Involvement of MicroRNA-198 Overexpression in the Poor Prognosis of Esophageal Cancer

Qi, Bo,Yao, Wen-Jian,Zhao, Bao-Sheng,Qin, Xiu-Guang,Wang, Yi,Wang, Wen-Ju,Wang, Tian-Yun,Liu, Shang-Guo,Li, Han-Chen Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.9

Objective: This study aimed to investigate whether the miR-198 expression level is related to clinicopathological factors and prognosis of esophageal cancer. Methods: MicroRNA was extracted from esophageal cancer patients who underwent surgery for assessment using the Taqman@ MicroRNA assay. The correlation between miR-198 expression and clinicopathological features was analyzed, and the significance of miR-198 as a prognostic factor and its relationship with survival was determined. Results: MicroRNA-198 (miR-198) expression was higher in patients with poor prognosis than those with good prognosis (P<0.05). Kaplan-Meier analysis results showed that the miR-198 expression level had a significant correlation with survival time (P=0.030) and that patients with a higher expression of miR-198 had a shorter survival time. Cox multi-factor model analysis showed that patient prognosis (P=0.014), tumor length (P=0.040) and expression (P=0.012), and survival time had a significant correlation; the corresponding risks were 7.268, 1.246, and 3.524, respectively. Conclusion: miR-198 overexpression is involved in the poor prognosis of esophageal cancer and can be used as a biomarker for selection of cases requiring especial attention.

Correlation of Contrast-Enhanced Ultrasonographic Features with Microvessel Density in Papillary Thyroid Carcinomas

Zhou, Qi,Jiang, Jue,Shang, Xu,Zhang, Hong-Li,Ma, Wen-Qi,Xu, Yong-Bo,Wang, Hua,Li, Miao Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.17

Background: The purpose of this study was to investigate the correlation of contrast-enhanced ultrasonographic (CEUS) features with microvessel density (MVD) in papillary thyroid carcinomas (PTCs). Materials and Methods: Contrast-enhanced ultrasonography (CEUS) was performed in 62 patients (17 men and 45 women) with PTC. Tomtec software was applied to analyze the time intensity curve of CEUS. Immunohistochemistry was performed to evaluate the level of MVD in papillary thyroid carcinoma. Then the relationship between quantitative feature and the level of MVD was analyzed using SPSS 16.0 software. Results: The mean peak intensity of PTC tissues was lower than that of peripheral thyroid parenchyma ($61.9{\pm}11.8%$ vs 100%, p<0.05). The MVDs of CD34 and CD31 antibodies staining were $38.0{\pm}6.1$ and $37.9{\pm}5.1$ respectively in 62 PTC samples. A significantly positive correlation was observed between peak intensity and MVD in PTC tissues ($P_{CD34}$<0.01, $r_{CD34}$=0.838, $P_{CD31}$<0.01, $r_{CD31}$=0.837). Conclusions: The peak intensity in CEUS could reflect the MVD in PTC tissues. Therefore, quantification of CEUS seems to be helpful for assessment of MVD in PTC tissues.

Enhancement of Virus-induced Gene Silencing in Tomato by Low Temperature and Low Humidity

Da-Qi Fu,Ben-Zhong Zhu,Hong-Liang Zhu,Hong-Xing Zhang,Yuan-Hong Xie,Wei-Bo Jiang,Xiao-Dan Zhao,Yun-Bo Luo 한국분자세포생물학회 2006 Molecules and cells Vol.21 No.1

Virus-induced gene silencing (VIGS) is an attractive reverse-genetics tool for studying gene function in plants. We showed that silencing of a phytoene desaturase (PDS) gene is maintained throughout TRV-PDSinoculated tomato plants as well as in their flowers and fruit and is enhanced by low temperature (15°C) and low humidity (30%). RT-PCR analysis of the PDS gene revealed a dramatic reduction in the level of PDS mRNA in leaves, flowers and fruits. Silencing of PDS results in the accumulation of phytoene, the desaturase substrate. In addition, the content of chlorophyll a, chlorophyll b and total chlorophyll in the leaves of PDS-silenced plants was reduced by more than 90%. We also silenced the LeEIN2 gene by infecting seedlings, and this suppressed fruit ripenning. We conclude that this VIGS approach should facilitate large-scale functional analysis of genes involved in the development and ripening of tomato.

