정상 한국인에서 연령증가에 따른 혈장 Dehydroepiandrosteronesulfate ( DHEA-S ) 농도 및 DHEA - S / cortisol 비의 변화

박성우,유형준,임성희,최문기,유재명,박민숙,이권엽,박철수,김철홍,김현규,김두만,박규용 대한내분비학회 1997 Endocrinology and metabolism Vol.12 No.2

Backgroud: DHEA-S is the most abundant steroid hormone in circulation, and primarily secreted from the adrenal cortex, but its physiological role is little known. One of the characteristic features of DHEA-S is progressive decrement of plasma DHEA-S level with advancing age, in contrast, plasma levels of other adrenal hormones are not chaging or littie decreasing. To grasp the trends of plasma DHEA-S level and DHEA-S/cortisol ratio by age in healthy Korean, we measured the plasma DHEA-S levels and DHEA-S/cortisol ratios in healthy Korean. Methods: Healthy Korean(men: 99, women: 102, age range: 15-97 year old)were studied. Subjects were not taking drugs(such as glucocorticoid or androgenic medication) or cigarettes known to modify the plasma level of DHEA-S and cortisol, and had no evidence of hepatic, renal disease or hyperlipidemia as determined by serum lipid, bilirubin, SGOT, SGPT, BUN, creatinine. Data were analyzed by 10-year age group for men and women: i.e, 10-19, 20-29, 30-39, 40- 49, 50-59, 60-69, 70-79, 80-89 and 90 year or more. Plasma DHEA-S levels were measured by using a commercially available RIA kit with 125I labeled-DHEA-SO4(Coat-A Count DHEA-SO4), and for the measurement of plasma cortisol levels, commercial Gamma Coat TM[125I] Cortisol Radioimmunassay Kit was used. Results:. 1) In both men and women, plasma DHEA-S level showed high interindividual variation within the same age group. 2) There were individual sex differences in plasma levels of DHEA-S, in all age groups, plasma DHEA-S levels were significantly higher values for men than for women. 3) Maximum plasma DHEA-S levels(men; 237+-3.35 ug/dL, women; 108+-17.5 ug/dL) were at third decade in both men and women. 4) Both men and women showed the continuous decline in plasma DHEA-S level with age. These age-related decline was more prominent in men than in women(men; y= -3.152 * +292.6, r2= 0.8459, P$lt;0.05, women; y= -1.417 * +143.3, r2 = 0.7278, P$lt; 0.05). 5) As an index of aging, there was no stastical difference between DHEA-S and DHEA- S/cortisol ratio. Conclusion: In healthy Korean, there were high interindividual variation of plasrna DHEA-S levels. In both men and women plasma DHEA-S level was peak at third decade, and from when it declined progressively with age. These results suggest that although the reliability of single plasma DHEA-S measurement are limited, the decline of DHEA-S with advancing age might be a specific marker of endocrinologic hormonal milieu(aging index). Also, concerning to individual adrenal secreting capacity, we measured DHEA-S/cortisol ratio. But we did not found that plasma DHEA-S/cortisol ratio is superior to the plasma DHEA-S level as an aging index. (J Kor Soc Endocrinol 12:245-254, 1997)

