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TEROS12 토양 센서를 이용한 간척농지 포화침출액 EC 계측 방법
백누리 ( Nuri Baek ),박서우 ( Seo-woo Park ),허수빈 ( Su-bin Heo ),신은서 ( Eun-seo Sin ),신은서(2) ( Eun-seo Sin(2) ),이지유 ( Ji-yu Lee ),신미르 ( Mi-reu Sin ),박승영 ( Seung-young Park ),안도영 ( Do-young An ),박현진 ( Hyun-jin 한국농공학회 2022 한국농공학회 학술대회초록집 Vol.2022 No.-
간척농지 염농도 관리를 위해서 염농도 자동계측기 설치가 확대되고 있다. 자동계측기에서는 용적전기전도도(Bulk electrical conductivity, EC<sub>b</sub>)가 측정되는데, EC<sub>b</sub>는 토양 수분에 크게 영향을 받는다. 따라서, EC<sub>b</sub>를 토양 수분함량에 독립적인 포화침출액 전기전도도(Saturated-paste extract EC, EC<sub>e</sub>)로 환산할 필요가 있다. 본 연구에서는, 실내 토조실험을 통해 사양토, 미사질양토, 미사질식토를 이용하여 EC<sub>b</sub>와 EC<sub>e</sub>의 상관관계를 구명하였다. 토조에 세 가지 수준의 염농도로 조정된 토양을 충진하고 염농도 센서(Teros12)를 설치한 후 수분을 과포화 상태로 조정하여 각각의 토양에 대해 약 2주간 실험을 수행하였다. 사양토의 EC<sub>e</sub>는 4.5, 7.0, 10.5 dS m<sup>-1</sup>, 미사질양토의 EC<sub>e</sub>는 4.3, 7.8, 11.4 dS m<sup>-1</sup>, 미사질식토의 EC<sub>e</sub>는 4.1, 6.7, 11.9 dS m<sup>-1</sup>였다. 시간이 경과함에 따라 토양 수분 함량은 증발에 의해 약 0.2 cm<sup>3</sup> cm<sup>-3</sup>로 감소하였다. 수분함량이 과포화에서 약 0.3 cm<sup>3</sup> cm<sup>-3</sup> 수준으로 감소하는 동안 EC<sub>b</sub>는 염 농축에 의해 증가하였지만, 그 이후부터는 수분함량이 감소함에 따라 이온 활동도가 감소하여 EC<sub>b</sub>도 감소하였다. 토성과 염농도 수준에 상관없이 EC<sub>e</sub>와 EC<sub>b</sub>의 비(EC<sub>e</sub>/EC<sub>b</sub>)는 수분함량과 2차 함수관계를 보였다. 이와 같은 상관관계 회귀식을 현장 계측기에 적용한 결과, 계측기에서 측정되는 용적수분함량과 EC<sub>b</sub>를 매개변수로 활용하여 EC<sub>e</sub>를 계측할 수 있었다. 따라서, 향후 염농도 자동계측기를 활용하면 토양 EC<sub>e</sub>의 장기 변동을 모니터링할 수 있으며, 이와 같은 시간에 따른 EC<sub>e</sub> 변화양상을 활용하여 목표 EC<sub>e</sub> 수준까지 제염되는 기간을 예측할 수 있을 것으로 기대된다.
