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        Predictive factors for flexible ureterorenoscopy requirement after rigid ureterorenoscopy in cases with renal pelvic stones sized 1 to 2 cm

        Evren Süer,Ömer Gülpinar,Cihat Özcan,Çağatay Göğüş,Seymur Kerimov,Mut Şafak 대한비뇨의학회 2015 Investigative and Clinical Urology Vol.56 No.2

        Purpose: To evaluate the outcomes of rigid ureterorenoscopy (URS) for renal pelvic stones (RPS) sized 1 to 2 cm and to determinethe predictive factors for the requirement for flexible URS (F-URS) when rigid URS fails. Materials and Methods: A total of 88 patients were included into the study. In 48 patients, the RPS were totally fragmented withrigid URS and F-URS was not required (group 1). In 40 patients, rigid URS was not able to access the renal pelvis or fragmentationof the stones was not completed owing to stone position or displacement and F-URS was utilized for retrograde intrarenal surgery(RIRS) (group 2). The predictive factors for F-URS requirement during RIRS for RPS were evaluated. Both groups were compared regardingage, height, sex, body mass index, stone size, stone opacity, hydronephrosis, and previous treatments. Results: The mean patient age was 48.6±16.5 years and the mean follow-period was 39±11.5 weeks. The overall stone-free rate inthe study population was 85% (75 patients). In groups 1 and 2, the overall stone-free rates were 83% (40 patients) and 87% (35 patients),respectively (p>0.05). The independent predictors of requirement for F-URS during RIRS were male gender, patient height,and higher degree of hydronephrosis. Conclusions: Rigid URS can be utilized in selected patients for the fragmentation of RPS sized 1 to 2 cm with outcomes similar tothat of F-URS. In case of failure of rigid URS, F-URS can be performed successfully in this group of patients.

      • KCI등재

        Effect of Type 2 Diabetes Mellitus on Prognosis of Nonmetastatic Renal Cell Cancer

        Evren Süer,Erdem Öztürk,Ömer Gülpınar,Aytaç Kayış,Sümer Baltacı 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.8

        Purpose: We evaluated the prognostic value of type 2 diabetes mellitus (DM) in patients treated surgically for localized renal cell carcinoma (RCC). Materials and Methods: Between 1995 and 2011, 588 patients with renal tumor diagnoses were treated surgically and 492 patients with pathologically confirmed nonmetastatic RCC diagnoses were included in the study. The associations of clinical and pathologic parameters with a type 2 DM diagnosis were evaluated. Kaplan-Meier estimations for disease-specific survival (DSS) and overall survival (OS) were generated according to type 2 DM diagnosis, and the log-rank test was used to compare survival according to the variables. Results: The mean age of the patients was 56.7±12 years (range, 15 to 84 years; median, 58 years) and the mean length of follow-up was 35.9±28 months (range, 1 to 145 months; median, 34.3 months). Of the 492 patients, 62 (12.6%) had a diagnosis of DM at the time of surgery (group I) and 430 did not have DM (group II). The mean age and the incidence of clear cell RCC histological subtype were significantly higher in group I than in group II (p<0.001 and p=0.036, respectively). Although DSS and OS were lower in group I, this difference was not significant. Type 2 DM was not detected as an independent prognostic factor for DSS and OS. Conclusions: This study investigated the role and effect of DM on the prognosis of localized RCC that was treated surgically. The present study did not detect DM as an independent prognostic factor for RCC.

      • KCI등재
      • KCI등재

        Synergistic effect of binanoenzyme and cryogel column on the production of formic acid from carbondioxide

        Yi gitcan Sümbelli,Özlem Biçen Ünlüer,Arzu Ersöz,Rıdvan Say 한국공업화학회 2019 Journal of Industrial and Engineering Chemistry Vol.76 No.-

        In this study, binanoenzyme (BNE) was synthesized using FateDH and Cyt-C in same bionano-interface;by formation of formate dehydrogenase-co-cytochrome C by using ANADOLUCA method. Thesynthesized novel binanoenzyme was embedded into HEMA based cryogel column and the conversionof CO2 to formic acid was investigated by using this cryogel column. To maintain the conversion, CO2saturated water was passed through the cryogel column and the converted formic acid was analyzedusing HPLC. The parameters which has an effect on conversion such as pH, sample volume and CO2concentration were analyzed. The results showed that the conversion process was succeeded effectively.

