Thin Film Fabrications : PREPARATION AND CHARACTERIZATION OF THIN FILMS OF Pb ( Fe½Nb½ ) O3 MADE BY A SOL - GEL METHOD

Qingxin Su,Ji Zhou,K . M . Moulding,D . J . Barber 대한금속재료학회 ( 구 대한금속학회 ) 1995 Advanced Material and Processing Vol.1 No.-

Temozolomide Drives Ferroptosis via a DMT1-Dependent Pathway in Glioblastoma Cells

Qingxin Song,Shanxin Peng,Zhiqing Sun,Xueyuan Heng,Xiaosong Zhu 연세대학교의과대학 2021 Yonsei medical journal Vol.62 No.9

Purpose: Temozolomide is used in first-line treatment for glioblastoma. However, chemoresistance to temozolomide is commonin glioma patients. In addition, mechanisms for the anti-tumor effects of temozolomide are largely unknown. Ferroptosis is a formof programmed cell death triggered by disturbed redox homeostasis, overloaded iron, and increased lipid peroxidation. The presentstudy was performed to elucidate the involvement of ferroptosis in the anti-tumor mechanisms of temozolomide. Materials and Methods: We utilized the CCK8 assay to evaluate cytotoxicity. Levels of lactate dehydrogenase (LDH), malondialdehyde(MDA), iron, and glutathione (GSH) were measured. Flow cytometry and fluorescence microscope were used to detectthe production of reactive oxygen species (ROS). Western blotting, RT-PCR and siRNA transfection were used to investigate molecularmechanisms. Results: Temozolomide increased the levels of LDH, MDA, and iron and reduced GSH levels in TG905 cells. Furthermore, wefound that ROS levels and DMT1 expression were elevated in TG905 cells treated with temozolomide and were accompanied bya decrease in the expression of glutathione peroxidase 4, indicating an iron-dependent cell death, ferroptosis. Our results alsoshowed that temozolomide-induced ferroptosis is associated with regulation of the Nrf2/HO-1 pathway. Conversely, DMT1 knockdownby siRNA evidently blocked temozolomide-induced ferroptosis in TG905 cells. Conclusion: Taken together, our findings indicate that temozolomide may suppress cell growth partly by inducing ferroptosis bytargeting DMT1 expression in glioblastoma cells.

Electricity Load Forecast Emulation Research Based on the Multi-model Merit

Qingxin Zhang,Zhanbo Cui,Luping Wang,Yanki Zhou 보안공학연구지원센터 2014 International Journal of Control and Automation Vol.7 No.4

Research and Experimental Analysis of Damping Characteristics of Magnetic Shape Memory Alloy

Zhang Qingxin,Fu Qihang,Wang Luping,Gao Yunhong 한국전기전자재료학회 2018 Transactions on Electrical and Electronic Material Vol.19 No.4

This paper systematically illustrates the deformation and damping mechanism of magnetic shape memory alloy (MSMA)and builds a damping mathematical model by using a single-degree-of-freedom vibration system. The results indicate thatabsorbed damping is proportional to the quadratic of external force and inversely proportional to the overall mass, the naturalfrequency and the total damping of the system when the system is in resonance. At the same time, the paper calculates therelative power and draws the stress–strain curve of mechanical property. The relations among temperature, stress, intensityof magnetic induction, and deformation of MSMA are studied through a static experiment. Meanwhile, an analysis of thedamping characteristic indicates that the external force is 25–30 N when the temperature ranges from 23 to 29 °C and thatthe deformation rate is the largest and the damping performance is the best at a magnetic induction strength of 0.55 T.

近代科學思潮與黃人《中國文學史》之編撰

?慶新(Wen Qingxin) 중국어문학연구회 2011 중국어문학논집 Vol.0 No.67

There is a close relation between the modern scientific trends and HuangRen’s “Chinese literature history”,especially on the three aspects,such as The theory of evolution,The modern geometry and Newton mechanics. All of these had a big impact on HuangRen’s works. A new view and methodologic consideration was given to HuangRen after had touched the modern scientific trends.

The effect of 8 weeks of weight-bearing exercise on cognitive function, fitness, and health-related quality of life in older adults: a randomized controlled trial

( Hyoungsue Kim ),( Qingxin Ji ),( Taehun Kim ),( Junga Lee ) 대한운동사협회 2022 대한운동사협회 운동사대회자료집 Vol.2022 No.-

Background: The purpose of this study was to investigate the effect of 8 weeks of weight-bearing exercise on cognitive function, fitness, and health-related quality of life in older adults. Methods: A total of 30 adults with 65 years of age or older were randomly divided into two groups: an exercise group and a control group. The exercise group participated in an online video whole body exercise intervention and the control group was instructed to maintain daily activities unchanged. The mini mental status examination (MMSE), Seiner fitness test (SFT), and health-related quality of life (QL) questionnaire were performed before and after this intervention periods. An independent t-test was used for comparisons between the two groups, and a two-way repeated ANOVA was used to calculate the interaction between the two groups and across time. We used a paired-test to compare pre- and post-test data. Results: Participating in weight-bearing exercise increased attention, recall, and repetition of cognitive functions. Older adults in the exercise group increased their two-minute walk and chair sit and reach in the senior fitness test. Health-related quality of life increased, but there was no statistically significant change. Conclusion: Eight weeks of weight-bearing exercise may improve cognitive function, physical fitness, and health-related quality of life in older adults. Further studies examining the effects of exercise on more participants with cognitive decline should help us derive specific recommendations to maintain health in older adults.

