10
This paper presents attitude recovery control for a quad tilt rotor UAV. The quad tilt rotor UAV has ability of flying with cmpletely independent 3 DOF position and 3 DOF attitude control by changing the thrust directions. This type of UAV is expected to perform better response to the disturbance by virtue of the mechanism of changing the thrust directions compared to the conventional multi-rotor UAV. This paper proposes disturbance detection method using IMU sensor and develops attitude recovery control against impact disturbance. The numerical simulation and fundamental flight experiments were carried out to evaluate the effectiveness of the proposed method compared to the conventional PID control.
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Satoko Yamaguchi,Shunichi Yanai,Shotaro Nakamura,Keisuke Kawasaki,Makoto Eizuka,Noriyuki Uesugi,Tamotsu Sugai,Junji Umeno,Motohiro Esaki,Takayuki Matsumoto 대한장연구학회 2018 Intestinal Research Vol.16 No.3
Background/Aims: We recently identified recessive mutations in the solute carrier organic anion transporter family member 2A1 gene (SLCO2A1) as causative variants of chronic enteropathy associated with SLCO2A1 (CEAS). The aim of this study was to evaluate SLCO2A1 protein expression in the intestinal tissues of patients with CEAS, intestinal Behçet’s disease (BD), simple ulcer (SU), and Crohn’s disease (CD). Methods: Immunohistochemical staining using a polyclonal anti-SLCO2A1 antibody was performed on the resected intestinal specimens from 13 cases of CD, 9 cases of intestinal BD/SU, and 3 cases of CEAS. The extent of SLCO2A1 expression was determined by counting positively-staining vascular endothelial cells and scored as 0 (no cells), 1 (1%−30% cells), 2 (31%−60%), or 3 (>60%). The intensity of SLCO2A1 expression was scored either as 0 (negative), 1 (intermediate), or 2 (strong). The extent score and intensity score were summed for the final score of 0, 2, 3, 4, or 5. Results: SLCO2A1 protein expression was observed in 1 of 3 cases of CEAS (33%), all 13 cases of CD (100%), and all 9 cases of BD/SU (100%). The mean final expression scores of CEAS, CD, and BD/SU were 1.6 (range, 0−5), 4.8 (range, 4−5), and 4.3 (range, 4−5), respectively. The final expression score in CEAS was significantly lower than in CD (P=0.03). Conclusions: Immunohistochemical staining of the SLCO2A1 protein is considered useful to distinguish CEAS from other inflammatory bowel diseases.
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Satoko Sugie,Makoto Mitsugi 범태평양 응용언어학회 2014 범태평양응용언어학회지 Vol.18 No.2
The Information and Communication Technology (ICT) utilization in Chinese as a "second" foreign language has mainly been focused on Learning Management System (LMS), digital material development, and quantitative analysis of learners`` grammatical knowledge. There has been little research that has analyzed the effectiveness of cross-cultural distance learning by the mixed methods. In this study, Chinese classes were instructed with blended learning which has three phases such as classroom teaching, Web-Based Training, and Cross-Cultural Distance Learning. This practice was based on an instructional design and a motivational design. This study aimed to explore the outcome of learning and learners`` experiences with the mixed methods. A quantitative analysis shows that Japanese students have already had high motivation from the beginning, and that learners who are anxious about communication skills have gained confidence through the interaction practices. As a qualitative analysis result, learners failed to communicate with Chinese students and felt that they lacked vocabulary, but experienced the use of Chinese in authentic contexts through the synchronous face-to-face interaction. They also improved in aggressiveness and motivation for learning Chinese. They fixed words and sentences which were learned in the classroom in the process of talking to different partners. All participants enjoyed the rare chance of interaction between young native speakers, and formed a positive impression of them.
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Increased Expression and Role of Thymic Stromal Lymphopoietin in Nasal Polyposis
Satoko Kimura,Ruby Pawankar,Sachiko Mori,Manabu Nonaka,Satoru Masuno,Toshiaki Yagi,Kimihiro Okubo 대한천식알레르기학회 2011 Allergy, Asthma & Immunology Research Vol.3 No.3
Purpose: Nasal polyposis is a chronic inflammatory disease of the upper airways often associated with asthma and characterized by markedly increased numbers of eosinophils, Th2 type lymphocytes, fibroblasts, goblet cells and mast cells. Previous studies have shown elevated levels of thymic stromal lymphopoietin (TSLP) in atopic diseases like asthma, atopic dermatitis and mainly in animal models of allergic rhinitis (AR). Here, we investigated the expression of TSLP in nasal polyps from atopics and non-atopics in comparison with the nasal mucosa and its potential role in nasal polyposis. Methods: Messenger RNA expression for TSLP, thymus and activation-regulated chemokine (TARC) and macrophage derived chemokine (MDC) in nasal polyps and nasal mucosa of atopics and non-atopics was analyzed by real time PCR. Immunoreactivity for TSLP in nasal polyps and in the nasal mucosa of patients with AR and non-allergic rhinitis (NAR) was analyzed by immunohistochemistry. Eosinophil counts was analyzed by Wright-Giemsa staining and nasal polyp tissue IgE, by ELISA. Results: Messenger RNA expression for TSLP,TARC and MDC was markedly higher in nasal polyps as compared to the allergic nasal mucosa. Immunoreactivity for TSLP was detected in epithelial cells, endothelial cells, fibroblasts and inflammatory cells of the nasal mucosa and nasal polyps. The number of TSLP+ cells was significantly greater in the nasal mucosa of AR than NAR patients. The number of TSLP+ cells in nasal polyps from atopics was significantly greater than that of non-atopics and that in the allergic nasal mucosa. The number of TSLP+ cells correlated well with the number of eosinophils and the levels of IgE in nasal polyps. Conclusions: The high expression of TSLP in nasal polyps and its strong correlation to eosinophils and IgE suggest a potential role for TSLP in the pathogenesis of nasal polyps by regulating the Th2 type and eosinophilic inflammation.
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( Satoko Matsuzaki ),( Shinya Matsuzaki ),( Yutaka Ueda ),( Tomomi Egawa Takata ),( Kazuya Mimura ),( Takeshi Kanagawa ),( Eiichi Morii ),( Tadashi Kimura ) 대한산부인과학회 2014 Obstetrics & Gynecology Science Vol.57 No.5
Placenta previa presents a highest risk to pregnancy, and placenta accreta is the most serious. Placenta accreta requires cesarean delivery and often results in massive obstetric hemorrhage and higher maternal morbidity. Challenges associated with cesarean delivery techniques may contribute to increased maternal blood loss and morbidity rates. Several recent obstetric studies reported the usefulness of transverse uterine fundal incision for managing placenta accreta. We present a case of placenta percreta that was treated by a transverse fundal incision. We successfully avoided cutting through the placenta and helped decrease maternal blood loss. After delivery, the patient underwent a cesarean hysterectomy. Postoperative day 48, she experienced watery discharge and was diagnosed with vaginal fistula. We present our case and review the literature.
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