TEROS12 토양 센서를 이용한 간척농지 포화침출액 EC 계측 방법
백누리 ( Nuri Baek ),박서우 ( Seo-woo Park ),허수빈 ( Su-bin Heo ),신은서 ( Eun-seo Sin ),신은서(2) ( Eun-seo Sin(2) ),이지유 ( Ji-yu Lee ),신미르 ( Mi-reu Sin ),박승영 ( Seung-young Park ),안도영 ( Do-young An ),박현진 ( Hyun-jin 한국농공학회 2022 한국농공학회 학술대회초록집 Vol.2022 No.-
간척농지 염농도 관리를 위해서 염농도 자동계측기 설치가 확대되고 있다. 자동계측기에서는 용적전기전도도(Bulk electrical conductivity, EC<sub>b</sub>)가 측정되는데, EC<sub>b</sub>는 토양 수분에 크게 영향을 받는다. 따라서, EC<sub>b</sub>를 토양 수분함량에 독립적인 포화침출액 전기전도도(Saturated-paste extract EC, EC<sub>e</sub>)로 환산할 필요가 있다. 본 연구에서는, 실내 토조실험을 통해 사양토, 미사질양토, 미사질식토를 이용하여 EC<sub>b</sub>와 EC<sub>e</sub>의 상관관계를 구명하였다. 토조에 세 가지 수준의 염농도로 조정된 토양을 충진하고 염농도 센서(Teros12)를 설치한 후 수분을 과포화 상태로 조정하여 각각의 토양에 대해 약 2주간 실험을 수행하였다. 사양토의 EC<sub>e</sub>는 4.5, 7.0, 10.5 dS m<sup>-1</sup>, 미사질양토의 EC<sub>e</sub>는 4.3, 7.8, 11.4 dS m<sup>-1</sup>, 미사질식토의 EC<sub>e</sub>는 4.1, 6.7, 11.9 dS m<sup>-1</sup>였다. 시간이 경과함에 따라 토양 수분 함량은 증발에 의해 약 0.2 cm<sup>3</sup> cm<sup>-3</sup>로 감소하였다. 수분함량이 과포화에서 약 0.3 cm<sup>3</sup> cm<sup>-3</sup> 수준으로 감소하는 동안 EC<sub>b</sub>는 염 농축에 의해 증가하였지만, 그 이후부터는 수분함량이 감소함에 따라 이온 활동도가 감소하여 EC<sub>b</sub>도 감소하였다. 토성과 염농도 수준에 상관없이 EC<sub>e</sub>와 EC<sub>b</sub>의 비(EC<sub>e</sub>/EC<sub>b</sub>)는 수분함량과 2차 함수관계를 보였다. 이와 같은 상관관계 회귀식을 현장 계측기에 적용한 결과, 계측기에서 측정되는 용적수분함량과 EC<sub>b</sub>를 매개변수로 활용하여 EC<sub>e</sub>를 계측할 수 있었다. 따라서, 향후 염농도 자동계측기를 활용하면 토양 EC<sub>e</sub>의 장기 변동을 모니터링할 수 있으며, 이와 같은 시간에 따른 EC<sub>e</sub> 변화양상을 활용하여 목표 EC<sub>e</sub> 수준까지 제염되는 기간을 예측할 수 있을 것으로 기대된다.
Everolimus-Eluting Stent Implantation for Unprotected Left Main Coronary Artery Stenosis
PRECOMBAT-2 Investigators,Kim, Y.H.,Park, D.W.,Ahn, J.M.,Yun, S.C.,Song, H.G.,Lee, J.Y.,Kim, W.J.,Kang, S.J.,Lee, S.W.,Lee, C.W.,Park, S.W.,Jang, Y.,Jeong, M.H.,Kim, H.S.,Hur, S.H.,Rha, S.W.,Lim, D.S. Elsevier 2012 JACC. Cardiovascular interventions Vol.5 No.7
Objectives: This study sought to evaluate the safety and efficacy of second-generation drug-eluting stents (DES) for patients with unprotected left main coronary artery (ULMCA) stenosis. Background: The clinical benefit of second-generation DES for ULMCA stenosis has not been determined. Methods: The authors assessed 334 consecutive patients who received everolimus-eluting stents (EES) for ULMCA stenosis between 2009 and 2010. The 18-month incidence rates of major adverse cardiac or cerebrovascular events (MACCE), including death, myocardial infarction (MI), stroke, or ischemia-driven target vessel revascularization (TVR), were compared with those of a randomized study comparing patients who received sirolimus-eluting stents (SES) (n = 327) or coronary artery bypass grafts (CABG) (n = 272). Results: EES (8.9%) showed a comparable incidence of MACCE as SES (10.8%; adjusted hazard ratio [aHR] of EES: 0.84; 95% confidence interval [CI]: 0.51 to 1.40; p = 0.51) and CABG (6.7%, aHR of EES: 1.40; 95% CI: 0.78 to 2.54; p = 0.26). The composite incidence of death, MI, or stroke also did not differ among patients receiving EES (3.3%), SES (3.7%; aHR of EES: 0.63; 95% CI: 0.27 to 1.47; p = 0.29), and CABG (4.8%; aHR of EES: 0.67; 95% CI: 0.29 to 1.54; p = 0.34). However, the incidence of ischemia-driven TVR in the EES group (6.5%) was higher than in the CABG group (2.6%, aHR of EES: 2.77; 95% CI: 1.17 to 6.58; p = 0.02), but comparable to SES (8.2%, aHR of EES: 1.14; 95% CI: 0.64 to 2.06; p = 0.65). Angiographic restenosis rates were similar in the SES and EES groups (13.8% vs. 9.2%, p = 0.16). Conclusions: Second-generation EES had a similar 18-month risk of MACCE for ULMCA stenosis as first-generation SES or CABG. (Evaluation of Outcomes of EES Implantation for Unprotected Left Main Coronary Artery Stenosis [PRECOMBAT-2]; NCT01348022)
