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Export-led Growth in South Asia: A Panel Cointegration Analysis
Purna Chandra Parida,Pravakar Sahoo 한국국제경제학회 2007 International Economic Journal Vol.21 No.2
In this paper, we attempt to examine the export-led and manufacturing export-led growth hypothesis for four South Asian Countries viz., India, Pakistan, Bangladesh and Sri Lanka, using Pedronis panel cointegration technique for the period 1980-2002. In this context we estimate growth accounting equations to investigate the impact of exports, manufacturing exports and, other important physical and human capital variables on both total GDP and non-export GDP. The study finds long-run equilibrium relationship between GDP (and non-export GDP) and exports along with other variables supporting export-led growth hypothesis. The results also substantiate the existence of manufacturing export-led growth hypothesis. Further, we find that export, fixed capital formation, public expenditure on health and education have statistically significant coefficients re-emphasizing the importance of these variables for higher economic growth.
STAT6 and PARP Family Members in the Development of T Cell-dependent Allergic Inflammation
Purna Krishnamurthy,Mark H. Kaplan 대한면역학회 2016 Immune Network Vol.16 No.4
Allergic inflammation requires the orchestration of altered gene expression in the target tissue and in the infiltrating immune cells. The transcription factor STAT6 is critical in activating cytokine gene expression and cytokine signaling both in the immune cells and in target tissue cells including airway epithelia, keratinocytes and esophageal epithelial cells. STAT6 is activated by the cytokines IL-4 and IL-13 to mediate the pathogenesis of allergic disorders such as asthma, atopic dermatitis, food allergy and eosinophilic esophagitis (EoE). In this review, we summarize the role of STAT6 in allergic diseases, its interaction with the co-factor PARP14 and the molecular mechanisms by which STAT6 and PARP14 regulate gene transcription.
Identification of 1,3,6,8- Tetrahydroxynaphthalene Synthase (ThnA) from Nocardia sp. CS682
( Purna Bahadur Poudel ),( Rubin Thapa Magar ),( Adzemye Fovennso Bridget ),( Jae Kyung Sohng ) 한국미생물생명공학회 2023 Journal of microbiology and biotechnology Vol.33 No.7
Type III polyketide synthase (PKS) found in bacteria is known as 1,3,6,8-tetrahydroxynaphthalene synthase (THNS). Microbial type III PKSs synthesize various compounds that possess crucial biological functions and significant pharmaceutical activities. Based on our sequence analysis, we have identified a putative type III polyketide synthase from Nocardia sp. CS682 was named as ThnA. The role of ThnA, in Nocardia sp. CS682 during the biosynthesis of 1,3,6,8 tetrahydroxynaphthalene (THN), which is the key intermediate of 1-(α-L-(2-O-methyl)-6-deoxymannopyranosyloxy)-3,6,8- trimethoxynaphthalene (IBR-3) was characterized. ThnA utilized five molecules of malonyl-CoA as a starter substrate to generate the polyketide 1,3,6,8-tetrahydroxynaphthalene, which could spontaneously be oxidized to the red flaviolin compound 2,5,7-trihydroxy-1,4-naphthoquinone. The amino acid sequence alignment of ThnA revealed similarities with a previously identified type III PKS and identified Cys<sup>138</sup>, Phe<sup>188</sup>, His<sup>270</sup>, and Asn<sup>303</sup> as four highly conserved active site amino acid residues, as found in other known polyketide synthases. In this study, we report the heterologous expression of the type III polyketide synthase thnA in S. lividans TK24 and the identification of THN production in a mutant strain. We also compared the transcription level of thnA in S. lividans TK24 and S. lividans pIBR25-thnA and found that thnA was only transcribed in the mutant.
객체지향 데이타베이스 시스템에서 인덱스 선택에 관한 연구
강푸르나(Kang Purna),유원경(Yoo Weon-Kyung) 한국정보과학회 1993 한국정보과학회 학술발표논문집 Vol.20 No.2
본 논문은 객체지향 데이타베이스에서 주어진 여러 개의 질의들을 가장 효율적으로 처리하기 위한 인덱스 구성 기법을 소개한 것이다. 각각의 질의는 가중치가 주어져 있고 질의에 대한 접근경로의 집합을 정의할 수 있다. 여기서 서로 중복되거나 겹쳐지는 접근경로를 고려하면서 가중치를 비용계산에 활용함으로써 주어진 질의에 대한 가장 효율적인 인덱스 구성을 결정지을 수 있다. 인덱스 구성에서 사용되는 인덱싱 방법은 이전에 연구 되어진 기법을 그대로 사용한다.
Biosynthesis of resveratrol glucosides compounds by amylosucarse DgAS
Samir Bahadur Thapa,Purna Bahadur Poudel,Jae Kyung Sohng 한국당과학회 2022 한국당과학회 학술대회 Vol.2022 No.07
A highly efficient biocatalytic system was constructed to make bioactive resveratrol poly-glucosides in a chain by using sucrose as a cheap source of UDP-glucose donors with the help of amylosucrase, DgAS from Deinococcus geothermalis. The system is superior as the reaction is very fast, direct, high rate of conversion of substrates to products, high thermostable, and regio-stereospecific with very effective in action at 40°C. Successfully our system can convert around 98% resveratrol to its resveratrol glucosides in a short time. The amylosucrase DgAS not only added glucose in multiple hydroxyl positions but also conjugates glucose in the chain as a result highly soluble glucosylated products are formed. Because of the highest thermostability and specific action among all known amylosucrases (ASases), DgAS has proven its importance for the transglucosylation activities in different polyphenols on an industrial scale. Therefore, our system can be used industrially for the cost-effective production of resveratrol glucosides.
Implementation of GPON as 5G Service Aggregation in IoT Use Case
Yohana Jayanti Aruan,Yoga Purna Tama,Dong-Seong Kim,Jae Min Lee 한국통신학회 2022 한국통신학회 학술대회논문집 Vol.2022 No.2
Driven by the increasing number of connected devices and parts, mobile technology is continuously and rapidly advancing towards the next generation of communication systems such as 5G and 6G. The 5G network needs to be constantly enhanced to better support the Internet of Things to satisfy the needs of connecting people, devices, and services. However, the current transport network, which needs to provide higher bandwidth and lower latencies, has not advanced simultaneously. Low latency is vital for IoT applications where milliseconds can eliminate disaster. Our analysis suggests that radically new communication technologies, network architectures, and deployment models will be needed to meet these demands. This paper proposed a gigabit passive optical network (GPON) as the main distributing technology for sharply rising data traffic and ultimate capacity optical access systems in the future Beyond-5G/6G era.