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      • KCI등재

        Characterization of a novel variant HMW‐glutenin gene from Elymus canadensis

        Qian‐Tao Jiang,Yu‐Ming Wei,Tao Liu,Ji‐Rui Wang,Zhi‐En Pu,Xiu‐Jin Lan,You‐Liang Zheng,Zhen‐Xiang Lu 한국유전학회 2010 Genes & Genomics Vol.32 No.4

        High molecular weight (HMW) glutenin subunits (GS) play a key role in the determination of end‐use quality of wheat and other cereal crops. In this study, we report the isolation and characterization of both promoter region and ORF of novel HMW‐GS allele 1St1.3 from a perennial Triticeae species,Elymus canadensis. The amino acid (AA) sequences of E. canadensis 1St1.3 were deduced as 434 aa. Its protein primary structure comprises a signal peptide with a conserved N‐terminal domain, a central repetitive domain and a C‐terminal domain. E. canadensis 1St 1.3 possesses several distinct characteristics which are different from those of wheat HMW‐GSs. The N‐terminal domains of E. canadensis 1St 1.3 resemble that of y‐type subunits, while their C‐terminal domains are more similar to x‐type subunits. The deletion of 85 bp fragment has been observed in promoter region of 1St 1.3, however which has not interrupted the expression of this gene. Our results indicate that 1St 1.3 is novel HMW‐GS variants which will be valuable for enhancing our understanding of structural differentiation and the evolutionary relationship among HMW‐GSs in Triticeae species.

      • KCI등재

        총성 없는 전쟁터 : 1950년대 중국에서의 북한문학 번역장

        등천 ( Deng¸ Qian ) 민족문학사학회·민족문학사연구소 2020 민족문학사연구 Vol.74 No.-

        본고에서는 1950년부터 1960년까지 중국에서 번역된 북한문학 작품들을 전반적으로 검토함으로써 1950년대 중국에서 북한문학 번역의 전모, 특징과 의의를 살펴보고 아울러 번역과 전쟁의 관계를 조명했다. 우선, 평화 시기와 달리 1950년대에 번역된 북한문학 작품들은 강한 시효성, 호소력과 대중성을 드러냈다. 장르별로 보면 르포르타주, 시가, 아동문학, 북한, 희곡 등을 폭넓게 번역함으로써 다양한 독자층을 최대한 포섭했다. 주제별로 보면 조선 인민의 수난과 투쟁, 미 제국주의의 침략과 폭행, 중· 조(中朝) 인민의 전우애를 형상화한 작품들을 번역함으로써 동맹국으로서의 상상된 공동체를 구축했다. 1950년대 북한문학 번역의 또 다른 특징은 동맹국 사이의 협업 번역으로 꼽힌다. 중국측에서는 일본어와 러시아어에 능통한 베테랑 번역자, 대학에 재직 중인 한인 교원, 한반도에서 귀국한 화교(華僑) 등 다양한 번역진을 조직하여 북한문학을 적극적으로 도입했다. 북한 측에서는 중국어에 능통한 번역자를 동원하여 자국문학을 계획적으로 중국에 수출했다. 6·25전쟁의 군사적 충돌과 이데올로기 간의 대치는 번역의 장에서 작용하여 문학 텍스트에 교묘하게 녹아들었다. 북한 작가 이북명의 소설 「악마」는 두 차례의 중국어 번역을 통해 각기 다른 양상으로 드러났다. 베이징 대학 한인 교원 마초군의 충실한 번역태도와 달리, 『인민문학』판 역본에는 편집자가 교묘한 첨삭을 통해 ‘사랑’과 ‘원한’의 이원적 감성 구조를 부각시키는 한편 전쟁으로 인해 조성된 부정적 감정을 대폭 은폐시켰다. 요컨대 1950년대 북한문학 번역장에서 선택과 배제, 강조와 은폐의 메커니즘이 작동하여 전쟁의 ‘실상’을 재구성하고 냉전의 심리적인 토대를 구축했다. 이런 측면에서 보면 1950년대 중국에서 활발하게 펼쳐진 북한문학 번역장은 이데올로기 투쟁의 ‘총성 없는 전쟁터’라 할 수 있다. In the early period after the foundation of the People’s Republic of China translation was institutionalized and entailed a political effect, which demonstrated in national translation program. It laid an institutional foundation for the translation of North Korean literature during the War to Resist U.S. Aggression and Aid Korea. The translation of North Korean literature in the 1950s was not only second only to Soviet literature in scale and quantity, but also reflected the publicity and propaganda function of wartime translation, thus presenting a special translation ecology. The paper, based on a survey of translation works of North Korean published in China from 1949 to 1960, through quantitative analysis and text reading, reveals three features of wartime translation. Firstly, the political orientation of the selection of source texts is prominent as well as popular. Secondly, import national translation by China and export national translation by DPRK, direct and indirect translation, foreign and local translators coexist simultaneously, which constitutes a pluralistic translation model. Thirdly, rewriting strategy is adopted to strengthen the Cold War mentality and weaken the negative emotions caused by the war, in order to demonstrate the justice of the war and prove the legitimacy of the People’s Republic of China. The authors contend that the translation of North Korean literature in the 1950’ subjectively demonstrated the wartime demands of the National Translation Program, and objectively participated in the construction of the literary genealogy of the War to Resist U.S. Aggression and Aid Korea.