단무지 공장에서 발생한 질식 사고의 원인과 방사선학적 소견: 중례보고 및 가스분석 결과

박충기,김만구,김흥철,안범규,박만수,황우철,최철순,강익원 江原大學校 附設 環境硏究所 1994 環境硏究 Vol.11 No.-

목 적:단무지 공장에서 질식사고를 일으켰던 가스의 종류를 알아내고, 이러한 가스중독의 방서선학적 소견을 소개하기 위하여 본 연구를 하였다. 대상 및 방법:단무지 공장에서 발생한 질식 사고자 3예중 생존자 1예를 대상으로 단순흥부X-선검사와 CT 소견을 분석하였으며, 가스의 종류를 알아내기 위하여 단무지를 유리병에 넣어 발생된 가스를 가스크로마토그래픽을 이용하여 분석하였다. 결 과:단무지 공장에서 발생한 질식사고자중 생존한 1명의 방사선학적 검사에서 신속히 호전되는 폐경결(consolidation)을 볼 수 있었으며 이는 폐부종의 소견임을 알 수 있었다. 협기성 상태에서 단무지를 담은 유리병의 상층부 가스를 실험 분석한 결과 이산화탄소, 에칠알코올이 다량으로 검출되었으나 독성가스는 주로 황화수소이였다. 결 론:단무지 공장의 질식 사고자에서 폐방사선학적 소견은 폐경결을 보이는 폐부증으로서 이는 실험을 통해 단무지에서 발생되는 유독가스인 황화수소 때문임을 입증하였다. Purpose: To identify the main toxic gas released from salted radish in rice bran(Dan-M-Ji) and to introduce the radiological findings of the patient who was exposed to the gas. Materials and Methods: Chest radiographs and CT scans of one survivor among three men who were exposed to the gas from Dan-Mu-Ji were reviewed. Gas obtained from the closed bottle containing Dan-Mu-Ji was analized by using the gas chromatography. Results: The radiographlc examinations of the survivor were suggestive of pulmonary edema with it's rapidly improving consolidations in both lung. The headapace gas within the bottle containing Dan-Mu-Ji was mainly composed with carbon dioxide, ethyl alcohol and hydrogen sulfide, of which hydrogen sulfide was considered the main toxic gas released. Conclusion: Under the anaerobic condition, Dan-Mu-Ji released toxic hydrogen sulfide. Inhalation of hydrogen sulfide might produce non-cardiogenic pulmonary edema.

축구선수와 일반인의 스쿼트운동에 따른 근피로도 변화 비교

박수경(Soo Gyeong Park),이만기(Man Gi Lee),김현준(Hyun Jun Kim) 한국사회체육학회 2010 한국사회체육학회지 Vol.0 No.41

In this study, to analyze the changing process of the muscle fatigue before squat, immediately after squat, 5 minutes after squat, 10 minutes after squat, experiment was carried out to 8 people of soccer player played over 7 years who are at I university and 8 people of healthy adult man. The electromyogram was measured at Erector Spinae, Gluteus Maximus and Rectus Femoris, and repeated 2-way ANOVA test was performed by repeated measuring about the value of the muscle fatigue of each muscle and time, group, left and right side, time and group, time and left and right side. The results are as below. About the left and right side of the Erector Spinae, Gluteus Maximus and Rectus Femoris, there is no meaningful difference through all 3 kind of muscles. In the result of the analysis of the study about the Erector Spinae and Rectus Femoris, there are statistically definite differences through time and a little statistical difference through time and group. But about the Gluteus Maximus, there is no statistically meaningful difference. Thus, the muscle fatigue generated in the process of squat, influences on the muscle of Erector Spinae and Rectus Femoris but doesn`t influence on the Gluteus Maximus.

