Enabling Vessel Collision-Avoidance Expert Systems to Negotiate

Qinyou Hu,Chaojian Shi,Haishan Chen,Qiaoer Hu 한국항해항만학회 2006 한국항해항만학회 학술대회논문집 Vol.1 No.-

Automatic vessel collision-avoidance systems have been studied in the fields of artificial intelligence and navigation for decades. And to facilitate automatic collision-avoidance decision-making in two-vessel-encounter situation, several expert and fuzzy expert systems have been developed. However, none of them can negotiate with each other as seafarers usually do when they intend to make a more economic overall plan of collision avoidance in the COLREGS-COST-HIGH situations where collision avoidance following the International Regulations for Preventing Collisions at Sea(COLREGS) costs too much. Automatic Identification System(AIS) makes data communication between two vessels possible, and negotiation methods can be used to optimize vessel collision avoidance. In this paper, a negotiation framework is put forward to enable vessels to negotiate to optimize collision avoidance in the COLREGS-COST-HIGH situations at open sea. A vessel vector space is defined and therewith a cost model is put forward to evaluate the cost of collision-avoidance actions. Negotiations between a give-way vessel and a stand-on vessel and between two give-way vessels are considered respectively to reach overall low cost agreements. With the framework proposed in this paper, two vessels involved in a COLREGS-COST-HIGH situation can negotiate with each other to get a more economic overall plan of collision avoidance than that suggested by the traditional collision-avoidance expert systems.

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype

Ren, Kaixi,Jin, Chao,Ma, Pengfei,Ren, Qinyou,Jia, Zhansheng,Zhu, Daocheng The Korean Society of Ginseng 2016 Journal of Ginseng Research Vol.40 No.2

Background: Ginsenoside Rd (GSRd), a main component of the root of Panax ginseng, exhibits anti-inflammation functions and decreases infarct size in many injuries and ischemia diseases such as focal cerebral ischemia. M1 Macrophages are regarded as one of the key inflammatory cells having functions for disease progression. Methods: To investigate the effect of GSRd on renal ischemia/reperfusion injury (IRI) and macrophage functional status, and their regulatory role on mouse polarized macrophages in vitro, GSRd (10-100 mg/kg) and vehicle were applied to mice 30 min before renal IRI modeling. Renal functions were reflected by blood serum creatinine and blood urea nitrogen level and histopathological examination. M1 polarized macrophages infiltration was identified by flow cytometry analysis and immunofluorescence staining with $CD11b^+$, $iNOS^+$/interleukin-12/tumor necrosis factor-${\alpha}$ labeling. For the in vitro study, GSRd ($10-100{\mu}g/mL$) and vehicle were added in the culture medium of M1 macrophages to assess their regulatory function on polarization phenotype. Results: In vivo data showed a protective role of GSRd at 50 mg/kg on Day 3. Serum level of serum creatinine and blood urea nitrogen significantly dropped compared with other groups. Reduced renal tissue damage and M1 macrophage infiltration showed on hematoxylin-eosin staining and flow cytometry and immunofluorescence staining confirmed this improvement. With GSRd administration, in vitro cultured M1 macrophages secreted less inflammatory cytokines such as interleukin-12 and tumor necrosis factor-${\alpha}$. Furthermore, macrophage polarization-related pancake-like morphology gradually changed along with increasing concentration of GSRd in the medium. Conclusion: These findings demonstrate that GSRd possess a protective function against renal ischemia/reperfusion injury via downregulating M1 macrophage polarization.

