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도로점용공사장 교통소통대책 도입 필요성 및 효과 분석 연구
박평근(Park, Pyungkeun),강진동(Kang, Jindong),최정규(Choe, Jeong-Gyu),김종혁(Kim, Jonghyuk) 대한교통학회 2015 대한교통학회 학술대회지 Vol.73 No.-
본 연구에서는 현재 운영되고 있는 서울시 공사중 교통소통대책 수립에 대한 전반적인 내용을 살펴보고 사례를 통해 도로점용공 사장 교통소통 대책의 효과분석 및 필요성을 제시하고 있다. 이를 위해 이 연구는 도로점용공사장 교통소통대책의 효과분석을 위해 편익·비용(Benefit Cost) 분석 방법으로 서울시의 도로점용공사중 하수도 공사와 지하철 역사 혼잡도 개선 공사 2건에 대해 효과분석 을 실시하였다. 그 결과 일일비용으로 변경하여 절감편익과 합산한 결과 지하철역 혼잡도 개선공사는 일일비용이 절감되는 것으로 나와 도로점용공사장 교통소통대책 자문회의 심의 효과가 있는 것으로 나타났다. 따라서, 공사중 교통소통대책은 도로를 점용할 때 발생할 수 있는 제반 교통소통상의 문제를 사전에 검토하고 교통혼잡을 최소화하기 위해 필요하다.
Basma 잎담배의 Vacuum Tobacco Conditioning (VTC)와 Compressed Tobacco Conditioning(CTC)처리에 따른 향기성분분석
명평근,김천석 충남대학교 약학대학 의약품개발연구소 1989 藥學論文集 Vol.5 No.-
Volatile flavors of Basma tobacco by Vacuum Tobacco Conditioning (VTC) and Compressed Tobacco Conditioning (CTC) treatments were analyzed by Gas Chromatogaphy. The Results obtained from this experiment are as following: 1. As Basma tobacco leaves were processed by VTC treatment, the amounts of volatile components of benzyl alcohol, phenyl acetaldehyde and dibutyl phthalate were reduced, while that of damascone was increased. 2. After CTC treatment the reduced volatile flavors of Basma tobacco leaves were benzyl alcohol, 7-undecane+Linalool, 2-phenylethyl alcohol, thymol, dibutyl phthalate, n-pentacosane and n-hexacosane, while the increasing components were furfural, phenyl acetate and n-eicosane. 3. In order to minimize the change of flavoring components of Basma tobacco leaves during the preconditioning, we should plan to improve the working method to minimize the heating and steam flow and to treat at the lower temperature and within short time.
Burley와 황색종 잎담배들의 Toast과정 중 Pyrazine의 생성
명평근,김천석 충남대학교 약학대학 의약품개발연구소 1989 藥學論文集 Vol.5 No.-
The change of volatile flavoring components and the formation of pyrazine during toasting condition of Burley and Flue-cured tobacco leaves in the manufacturing process were analyzed by Gas Chromatograph. The results are as following: 1. After the toasting treatment of Burley 21 and Flue-cured tobacco leaves, the amounts of pyrazine and its derivatives, furfural and its derivatives, benzaldehyde, maltol, beta-Ionone and beta-Ionone epoxide were reduced, while the increasing components were hexanol, terpineol and neophytadiene. 2. The optimum condition of Burley 21 tobacco leaves on the toasting treatment was that the addition of sucrose was 4~7% and that of the formation of pyrazine was 125℃ for the treatment temperature and 5 minutes for the treatment time.
배기환,김봉희,명평근,변재화 충남대학교 약학대학 의약품개발연구소 1990 藥學論文集 Vol.6 No.-
The isolation and identification of an antibacterial component, from the leaves of Liriodendron tulipifera. K. Kotch against a cariogenic bacterium Streptococcus mutans OMZ 176, were carried out for developing of anticariogenic agents. The bioactive component was elucidated as β-liriodenolide, which was isolated newly from the leaves of L.tulipifera. The minimal inhibitory concentration (MIC) of β-liriodenolide was 100 ㎍/㎖ and the antibacterial activity was stronger than that of berberine. β-Liriodenolide inhibited β-lactamase activity, 50. 100 and 200 μM β-liriodenolide did β-lactamase activity as 0.7, 3.5 and 19.7%, respectively. The toxicity of β-liriodenolide was not found with the method of photohemolysis.
tert-Butyl Hydroperoxide로부터 유도된 산화 스트레스에 대한 Catechol의 보호효과
신동희,남진경,박창식,고지훈,명평근 충남대학교 약학대학 의약품개발연구소 2009 藥學論文集 Vol.24 No.-
This study was to evaluate the protective effects of the catechol compound of Camellia japonica leaf on the tert-butyl hydroperoxide(t-BHP) induced oxidative injury in mice. To examine the in vitro effects of catechol on oxidative stress, human hepatoma cell line, Hep G2 was used and the tetrazolium dye colorimetric test(3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide(MTT) assay was employed to monitor cytotoxicity. The in vivo study was carried out by administering catechol(0.01, 0.1, 1mg/kg b.w.) by orally for 5 days before a single dose of t-BHP(1.5 mmol/kg i.p.). When the concentration of catechol pretreatment was increased, the liver MDA level was decreased. It was shown that catechol treatment did not alter the serum levels of the hepatic enzyme markers such as aspartate amino-transferase(AST) and alanine aminotransferase(ALT). Next, expression of antioxidant enzymes in liver after catechol treatment were studied using RT-PCR. The liver mRNA expression for antioxidant enzymes; such as Cu/Zn SOD or extracellular SOD were increased after catechol treatment group. These results suggest that catechol may have a potential role in the prevention of oxidative damage of liver in living organism.