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      • KCI등재

        Stratigraphic Sequence and Deposition-affected Compressibility of Fine-grained Sediments in the Ancient Yellow River Delta during the Late Pleistocene and Holocene

        Ming-Zhi Zhao,Qiang Luo,Liang-Wei Jiang,Ming Wei 대한토목학회 2019 KSCE JOURNAL OF CIVIL ENGINEERING Vol.23 No.1

        To investigate the stratigraphic sequence in the ancient Yellow River Delta and further discuss the correlation of compressibility of undisturbed soils with depositional environments, two boreholes were drilled at Liyao test site in Cangzhou, Hebei Province, China. Some basic tests regarding to index properties were performed on sediments from one borehole, and oedometer test was conducted for the “undisturbed samples” collected from the other. The stratigraphic sequence in the study area is classified into four depositional systems in terms of sedimentation environment. Evaluation of sample disturbance shows that the “undisturbed samples” for oedometer test are just slightly disturbed in the sampling process. Since overall compressibility can be divided into intrinsic compressibility and additional one, the environmental factors that can affect soil microstructure are closely correlated with additional compressibility. Thus, the influencing mechanism of depositional rate on additional void index ΔIv was investigated quantitatively. Moreover, the relationship between floating range of yield stress and buried depth is established. Then, the additional compressibility of undisturbed samples can be evaluated with depositional rate and buried depth. Finally, the predicted overall compression curve with the proposed method in this study is compared with the measured curve to verify the reasonability and feasibility.

      • KCI등재

        A simple approach to the elasto-plastic coupling analyses of circular tunnels in confining pressure-dependent strain-softening rock masses

        Qiang Zhang,Cheng Li,Qiang Guo,Ming Min,Yanning Wang,Binsong Jiang 한국자원공학회 2017 Geosystem engineering Vol.20 No.5

        The conventional strain-softening behaviors which assume the strength parameters as the functions of the plastic strain have been studied using various methods. However, rock-like materials have also been found to manifest pressure-dependent behavior for both elastic and plastic rock masses. The realization of the radial stress was found to be continuous, and gradually increased from supporting stress to in situ stress for the circular openings under hydrostatic pressure. The radial stress was spaced as numbers of sections, and each annulus was considered as an ideal plastic rock mass. The close-formed analytical solutions of each annulus can be easily obtained. Therefore, using the displacement continuum and stress boundary conditions, the dimensionless radius corresponding to the spaced radius could be derived. The radial stress and plastic shear strain at the inner radius of the outer adjacent annulus were employed to describe the material property evolution law. Then, the radii could be recursively obtained. Finally, for the conventional strain-softening rock masses, the pressure-dependent elastic rock and elasto-plastic coupling strain-softening rock masses were employed to validate the proposed approach. In this study, having completed the above steps, it was concluded that the results were in accordance with the numerical methods.

      • KCI등재

        Purification and Characterization of a Thermostable Laccase from Trametes trogii and Its Ability in Modification of Kraft Lignin

        ( Ming Qiang Ai ),( Fang Fang Wang ),( Feng Huang ) 한국미생물 · 생명공학회 2015 Journal of microbiology and biotechnology Vol.25 No.8

        A blue laccase was purified from a white rot fungus of Trametes trogii, which was a monomeric protein of 64 kDa as determined by SDS-PAGE. The enzyme acted optimally at a pH of 2.2 to 4.5 and a temperature of 70°C and showed high thermal stability, with a half-life of 1.6 h at 60°C. A broad range of substrates, including the non-phenolic azo dye methyl red, was oxidized by the laccase, and the laccase exhibited high affinity towards ABTS and syringaldazine. Moreover, the laccase was fairly metal-tolerant. A high-molecular-weight kraft lignin was effectively polymerized by the laccase, with a maximum of 6.4-fold increase in weight-average molecular weight, as demonstrated by gel permeation chromatography. Notable structural changes in the polymerized lignin were detected by Fourier transform infrared spectroscopy and 1H NMR spectroscopy. This revealed an increase in condensed structures as well as carbonyl and aliphatic hydroxyl groups. Simultaneously, phenolic hydroxyl and methoxy groups decreased. These results suggested the potential use of the laccase in lignin modification.

