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      • KCI등재

        A Cash Management Model with Capital Gains Taxation-Two Assets Certainty Model

        Phang, Sukhyun 한국경영과학회 1979 韓國經營科學會誌 Vol.4 No.1

        The cash management problem as a part of working capital management has been extensively studied. By and large the articles surveyed lacked consideration of long-term assets and the proper tax treatment of them. Recognizing that investment activities - long-term as well as short-term generate cash inflows, leads one to conclude that these investments should be included in the cash management problem. The liquidity of long term investments is an integral part of the cash management problem. This paper for-mulated a cash management models which incorporate the effect of long term investments and their liquidity on cash holdings. Although all of the models formulated could be solved using mathematical programming techniques, the mere size of the problem in terms of the number of variables and constraints leads one to seek other methods. For this reason rules were developed using the Kuhn-Tucker conditions thereby substantially avoiding the programming calculations or at least easing them significantly.

      • KCI등재후보

        PVA/PVP Nanofibres Incorporated with Ecklonia cava Phlorotannins Exhibit Excellent Cytocompatibility and Accelerate Hyperglycaemic Wound Healing

        Phang Shou Jin,Teh Huey Xhin,Looi Mee Lee,Fauzi Mh Busra,Neo Yun Ping,Arumugam Bavani,Kuppusamy Umah Rani 한국조직공학과 재생의학회 2024 조직공학과 재생의학 Vol.21 No.2

        Background: Diabetic foot ulcer (DFU) is a major debilitating complication of diabetes. The lack of effective diabetic wound dressings has been a significant problem in DFU management. In this study, we aim to establish a phlorotannin-incorporated nanofibre system and determine its potential in accelerating hyperglycaemic wound healing. Methods: The effective dose of Ecklonia cava phlorotannins (ECP) for hyperglycaemic wound healing was determined prior to phlorotannin nanofibre fabrication using polyvinyl-alcohol (PVA), polyvinylpyrrolidone (PVP), and ECP. Vapour glutaraldehyde was used for crosslinking of the PVA/PVP nanofibres. The phlorotannin nanofibres were characterised, and their safety and cytocompatibility were validated. Next, the wound healing effect of phlorotannin nanofibres was determined with 2D wound scratch assay, whereas immunofluorescence staining of Collagen-I (Col-I) and Cytokeratin-14 (CK-14) was performed in human dermal fibroblasts (HDF) and human epidermal keratinocytes (HEK), respectively. Results: Our results demonstrated that 0.01 μg/mL ECP significantly improved hyperglycaemic wound healing without compromising cell viability and proliferation. Among all nanofibres, PVA/PVP/0.01 wt% ECP nanofibres exhibited the best hyperglycaemic wound healing effect. They displayed a diameter of 334.7 ± 10.1 nm, a porosity of 40.7 ± 3.3%, and a WVTR of 1718.1 ± 32.3 g/m2/day. Besides, the FTIR spectra and phlorotannin release profile validated the successful vapour glutaraldehyde crosslinking and ECP incorporation. We also demonstrated the potential of phlorotannin nanofibres as a non-cytotoxic wound dressing as they support the viability and proliferation of both HDF and HEK. Furthermore, phlorotannin nanofibres significantly ameliorated the impaired hyperglycaemic wound healing and restored the hyperglycaemic-induced Col-I reduction in HDF. Conclusion: Taken together, our findings show that phlorotannin nanofibres have the potential to be used as a diabetic wound dressing. Background: Diabetic foot ulcer (DFU) is a major debilitating complication of diabetes. The lack of effective diabetic wound dressings has been a significant problem in DFU management. In this study, we aim to establish a phlorotannin-incorporated nanofibre system and determine its potential in accelerating hyperglycaemic wound healing. Methods: The effective dose of Ecklonia cava phlorotannins (ECP) for hyperglycaemic wound healing was determined prior to phlorotannin nanofibre fabrication using polyvinyl-alcohol (PVA), polyvinylpyrrolidone (PVP), and ECP. Vapour glutaraldehyde was used for crosslinking of the PVA/PVP nanofibres. The phlorotannin nanofibres were characterised, and their safety and cytocompatibility were validated. Next, the wound healing effect of phlorotannin nanofibres was determined with 2D wound scratch assay, whereas immunofluorescence staining of Collagen-I (Col-I) and Cytokeratin-14 (CK-14) was performed in human dermal fibroblasts (HDF) and human epidermal keratinocytes (HEK), respectively. Results: Our results demonstrated that 0.01 μg/mL ECP significantly improved hyperglycaemic wound healing without compromising cell viability and proliferation. Among all nanofibres, PVA/PVP/0.01 wt% ECP nanofibres exhibited the best hyperglycaemic wound healing effect. They displayed a diameter of 334.7 ± 10.1 nm, a porosity of 40.7 ± 3.3%, and a WVTR of 1718.1 ± 32.3 g/m2/day. Besides, the FTIR spectra and phlorotannin release profile validated the successful vapour glutaraldehyde crosslinking and ECP incorporation. We also demonstrated the potential of phlorotannin nanofibres as a non-cytotoxic wound dressing as they support the viability and proliferation of both HDF and HEK. Furthermore, phlorotannin nanofibres significantly ameliorated the impaired hyperglycaemic wound healing and restored the hyperglycaemic-induced Col-I reduction in HDF. Conclusion: Taken together, our findings show that phlorotannin nanofibres have the potential to be used as a diabetic wound dressing.

