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      • KCI등재

        Prevalence, Risk Factors, and Psychological Effects of Primary Nocturnal Enuresis in Chinese Young Adults

        Hui Jie Hu,Zhen Wei Zhang,Yu Liang,Yan Yan Luo,Qi Feng Dou,Cui Ping Song,Hui Min Zhang,Ying Zhao,Guang Run Tian,Ke Zhang,Qiu Fang Mao,Jing Gui Song,Soren Rittig,Jian Guo Wen 대한배뇨장애요실금학회 2021 International Neurourology Journal Vol.25 No.1

        Purpose: This study aimed to investigate the prevalence, risk factors, and effects of primary nocturnal enuresis (PNE) on physical and mental health in young adults in mainland China. Methods: An anonymous questionnaire was used to collect information including the sociodemographic characteristics, history of PNE, family history, daytime voiding symptoms, Pittsburgh Sleep Quality Index (PSQI) scores, Self-Esteem Scale (SES), and Self-Rating Depression Scale (SDS). A total of 22,500 university students from 23 provinces and 368 cities in mainland China were included. Results: In total, 21,082 questionnaires were collected, and 20,345 of them qualified for statistical analysis. The PNE prevalence was 1.17%, and the distribution of monosymptomatic nocturnal enuresis (MNE) and nonmonosymptomatic nocturnal enuresis (NMNE) was 66.1% and 33.9%, respectively. In total, 28% of respondents with PNE reported bedwetting daily, 31.6% between 1 and 7 times weekly, and 40.4% between 1 and 4 times monthly; 80% of PNE cases had no history of treatment. The prevalence of PNE in patients with a family history, frequency, urgency, urinary incontinence, and recurrent urinary tract infections was significantly higher than in those without these conditions (P<0.001). PNE was significantly correlated with the PSQI total score (sleep quality) (P=0.011). The SES score was lower and the SDS was higher (P<0.001) in the PNE group than in those without PNE. Conclusions: In mainland China, the PNE prevalence among young adults was found to be high, and PNE had significant effects on physical and mental health. Risk factors included a family history, daytime voiding symptoms, and lack of treatment.

      • KCI등재

        Simulation and Experiments on Cutting Forces and Cutting Temperature in High Speed Milling of 300M Steel under CMQL and Dry Conditions

        Hui-Ping Zhang,Qing-Yu Zhang,Yi Ren,Tony Shay,Guo-Liang Liu 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.8

        The effects of cryogenic minimum quantity lubrication (CMQL) on cutting forces and cutting temperature are analyzed in high speed milling of 300M steel. The influences of cutting parameters on cutting forces and cutting temperature are predicted by analogue simulation. Based on single-factor comparative test, the variation laws of cutting forces F and cutting temperature T with cutting parameters are studied in high speed milling of 300M steel under dry and CMQL conditions. Under the condition of CMQL, the influence of cutting parameters (cutting speed v, feed per tooth fz, cutting depth ap and cutting width ae) on cutting forces and the cutting temperature are analyzed by orthogonal test, and the prediction models of cutting forces and cutting temperature are established. The results show that CMQL condition can effectively reduce cutting forces and cutting temperature in the cutting process. Under the condition of CMQL, the cutting depth on the cutting forces is most significant, and the cutting speed has the greatest influence on the cutting temperature. The prediction model of cutting forces and cutting temperature is established, which can be a valuable reference for actual machining.

      • KCI등재

        Morphological defense of the egg mass of Spodoptera frugiperda (Lepidoptera: Noctuidae) affects parasitic capacity and alters behaviors of egg parasitoid wasps

        Dong Hui,Zhu Kai-hui,Zhao Qian,Bai Xue-ping,Zhou Jin-cheng,Zhang Li-sheng 한국응용곤충학회 2021 Journal of Asia-Pacific Entomology Vol.24 No.3

        The fall armyworm, Spodoptera frugiperda, is a dangerous pest of cereals originating from the tropical and sub tropical parts of the Americas. It has invaded over a hundred countries and is spreading rapidly throughout East Asia. Biological control programs are a “model strategy” for the control of invasive pests. Egg parasitoids Tele nomus remus and Trichogramma pretiosum are viewed as candidates for the control of S. frugiperda. The aim of this study was to evaluate the behavioral patterns and parasitism efficacy of Te. remus, Tr. pretiosum, and Tricho gramma dendrolimi on S. frugiperda egg masses with and without scales. The proportion of parasitism by Te. remus was significantly higher than that by Tr. dendrolimi and Tr. pretiosum. The proportion of parasitism by Tr. pre tiosum and Tr. dendrolimi on egg masses with scales was significantly lower than that on egg masses without scales. However, Te. remus had a similar proportion of parasitism on egg masses with and without scales. Residence time, oviposition time, oviposition frequency, risk of host being found, and risk of parasitism by Te. remus were significantly higher than the corresponding parameters of Tr. pretiosum and Tr. dendrolimi. Tr. pre tiosum females exhibited a higher residence time, oviposition time, oviposition frequency, risk of host being found, and risk of parasitism than those of Tr. dendrolimi females. In addition, Te. remus females often crept into the scale layer covering the egg masses, whereas Tr. dendrolimi and Tr. pretiosum females did not; they could only parasitize the eggs located on the periphery of the egg mass. Both Te. remus and Tr. pretiosum females had similar proportions of superparasitism, which were significantly higher than that of Tr. dendrolimi. Therefore, Te. remus is the dominant egg parasitoid of S. frugiperda and this has important implications for developing augmentative biological control strategies for S. frugiperda.

