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Ostad Andisheh Norouzian,Barghchi Hanieh,Jangjoo Ali,Ranjbar Golnaz,Rezvani Reza,Bahrami Leila Sadat,Goshayeshi Ladan,Khadem-Rezaiyan Majid,Nematy Mohsen 한국임상영양학회 2021 Clinical Nutrition Research Vol.10 No.4
Decreased food intake is an effective mechanism for gastric bypass surgery (GBS) for successful weight loss. This cross-sectional study aimed to assess dietary intake, micro-and macro-nutrients in the patients undergoing GBS and determine the possible associations with weight changes. We assessed anthropometric indices and food intake at 24 month-post gastric bypass surgery. Dietary data was evaluated using three-day food records. After the 24 months of surgery, among 35 patients (mean age: 43.5 ± 11.2 years; 82.85% females), with the mean body mass index (BMI) of 30.5 ± 4.5 kg/m2, 17 cases were < 50% of their excess weight. The average daily calorie intake was 1,733 ± 630 kcal, with 14.88% of calories from protein. Consumption amounts of protein (0.82 ± 0.27 g/kg of the current weight), as well as fiber, and some micro-nutrients (vitamin B9, E, K, B5, and D3) were lower than recommended amounts. Patients were classified into three groups based on their success in weight loss after surgery. Calorie intake was not significantly different between groups, but successful groups consumed considerably more protein and less carbohydrate than the unsuccessful group (p < 0.05). Based on our findings, the patients undergoing GBS had inadequate macro- and micro-nutrient intake after 24 months. However, protein intake can affect patients' success in achieving better weight loss. Long-term cohort and clinical studies need to be conducted to comprehend this process further.
Kaveh Ostad-Ali-Askari,Mohammad Shayannejad,Hossein Ghorbanizadeh-Kharazi 대한토목학회 2017 KSCE JOURNAL OF CIVIL ENGINEERING Vol.21 No.1
Excessive use of chemical fertilizers, especially nitrogen fertilizers to increase crop and improper purification, and delivery of municipal and industrial wastewater are proposed as factors that increase the amount of nitrate in groundwater in this area. Thus, investigation of nitrate contamination as one of the most important environmental problems in groundwater is necessary. In the present study, modeling and estimation of nitrate pollution in groundwater of marginal area of Zayandeh-rood River, Isfahan, Iran, was investigated using water quality and artificial neural networks. 100 wells (77 agriculture well, 13 drinking well and 10 gardens well) in the marginal area of Zayandeh-rood River, Isfahan, Iran were selected. MATLAB software and three-layer Perceptron network were used. The back-propagation learning rule and sigmoid activation function were applied for the training process. After frequent experiments, a network with one hidden layer and 19 neurons make the least error in the process of network training, testing and validation. ANN models can be applied for the investigation of water quality parameters.
Fatemeh Heydari,Amir Maghsoudipour,Mohsen Ostad Shabani,Zohreh Hamnabard,Sajad Farhangdoust 한양대학교 세라믹연구소 2014 Journal of Ceramic Processing Research Vol.15 No.1
The objective of the present work is to study properties of a composite material consisting of zirconia nanoparticles in a glass matrix based on the system of BaO-CaO-SiO2-B2O3-Al2O3. Zirconia nanoparticles are added by 0-20 vol.% into the glass matrix to prepare the glass composites. Coefficient of thermal expansion, glass transition temperature and dilatometric softening point temperature of specimens are determined by means of dilatometry analysis. Coefficient of thermal expansion of base glass is 10.38 × 10−6 k−1 and by increasing zirconia content to 10, 15, and 20 vol.%, coefficient of thermal expansion reduces down to 9.88 × 10−6 , 9.84 × 10−6 and 9.76 × 10−6 k−1 respectively. Sinterability of different specimens is studied by increasing zirconia nanoparticles. Electrical properties are measured in different temperatures, and results show that with increment of zirconia nanoparticles, temperature resistivity of specimens has been decreased. Microstructural investigation reveals a well-adhered bonding between the sealants and electrolyte.
Montazeri, Hamed,Bouzari, Saeid,Azadmanesh, Kayhan,Ostad, Seyed Nasser,Ghahremani, Mohammad Hossein Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.17
Cyclin E, a key coordinator of the G1 to S transition in the cell cycle, may be deregulated in several malignancies, including breast cancer. The most significant aberration in cyclin E is its elastase mediated proteolytic cleavage into tumor specific low molecular weight isoforms (LMW-Es). LMW-Es are biochemically hyperactive and biologically drive tumorigenesis in transgenic mouse models. Additionally, expression of LMW-Es has been correlated with poor survival in breast cancer cases. Here we determine whether expression of LMW-Es in a breast cancer cell line that is naturally devoid of these deregulated forms would alter their progression through each phase of the cell cycle. The results revealed that LMW-Es expression resulted in an increased doubling time, concomitant with a predominant increase in the population in the S phase of the cell cycle. Moreover, downregulation of p53 in LMW-Es cells resulted in additional shortening of the doubling time and enrichment of cells in the S and G2/M phases of the cell cycle. Furthermore, expression of LMW-Es sensitized cells to ${\beta}$-estradiol (E2) mediated growth and changed expression patterns of estrogen receptor and Bcl-2. Intriguingly, expression of LMW-Es could surpass anti-apoptotic effects raised by p53 upregulation. Taken together these studies suggest that overexpression of LMW-Es in collaboration with p53 loss results in altered g rowth properties of MCF-7 cells, enhancing the oncogenic activity of these ER positive breast cancer cells.