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巨?良 청주대학교 국제협력연구원 2005 國際文化硏究 Vol.23 No.-
网络型企业组织是一种介于企业与市场之间的中间组织, 是继U型、M型之后又一种新型的企业组织结构模式。分工与专业化、交易费用和企业竞争战略理论, 是这种新型企业组织产生的理论基础。企业组织网络化首先引起了企业组织结构的革命性变革, 柔性化、扁平化、网络化成为有竞争力的企业组织结构的显著特点。企业组织网络化是企业面对激烈的市场竞争环境提高经济效率的自组织结果, 企业网络兴起的背后是合作性竞争的新型竞争关系的建立。 Network firm organization is medium organization between marked and enterprise, another new structure model after U-type and M-type. Division and specialization, transaction costs and the theory of enterprise competition strategy are the theoretic basis of the emerging. Network of firm organization caused its revolutionary reform. The characters of the structure are soft, flat and network. Network of firm organizations is the self-organization result of increasing economic efficiency in cruel market competition. The foundation of new cooperative relationship leads to the rising of enterprise network.
居瑢(Rong Ju),邵照阳(Zhaoyang Shao) YIXIN 출판사 2024 Journal of Humanities and Social Sciences Vol.2 No.1
在乡村振兴背景下,传统农耕文化作为劳动人民数千年的物质成果和精神财富,在实现乡村文化振兴、产业振兴和生态振兴的过程中发挥着重要作用。本文在把握传统农耕文化时代价值的基础上,从文化教育、特色产业发展等多个层面探寻了传承农耕文化的路径,从助力乡村振兴的角度提出了旅游资源、文化资源和生态资源的开发模式,通过深入挖掘和利用传统农耕文化资源推动乡村建设,为乡村繁荣发展提供内在动力。 Against the backdrop of rural revitalization, traditional agricultural culture, as the material and spiritual wealth of laboring people for thousands of years, plays a crucial role in achieving the revitalization of rural culture, industry, and ecology. Based on understanding the contemporary value of traditional agricultural culture, this paper explores the paths of inheriting agricultural culture from various perspectives such as cult ural education and the development of characteristic industries. From the perspective of supporting rural revitalization, it proposes a development model for tourism, cultural, and ecological resources. By thoroughly exploring and utilizing the resources of traditional agricultural culture, the paper aims to drive rural development, providing intrinsic momentum for the prosperity and development of rural areas.
Chromatographic Behavior of Proteins on Stationary Phase with Aminocarboxy Ligand
Rong Li,Ming-Yang Ju,Bin Chen,Qing-Yuan Sun,Guo-Liang Chen,Mei Shi,Xiao-Gang Wang,Jian-Bin Zheng 대한화학회 2011 Bulletin of the Korean Chemical Society Vol.32 No.2
An aminocarboxy aspartic acid-bonded silica (Asp-Silica) stationary phase was synthesized using L-aspartic acid as ligand and silica gel as matrix. The standard protein mixtures were separated with prepared chromatographic column. The effects of solution pH, salt concentration and metal ion on the retention of proteins were examined, and also compared with traditional iminodiacetic acid-bonded silica (IDA-Silica) column. The results show that Asp-Silica column exhibited an excellent separation performance for proteins. The retention of proteins on Asp-Silica stationary phase was consistent with electrostatic characteristic of cation-exchange. The stationary phase displayed typical metal chelate property after fixing copper ion (II) on Asp-Silica. Under competitive eluting condition, protein mixtures were effectively isolated. Asp ligand showed better ion-exchange and metal chelating properties as compared with IDA ligand.