      • Selective CO<sub>2</sub> adsorption and proton conductivity in the two-dimensional Zn(<small>II</small>) framework with protruded water molecules and flexible ether linkers

        Phang, Won Ju,Lee, Woo Ram,Yoo, Kicheon,Kim, BongSoo,Hong, Chang Seop The Royal Society of Chemistry 2013 Dalton transactions Vol.42 No.22

        <P>A two-dimensional (2D) Zn(<SMALL>II</SMALL>) metal–organic framework with flexible aryl ether linkers and water molecules exposed to the pores was prepared. The supramolecular three-dimensional (3D) network is generated by the presence of extensive π–π contacts, which could be responsible for gas uptake. The water molecules and oxygen atoms from the flexible linkers create a polar environment within the integrated framework, leading to simultaneous selective CO<SUB>2</SUB> adsorption and proton conductivity in the two-dimensional Zn(<SMALL>II</SMALL>) framework.</P> <P>Graphic Abstract</P><P>A two-dimensional Zn(<SMALL>II</SMALL>) metal–organic framework with flexible aryl ether linkers and water molecules exposed to the pores exhibits simultaneous selective CO<SUB>2</SUB> adsorption and proton conductivity. <IMG SRC='http://pubs.rsc.org/services/images/RSCpubs.ePlatform.Service.FreeContent.ImageService.svc/ImageService/image/GA?id=c3dt50896j'> </P>

      • pH‐Dependent Proton Conducting Behavior in a Metal–Organic Framework Material

        Phang, Won Ju,Lee, Woo Ram,Yoo, Kicheon,Ryu, Dae Won,Kim, BongSoo,Hong, Chang Seop WILEY‐VCH Verlag 2014 Angewandte Chemie Vol.126 No.32

        <P><B>Abstract</B></P><P>A porous metal–organic framework (MOF), [Ni<SUB>2</SUB>(dobdc)(H<SUB>2</SUB>O)<SUB>2</SUB>]⋅6 H<SUB>2</SUB>O (Ni<SUB>2</SUB>(dobdc) or Ni‐MOF‐74; dobdc<SUP>4−</SUP>=2,5‐dioxido‐1,4‐benzenedicarboxylate) with hexagonal channels was synthesized using a microwave‐assisted solvothermal reaction. Soaking Ni<SUB>2</SUB>(dobdc) in sulfuric acid solutions at different pH values afforded new proton‐conducting frameworks, H<SUP>+</SUP>@Ni<SUB>2</SUB>(dobdc). At pH 1.8, the acidified MOF shows proton conductivity of 2.2×10<SUP>−2</SUP> S cm<SUP>−1</SUP> at 80 °C and 95 % relative humidity (RH), approaching the highest values reported for MOFs. Proton conduction occurs via the Grotthuss mechanism with a significantly low activation energy as compared to other proton‐conducting MOFs. Protonated water clusters within the pores of H<SUP>+</SUP>@Ni<SUB>2</SUB>(dobdc) play an important role in the conduction process.</P>

      • SCOPUSKCI등재

        Structures and Sorption Properties of 2-Methylbenzimidazolate-Based Zn(II) Frameworks

        Phang, Won Ju,Lee, Woo Ram,Hong, Chang Seop Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.8