Ginsenoside Rd alleviates mouse acute renal ischemia/reperfusion injury by modulating macrophage phenotype

Kaixi Ren,Chao Jin,Pengfei Ma,Qinyou Ren,Zhansheng Jia,Daocheng Zhu 고려인삼학회 2016 Journal of Ginseng Research Vol.40 No.2

Background: Ginsenoside Rd (GSRd), a main component of the root of Panax ginseng, exhibits antiinflammation functions and decreases infarct size in many injuries and ischemia diseases such as focal cerebral ischemia. M1 Macrophages are regarded as one of the key inflammatory cells having functions for disease progression. Methods: To investigate the effect of GSRd on renal ischemia/reperfusion injury (IRI) and macrophage functional status, and their regulatory role on mouse polarized macrophages in vitro, GSRd (10e100 mg/ kg) and vehicle were applied to mice 30 min before renal IRI modeling. Renal functions were reflected by blood serum creatinine and blood urea nitrogen level and histopathological examination. M1 polarized macrophages infiltration was identified by flow cytometry analysis and immunofluorescence staining with CD11bþ, iNOSþ/interleukin-12/tumor necrosis factor-a labeling. For the in vitro study, GSRd (10 e100 mg/mL) and vehicle were added in the culture medium of M1 macrophages to assess their regulatory function on polarization phenotype. Results: In vivo data showed a protective role of GSRd at 50 mg/kg on Day 3. Serum level of serum creatinine and blood urea nitrogen significantly dropped compared with other groups. Reduced renal tissue damage and M1 macrophage infiltration showed on hematoxylineeosin staining and flow cytometry and immunofluorescence staining confirmed this improvement. With GSRd administration, in vitro cultured M1 macrophages secreted less inflammatory cytokines such as interleukin-12 and tumor necrosis factor-a. Furthermore, macrophage polarization-related pancake-like morphology gradually changed along with increasing concentration of GSRd in the medium. Conclusion: These findings demonstrate that GSRd possess a protective function against renal ischemia/ reperfusion injury via downregulating M1 macrophage polarization.

Isolation and Identification of Prepubertal Buffalo (Bubalus bubalis) Spermatogonial Stem Cells

Feng, Wanyou,Chen, Shibei,Do, Dagiang,Liu, Qinyou,Deng, Yanfei,Lei, Xiaocan,Luo, Chan,Huang, Ben,Shi, Deshun Asian Australasian Association of Animal Productio 2016 Animal Bioscience Vol.29 No.10

Isolation and culture of spermatogonial stem cells (SSCs) are attractive for production of genetic modified offspring. In the present study, buffalo spermatogonial stem-like cells were isolated, cultured and expression pattern of different germ cell marker genes were determined. To recover spermatogonia, testes from age 3 to 7 months of buffalo were decapsulated, and seminiferous tubules were enzymatically dissociated. Two types of cells, immature sertoli cell and type A spermatogonia were observed in buffalo testes in this stage. Germ cell marker genes, OCT3/4 (Pou5f1), THY-1, c-kit, PGP9.5 (UCHL-1) and Dolichos biflorus agglutinin, were determined to be expressed both in mRNA and protein level by reverse transcription polymerase chain reaction and immunostaining in buffalo testes and buffalo spermatogonial stem-like cells, respectively. In the following, when the isolated buffalo buffalo spermatogonial stem-like cells were cultured in the medium supplemented 2.5% fetal bovine serum and 40 ng/mL glial cell-derived neurotrophic factor medium, SSCs proliferation efficiency and colony number were significantly improved than those of other groups (p<0.05). These findings may help in isolation and establishing long term in vitro culture system for buffalo spermatogonial stem-like cells, and accelerating the generation of genetic modified buffaloes.

Structural and chemical synergistic effect of CoS nanoparticles and porous carbon nanorods for high-performance sodium storage

Zhou, Limin,Zhang, Kai,Sheng, Jinzhi,An, Qinyou,Tao, Zhanliang,Kang, Yong-Mook,Chen, Jun,Mai, Liqiang Elsevier 2017 Nano energy Vol.35 No.-