      • KCI등재

        Controllable synthesis of bowl-shaped porous carbon materials through didodecyldimethylammonium bromide for high performance supercapacitors

        Guo Qiang Zhu,Li Bingyu,Shen Ming,Li Weizheng,Gao Qiang,Xu Guodong 한국화학공학회 2023 Korean Journal of Chemical Engineering Vol.40 No.6

        A series of bowl-shaped porous carbon materials was successfully synthesized by the use of didodecyldimethylammonium bromide as the soft template agent. By controlling the dosage of the soft template agent and the water/ethanol ratio of the solvent, the size and structure of the carbon materials can be precisely controlled. The prepared carbon materials with stacked bowl structure have good specific surface area (1,380.20 m2 g−1), large pore volume (1.27 cm3 g−1) and high heteroatom N doping amount (6.68 at.%). Moreover, electrochemical tests in 6 M KOH demonstrated impressive electrochemical performance, where the specific capacity of the typical materials was measured to be 191.0 F g−1 (at the current density of 1 A g−1), and the capacity retention rate of typical materials was 80% (at the current density of 10 A g−1).

      • Inhibition of Transient Receptor Potential Melastain 7 Enhances Apoptosis Induced by TRAIL in PC-3 cells

        Lin, Chang-Ming,Ma, Ji-Min,Zhang, Li,Hao, Zong-Yao,Zhou, Jun,Zhou, Zhen-Yu,Shi, Hao-Qiang,Zhang, Yi-Fei,Shao, En-Ming,Liang, Chao-Zhao Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.10

        Transient receptor potential melastain 7 (TRPM7) is a bifunctional protein with dual structure of both ion channel and protein kinase, participating in a wide variety of diseases including cancer. Recent researches have reported the mechanism of TRPM7 in human cancers. However, the correlation between TRPM7 and prostate cancer (PCa) has not been well studied. The objective of this study was to investigate the potential the role of TRPM7 in the apoptosis of PC-3 cells, which is the key cell of advanced metastatic PCa. In this study, we demonstrated the influence and potential function of TRPM7 on the PC-3 cells apoptosis induced by TNF-related apoptosis inducing-ligand (TRAIL). The study also found a novel up-regulated expression of TRPM7 in PC-3 cells after treating with TRAIL. Suppression of TRPM7 by TRPM7 non-specific inhibitors ($Gd^{3+}$ or 2-aminoethoxy diphenylborate (2-APB) ) not only markedly eliminated TRPM7 expression level, but also increased the apoptosis of TRAIL-treated PC-3 cells, which may be regulated by the phosphatidylinositol 3-kinase/protein kinase B (PI3K/AKT) signaling pathway accompany with up-regulated expression of cleaved Caspase-3, (TRAIL-receptor 1, death receptors 4) DR4, and (TRAIL-receptor 2, death receptors 5) DR5. Taken together, our findings strongly suggested that TRPM7 was involved in the apoptosis of PC-3 cells induced by TRAIL, indicating that TRPM7 may be applied as a therapeutic target for PCa.

      • Price Learning Based Load Distribution Strategies for Demand Response Management in Smart Grid

        Qiang Tang,Ming-zhong Xie,Kun Yang,Yuan-sheng Luo,Ping Li 보안공학연구지원센터 2016 International Journal of Smart Home Vol.10 No.11

        In this paper, a Price learning based Load Distribution Strategy (PLDS) is proposed at first. In PLDS model, Smart Power Service, Utility Company and History Load Curves are included, and by considering both the average electricity consumption cost and the average electricity consumption habit, we proposed a convex optimization model to solve the model. In order to accelerate the convergence of PLDS, a price learning mechanism is proposed, which learns a price curve according to the history price data, and predicts price as a learned price for the next iteration. The optimization cycle of PLDS is one day or 24 hours, and in order to further improve the peak shaving performance, an extended version of PLDS named PLRS (Price learning based Load Redistribution Strategy) is proposed, whose optimization cycle length is 1 hour. The optimization models of PLDS and PLRS are the same, and the differences between them are the optimization cycle and the constraint conditions. In the simulation, we compared the convergence performance, peaking shaving performance and total cost among PLDS, PLRS and other strategy ODC in reference [11], and we found that the convergence performances of PLDS and PLRS are both better than that of ODC. The peak shaving performance of PLRS is better than that of ODC in the long term, and the total cost of PLRS is very close to that of ODC.

