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Ryohei Fukui,Ryutarou Matsuura,Katsuhiro Kida,Sachiko Goto 한국의학물리학회 2023 의학물리 Vol.34 No.3
Purpose: In radiomics analysis, to evaluate features, and predict genetic characteristics and survival time, the pixel values of lesions depicted in computed tomography (CT) and magnetic resonance imaging (MRI) images are used. CT and MRI offer three-dimensional images, thus producing three-dimensional features (Features_3d) as output. However, in reports, the superiority between Features_3d and two-dimensional features (Features_2d) is distinct. In this study, we aimed to investigate whether a difference exists in the prediction accuracy of radiomics analysis of lung cancer using Features_2d and Features_3d. Methods: A total of 38 cases of large cell carcinoma (LCC) and 40 cases of squamous cell carcinoma (SCC) were selected for this study. Two- and three-dimensional lesion segmentations were performed. A total of 774 features were obtained. Using least absolute shrinkage and selection operator regression, seven Features_2d and six Features_3d were obtained. Results: Linear discriminant analysis revealed that the sensitivities of Features_2d and Features_3d to LCC were 86.8% and 89.5%, respectively. The coefficients of determination through multiple regression analysis and the areas under the receiver operating characteristic curve (AUC) were 0.68 and 0.70 and 0.93 and 0.94, respectively. The P -value of the estimated AUC was 0.87. Conclusions: No difference was found in the prediction accuracy for LCC and SCC between Features_2d and Features_3d.
Anti-Cancer and Radiation Protection Effects by Ganoderma Lucidum
Yeunhwa Gu,Kouri Ryutarou,Takashi Nakamura,Kenichiro Tanaka,Masayuki Tajima,Takenori Yamashita,Hiroaki Tanabe,Daigo Matsumoto,Hajime Monzen,Masami Oshima,Eunsuk Choi,Ikukatsu Suzuki,Kyoo Seok Ahn,Tets 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8
Anti-Cancer and Radiation Protection Effects by Ganoderma Lucidum
Yeunhwa Gu,Kouri Ryutarou,Takashi Nakamura,Kenichiro Tanaka,Masayuki Tajima,Takenori Yamashita,Hiroaki Tanabe,Daigo Matsumoto,Hajime Monzen,Masami Oshima,Eunsuk Choi,Ikukatsu Suzuki,Kyoo Seok Ahn,Tets 한의병리학회 2004 대한동의병리학회 학술대회논문집 Vol.2004 No.8
Fukui Ryohei,Miho Numata,Saki Nishioka,Ryutarou Matsuura,Katsuhiro Kida,Sachiko Goto 한국의학물리학회 2022 의학물리 Vol.33 No.4
Purpose: To clarify the relationship between the diameter of the simulated bead and the Z-resolution of the tomosynthesis image. Methods: A simulated bead was placed on a 1,024×1,024×1,024-pixel base image. The diameters were set to 0.025, 0.05, 0.1, 0.2, 0.3, 0.7, 1.0, and 1.3 mm. A bead was placed at the center of the base image and projected at a simulated X-ray angle range of ±45° to obtain a projected image. A region of interest was placed at the center of the bead image and the slice sensitivity profile (SSP) was obtained by acquiring pixel values in the z-direction. The full width at half maximum of the SSP was defined as the Z-resolution and the frequency response was obtained by the 1-D Fourier transform of the SSP. Results: Z-resolution increased with increasing bead diameter. However, there was no change in Z-resolution between 0.025 and 0.1 mm. The frequency response was similar to that of the Z-resolution, with a significant difference between 0.1 and 0.2 mm diameter. Conclusions: Z-resolution is dependent on the diameter of the bead, which should be selected considering the pixel size of the tomosynthesis image.