      • Layer-by-Layer Assembled Films of Perylene Diimide- and Squaraine-Containing Metal–Organic Framework-like Materials: Solar Energy Capture and Directional Energy Transfer

        Park, Hea Jung,So, Monica C.,Gosztola, David,Wiederrecht, Gary P.,Emery, Jonathan D.,Martinson, Alex B. F.,Er, Sü,leyman,Wilmer, Christopher E.,Vermeulen, Nicolaas A.,Aspuru-Guzik, Alá,n,S American Chemical Society 2016 ACS APPLIED MATERIALS & INTERFACES Vol.8 No.38

        <P>We demonstrate that thin films of metal organic framework (MOF)-like materials, containing two perylenedlimides (PDICl4, PDIOPh2) and a squaraine dye (S1); can be fabricated by, layer-by-layer assembly (LbL). Interestingly, these LbL films absorb across the visible light region (400-750 nm) and facilitate directional energy transfer. Due to the high spectral overlap and oriented transition dipole moments of the donor (PDICl4 and PDIOPh2) and acceptor (S1) components, directional long-range energy transfer from the bluest to reddest absorber was successfully demonstrated in the multicomponent MOF-like films. These findings have significant implications for the development of solar energy conversion devices based on MOFs.</P>

      • KCI등재

        Functional Outcomes and Long-term Durability of Artificial Urinary Sphincter Application: Review of 56 Patients With Long-term Follow-up

        Ömer Gülpınar,Evren Süer,Mehmet İlker Gökce,Ahmet Hakan Haliloğlu,Erdem Öztürk,Nihat Arıkan 대한비뇨의학회 2013 Investigative and Clinical Urology Vol.54 No.6

        Purpose: To evaluate the long-term outcomes of artificial urinary sphincter (AUS) implantation and to report the complication rates, including mechanical failure, erosion,and infection. Materials and Methods: From June 1990 to May 2011, AUS (AMS 800) implantations were performed in 56 adult males by one surgeon. Various demographic and preoperative variables, surgical variables, and postoperative outcomes, including success and complication rates with a median follow-up of 96 months, were recorded retrospectively. Results: The mean age of the patients at the time of AUS implantation was 61.8 (±14.2)years. During the follow-up period, the total complication rate was 41.1% (23 patients). The incidence of complications was significantly lower during the follow-up period after 48 months (p<0.05). Kaplan-Meier analysis revealed that 5- and 10-year failure-free rates were 50.3% and 45.2%, respectively. Conclusions: Long-term durability and functional outcomes are achievable for the AMS 800, but there are appreciable complication rates for erosion, mechanical failure, and infection of up to 30%.

      • KCI등재

        Clinical comparison of intraoral CMOS and PSP detectors in terms of time efficiency, patient comfort, and subjective image quality

        Kamburoğlu Kıvanç,Samunahmetoğlu Erçin,Eratam Nejlan,Sönmez Gül,Karahan Sevilay 대한영상치의학회 2022 Imaging Science in Dentistry Vol.52 No.1

        Purpose: This study compared the effectiveness of complementary metal-oxide semiconductors (CMOS) and photostimulable phosphor (PSP) plates as intraoral imaging systems in terms of time efficacy, patient comfort, and subjective image quality assessment in real clinical settings. Materials and Methods: Fifty-eight patients (25 women and 33 men) were included. Patients were referred for a full-mouth radiological examination including 1 bitewing radiograph (left and right) and 8 periapical radiographs for each side (left maxilla/mandible and right maxilla/mandible). For each patient, 1 side of the dental arch was radiographed using a CMOS detector, whereas the other side was radiographed using a PSP detector, ensuring an equal number of left and right arches imaged by each detector. Clinical application time, comfort/pain, and subjective image quality were assessed for each detector. Continuous variables were summarized as mean±standard deviation. Differences between detectors were evaluated using repeated-measures analysis of variance. P<0.05 was accepted as significant. Results: The mean total time required for all imaging procedures with the CMOS detector was significantly lower than the mean total time required for imaging procedures with PSP (P<0.05). The overall mean patient comfort scores for the CMOS and PSP detectors were 4.57 and 4.48, respectively, without a statistically significant difference (P>0.05). The performance of both observers in subjectively assessing structures was significantly higher when using CMOS images than when using PSP images for all regions (P<0.05). Conclusion: The CMOS detector was found to be superior to the PSP detector in terms of clinical time efficacy and subjective image quality.

