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      • KCI우수등재

        RESEARCH: Open Access : Validation of a simple binary scoring system for assessment of welfare measures of 10-day-old commercial broilers and their correlation with environmental parameters

        ( Priyanka Kumari ),( Hong Lim Choi ),( Shamira Hazi Metali ),( Siti Anisah Hazi Yussof ),( Jiwoon Han ) 한국동물자원과학회(구 한국축산학회) 2015 한국축산학회지 Vol.57 No.9

        Background: A simple binary scoring system (SBSS) was developed and used to assess the welfare measures of commercial broiler chickens in South Korea. We also correlated welfare measures with environmental parameters of broiler house. Our measures of welfare included lameness, hock burn (HB) and foot pad dermatitis (FPD), whilst environmental parameters included air temperature, relative humidity, air speed, light intensity, air quality (in particular carbon dioxide (CO2) and ammonia (NH3) concentrations) and airborne microbes. Results: The effect of environmental parameters on welfare measures was apparent even on 10-day-old broilers. A non-parametric correlation analysis revealed significant correlations between environmental parameters and welfare measures. The key environmental parameters were relative humidity and light intensity. The results indicate that there is a need for proper control of environmental conditions on poultry farms, which could reduce health problems and subsequently reduce disease and mortality. Conclusions: In conclusion, the simplicity of SBSS makes it preferable over more complex scoring systems and allows a farmer to more easily assess the welfare measures on their own farm.

      • KCI등재

        Real-Time Fluorescence Imaging in Thoracic Surgery

        Priyanka Das,Sheena Santos,G. Kate Park,이호석,최학수 대한흉부외과학회 2019 Journal of Chest Surgery (J Chest Surg) Vol.52 No.4

        Near-infrared (NIR) fluorescence imaging provides a safe and cost-efficient method for immediate data acquisition and visualization of tissues, with technical advantages including minimal autofluorescence, reduced photon absorption, and low scattering in tissue. In this review, we introduce recent advances in NIR fluorescence imaging systems for thoracic surgery that improve the identification of vital tissues and facilitate the resection of tumorous tissues. When coupled with appropriate NIR fluorophores, NIR fluorescence imaging may transform current intraoperative thoracic surgery methods by enhancing the precision of surgical procedures and augmenting postoperative outcomes through improvements in diagnostic accuracy and reductions in the remission rate.

      • KCI등재

        Primary pulmonary epithelioid inflammatory myofibroblastic sarcoma: a rare entity and a literature review

        Priyanka Singh,Aruna Nambirajan,Manish Kumar Gaur,Rahul Raj,Sunil Kumar,Prabhat Singh Malik,Deepali Jain 대한병리학회 2022 Journal of Pathology and Translational Medicine Vol.56 No.4

        Epithelioid inflammatory myofibroblastic sarcoma (EIMS) is an aggressive subtype of inflammatory myofibroblastic tumor (IMT) harboring anaplastic lymphoma kinase (<i>ALK</i>) gene fusions and is associated with high risk of local recurrence and poor prognosis. Herein, we present a young, non-smoking male who presented with complaints of cough and dyspnoea and was found to harbor a large right lower lobe lung mass. Biopsy showed a high-grade epithelioid to rhabdoid tumor with ALK and desmin protein expression. The patient initially received 5 cycles of crizotinib and remained stable for 1 year; however, he then developed multiple bony metastases, for which complete surgical resection was performed. Histopathology confirmed the diagnosis of EIMS, with <i>ALK</i> gene rearrangement demonstrated by fluorescence in situ hybridization. Postoperatively, the patient is asymptomatic with stable metastatic disease on crizotinib and has been started on palliative radiotherapy. EIMS is a very rare subtype of IMT that needs to be included in the differential diagnosis of ALKexpressing lung malignancies in young adults.

      • KCI등재
      • KCI등재

        Preparation of amorphous carvedilol polymeric microparticles for improvement of physicochemical properties

        Priyanka Bhosale,Yogesh Pore,Fahim Sayyad 한국약제학회 2012 Journal of Pharmaceutical Investigation Vol.42 No.6

        The aim of the present study was to enhance the physicochemical properties of poorly aqueous soluble carvedilol (CRV) by preparing its microparticles in presence and/or in absence of a hydrophilic carrier. The polymeric microparticles of CRV were prepared with polyvinylpyrrolidone K30 with or without addition of adsorbents like Aerosil200 and/or Sylysia350 by using spray drying technique. The dissolution profiles revealed that the drug and polymer ratio and colloidal silica both played critical role in solubility enhancement. The spray dried microparticles and drug alone were characterized by differential scanning calorimetry (DSC), X-ray powder diffraction, Fourier transformation infrared spectroscopy (FTIR), particle size analysis and scanning electron microscopy (SEM). DSC analysis showed that CRV transformed from the crystalline state to amorphous state by spray drying, confirmed by disappearance of its melting peak. The results of the X-ray analysis were in agreement with the thermal analysis data. It did not show characteristic crystalline drug peaks which confirmed that the amorphous form of CRV was present in the CRV loaded microparticles. FTIR analysis demonstrated hydrogen bonding interaction with an absence of significant chemical interaction between CRV and polymer. Spherical microparticles were yielded with smooth surfaces as observed by SEM. All in all, this work reveals that spray drying is a suitable technique for preparation of microparticles with improved physicochemical properties of CRV.

