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Rezaul H. Ansary,Mokhlesur M. Rahman,Mohamed B. Awang,Haliza Katas,Hazrina Hadi,Farahidah Mohamed,Abd Almonem Doolaanea,Yunus B. Kamaruzzaman 대한약학회 2016 Archives of Pharmacal Research Vol.39 No.9
The aim of this study was to prepare a model protein, bovine serum albumin (BSA) loaded double-walled microspheres using a fast degrading glucose core, hydroxyl-terminated poly(lactide-co-glycolide) (Glu- PLGA) and a moderate-degrading carboxyl-terminated PLGA polymers to reduce the initial burst release and to eliminate the lag phase from the release profile of PLGA microspheres. The double-walled microspheres were prepared using a modified water-in-oil-in-oil-in-water (w/o/o/ w) method and single-polymer microspheres were prepared using a conventional water-in-oil-in-water (w/o/w) emulsion solvent evaporation method. The particle size, morphology, encapsulation efficiency, thermal properties, in vitro drug release and structural integrity of BSA were evaluated in this study. Double-walled microspheres prepared with Glu-PLGA and PLGA polymers with a mass ratio of 1:1 were non-porous, smooth-surfaced, and spherical in shape. A significant reduction of initial burst release was achieved for the double-walled microspheres compared to single-polymer microspheres. In addition, microspheres prepared using Glu-PLGA and PLGA polymers in a mass ratio of 1:1 exhibited continuous BSA release after the small initial burst without any lag phase. It can be concluded that the double-walled microspheres made of Glu-PLGA and PLGA polymers in a mass ratio of 1:1 can be a potential delivery system for pharmaceutical proteins.
Md Rezaul Karim,Thi Hiep Han,Sandesh Y. Sawant,심재진,이문용,김우경,김종수,조무환 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.7
This paper reports the simultaneous synthesis of gold nanoparticles (AuNPs) with a spherical and stable structure using microbial fuel cell (MFC) biofilms. The green, facile, chemical stabilizers and capping-agent free AuNPs synthesis allow the binder-free in situ decoration of AuNPs on MFC anode electrode with the help of special interactions of biofilm. The MFC with AuNPs decorated carbon foam anode electrode produced 62.5% higher (46.37Wm3) power density than that of the MFC equipped with plain carbon foam anode (control). The AuNPs facilitated the good adhesion of bacteria, amplified the conductivity, and reduced the internal resistance, resulting in improved overall MFC performance. In addition, the peroxide-mimicking activity was evaluated and the MFC-synthesized AuNPs exhibited significantly higher peroxidase mimicking activity than the chemically synthesized AuNPs, thereby, allowing the easy and rapid colorimetric detection of hydrogen peroxide with a detection limit of 20 M.
Md. Rezaul Karim,최호진,Md. Mamunur Rashid,정병수 한국유전체학회 2012 Genomics & informatics Vol.10 No.1
Mining interesting patterns from DNA sequences is one of the most challenging tasks in bioinformatics and computational biology. Maximal contiguous frequent patterns are preferable for expressing the function and structure of DNA sequences and hence can capture the common data characteristics among related sequences. Biologists are interested in finding frequent orderly arrangements of motifs that are responsible for similar expression of a group of genes. In order to reduce mining time and complexity, however, most existing sequence mining algorithms either focus on finding short DNA sequences or require explicit specification of sequence lengths in advance. The challenge is to find longer sequences without specifying sequence lengths in advance. In this paper, we propose an efficient approach to mining maximal contiguous frequent patterns from large DNA sequence datasets. The experimental results show that our proposed approach is memory-efficient and mines maximal contiguous frequent patterns within a reasonable time.