      • KCI등재

        The pivotal role of the NLRC4 inflammasome in neuroinflammation after intracerebral hemorrhage in rats

        Gan Hui,Zhang Li,Chen Hui,Xiao Han,Wang Lu,Zhai Xuan,Jiang Ning,Liang Ping,Zheng Shuyue,Zhao Jing 생화학분자생물학회 2021 Experimental and molecular medicine Vol.53 No.-

        The NLRC4 inflammasome, a member of the nucleotide-binding and oligomerization domain-like receptor (NLR) family, amplifies inflammation by facilitating the processing of caspase-1, interleukin (IL)–1β, and IL-18. We explored whether NLRC4 knockdown alleviated inflammatory injury following intracerebral hemorrhage (ICH). Furthermore, we investigated whether NLRC4 inflammasome activation can be adjusted by the regulator of G protein signaling 2/leucine-rich repeat kinase-2 pathway. Fifty microliters of arterial blood was drawn and injected into the basal ganglion to simulate the ICH model. NLRC4 small interfering RNAs (siRNAs) were utilized to knockdown NLRC4. An LRRK2 inhibitor (GNE7915) was injected into the abdominal cavity. Short hairpin (sh) RNA lentiviruses and lentiviruses containing RGS2 were designed and applied to knockdown and promote RGS2 expression. Neurological functions, brain edema, Western blot, enzyme-linked immunosorbent, hematoxylin and eosin staining, Nissl staining, immunoprecipitation, immunofluorescence assay and Evans blue dye extravasation and autofluorescence assay were evaluated. It was shown that the NLRC4 inflammasome was activated following ICH injury. NLRC4 knockdown extenuated neuronal death, damage to the blood-brain barrier, brain edema and neurological deficiency 3 days after ICH. NLRC4 knockdown reduced myeloperoxidase (MPO) cells as well as tumor necrosis factor (TNF)-α, interleukin (IL)-6, IL-1β and IL-18 following ICH. GNE7915 reduced pNLRC4 and NLRC4 inflammasome activation. RGS2 suppressed the interaction of LRRK2 and NLRC4 and NLRC4 inflammasome activation by regulating pLRRK2. Our study demonstrated that the NLRC4 inflammasome may aggravate the inflammatory injury induced by ICH and that RGS2/LRRK2 may relieve inflammatory injury by restraining NLRC4 inflammasome activation.

      • KCI등재

        인터랙티브가 적용된 스포츠 의류 전문점에 대한 연구

        장회평(Hui Ping Zhang),강재철(Jae Cheol Kang) 한국디자인리서치학회 2023 한국디자인리서치 Vol.8 No.2

        과학과 기술의 지속적인 발전과 응용에 따라 설치미술(Installation Art)은 새로운 기술과 뉴미디어를 융합하여 새로운 표현의 형식을 보여주고 있으며, 인터랙티브 장치(Interactive Installation)는 전통적인 설치미술과 현대 기술의 결합으로 점차 실내 공간에 적용되고 있다. 본 논문은 의류전문점 공간에 인터랙티브 장치의 적용에 대해 연구하였으며, 구체적으로 인터랙티브 장치의 특성(상호작용성, 체험성, 과학 기술성, 오락성)이 소비자의 감정 체험 및 지각된 유용성에 미치는 영향, 또한 인터랙티브 장치가 적용한 의류전문점 공간이 소비자의 구매 의사에 미치는 영향에 대해 분석 및 연구하였다. 본 연구는 20~60세 의류전문점을 자주 이용한 소비자를 연구 대상으로 삼아 SPSS 25.0 프로그램을 활용하여 수집된 252개의 유효 설문지 데이터를 분석하였다. 분석한 결과에 따라 의류전문점 공간의 인터랙티브 장치의 특성인 상호작용성, 체험성, 과학 기술성, 오락성이 소비자의 감정 체험과 지각된 유용성에 유의한 정(+)의 영향을 미치는 동시에 감정 체험과 지각된 유용성이 구매 의사에 유의한 정(+)의 영향을 미치는 것으로 나타났다. 이 연구는 의류 판매장 공간의 형태를 다양화할 수 있으면서 소비자를 유치하여 소비 가능성을 높일 수 있다. 또한 의류 판매장 공간에 인터랙티브 장치를 합리적으로 적용할 수 있도록 이론적 참고 자료를 제공할 수 있다. With the development and application of science and technology, Installation Art integrates new technology and media, and Interactive Installation, as a combination of traditional installation art and modern technology, is gradually applied in indoor space. The purpose of this thesis is to study the application of interactive devices in clothing store space, to analyze the effects of interactive devices on consumers' emotional experience and perceived usefulness. The results show that the interactive, experiential, technological and entertainment of the interactive devices in the clothing store space have positive effects on the emotional experience and perceived usefulness. This research can enrich the space form of clothing store and attract consumers to increase the possibility of consumer consumption, and provide some theoretical reference for the rational use of interactive devices in clothing store space.