Taxonomic Notes of Pyralinae (Lepidoptera, Pyraloidea, Pyralidae) in NE China

Mu-Jie Qi,Yong-Don Ju,Xuan-Vi Le,Bo-Sun Park,Hee-Jo Lee,Min-Seon Kim,Yang-Seop Bae 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.10

Pyralinae are one of the largest subfamilies belonging to Pyralidae, which comprises about 900 species of 217 genera in the world, and 150 species belonging to 32 genera are recorded in China (Li houhun, 2009). This subfamily are characterized by the following characteristics: head rounded, chaetosemata present, proboscis developed. Labial palpus porrect or upturned. Maxillary palpus small. Forewing colorful, from narrow to wide, antemedial line and postmedial line present and distinct. Hindwing color simple. Male genitalia with broad uncus, gnathos developed, slim, tip of gnathos sharp or hooked; tegument sclerotized, valve simple with various shape; juxta elliptical or rounded, aedeagus slender, cornutus present or absent. Female genitalia with small papillae anales, corpus bursae oval, signum present or absent. Liaoning Province is located in the southern part of NE China, the area of Liaoning is 146,900 km² and it is bounded on the south by the Yellow sea, on the southeast by North Korea, on the north by Jilin Province, and on the west by Inner Mongolia and Hebei Province. The mean annual temperature is 7-11℃, the mean annual precipitation is 600-1100 mm in northeast part, but 400 mm in west part. Liaoning Province is an important area for forest and agriculture, accordingly, to survey the diversity of Pyralinae is of great significance for systematic study in Liaoning Province. In this study, our materials examined come from the collection of Northeast forestry University from 2006-2010, and the collection of Incheon University from 2010-2012. Finally, we identified 11 species belonging to 8 genera, of them, 1 species are the first time reported in China, and 6 speices are the first time reported in Liaoning Province.

Taxonomic Study of Spilomelinae (Lepidoptera, Pyraloidea, Crambidae) in Cambodia

Mu-Jie Qi,Yong-Don Ju,Xuan-Vi Le,Bo-Sun Park,Hee-Jo Lee,Min-Seon Kim,Yang-Seop Bae 한국응용곤충학회 2012 한국응용곤충학회 학술대회논문집 Vol.2012 No.05

As one of the subfamilies of Crambidae, Spilomelinae comprises about 3767 species in the world (Solis and Maes, 2002), and this subfamily is characterized by the following characteristics: Chaetosema absent, antenna filiform, labial palpus and proboscis well developed, forewing with R3 and R4 stalk at base, or R2, R3 and R4 stalked, but R5 single, 2A and 1A form a loop; hindwing Sc+R1 stalked with Rs; male genitalia with gnathos absent or rudimentary, but uncus well developed, shape various. Cambodia is a country that bordered by Thailand, Laos, Vietnam and Gulf of Thailand in Southeast Asia. The total area is 181,035 km2. It is also a country with high biodiversity, of them, 212 mammal species, 536 bird species, 240 reptile species, 850 freshwater fish species, and 435 marine fish species, but only a few studies about the fauna of Lepidoptera there. Accordingly, to survey the diversity of Lepidoptera is of great significance for systematic study in Cambodia. In this research, we started our survey from 2009, up to now, we got numerous Pyraloidea from Cambodia, in this study, we identified 48 species belonging to 36 genera of Spilomelinae, most of them are reported for the first time in Cambodia, and some specimen could not be identified which we will report in future. All the materials examined come from the collection of University of Incheon.