<P><B>Abstract</B></P> <P>Considering inherent large structural deterioration of conversion-type anode materials during repeated sodiation/desodiation process, the ingenious integration of both nanostructure engineering and chemical hybridization is highly desirable and challenging. Here, ultrafine CoS nanoparticles embedded in porous carbon nanorods (denoted as 7-CoS/C) were facilely fabricated via simultaneous in-situ carbonization and sulfidation of Co-metal organic frameworks (Co-MOF) and have been applied as anode materials for sodium-ion batteries (SIBs). Benefiting from the advantageous embedding architecture between the nanoparticles and porous nanorods, the 7-CoS/C delivers long-term cycling stability (542mAhg<SUP>−1</SUP> after 2000 cycles with a capacity retention of 91.4% at 1Ag<SUP>−1</SUP>) and excellent rate performance (discharge capacities of 510mAhg<SUP>−1</SUP> at 5Ag<SUP>−1</SUP> and 356mAhg<SUP>−1</SUP> even at 40Ag<SUP>−1</SUP>), which is proved to be characterized of partial pseudocapacitive behaviors during the sodiation/desodiation process. In addition, Na<SUB>3</SUB>V<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB>/7-CoS/C full cell with excessive amount of Na<SUB>3</SUB>V<SUB>2</SUB>(PO<SUB>4</SUB>)<SUB>3</SUB> has been assembled and exhibits a capacity of 352mAhg<SUP>−1</SUP> at 0.5Ag<SUP>−1</SUP>. This meaningful approach can be extended to build embedded porous structure of other hybrid composites for next-generation energy-storage technology.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The embedded hybrid architecture of the 7-CoS/C is favorable for relieving volume expansion and immobilizing the CoS nanoparticles sites. </LI> <LI> The effect of different electrolyte on the 7-CoS/C/Na system was investigated. </LI> <LI> The variation of structure and valence in Na<SUP>+</SUP> insertion/extraction process of the 7-CoS/C is presented by <I>ex situ</I> XANES. </LI> <LI> The unique structural feature of the 7-CoS/C reveals obvious advantages at more than 1Ag<SUP>−1</SUP> compared with other anode materials. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>

Salt-controlled dissolution in pigment cathode for high-capacity and long-life magnesium organic batteries

Cui, Lianmeng,Zhou, Limin,Zhang, Kai,Xiong, Fangyu,Tan, Shuangshuang,Li, Maosheng,An, Qinyou,Kang, Yong-Mook,Mai, Liqiang Elsevier 2019 Nano energy Vol.65 No.-

<P><B>Abstract</B></P> <P>Benefiting from high volumetric energy density and generally dendrite-free growth of Mg metal, rechargeable magnesium batteries (MBs) become a promising next-generation energy storage system. Organic electrode materials, with characteristic of sustainable resource and flexible structure, have been widely studied in alkali metal ion batteries, but are rarely reported in MBs. Herein, we demonstrate that 3,4,9,10-perylenetetracarboxylic dianhydride (PTCDA) serves as a cathode material for MBs in non-aqueous system, which realizes a fast diffusion kinetics and remarkable Mg-storage performance through a salt-dissolution inhibition approach for the electrolyte. The PTCDA exhibits a reversible capacity of 126 mAh g<SUP>−1</SUP> (at 200 mA g<SUP>−1</SUP>), excellent rate performance, and good cycling stability (100 mAh g<SUP>−1</SUP> even after 150 cycles). Furthermore, the evolution mechanism of the PTCDA electrode based on the transformation between carbonyl groups (CO) and enolate groups (C–O) is revealed by <I>ex-situ</I> phase characterization and functional group analysis. Besides, the dissolution inhibition of the PTCDA could also be realized through the incorporation of other soluble salt (KCl or NaCl) into all phenyl complex (APC) electrolyte, resulting in an enhanced cycling capacity. Considering the designable configuration of the organic materials, this work would pave way for their utilization on multi-valent ion batteries and provide efficient strategy to realize high voltage and satisfied cycle life.</P> <P><B>Highlights</B></P> <P> <UL> <LI> The magnesium anode in organic system was realized combined with the solubility inhibition of the host materials. </LI> <LI> Compared with other inorganic cathode materials, the PTCDA is eligible to offset the defect of Mg<SUP>2+</SUP> transport dynamics. </LI> <LI> Compared with other Mg-storage materials reported, the PTCDA demonstrates a high working voltage plateau and a small polarization. </LI> <LI> The electrochemical mechanism of the PTCDA is proved to be the transformation between carbonyl groups and enolate groups. </LI> <LI> The incorporation of dissolvable salts inhibited the dissolution of the PTCDA. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>