      • Long Non-coding RNA GAS5 Functions as a Tumor Suppressor in Renal Cell Carcinoma

        Qiao, Hui-Ping,Gao, Wei-Shi,Huo, Jian-Xin,Yang, Zhan-Shan Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2

        Background: Renal cell carcinoma (RCC) is a malignancy with a poor prognosis. We aimed to explore whether the expression of Long Non-Coding RNA (LncRNA) growth arrest-specific transcript 5 (GAS5) is associated with RCC genesis. Methods: We selected twelve clinical samples diagnosed for renal clear cell carcinoma and found that the LncRNA GAS5 transcript levels were significantly reduced relative to those in adjacent unaffected normal renal tissues. Results: In addition, expression of GAS5 was lower in the RCC cell line A498 than that in normal renal cell line HK-2. Furthermore, using functional expression cloning, we found that overexpression of GAS5 in A498 cells inhibited cell proliferation, induced cell apoptosis and arrested cell cycling. At the same time, the migration and invasion potential of A498 cells were inhibited compared to control groups. Conclusion: Our study provided the first evidence that a decrease in GAS5 expression is associated with RCC genesis and progression and overexpression of GAS5 can act as a tumor suppressor for RCC, providing a potential attractive therapeutic approach for this malignancy.

      • KCI등재

        스포츠 브랜드 플래그십 스토어의 공간체험 디자인 특성에 관한 연구

        장회평(Hui Ping Zhang),강재철(Jae Cheol Kang) 한국디자인리서치학회 2023 한국디자인리서치 Vol.8 No.3

        플래그십 스토어의 공간 디자인은 방문 소비자의 브랜드 이미지에 영향을 미치고, 이는 다시 소비자의 구매의도에 영향을 미친다. 따라서 본 연구에서는 소비자의 관심을 끌기 위해 경험 디자인을 이론적 근거로 삼아 스포츠 브랜드의 플래그십 스토어 공간 디자인의 특성인 비일상성, 상호작용성, 역동성 및 연상성이 브랜드 이미지와 구매의도에 미치는 영향을 연구하는 것을 목적으로 한다. 본 연구의 목적을 달성하기 위해 NIKE와 ADIDAS의 두 스포츠 브랜드플래그십 스토어 공간을 조사사례로 선정하여 스포츠 브랜드 플래그십 스토어를 방문한 소비자를 대상으로 설문조사를 실시하였으며 최종적으로 302개의 유효한 설문지를 회수하였다. 설문지에서 수집된 데이터를SPSS26.0 및 AMOS24.0 통계 프로그램을 사용하여 빈도 분석, 신뢰성 분석, 검증 요인 분석, 상관 관계 분석 및 회귀 분석을 수행한 결과 스포츠 브랜드 플래그십 스토어 공간 경험디자인의 특성인 비일상성, 상호작용성, 역동성, 연상성이 브랜드 이미지에 유의한 정(+)의 영향을 미치는 것으로 나타났다. 마찬가지로 브랜드 이미지는 구매 의도에 정(+)의 영향을 미치는 것으로 나타났다. 이에 따라 본 연구는 스포츠 브랜드 플래그십 스토어의 공간 기획에 대한 실증 데이터 및 이론적 지원을 제공할 수 있는 것에 그 의의가 있다. Flagship shop space design influences the brand image of visiting consumers, which in turn affects purchase intention. Therefore, in order to attract consumers, this study takes experience design as the theoretical basis and aims to investigate the influence of experience design characteristics (non-daily, interactive, dynamic and associative) on brand image and purchase intention in the design of sports brand flagship shop space. In order to meet the purpose of this study, two sports brand flagship shop spaces, NIKE and ADIDAS, were selected as investigation cases, and a questionnaire survey was carried out with the group of consumers visiting the sports brand flagship shops, and 302 valid questionnaires were finally returned, and the collected data were analysed by frequency analysis, reliability analysis, validation factor analysis, correlation analysis, and regression analysis using the statistical programs of SPSS26.0 and AMOS 24.0. analysis and regression analysis. The results of the study are as follows: (1) The spatial experience design characteristics of flagship shops of sports brands (non-routine, interactivity, dynamism and associativity) have a positive impact on brand image. (2) Brand image has a positive effect on consumers' purchase intention. The results of this study can provide empirical data and theoretical support for the spatial planning of sports brand flagship shops.

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