Investigation on vibration behavior of a high-speed railway bridge based on monitoring data

Hao Wang,Qingxin Zhu,Billie F. Spencer Jr 국제구조공학회 2023 Smart Structures and Systems, An International Jou Vol.31 No.6

Field monitoring techniques offer an attractive approach for understanding bridge behavior under in-service loads. However, the investigations on bridge behavior under high-speed train load using field monitoring data are limited. The focus of this study is to explore the structural behavior of an in-service long-span steel truss arch bridge based on field monitoring data. First, the natural frequencies of the structure, as well as the train driving frequencies, are extracted. Then, the train-induced bearing displacement and structural strain are explored to identify the effects of train loads and bearings. Subsequently, a sensitivity analysis is performed for the impact factor of strain responses with respect to the train speed, train weight, and temperature to identify the fundamental issues affecting these responses. Additionally, a similar sensitivity analysis is conducted for the peak acceleration. The results indicate that the friction force in bearings provides residual deformations when two consecutive trains are in opposite directions. In addition, the impact factor and peak acceleration are primarily affected by train speed, particularly near train speeds that result in the resonance of the bridge response. The results can provide additional insight into the behavior of the long-span steel truss bridges under in-service high-speed train loads.

Identification of moving train loads on railway bridge based on strain monitoring

Hao Wang,Qingxin Zhu,Jian Li,Jianxiao Mao,Suoting Hu,Xinxin Zhao 국제구조공학회 2019 Smart Structures and Systems, An International Jou Vol.23 No.3

Moving train load parameters, including train speed, axle spacing, gross train weight and axle weights, are identified based on strain-monitoring data. In this paper, according to influence line theory, the classic moving force identification method is enhanced to handle time-varying velocity of the train. First, the moments that the axles move through a set of fixed points are identified from a series of pulses extracted from the second derivative of the structural strain response. Subsequently, the train speed and axle spacing are identified. In addition, based on the fact that the integral area of the structural strain response is a constant under a unit force at a unit speed, the gross train weight can be obtained from the integral area of the measured strain response. Meanwhile, the corrected second derivative peak values, in which the effect of time-varying velocity is eliminated, are selected to distribute the gross train weight. Hence the axle weights could be identified. Afterwards, numerical simulations are employed to verify the proposed method and investigate the effect of the sampling frequency on the identification accuracy. Eventually, the method is verified using the real-time strain data of a continuous steel truss railway bridge. Results show that train speed, axle spacing and gross train weight can be accurately identified in the time domain. However, only the approximate values of the axle weights could be obtained with the updated method. The identified results can provide reliable reference for determining fatigue deterioration and predicting the remaining service life of railway bridges.

Temperature distribution analysis of steel box-girder based on long-term monitoring data

Hao Wang,Qingxin Zhu,Zhongqin Zou,Chenxi Xing,Dongming Feng,Tianyou Tao 국제구조공학회 2020 Smart Structures and Systems, An International Jou Vol.25 No.5

Temperature may have more significant influences on structural responses than operational loads or structural damage. Therefore, a comprehensive understanding of temperature distributions has great significance for proper design and maintenance of bridges. In this study, the temperature distribution of the steel box girder is systematically investigated based on the structural health monitoring system (SHMS) of the Sutong Cable-stayed Bridge. Specifically, the characteristics of the temperature and temperature difference between different measurement points are studied based on field temperature measurements. Accordingly, the probability density distributions of the temperature and temperature difference are calculated statistically, which are further described by the general formulas. The results indicate that: (1) the temperature and temperature difference exhibit distinct seasonal characteristics and strong periodicity, and the temperature and temperature difference among different measurement points are strongly correlated, respectively; (2) the probability density of the temperature difference distribution presents strong non-Gaussian characteristics; (3) the probability density function of temperature can be described by the weighted sum of four Normal distributions. Meanwhile, the temperature difference can be described by the weighted sum of Weibull distribution and Normal distribution.

A Position Detection Method for Dynamic Wireless Inspection Robots Charging

Xue Ming,Yang Qingxin,Zhu Gaojia,Li Longnv 대한전기학회 2022 Journal of Electrical Engineering & Technology Vol.17 No.1

The paper proposes a new structure of the receiving coil, which features horizontal and vertical position detection of inspection robot, which eliminates the system dependence on complex detection control circuit and simplifi es the circuit design of the receiving end. The proposed design obtains the position information by comparing the induced voltage diff erence of the four-coil sets. Besides, the receiving coil is optimized in terms of the shape, dimension and the magnetic shielding structure by fi nite element analysis. Finally, the eff ectiveness of the receiving coil position detection is verifi ed by the experiment with misalignment disturbance. The results illustrate the eff ectiveness of the four-coil system to detect the load position and the position adjustment by the adjustment control system