프랑스의 문화외교 : 명성외교에서 영향력외교로

조만수(CHO Man-Soo),박선희(PARK Sunhee) 한국프랑스문화학회 2021 프랑스문화연구 Vol.50 No.1

Cette thèse divise l’orientation de la diplomatie culturelle française de la fin du XIXe siècle à nos jours en trois périodes. De 1880 à la fin des années 1970, la France a poursuivi une stratégie de maintien de son ancienne réputation par la diplomatie culturelle, malgré le fait qu’elle n’était pas une superpuissance. L’Allemagne après la défaite de la Première Guerre mondiale et l’Espagne, qui ont été économiquement dévastées après la Seconde Guerre mondiale, sont des exemples de renforcement de la publicité nationale et de la diplomatie culturelle dans la période de déclin national. Cependant la France qui a consacré beaucoup de temps à la diplomatie culturelle de 1880 à la fin des années 1970 est clairement exceptionnel. Au milieu des changements de l’ordre mondial néolibéral des années 1980 à la fin des années 2000, la France utilise une stratégie de diplomatie culturelle défensive pour protéger son industrie culturelle. Inventant le concept d’exception culturelle et de diversité culturelle, elle cherche à protéger les intérêts français à travers des réseaux diplomatiques multilatéraux incluant des organisations internationales. Après 2008, utilisant le nouveau terme de « diplomatie d’influence », la France a établi et justifié la diplomatie culturelle comme une relation mutuellement bénéfique avec ses homologues, et a réformé le système de diplomatie culturelle afin de mettre en œuvre des stratégies efficaces de diplomatie culturelle. La diplomatie culturelle, qui était dirigée par le ministère des Affaires étrangères, peut être menée par des institutions sous tutelle du ministère des Affaires étrangères, mais avec autonomie, tout en laissant progressivement à un groupe d’experts externes de prendre les devants. A ce titre, cet article entend considérer l’orientation stratégique du maintien, du renforcement ou de la réalisation de sa position sur la scène internationale par la culture alors que la France, qui a régné en tant que superpuissance mondiale, a connu une période de déclin de la puissance nationale du XIXe siècle au présent.

籠球 運動과 撓骨 및 中手骨 成長과의 關係

박인기,백만수,박진권 충남대학교 1996 忠南科學硏究誌 Vol.23 No.1

The effects of basketball training on the structural aspects of the radius and metacarpal have been analyzed. Research sample groups consist of a player group and a general student group. The player group consists of 48 students whose grade varies from the fifth grade of primary school to the second grade of boys' high school. They had been regularly trained 3 days (6 hours) per week. The general students group consists of 60 students who did not participate in the training. From these comparative study, we have found that noticeable growth of the redius proximal end and distal end of the player group had occurred from the time of the first grade of middle school which was the third year of training. We also found little difference in the growth of the redius shaft. Notable growth of the metacerpal proximal and distal end as in the radius has been abserved from the time of the first grade of middle school. Noticeable growth of the third metacarpal shaft had occurred from the time of the sixth grade of primary school which was the second year of training. The second, fourth, fifth metacarpal shaft had growed noticeably from the time of the first grade of high school which was the sixth year of training.

다양한 파장폭의 가시광선에 의해 중합된 복합레진의 미세경도와 변연누출도

박수만,이재용,한승렬,하상윤,신동훈 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.4

Several ways of curing are being tried to improve material's properties and reduce marginal gap. However, all are considering about the pattern of light intensity. It was noted from the preliminary study the change of light wavelength from filter chaning may give an impact on material's property and microleakage. The object of this study was to verify the effect of filters with various wavelength width on the microhardness and microleakage of composite resin; hybrid type of DenFil and submicron hybrid type of Esthet X. Composite resins were cured using 3 kinds of filter; narrow-banded(465-475 nm), mid-banded(430-470 nm), wide-banded(400-500 nm). After the estimation of microhardness, degree of dye penetration and the maximum gap from SEM evaluation were done between 4 groups that showed no difference in microhardness value of the lower surface. The results were as follows: 1. Adequate microhardness could not be gained with a narrow-banded filter irrespective of curing time. At the upper surface. DenFil should be polymerized with middle or wide-banded filter for 20 seconds at least, while Esthet X be cured with middle or wide-banded filter for 30 seconds at least to get similar hardness value to control group. 2. There was little dye penetration in enamel margin, but all dentin margins showed much more dye penetration irrespective of curing conditions. Although there was not statistical difference, groups cured with mid-banded filter for 40 seconds and with wide-width filter for 20 seconds showed relatively less dye penetration. 3. It was revealed from the SEM examination that group cured with wide-banded filter had the smallest gap without statistical significance. Spearman's rho test showed that the correlation between the results of dye penetration and SEM examination was very low. From these results, it could be concluded that curing with wide-width filter would be better than the other techniques. even though the curing technique using mid-width filter seems to have its own unique advantage.

