An optical digital logic unit using magneto-optic spatial light modulators

Pearson, Brian Thomas UMI 1992 국내박사

The pneumatikos-psychikos terminology in 1 Corinthians : a study in the theology of the Corinthian opponents of Paul and its relation to gnosticism

Pearson, Birger Albert Published by Society of Biblical Literature for th 1973 국내박사

GENDER, IMAGE, AND IDEALS AT THE CISTERCIAN CONVENT OF FLINES, 1500-1575(BELGIUM)

PEARSON, ANDREA GAIL University of California 1995 해외박사

INTEGRATIONS OF ART AND ARCHITECTURE IN THE WORK OF LE CORBUSIER : THEORY AND PRACTICE FROM ORNAMENTALISM TO THE "SYNTHESIS OF THE MAJOR ARTS" (SWITZERLAND)

PEARSON, CHRISTOPHER ERIC MORGAN Stanford University 1995 해외박사

Sex in the field : Photography at the Kinsey Institute

Yamashiro, Jennifer Pearson Indiana University 2002 해외박사

Inteins as Biomolecular Switches: Applications in Drug Discovery, Protein Purification, and Stress Response

Pearson, C. Seth ProQuest Dissertations & Theses Rensselaer Polytec 2018 해외박사(DDOD)

Inteins are protein elements that autocatalytically excise themselves from a host protein in a process called protein splicing. The two flanking sequences of the host protein, called the N- and C-exteins, are subsequently ligated with a native p. During this process, the intein breaks two peptide bonds and forms a third. Taking advantage of the intein's ability to catalyze these reactions, both within the natural host as well as in vitro for biotechnological applications, provides an att. Our work focuses on two of the three inteins found in the human pathogen Mycobacterium tuberculosis (Mtu), RecA and SufB. The intein-interrupted proteins are important for the viability of Mtu. Preventing intein excision, and thus the formation. Turning to methods of control for in vitro applications, we introduced a mutation in Mtu RecA that causes the intein to spontaneously form a thiazoline ring at the N-terminal splicing junction. While present, the thiazoline ring prevents any fur. The final aspect of our work is based on the intriguing hypothesis that inteins are not simply parasitic elements, but offer a beneficial protein-level control of host protein function. We demonstrated that Mtu SufB activity is inhibited in vivo. Overall, this work investigates strategies for controlling inteins in the realms of drug development, protein purification, and host regulation and stress response.

Determinants of Sedentary Behavior in College Freshman Students Using the Interaction Model of Client Health Behavior

Pearson Morales, Marilyn Ann University of Virginia 2011 해외박사(DDOD)

Overweight and obesity in the United States has increased for all ages. Health patterns established during adolescence are important for the development of adult health practices. Identified patterns of decreasing physical activity (PA) and increasing sedentary behavior (SB) develop as adolescent's transition to adulthood. The objectives of this theory based study are to identify the determinants of SB in college freshman using the Interaction Model of Client Health Behavior (IMCHB) elements of Client Singularity. What is the total variance of SB explained by the Client Singularity background and dynamic variables, and what percent of SB variance is explained by weight status and the belief of SB as a risk factor to future health status? The sample included a cross-sectional sample of freshman using a one time web-based survey. The dependent variable was SB measured in minutes categorized as high or low using a 4-item scale; and a continuous measure of SB as minutes using a 13-item scale. IVs were organized using IMCHB Client Singularity elements. Additional relationships are explored for active behavior. The LR analysis of the sample (N=537) found that 43% participate in high levels of SB. Findings showed that unhealthy BMI status, and Cons of Change significantly influenced engaging in high SB. The MR analysis of sample (N=537) found the mean SB was 869 minutes or 14.48 hours. Female gender, race, sedentary friends, unhealthy BMI status, and Cons of Change significantly influenced SB, and explained 13% of the variance. Perceived risk did not influence SB. More days spent in PA was related to less SB. IMCHB may assist in identifying the determinants of SB. The study provides information on the modifiable determinants of SB for use in intervention development to reduce or prevent overweight and obesity.

