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        Accuracy of Freehand versus Navigated Thoracolumbar Pedicle Screw Placement in Patients with Metastatic Tumors of the Spine

        De La Garza Ramos, Rafael,Echt, Murray,Benton, Joshua A.,Gelfand, Yaroslav,Longo, Michael,Yanamadala, Vijay,Yassari, Reza The Korean Neurosurgical Society 2020 Journal of Korean neurosurgical society Vol.63 No.6

        Objective : To compare the accuracy and breach rates of freehand (FH) versus navigated (NV) pedicle screws in the thoracic and lumbar spine in patients with metastatic spinal tumors. Methods : A retrospective review of adult patients who underwent pedicle screw fixation in the thoracic or lumbar spine for metastatic spinal tumors between 2012 and 2018 was conducted. Breaches were assessed based on the Gertzbein and Robbins classification and only screws placed >4 mm outside of the pedicle wall (lateral or medial) were considered breached. Results : A total of 62 patients received 547 pedicle screws (average 8 per patient) - 34 patients received 298 pedicle screws in the FH group and 28 patients received 249 screws in the NV group. There were 40/547 breaches, corresponding to a breach and accuracy rate of 7.3% and 92.7%, respectively. The breach rate was 9.7% in the FH group and 4.4% in the NV group (chi-squared test, p=0.017); this corresponded to an accuracy rate of 90.3% and 95.6%, respectively. Only one patient from the overall cohort (in the FH group) required revision surgery due to a medial breach abutting the spinal cord (1.6% of all patients; 2.9% of FH patients); no patient suffered organ, vessel, or neurological injury from screw breaches. Conclusion : Navigated pedicle screw placement in patients with metastatic spinal tumors has a significantly higher radiographic accuracy compared to the FH technique. However, the revision surgery was low and no patient suffered from clinically-relevant breach. Navigation also offers the advantage of real-time localization of spinal tumors and aids in targeting and resection of these lesions.

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        Support vector machines are superior to principal components analysis for selecting the optimal bones’ CT attenuations for opportunistic screening for osteoporosis using CT scans of the foot or ankle

        Ronnie Sebro,Cynthia De la Garza-Ramos 대한골다공증학회 2022 Osteoporosis and Sarcopenia Vol.8 No.3

        Objectives: To use the computed tomography (CT) attenuation of the foot and ankle bones for opportunistic screening for osteoporosis. Methods: Retrospective study of 163 consecutive patients from a tertiary care academic center who underwent CT scans of the foot or ankle and dual-energy X-ray absorptiometry (DXA) within 1 year of each other. Volumetric segmentation of each bone of the foot and ankle was done to obtain the mean CT attenuation. Pearson's correlations were used to correlate the CT attenuations with each other and with DXA measurements. Support vector machines (SVM) with various kernels and principal components analysis (PCA) were used to predict osteoporosis and osteopenia/osteoporosis in training/validation and test datasets. Results: CT attenuation measurements at the talus, calcaneus, navicular, cuboid, and cuneiforms were correlated with each other and positively correlated with BMD T-scores at the L1-4 lumbar spine, hip, and femoral neck; however, there was no significant correlation with the L1-4 trabecular bone scores. A CT attenuation threshold of 143.2 Hounsfield units (HU) of the calcaneus was best for detection of osteoporosis in the training/validation dataset. SVMs with radial basis function (RBF) kernels were significantly better than the PCA model and the calcaneus for predicting osteoporosis in the test dataset. Conclusions: Opportunistic screening for osteoporosis is possible using the CT attenuation of the foot and ankle bones. SVMs with RBF using all bones is more accurate than the CT attenuation of the calcaneus.

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        Bi2InTaO7 compounds as promising photocatalysts for marine plankton removal

        Leticia M. Torres-Martínez,Isaías Juárez-Ramírez,Juan S. Ramos-Garza,Francisco Vázquez-Acosta,Ricardo Gómez,ZhengYi Fu,Soo Wohn Lee 한양대학교 세라믹연구소 2011 Journal of Ceramic Processing Research Vol.12 No.1

        The removal of marine plankton, red (Amphidium carterae), and green (Tetraselmis suecica) tide algae, by heterogeneous photocatalysis was carried out using pyrochlore-type semiconductors. The semiconductor, Bi2InTaO7 , was prepared by the solgel method and a solid state reaction. The XRD patterns evidence formation of the pyrochlore phase in the sol-gel materials calcined at low temperatures (600-800 oC). Nanostructured sol-gel materials were observed by SEM. The sol-gel preparation allowed the formation of the pyrochlore-type compound with specific surface areas (7-13 m2g−1) higher than the solid obtained by solid state preparation (< 5 m2g−1). Band gap (Eg) values between 2.1-2.7 eV determined by UV-Vis spectroscopy were obtained. Bi2InTaO7 photocatalysts prepared by the sol-gel method were able to eliminate Tetraselmis suecica and Amphidium carterae algae totally after 50 minutes of UV-irradiation, whereas Bi2InTaO7 by solid state preparation needed more than 1 h.

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