      • KCI등재

        Comparison of synthesis methods for BiOI/g-C3N4 heterojunction photocatalysts and testing their visible light activity in sugar processing wastewater treatment

        Gülen Tekin,Gülin Ersöz,Süheyda Atalay 한국공업화학회 2023 Journal of Industrial and Engineering Chemistry Vol.126 No.-

        The study focused on synthesis of BiOI/g-C3N4 heterojunction photocatalysts by various methods toinvestigate their physicochemical properties as well as their performances on photocatalytic treatmentof sugar processing wastewater. The heterojunction catalysts possessed enhanced catalytic activity comparedto the pristine BiOI and g-C3N4. In-situ growth of BiOI on g-C3N4 was determined as the mostpromising method when the pH of the synthesis medium was adjusted to 10. This method provided amore homogeneous distribution and smaller size for the BiOI clusters that formed a unique flower shapewhich enhanced the catalytic activity remarkably. This depicts that synthesis conditions are especiallyimportant to obtain desired physicochemical properties for a photocatalyst since it has a key role inthe crystal structure of BiOI. The optimum nominal weight ratio was determined as 75:25 for BiOI andg-C3N4, respectively by considering the superior morphology and the highest photocatalytic activityfor 45.30% and 23.40% total saccharide (TSC) and total organic carbon (TOC) removal, respectively. Thephotocatalytic mechanism depicted that charge separation in the heterojunction structure was accomplishedvia the new S-scheme and the oxidation of saccharides and intermediates followed differentpathways by reacting with different radicals.

      • KCI등재

        Effects of Chronic and Acute Lithium Treatment on the Long-term Potentiation and Spatial Memory in Adult Rats

        Marwa Yousef,Şehrazat Kavraal,Ayşe Seda Artış,Cem Süer 대한정신약물학회 2019 CLINICAL PSYCHOPHARMACOLOGY AND NEUROSCIENCE Vol.17 No.2

        Objective: Although, accumulating evidence is delineating a neuroprotective and neurotrophic role for lithium (Li), inconsistent findings have also been reported in human studies especially. Moreover, the effects of Li infusion into the hippocampus are still unknown. The aims of this work were (a) to assess whether basal synaptic activity and long-term potentiation (LTP) in the hippocampus are different in regard to intrahippocampal Li infusion; (b) to assess spatial learning and memory in rats chronically treated with LiCO3 in the Morris water maze. Methods: Field potentials were recorded form the dentate gyrus, stimulating perforant pathways, in rats chronically (20 mg/kg for 40 days) or acutely treated with LiCO3 and their corresponding control rats. In addition, performance of rats in a Morris water maze was measured to link behaviour of rats to electrophysiological findings. Results: LiCO3 infusion into the hippocampus resulted in enhanced LTP, especially in the late phases, but attenuated LTP was observed in rats chronically treated with Li as compared to controls. Li-treated rats equally performed a spatial learning task, but did spend less time in target quadrant than saline-treated rats in Morris water maze. Conclusion: Despite most data suggest that Li always yields neuroprotective effects against neuropathological conditions; we concluded that a 40-day treatment of Li disrupts hippocampal synaptic plasticity underlying memory processes, and that these effects of prolonged treatment are not associated with its direct chemical effect, but are likely to be associated with the molecular actions of Li at genetic levels, because its short-term effect preserves synaptic plasticity.

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