이주희<SUP>1<,SUP>,이규언<SUP>1,2<,SUP>,박경식<SUP>1,2<,SUP>,구도훈<SUP>1,2<,SUP>,오승근<SUP>1<,SUP>,윤여규<SUP>1,2<,SUP>,Ju Hee Lee,M,D,<SUP>1<,SUP>,Kyu Eun Lee,M,D,<SUP>1,2<,SUP>,Kyung Sik Park,M,D,<SUP>1,2<,SUP>,Do 대한갑상선-내분비외과학회 2008 The Koreran journal of Endocrine Surgery Vol.8 No.3
<B>Purpose:</B> Medullary thyroid carcinoma (MTC) is an uncommon thyroid tumor and the clinical course is variable. Many prognostic factors for MTC have been studied, but the significance of some of these factors remains con</B>troversial. This study aimed to evaluate the prognosis of recurrent disease in patients suffering with MTC. <P><B>Methods: </B>Fifty three patients who were operated for MTC from 1987 to 2006 in Seoul National University Hospital (SNUH) was retrospectively analyzed. Their medical records were reviewed for the demographic data, the laboratory data and the clinical course, the treatment and the long-term outcome. The median duration of follow-up was 66.5 months. Forty-two patients who were operated on primarily in this hospital were analyzed for their recurrence free survival. <P><B>Results:</B> The mean age atdiagnosis was 41.8 years. There were 28 femaleand 25 male patients. Eleven patients (22.9%) had multifocal disease. There were 32 sporadic MTC patients, 15 MEN2A patients, 3 familial medullary thyroid carcinoma (FMTC) patients and 1 MEN 2B patient. The 10- and 15-year overall survival rates were 91.9% and 76.5%, respectively; the 5- and 10-year recurrence-free survival rates were 70.6% and 45.5%, respectively. By univariate statistical analysis, the stage (stage I/II vs. III/IV, P= 0.025), extrathyroidal extension (P=0.039), cervical lymph node metastasis (P=0.044), and the postoperative calcitonin level (≥25 pg/ml) (P=0.003) were the significant factors that influenced recurrence. <P><B>Conclusion:</B> The overall prognosis of MTC is favorable. The significantfactors for a poor prognosis were the presence of lymph node metastasis, TNM stage III and IV, positive extrathyroidal extension at the first diagnosis and a high postoperative calcitonin level.<B> (Korean J Endocrine Surg 2008;8:183-188)</B>
Influence of Sodium Hyaluronate Concentration on Corneal Aberrations in Soft Contact Lens Wearers
Jong Soo Lee,Jong Moon Park,Hyun Kyung Cho,Su Jin Kim,Hyoun Do Huh2,Young Min Park 대한안과학회 2018 Korean Journal of Ophthalmology Vol.32 No.2