Stellar Streams, Dwarf Galaxy Pairs, and the Halos in Which They Reside

Pearson, Sarah Columbia University ProQuest Dissertations & These 2018 해외박사(DDOD)

In this Dissertation we explore how the nature of tidal interactions tear gravitationally bound systems apart into distinct morphological and kinematic structures. We use the properties of these structures, persisting for billions of years, to i. In particular, we use the properties of the thin, curved stellar stream emerging from the old, Milky Way globular cluster, Palomar 5 (Pal 5) to show that its mere existence can rule out a moderately triaxial potential model of our Galaxy. Pal 5. We carry out a systematic study of resolved neutral hydrogen (HI) synthesis maps of 10 interacting dwarf galaxy pairs. The pairs are located in a range of environments and captured at various interaction stages. We find that the neutral gas is e. We model a specific dwarf pair in our sample, NGC 4490/85, which is an isolated analog of the Magellanic Clouds and is surrounded by a &sim.

The response of molecular gases and modulated plasmas to short intense laser pulses

Pearson, Andrew James University of Maryland, College Park 2011 해외박사(DDOD)

In this thesis we study the response of two systems to short, intense laser pulses. The first system is a gas of diatomic molecules whose ensemble-averaged alignment features rotational revivals. We analyze the effect of a background plasma on the revival peaks. Both the revivals and the plasma are the result of a laser pulse passing through the gas. The second system is a density-modulated plasma channel. We study the generation of electromagnetic radiation by a laser pulse passing through this structure. The molecules in the gas are modeled as rigid rotors that interact first with the cycle-averaged electric field of the laser pulse, and second with the fluctuating electric field of the background plasma. The laser pulse generates a broad super-position of angular momentum eigenstates, resulting in the transient alignment of the molecules. Because of the time evolution properties of the angular momentum states, the alignment re-occurs periodically in field-free conditions. The alignment is calculated using a density matrix, and the background plasma is modeled using dressed particles. The result is decoherence between the phases of the basis states of the wavefunction, which causes decay of subsequent alignment peaks. We find that field-induced decoherence is competitive with collisional decoherence for small ionization fractions. The corrugated plasma channel is modeled using linear plasma theory, and the laser pulse is non-evolving. Corrugated channels support EM modes that have a Floquet dispersion relation, and thus consist of many spatial harmonics with subluminal phase velocities. This allows phase matching between the pulse and the EM modes. Since the pulse bandwidth includes THz frequencies, significant THz generation is possible. Here we consider realistic density profiles to obtain predictions of the THz power output and mode structure. We then estimate pulse depletion effects. The fraction of laser energy converted to THz is independent of laser pulse energy in the linear regime, and we find it to be around one percent. Extrapolating to a pulse energy of 0.5 J gives a THz power output of 6 mJ, with a pulse depletion length of less than 20 cm.

Evaluation of dosimetric properties of 6 MV & 10 MV photon beams from a linear accelerator with no flattening filter

Pearson, David The University of Toledo 2008 해외공개박사

A linear accelerator manufactured by Elekta, equipped with a multi leaf collimation (MLC) system has been modelled using Monte Carlo simulations with the photon flattening filter removed. The purpose of this investigation was to show that more efficient and more accurate Intensity Modulated Radiation Therapy (IMRT) treatments can be delivered from a standard linear accelerator with the flattening filter removed from the beam. A range of simulations of 6 MV and 10 MV photon were studied and compared to a model of a standard accelerator which included the flattening filter for those beams. Measurements using a scanning water phantom were also performed after the flattening filter had been removed. We show here that with the flattening filter removed, an increase to the dose on the central axis by a factor of 2.35 and 4.18 is achieved for 6 MV and 10 MV photon beams respectively using a standard 10x 10cm2 field size. A comparison of the dose at points at the field edges led to the result that, removal of the flattening filter reduced the dose at these points by approximately 10% for the 6 MV beam over the clinical range of field sizes. A further consequence of removing the flattening filter was the softening of the photon energy spectrum leading to a steeper reduction in dose at depths greater than dmax. Also studied was the electron contamination brought about by the removal of the filter. To reduce this electron contamination and thus reduce the skin dose to the patient we consider the use of an electron scattering foil in the beam path. The electron scattering foil had very little effect on dmax. From simulations of a standard 6MV beam, a filter-free beam and a filter-free beam with electron scattering foil, we deduce that the proportion of electrons in the photon beam is 0.35%, 0.28% and 0.27%, consecutively. In short, higher dose rates will result in decreased treatment times and the reduced dose outside of the field is indicative of reducing the dose to the surrounding tissue. Electron contamination was found to be comparable with conventional IMRT treatments carried out with a flattening filter.