( Mohammad Rezaul Karim ) 한국행정학회 2013 한국행정학회 학술발표논문집 Vol.2013 No.-
This article aims at examining the impact of globalization on working women in private sector organizations (PSOs) in Bangladesh. Private sector emerges in 1980s with a wide opportunity of employment. The huge demand of frozen foods, garments and knitting accessories across the world opened the opportunity for Bangladesh to enter the global market. The high rate of unemployment creates availability of cheap labor and attracts foreign buyers. PSOs employ mostly rural poor women for various reasons. The total employee was about 0.2 million in 1985 that increased to 4 million in 2010 including more than 80 percent women workers. There has been a significant increase in the women labor force who transformed from informal sector to formal sector. The globalization brought opportunity for them with several benefits such as, creation of new jobs, utilization of human capital, workplace facilities (minimum wage system, maternity leave, childcare facility, trade union), economic empowerment of women, mobility in public domain, increasing social status and prestige, self-esteem, increasing calorie intake, developing health awareness and reduces absolute poverty. Besides, it brings negative aspects as well. Due to the globalization there are many negative issues arose such as health hazards because of unhealthy and unhygienic working environment, physical vulnerability, increasing degree of familial responsibility, fear of losing jobs at any time, treating bad girl in the society, getting late or not married leading to scarcity of human resources in future. In order to maintain the sustainable economic and social development of Bangladesh, government should play the important role as a controlled mechanism.
M. Rezaul Islam 한국사회복지학회 2014 Asian Social Work and Policy Review Vol.8 No.3
This paper exposed the major challenges that the non-governmental organizations (NGOs) face in improving development ownership among vulnerable people in community empowerment projects in Bangladesh. The finding, based on a qualitative research approach, used multi-method data collection procedures. Data were collected from two NGOs, Proshika and Practical Action Bangladesh (PAB), working with two vulnerable communities—blacksmiths and goldsmiths. The results showed that NGOs faced a number of challenges, including lack of understanding about the local context, initiatives to localize global development tools, developing partnership, and space for local people in the development processes. The paper argued that, without securing development ownership, the NGOs’ activities toward community empowerment of vulnerable people would not be possible. The findings of the paper would be valuable guidelines for policy makers, development practitioners, NGO workers, and academicians.
Optimization of Spray Drying Parameters for Pink Guava Powder Using RSM
Mohammad Rezaul Islam Shishir,farah saleenataip,Norashikin Ab. Aziz,rosnita a . talib,Md. Sazzat Hossain Sarker 한국식품과학회 2016 Food Science and Biotechnology Vol.25 No.2
The optimization of pink guava was executed using central composite face-centred design to optimize the spray drying parameters of inlet temperature, maltodextrin concentration (MDC) and feed flow (FF). The experimental results were significantly (p<0.01) fitted into second-order polynomial models to describe and predict the response quality in terms of the final moisture, particle size and lycopene with R2 of 0.9749, 0.9616, and 0.9505, respectively. The final moisture content significantly (p<0.01) decreased with increasing inlet temperature and MDC, whereas the particle size increased. In contrast, the lycopene content significantly (p<0.01) decreased with the higher temperature and increased with increasing MDC. However, according to multiple response optimization, the optimum conditions of 150oC inlet temperature, 17.12% (w/v) MDC and 350 mL/h FF-predicted 3.10% moisture content, 11.23 μm particle size and 58.71 mg/100 g lycopene content. The experimental observation satisfied the predicted model within the acceptable range of the responses.
Hunger Reduction in China: An Analysis of Contextual Factors
M. Rezaul Islam 한국사회복지학회 2016 Asian Social Work and Policy Review Vol.10 No.3
In recent times, China has significantly reduced hunger in its populace. The main objective of this paper was to analyze some of the contextual socioeconomic factors contributing to the reduction of hunger in China, using Qualitative Interpretative Meta-Synthesis (QIMS). The results revealed that China has followed a broad-based and multispectral approach to reduce hunger. Factors, such as poverty alleviation; social safety nets for disadvantaged villagers; agricultural development and land reforms; regional development and equity in development activities; infrastructural development; and political-economic reform and sustainable growth were influential in reducing hunger in China. Poverty is attributed as one of the principal contributors and is interlinked with many other dimensions. The findings of this paper are a useful guide to the Chinese government, policy-makers, international organizations, and development practitioners.