Purpose: This study aimed to evaluate the influence of varying concentrations of sodium hyaluronate (SH) eye drops on corneal aberrations in normal individuals wearing silicone hydrogel contact lenses. Methods: Normal individuals wearing silicone hydrogel contact lenses were enrolled in this study. Subjects were classified into two groups depending on the concentration of the preservative-free SH used (group 1, 0.1% SH; group 2, 0.3% SH). All subjects were asked to blink five times after instillation of the SH eye drop and before the Galilei measurements. Corneal aberrations were measured over the contact lenses before and after SH eye drop instillation. Visual acuity (VA) over the contact lenses was also measured both before instillation of the SH eye drop and after the subjects completed the five blinks. Results: There was no change in VA after SH instillation in group 1; however, group 2’s VA significantly deteriorated after SH instillation. Changes in VA after SH instillation compared to baseline were significantly higher in group 2 than in group 1. Similarly, the increase in corneal aberrations after SH instillation was significant in group 2 but not significant in group 1. Among the significantly increased corneal aberration parameters, defocus was the main type in group 2. Changes in corneal aberrations after SH instillation compared to baseline were significantly higher in group 2 than in group 1. Conclusions: A 0.3%-concentration of SH increases corneal aberration and decreases VA in soft contact lens wearers. Defocus is the main type of aberration that increased in the 0.3% SH instillation group.
갑상선질환에서 Sonic Hedgehog 단백질 발현의 임상적 의의
유근수,이옥준<SUP>1<,SUP>,김원재<SUP>2<,SUP>,박성수,김동주,박진우,최재운,장이찬,OrloH,Clark<SUP>3<,SUP>,Kuhn-Soo Ryu,M,D,Ok-Jun Lee,M,D,<SUP>1<,SUP>,Wun-Jae Kim,M,D,<SUP>2<,SUP>,Sung Su Park,M,D,Dong-Ju Kim,M,D,Jin- Woo Park 대한갑상선-내분비외과학회 2011 The Koreran journal of Endocrine Surgery Vol.11 No.4
Purpose: The Hedgehog (Hh) signaling pathway is important in embryonic development including cell differentiation and proliferation. Recently, activation of this pathway has been implicated in several forms of solid cancers. We investigated sonic hedgehog (Shh) protein expression and its relation to differentiation and clinicopathologic characteristics in thyroid cancer cell lines and tissues. Methods: We used five thyroid cancer cell lines: TPC-1, FTC-133, FTC-236, FTC-238, and XTC-1. We made tissue microarray slides using 80 thyroid surgical specimen: 40 benign and 40 malignant lesions. Immunohistochemical staining was performed using anti-Shh antibody. mRNA expression of NIS, thyroglobulin, and CD97 were evaluated by RT-PCR. Cyclopamine was used as a Shh signal inhibitor. Results: Shh expression was more prominent in TPC-1, FTC-133, and XTC-1 cell lines than the others. Cyclopamine downregulated CD97 and upregulated thyroglobulin mRNA expression, but did not induce mRNA expression of NIS. Thyroid tissues showed varied expression of Shh in both benign and malignant diseases. Shh expression was detected in 38 of 50 (76%) normal, in 18 of 25 (72%) non-neoplastic benign, in nine of 15 (60%) benign tumors, and in 31 of 40 (77%) malignant tumors. Shh over-expression was significantly less frequent in papillary thyroid carcinomas than in normal or benign thyroid tissues. In addition, Shh protein expression did not relate to clinicopathologic characteristics in papillary thyroid carcinomas. Conclusion: Thyroid tissues and cell lines vary in expression of Shh. Cyclopamine can induce redifferentiation in thyroid cancer cell lines. Shh protein expression, however, is unrelated to clinicopathologic characteristics in papillary thyroid carcinomas. (Korean J Endocrine Surg 2011;11:234-241)