      • KCI등재

        In silico prediction of epitopes for Chikungunya viral strains

        Priyanka Kori,Shrishailnath S. Sajjan,Shivakumar B. Madagi 한국약제학회 2015 Journal of Pharmaceutical Investigation Vol.45 No.6

        Chikungunya is a viral infection transmitted by Aedes mosquitoes in humans. Currently there is no drug available for the treatment of this infection. In absence of a proven therapeutic, vaccines provide an alternative preventive measure for the spread of viral infection in risk prone population. The identification of epitopes is an important step in designing vaccines for viral infections. Traditional methods for vaccine production can be augmented by incorporation of in silico methods at epitopes identification stage. Protein sequences were retrieved for three different viral strains from primary database. Multiple sequence alignment for the retrieved sequences was performed by using MEGA 6.06 to spot the conserved regions. Various immunological databases were utilized to determine the binding affinity with T cells and B cells from structural and non-structural proteins from three different isolates of Chikungunya virus. Five different epitopes were predicted for both structural and non-structural proteins. The epitopes ‘‘KKKPGRRERMCMKIE’’ and ‘‘DAEKEAEEEREAELT’’ and ‘‘AEEEREAEL’’ were predicted as core sequences for class I and class II MHC molecules whereas ‘‘SSKYDLECAQ’’ and ‘‘QVLKAKNIGL’’ were predicted as probable B cell epitopes for structural and non-structural proteins respectively. The identified epitopes can be used for developing a broad spectrum vaccines having effectiveness against different strains of Chikungunya.

      • KCI등재

        Investigating the Characteristics and Responses of Diacetylene Based Materials as Spray-On Colorimetric Sensors

        Priyanka Shiveshwarkar,Savier Vega Siurano,Mahri Kadyrova,Natalie Tran,Justyn Jaworski 한국고분자학회 2022 Macromolecular Research Vol.30 No.1

        Polydiacetylene based sensors have been used for a variety of sensing applications. Here we demonstrate that diacetylene-containing amphiphiles could be spray processed to provide unique sensor coatings that may be applied to a variety of material surfaces. Utilizing an airbrushing technique, we examined processing parameters to yield spray-on sensors for detecting UV, temperature, as well as chemical/ solvent targets depending on the pendant side chain chemistry of the resulting polydiacetylene coating. We observed that the concentration, carrier solvent, and UV exposure time had a significant effect on the colorimetric response of the sprayed on coating with better responses observed at higher amphiphile concentration and shorter polymerization times. We expect this approach to generating spray-on responsive coatings will provide a widely deployable means for detection that may be customized for a variety of sensing applications.

      • KCI등재

        A simplified model for biomass pyrolysis in a fluidized bed reactor

        Priyanka Kaushal,Jalal Abedi 한국공업화학회 2010 Journal of Industrial and Engineering Chemistry Vol.16 No.5

        A reaction scheme of a set of three parallel reactions followed by a set of two parallel reactions has been used to describe the primary and secondary reactions of biomass pyrolysis in a fluidized bed reactor. A simple first-order kinetic approach has been applied to predict the product yields. The pyrolysis model detailed in this paper is actually a sub-model. The effects of operating parameters on biomass pyrolysis product yield were simulated. Results show that reaction temperature plays an important role in the yield of bio-oil. The model is robust and can predict good results in a gasification environment as well. Good agreement between predicted and published results was obtained. 2010 The Korean Society of Industrial and Engineering Chemistry. Published by Elsevier B.V. All rights reserved.

      • KCI등재

        Polymer Compositional Ratio-Dependent Morphology, Crystallinity, Dielectric Dispersion, Structural Dynamics, and Electrical Conductivity of PVDF/PEO Blend Films

        Priyanka Dhatarwal,Ram Jeewan Sengwa 한국고분자학회 2019 Macromolecular Research Vol.27 No.10

        The polymer blend (PB) films consisted of poly(vinylidene fluoride) (PVDF) and poly(ethylene oxide) (PEO) with different compositional ratios (i.e., PVDF/PEO =100/0, 75/25, 50/50, 25/75, and 0/100 wt%) have been prepared by solution casting method. These PB films were characterized by scanning electron microscopy (SEM), energy dispersive X-ray (EDX) spectroscopy, X-ray diffraction (XRD), Fourier transform infrared (FTIR) spectroscopy, and dielectric relaxation spectroscopy (DRS). The pristine films of PVDF and PEO have spherulite morphologies, which change enormously with the variation of their compositions in blend films. The EDX spectra confirm the linear variation of the amount of respective polymer elements, with the change of its compositional ratio in the PB films. The XRD and FTIR results confirm that the semicrystalline PVDF film has predominantly α- and β-phase crystals. The degree of crystallinity of these PB films exhibits non-linear increase, with increasing amount of PEO in the films. The relative fraction of the β-phase crystal of the PVDF in these complex PB films has been determined from the fractional relations based on the areas and intensities of crystalline peaks, observed in their XRD patterns which is found the maximum (~50%) for the 75 PVDF/25 PEO blend film. The dielectric dispersion of these PB films in the frequency window of 20 Hz-1MHz at 27 °C reveals that the real part of the complex permittivity is governed predominantly by the interfacial polarization effect at lower audio frequencies, whereas it mainly depends on the polymer compositional ratio at higher radio frequencies. The segmental relaxation process peak of the PEO chain observed in the loss part of the electric modulus spectra, shifts toward the lower frequency side with a significant suppression of intensity as the amount of PVDF enhances in the PB films. This result confirms that the PEO dynamics face considerable hindrance by the PVDF structures. The dc electrical conductivity of these PB films increases non-linearly with increasing amount of PEO in the films, and varies by more than an order of magnitude with the variation of the compositional ratio over the entire range. The temperature-dependent study of 50 PVDF/50 PEO blend film confirms its thermally activated dielectric properties and the structural dynamics with the relaxation activation energy of 0.23 eV. The compositional ratio-dependent dielectric properties of PVDF/PEO blend films offer a promising potential for their use as dielectric permittivity- and electrical conductivity-tunable insulating materials, with engineered functionality for flexible electronics and electrical devices.

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