      • KCI등재

        On time reversal-based signal enhancement for active lamb wave-based damage identification

        Qiang Wang,Shenfang Yuan,Ming Hong,Zhongqing Su 국제구조공학회 2015 Smart Structures and Systems, An International Jou Vol.15 No.6

        Lamb waves have been a promising candidate for quantitative damage identification for various engineering structures, taking advantage of their superb capabilities of traveling for long distances with fast propagation and low attenuation. However, the application of Lamb waves in damage identification so far has been hampered by the fact that the characteristic signals associated with defects are generally weaker compared with those arising from boundary reflections, mode conversions and environmental noises, making it a tough task to achieve satisfactory damage identification from the time series. With awareness of this challenge, this paper proposes a time reversal-based technique to enhance the strength of damage-scattered signals, which has been previously applied to bulk wave-based damage detection successfully. The investigation includes (i) an analysis of Lamb wave propagation in a plate, generated by PZT patches mounted on the structure; (ii) an introduction of the time reversal theory dedicated for waveform reconstruction with a narrow-band input; (iii) a process of enhancing damage-scattered signals based on time reversal focalization; and (iv) the experimental investigation of the proposed approach to enhance the damage identification on a composite plate. The results have demonstrated that signals scattered by delamination in the composite plate can be enhanced remarkably with the assistance of the proposed process, benefiting from which the damage in the plate is identified with ease and high precision.

      • KCI등재

        Long noncoding RNA NEAT1 suppresses hepatocyte proliferation in fulminant hepatic failure through increased recruitment of EZH2 to the LATS2 promoter region and promotion of H3K27me3 methylation

        Qiang Wang,Lian Liu,Sheng Zhang,Yingzi Ming,Shu Liu,Ke Cheng,Yujun Zhao 생화학분자생물학회 2020 Experimental and molecular medicine Vol.52 No.-

        Fulminant hepatic failure (FHF) refers to the rapid development of severe acute liver injury with impaired synthetic function and encephalopathy in people with normal liver or well-compensated liver disease. This study aimed to investigate the function of long noncoding RNA (lncRNA) nuclear-enriched abundant transcript 1 (NEAT1) on the proliferation and apoptosis of hepatocytes in FHF. Our results revealed that lncRNA NEAT1 was upregulated in cell and animal models of FHF induced by D-galactosamine (D-GalN)/lipopolysaccharide (LPS). Overexpression of lncRNA NEAT1 resulted in elevated hepatocyte apoptosis and impaired large tumor-suppressor kinase 2 (LATS2) expression and proliferation. Functional analysis revealed that knockdown of lncRNA NEAT1 inhibited hepatocyte apoptosis and induced proliferation both in vitro and in vivo. RNA immunoprecipitation and chromatin immunoprecipitation assays demonstrated that lncRNA NEAT1 recruited enhancer of zeste homolog 2 (EZH2) to the LATS2 promoter and repressed LATS2 expression. Furthermore, ectopic expression of LATS2 increased proliferation and inhibited hepatocyte apoptosis by regulating the Hippo/Yes-associated protein (YAP) signaling pathway. Taken together, our findings indicate that lncRNA NEAT1 might serve as a novel target for FHF therapy due to its regulation of H3K27me3 methylation-dependent promotion of LATS2.

      • KCI등재

        Feedforward and Feedback Compound Control of Vibration Displacement for a Continuous Casting Mold Driven by a Servo Motor

        Qiang Li,Yi-ming Fang,Jian-Xiong Li,Wen-jian Zhang 제어·로봇·시스템학회 2020 International Journal of Control, Automation, and Vol.18 No.12

        In view of the fact that the vibration displacement system of continuous casting mold driven by a servo motor requires the motor rotate in a certain fixed direction, a compound control scheme combining feedforward and feedback control is proposed in this paper. In controller designing, there are mainly two issues to be considered: i) constraint condition that the servo motor rotates in a fixed direction while the mold vibrates in a periodic form. ii) uncertainties caused by time-varying load and mechanical factors, such as mechanical zero initial deviation and machining precision. As to the system uncertainties and the periodic vibration displacement of mold, proportional-integral (PI) controller combined with the repetitive control method are used to realize displacement tracking and improve the tracking performance. A feedforward control algorithm consisting of the reference mold displacement and its first derivative is adopted to solve the constraint condition. Finally, some simulation results show the feasibility of the proposed algorithm for the constraint condition and system uncertainties. Additionally, a typical industry mold vibration system driven by a servo motor is conducted to show the effectiveness of the proposed control scheme.

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