      • How Does Power Distance Belief Impact Variety-Seeking Behavior? A Moderated Mediation Approach

        Qi An,Jinzhe Yan,Yeonggil Kim The International Academy of Global Business and T 2023 The International Academy of Global Business and T Vol.19 No.6

        Purpose - This research aims to enhance knowledge of variety-seeking behavior by establishing a novel antecedent based on consumer internal characteristics instead of external stimuli. The report also argues that the insights gleaned can illuminate a method to analyze consumer decision-making based on intrinsic motivation. This study evaluated a potential connection between power distance belief and variety-seeking behavior. This study evaluates variety-seeking behavior by brand, color, taste, and fashion preferences. Varietyseeking behavior is essential in understanding consumer choices. This paper aims to find the mechanism of the relation between power distance belief with variety-seeking behavior, along with the boundary condition of variety-seeking behavior. Design/Methodology/Approach - This study performed three experiments for measurement and hypothesis testing. This study employed analysis of variance, multiple regression, and process macro for moderated mediation testing with SPSS 28.0. Findings - This research confirms the prediction that higher power distance beliefs tend to elect variety through Study 1, and that risk-seeking mediates the moderation of boredom between power distance belief and variety-seeking behavior through Study 2. The authors conclude by discussing the implications for the application of the theory for managers. Research Implications - These contributions provide professionals with practical consequences for a variety of marketing tasks, such as market segmentation, product extension and innovation, and advertising guides.

      • The ERCC1 C118T Polymorphism Predicts Clinical Outcomes of Colorectal Cancer Patients Receiving Oxaliplatin-Based Chemotherapy: a Meta-analysis Based on 22 Studies

        Qian, Ying-Ying,Liu, Xin-You,Wu, Qian,Song, Xian,Chen, Xiao-Feng,Liu, Yi-Qian,Pei, Dong,Shen, Li-Zong,Shu, Yong-Qian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.19

        Background: Although the predictive value of the excision repair cross-complementing group 1 (ERCC1) C118T polymorphism in clinical outcomes of patients with colorectal cancer (CRC) receiving oxaliplatin-based chemotherapy has been evaluated in numerous published studies, the conclusions are conflicting. Therefore, we performed the present meta-analysis to determine the precise role of the ERCC1 C118T polymorphism in this clinical situation and help optimize individual chemotherapy. Materials and Methods: A multiple search strategy was used to identify eligible studies. Pooled odds ratios (ORs) and their 95% confidence intervals (CIs) were used to estimate objective response and oxaliplatin-induced toxicity, with hazard ratios (HRs) with 95%CIs for progression-free survival (PFS) and overall survival (OS). Results: A total of 22 studies including 2,846 CRC patients were eligible in the analysis. Overall, no significant correlation was found between the ERCC1 C118T polymorphism and objective response to oxaliplatin-based chemotherapy, in all patients or in the Asian and Caucasian subgroups. However, the pooled analysis showed that the PFS and OS were significantly shorter in patients who carried T/T or T/C genotypes of ERCC1 C118T as compared to the C/C genotype. On stratified analysis by ethnicity, the ERCC1 118T allele was associated with a favorable prognosis in Caucasians (PFS, HR=0.58, 95%CI: 0.24-1.44; OS, HR=0.38, 95%CI: 0.22-0.64) but an unfavorable prognosis in Asians (PFS, HR=2.49, 95%CI: 1.87-3.33; OS, HR=2.63, 95%CI: 1.87-3.69) based on a dominant model. In addition, we failed to find a statistically significant impact of ERCC1 C118T polymorphism on oxaliplatin-induced toxicity. Conclusions: The ERCC1 C118T polymorphism may have prognostic value in patients with CRC undergoing oxaliplatin-based chemotherapy.