Rong Zhang,Lei Li,Huihui Li,Hansong Bai,Yuping Suo,Ju Cui,Yingmei Wang 고려인삼학회 2024 Journal of Ginseng Research Vol.48 No.1
Background: Ginsenoside 20(S)-Rg3 shows promising tumor-suppressive effects in ovarian cancer viainhibiting NF-kB signaling. This study aimed to explore the downstream tumor suppressive mechanismsof ginsenoside Rg3 via this signaling pathway. Materials and methods: A systematical screening was applied to examine the expression profile of 41kinesin family member genes in ovarian cancer. The regulatory effect of ginsenoside Rg3 on KIF20Aexpression was studied. In addition, we explored interacting proteins of KIF20A and their molecularregulations in ovarian cancer. RNA-seq data from The Cancer Genome Atlas (TCGA) was used for bioinformaticanalysis. Epithelial ovarian cancer cell lines SKOV3 and A2780 were used as in vitro and in vivocell models. Commercial human ovarian cancer tissue arrays were used for immunohistochemistrystaining. Results: KIF20A is a biomarker of poor prognosis among the kinesin genes. It promotes ovarian cancercell growth in vitro and in vivo. Ginsenoside Rg3 can suppress the transcription of KIF20A. GST pull-downand co-immunoprecipitation (IP) assays confirmed that KIF20A physically interacts with BTRC (b-TrCP1),a substrate recognition subunit for SCFb TrCP E3 ubiquitin ligase. In vitro ubiquitination and cycloheximide(CHX) chase assays showed that via interacting with BTRC, KIF20A reduces BTRC-mediated CDC25Apoly-ubiquitination and enhances its stability. Ginsenoside Rg3 treatment partly abrogates KIF20Aoverexpression-induced CDC25A upregulation. Conclusion: This study revealed a novel anti-tumor mechanism of ginsenoside Rg3. It can inhibit KIF20Atranscription and promote CDC25A proteasomal degradation in epithelial ovarian cancer.
Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway
Lee, Ju-Hee,Jung, Ji Yun,Jang, Eun Jeong,Jegal, Kyung Hwan,Moon, Soo Young,Ku, Sae Kwang,Kang, Seung Ho,Cho, Il Je,Park, Sook Jahr,Lee, Jong Rok,Zhao, Rong Jie,Kim, Sang Chan,Kim, Young Woo SAGE Publications 2015 Experimental biology and medicine Vol.240 No.4
Yoon, Ju-An,Kim, You-Hyun,Kim, Nam Ho,Yoo, Seung Il,Lee, Sang Youn,Zhu, Fu Rong,Kim, Woo Young Springer 2014 NANOSCALE RESEARCH LETTERS Vol.9 No.1
<P>In this study, the properties of blue organic light-emitting diodes (OLEDs), employing quantum well-like structure (QWS) that includes four different blue emissive materials of 4,4′-bis(2,2′-diphenylyinyl)-1,1′-biphenyl (DPVBi), 9,10-di(naphth-2-yl)anthracene (ADN), 2-(<I>N</I>,<I>N</I>-diphenyl-amino)-6-[4-(<I>N</I>,<I>N</I>-diphenyl amine)styryl]naphthalene (DPASN), and bis(2-methyl-8-quinolinolate)-4-(phenyl phenolato) aluminum (BAlq), were investigated. Conventional QWS blue OLEDs composed of multiple emissive layers and charge blocking layer with lower highest occupied molecular orbital (HOMO)-lowest unoccupied molecular orbital (LUMO) energy level, and devices with triple emissive layers for more significant hole-electron recombination and a wider region for exciton generation were designed. The properties of triple emissive layered blue OLEDs with the structure of indium tin oxide (ITO) /<I>N</I>,<I>N</I>′-diphenyl-<I>N</I>,<I>N</I>′-bis(1-naphthyl-phenyl)-(1,1′-biphenyl)-4,4′-diamine (NPB) (700 Ǻ)/X (100 Ǻ)/BAlq (100 Ǻ)/X (100 Ǻ)/4,7-diphenyl-1,10-phenanthroline (Bphen) (300 Ǻ)/lithium quinolate (Liq) (20 Ǻ)/aluminum (Al) (1,200 Ǻ) (X = DPVBi, ADN, DPASN) were examined. HOMO-LUMO energy levels of DPVBi, ADN, DPASN, and BAlq are 2.8 to 5.9, 2.6 to 5.6, 2.3 to 5.2, and 2.9 to 5.9 eV, respectively. The OLEDs with DPASN/BAlq/DPASN QWS with maximum luminous efficiency of 5.32 cd/A was achieved at 3.5 V.</P>