우리말의 기본월 연구

박만수 동아대학교 어학연구소 1989 언어와 언어교육 Vol.4 No.-

방편말의 의미

박만수 동아대학교 어학연구소 1990 언어와 언어교육 Vol.5 No.-

Instrumentals are Case-constituents realized by 'Noun+Particles'. Their semantic system is established in relation with the syntactic circumstances of Predicates in sentence. In general, Instrumentals includes two sub-systems : 1) Inchoative, 2) Resultatie meanings. The Inchoative meanings are expressed by the following syntactic patterns : (1) NP-i + NP-ro+NP-eul+Predicate (2) NP-i + NP-ro+NP-hago+Predicate (3) NP-i + NP-hago+NP-ro++NP+eul+Predicate The Inchoative meanings are sub-divided as indicatiors of Instrument, Material, Means and Cause. 2) The Resultive meanings are expressed by the following syntactic patterns : (1) NP-i + NP-eseo+NP-ro+Predicate (2) NP-i + NP-eul+NP-ro+Predicate (3) NP-i + NP+ro+Predicate (4) NP+i + NP-hago+NP-eseo+NP-ro+Predicate (5) NP+i + NP-hago+NP-eul+NP-ro+Predicate The Resultative meanings are sub-divided as indicators of Direction, Transform, Capacity and Time. ※ ●-i→Subject mark ●-eseo→Locative mark ●-eul→Object mark ●-hago→Commitative mark ●-ro→Instrumental mark

膀胱 移行上皮細胞癌에 있어서 核DNA Ploidy測定의 意義

朴晩洙,薛鍾求 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

From January 1986 to December 1992, reviewed 80 transitional cell carcinoma of bladder in the Department of Urology, Chungnam National University Hospital. DNA ploidy was analyzed with FCM(flow-cytometry) according to cellular differentiation, tumor stage, recurrence rate and invasiveness. The results are as followings : 1. Tumor grades were 8 cases in grade Ⅰ, 30 cases in grade Ⅱ, 38 cases in grade Ⅲ and 4 cases in grade Ⅳ. And tumor stages were 45 cases in stage A, 28 cases in stage B, 5 cases in stage C and 2 cases in stage D. 2. In 80 transitional cell carcinoma of bladder, 41 tumors(51.2%) were diploid stem line, 39 tumors(48.8%) were aneuploid stem line. DNA ploidy according to tumor grade, incidence of aneuploid was 17% (1/8) in grade Ⅰ, 23 % (7/30) in grade Ⅱ, 71 % (27/38) in grade Ⅲ and 100 % (4/4) in grade Ⅳ. The incidence of aneuploid was increased with tumor grading(low grade;21.1%, high grade; 73.8%) (P<0.001). And DNA ploidy according to tumor stage, incidence of aneuploid was 31.1%(14/45) in superficial transitional cell carcinoma of bladder group, and 71.4%(25/35) in invasive and metastatic transitional cell carcinoma of bladder group(P<0.001). 3. In superficial transitional bladder carcinoma, recurrence rates according to tumor grade were 2.55 in low grade group, 5.69 in high grade group(P<0.01), and recurrence rates according to the DNA ploidy were 2.38 in diploid group and 5.04 in aneuploid group(P<0.05). 4. In recurred superficial transitional bladder carcinoma, invasion rates according to the cellular grade were 15.4%(2/13) in low grade group, 62.5%(5/8) in high grade group(P>0.05), and invasion rates according to the DNA ploidy were 16.7% (2/12) in diploid group and 55.6%(5/9) in aneuploid group(P>0.5).

토씨「에」의 연구

박만수 동아대학교 국어국문학과 1985 국어국문학 Vol.6 No.-