Two Species of Phycitinae (Lepidoptera, Pyralidae) new to Korea

Mu-Jie Qi,Bayarsaikhan Ulziijargal,Bo-Sun Park,Sol-Moon Na,Jae-Won Kim,Yang-Seop Bae 한국응용곤충학회 2014 한국응용곤충학회 학술대회논문집 Vol.2014 No.10

The subfamily of Phycitinae is one of the largest groups in family Pyralidae, as Solis and Mitter (1992) estimated, about 4000 species in the world. The Phycitinae are characterized by the following characteristics: forewings long and narrow, with 11 veins or less, R3 and R4 stalked at base or fused completely, both male and female with only one frenulum; gnathos usually rod-shaped or coniform; valva usually hairy, with well-developed costa, sacculus well-sclerotized, shorter than valva, transtilla free or connected at top, juxta and vinculum U-shaped; most of male with culcita; ductus bursae usually from corpus bursae. The larvae of phycitinae are leaf rollers, leaf bores and leaf miners, also they are predators and products pests. Their distribution is throughout the world (Munroe and Solis, 1999). Leech and South (1901) first reported 3 species of Phycitini from the Korean Peninsula; after that, several researchers respectively made contributions to the fauna of Korean Phycitinae. Until 2008, Bae et al. recorded 79 species from South Korea. Currently, Qi and Bae (2014) added two more phycitinae species for Korea. In the present study, we identified two more Phycitinae species which are newly recorded from Korea. The morphology of adults and genitalia are redescribed and illustrated, the specimens examined are deposited in Incheon National University, Korea.

Research in Equalizing Charging Control Strategy in Li-ion Power Battery

Bo Wu,Hang Liu,Haiying Wang,Zongru Zhou,Qi Fan 보안공학연구지원센터 2013 International Journal of Control and Automation Vol.6 No.2

A System Performance Estimation Model for Cassandra Database

Bo-Qian Wang,Qi Yu,Xin Liu,Li Shen,Zhi-ying Wang 보안공학연구지원센터 2016 International Journal of Database Theory and Appli Vol.9 No.3

Cassandra database system is one of the universal databases. To achieve high performance, we should allocate memory space rationally according to actual demands. Otherwise, it will influence reading and writing performance. Actually, we always allocate memory space according to experience and repeated attempts which usually won’t give us the best answer. To solve this problem, firstly we analyze the reading and writing processing of the Cassandra database and find out the corresponding memory space which will influence system performance. Secondly, we build up a relationship model between system performance and memory allocation and name it as The Memory Model of Reading and Writing Performance. We have already applied the relationship model to real database servers to guide memory allocation and performance evaluation. Simulation results show that this memory model could well describe the quantization relationship of memory space and system performance.

Some inequalities of Hermite-Hadamard type for geometrically p-convex functions

Bo-Yan Xi,Feng Qi 장전수학회 2016 Advanced Studies in Contemporary Mathematics Vol.26 No.1

In the paper, the authors introduce a concept of geometrically P- convex functions and establish some new Hermite-Hadamard type inequalities for this kind of functions.

Research on Friction Characteristics of AlCrN and TiAlSiN Coatings and Properties of Coated Tools

Qi-Bin Yue,Hui-Bo He,Hua-Ying Li,Jun Zhang,Yuan-ming Li,Lu Ma 한국정밀공학회 2019 International Journal of Precision Engineering and Vol.20 No.9

AlCrN and TiAlSiN coatings were deposited on the surface of 30CrMnSi steel and cemented carbide YT15 by multi-arc ion plating technique. A scanning electron microscopy was used to observe the surface morphologies of both coatings. The reciprocating sliding tests of AlCrN and TiAlSiN coating were performed to investigate the friction coefficients and the wear mechanisms of both coatings were analyzed as well. Dry machining tests on 30CrMnSi hardened steel were carried out with the AlCrN and TiAlSiN coated tools on a CA6140A lathe. The effects of cutting speed on cutting forces and cutting temperatures of AlCrN and TiAlSiN coated tools were obtained and analyzed. The microcosmic micrographs of wear areas of both coated tools were observed and investigated by scanning electron microscope and energy dispersive spectrum. The results show that the hardness and bonding strength of AlCrN coating are higher than that of TiAlSiN coating, while the friction coefficient of AlCrN coating is lower than that of TiAlSiN coating. Both the cutting force and cutting temperature of AlCrN coated tool are lower than TiAlSiN coated tool. The time required for the bluntness of the AlCrN coated tool is approximately 33.3% longer than that of the TiAlSiN coated tool, and the main wear mechanisms of both tools are mainly crater wear, diffusion wear and oxidation wear.