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Zeynep Nur Orhon,Sibel Devrim,Melek Celik,Yekbun Dogan,Asif Yildirim,Erem Kaan Basok 대한마취통증의학회 2013 Korean Journal of Anesthesiology Vol.64 No.3
Background: The aim of the study was to evaluate the comparative effects of propofol infusion versus sevoflurane for maintenance of anesthesia with respect to hemodynamics, recovery characteristics, nausea and vomiting in patients undergoing percutaneous nephrolithotomy. Methods: Forty American Society of Anesthesiologists physical status I-II patients, aged between 22 and 65 years were randomly divided to receive either intravenous anesthesia with propofol (group P) or sevoflurane (group S). Cardiovascular variables, peripheral oxygen saturation (SpO2), end-tidal carbon dioxide (ETCO2), bispectral index (BIS) and train-of-four (TOF) values were recorded at intervals throughout the procedure. Time to spontaneous respiration, eye opening, extubation, obey commands, hand squeezing, Aldrete Score > 9 and the incidence of postoperative nausea and vomiting were recorded. Results: Early recovery times [spontaneous respiration (P = 0.002), eye opening (P = 0.006), extubation (P = 0.013), obey commands (P < 0.05), hand squeezing (P = 0.005)] were significantly longer in group P. The incidence of vomiting was significantly higher in group S (P < 0.05). Hemodynamic parameters, levels of SpO2, ETCO2, and BIS and TOF values were not significantly different between the groups (P > 0.05). Conclusions: The present study which adjusted sevoflurane concentration and propofol infusion rate according to BIS values revealed that maintenance of anesthesia with sevoflurane is associated with faster recovery than anesthesia with propofol. Propofol resulted in a significantly lower incidence of postoperative nausea and vomiting. Hemodynamic parameters and levels of SpO2 and ETCO2 were comparable between the groups during percutaneous nephrolithotomy.
Epidural anesthesia for pilonidal sinus surgery: ropivacaine versus levobupivacaine
Zeynep Nur Orhon,Emine Nursen Koltka,Sibel Devrim,Sevil Tüfekçi,Serkan Doğru,Melek Çelik 대한마취통증의학회 2015 Korean Journal of Anesthesiology Vol.68 No.2
Background: Epidural anesthesia is one of the best options for lower abdominal and lower limb surgery. However, therehave been insufficient reports regarding the use of epidural anesthesia for pilonidal sinus surgery. The present study wasperformed to compare the clinical profiles of epidural block performed with 0.75% levobupivacaine and 0.75% ropivacainein this procedure. Methods: Thirty patients undergoing pilonidal sinus surgery were randomly allocated into two groups: one group receivedlevobupivacaine and the other received ropivacaine at 0.75% in a volume of 10 ml. Arterial blood pressure, heartrate, oxygen saturation, the onset time of analgesia and duration of block, highest sensory block level, perioperative andpostoperative side effects, and patients’ and surgeons’ satisfaction were recorded. Results: Hemodynamic stability was maintained in both groups throughout surgery. The onset time of analgesia (thetime from epidural injection of local anesthetic to reach L2 sensorial block) was 6.26 ± 3.49 min in the levobupivacainegroup and 4.06 ± 1.75 min in the ropivacaine group (P = 0.116). The duration of sensorial block (time for regression ofsensory block to L2) was 297.73 ± 70.94 min in group L and 332.40 ± 102.22 min in group R (P = 0.110). Motor block wasnot seen in any of the patients in the study groups. Patients’ and surgeons’ satisfaction with the anesthetic technique weremostly excellent in both groups. Conclusions: In patients undergoing pilonidal sinus surgery, both levobupivacaine and ropivacaine produce rapid andexcellent epidural block without leading to motor block or significant side effects. Although not statistically significant,the onset time of anesthesia was shorter and the duration of effect was longer with ropivacaine than with levobupivacainein this study.