      • KCI등재

        Almost Sure Stability of Dual Switching Continuous-time Nonlinear System With Deterministic and Stochastic Subsystems

        Qian-qian Mu,Fei Long,Qi-xiang Wang,Lang Zhang,Li-po Mo 제어·로봇·시스템학회 2024 International Journal of Control, Automation, and Vol.22 No.1

        In this paper, the almost surely globally asymptotical stability and the almost surely exponential stability for dual switching continuous-time nonlinear system are investigated by using the probability analysis method and stochastic Multi-Lyapunov function, respectively. Different from the previous research results, it is the first time that dual switching continuous-time nonlinear system is used as a study object to investigate its switching stability. Then, the probability analysis method is used to overcome the deficiency that the ergodicity no longer holds due to the variable transition rate of Markov process. Some sufficient conditions for the globally asymptomatic stability almost surely and the almost surely exponential stability of dual switching continuous-time nonlinear system are given under the pre-designed deterministic switching strategy. Finally, two numerical examples are provided to verify the effectiveness of the proposed approach.

      • The XPD Lys751Gln Polymorphism has Predictive Value in Colorectal Cancer Patients Receiving Oxaliplatin-Based Chemotherapy: a Systemic Review and Meta-analysis

        Qian, Ying-Ying,Liu, Xin-You,Pei, Dong,Xu, Jia-Li,Shen, Hua,Chen, Xiao-Feng,Liu, Yi-Qian,Shen, Li-Zong,Shu, Yong-Qian Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.22

        Background: The predictive value of the xeroderma pigmentosum group D (XPD) Lys751Gln polymorphism regarding clinical outcomes of patients with colorectal cancer (CRC) receiving oxaliplatin-based chemotherapy has been evaluated in numerous published studies, but the results remain inconclusive. Therefore, we performed a meta-analysis to determine the precise role of the XPD Lys751Gln polymorphism in this clinical situation and optimize individual chemotherapy. Materials and Methods: A multiple search strategy was used to identify eligible studies. Pooled odds ratios (ORs), generalized odds ratio (ORG) and their 95% confidence intervals (CIs) were used to estimate the objective response, while hazard ratios (HRs) with 95%CIs were used for progression-free survival (PFS) and overall survival (OS). Results: A total of 17 studies including 2,286 patients met the inclusion criteria. Overall, the XPD 751Gln allele was associated with a non-significant reduced objective response to oxaliplatin-based chemotherapy in all patients or in the Asian and Caucasian subgroups. However, poor PFS and OS of CRC patients treated with oxaliplatin-based regimens were significantly related to the XPD 751Gln allele in the dominant model (PFS: HR=2.10, 95%CI: 1.65-2.67; OS: HR=3.18, 95%CI: 1.57-6.47). On stratified analysis by ethnicity, these relationships were more pronounced in Asians (PFS: HR=2.49, 95%CI: 1.79-3.47; OS: HR=5.25, 95%CI: 3.46-7.94) than in Caucasians (PFS: HR=1.73, 95%CI: 1.22-2.46; OS: HR=1.78, 95%CI: 1.06-2.99). Conclusions: The XPD Lys751Gln polymorphism may have prognostic value in patients with CRC undergoing oxaliplatin-based chemotherapy.

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