        The syntheses and crystal structures of a three-dimensional (3D) coordination network $[Zn_4(2-mBIM)_5-(C_2H_6NCOO)(HCOO)({\mu}-OH)]{\cdot}DMF$ ($1{\cdot}$DMF; 2-mBIM = 2-methylbenzimidazolate) and a two-dimensional (2D) layer $[Zn_2(2-mBIM)_3(HCOO)(H_2O)]{\cdot}DMF$ ($2{\cdot}DMF$) are reported. Different structures were produced depending on the ratio of reactants. Structurally, 1 illustrates the formation of a unique framework based on a 2-mBIM bridge with the side group on an imidazole ring, while 2 possesses a honeycomb layer built up purely from imidazolates. For gas sorption, $CO_2$ is adsorbed on the activated phase of 1 but $N_2$ is not taken up.

      • A Mixed-Method Study on the Motivational Effects of Web 2.0 Technology on Mother Tongue Language (Chinese Language) Learning

        ( Phang Yuh Koon ) 한국교육공학회 2014 한국교육공학회 학술대회발표자료집 Vol.2014 No.2

        Motivated students are every teacher``s dream and they are diligent, goals-directed, focused and determined to attain success in their learning. As scholars have stated, motivation is the key to academic success as well as fostering lifelong learning. However, we all know that the motivation that drives students`` learning stems from various sources, internal to the learner, external, or both. The purpose of this study is to examine the motivational influence of Web 2.0 technology on a class sample of n=40 Secondary One elementary students`` learning of their Mother Tongue Language (Chinese Language). Examining the motivation aspect is essential for language teachers because motivation is one of the key drivers of language learning success Now, the fundamental question is on how do we motivate the students in learning their Mother Tongue Language (Chinese Language)? Significantly, researchers have evidenced that Chinese language teachers are challenged with the predicament of engaging and motivating students to learn the Chinese Language and at the same time the worrying concern of students`` declining Chinese Language proficiency level has also surface. Correspondingly, some students perceive their mother tongue merely as an examination subject for progress in the academic ladder, while others have little or no incentive to learn it in schools. Researchers and scholars have also highlighted that theories of motivation generally seek to explicate why and how individuals choose, perform, and persevere in various activities; but ultimately, these theories also enlightened those whom endeavor to motivate others. But for the classroom teachers, they are more interested in finding out what they can do to stimulate students`` motivation to learn than investigating what accounts for amounts of variance in language proficiency, which serves as a typical preoccupation in research. Classroom practitioners are enthusiastic to discover ways of increasing the quantity and quality of students`` engagement and motivation in learning activities, in view of the fact that students`` active classroom participation engages learning. As a matter of fact, numerous research findings have demonstrated that the greater the motivation to use the language, the higher the success rate the learners can attained in language learning. Hence, it is paramount to foster students`` motivation in using and learning the language, and this need to be done in an extrinsicallymotivated learning environment which gradually enhances the intrinsic motivation of the individual learner. More recently, research about the use of Web 2.0 tools in the language classroom has revealed that students anticipate and welcome the use of technology in language instruction and learning and the employment of Web 2.0 technology has been associated to greater motivation and technological tools like blogs and Wikis have been observed to engage and improve students`` writing. Nonetheless, some assert that students perceive the Web 2.0 technologies as having a positive relationship with them and teachers`` diving into the media that the learners have already know and love is a plausible way to motivate, excite, and connect to the students. Hence, is it necessary so that Web 2.0 technology motivates students in the learning of a language, particularly in the context of their Mother Tongue Language (Chinese Language)? Specifically, this mixedmethod study is guided by two principal research questions namely: Does the use of Web 2.0 technology affect Singapore students`` motivation for the Chinese Language learning? How does the use of Web 2.0 technology influence the students`` motivation for Chinese Language learning? In the present study, the Chinese Language Motivation Scale (CLMOTS) developed by Soh (1993), a self-perception survey questionnaire, together with students`` semi-structured interviews are employed to acquire a more-in depth understanding and a comprehensive picture of the significance and influence of technology on students`` motivation for Chinese Language learning. More importantly, the quantitative and qualitative findings and results would provide insights to language educators and classroom practitioners on how to better harness the affordances of Web 2.0 technology while simultaneously rethink and redesign their instructional practice, strategies and ICT-enabled pedagogies to motivate and transform Mother Tongue Languages (Chinese Language) or second Languages learning.

      • KCI우수등재
      • KCI등재

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