Effects of Varying Levels of Whole Cottonseed on Blood, Milk and Rumen Parameters of Dairy Cows

Oguz, F. Karakas,Oguz, M.N.,Buyukoglu, T.,Sahinduran, S. Asian Australasian Association of Animal Productio 2006 Animal Bioscience Vol.19 No.6

Four lactating Holstein cows were used in a $4{\times}4$ Latin-square design to determine the effects of various levels of whole cottonseed (WCS) in diets on parameters including milk (yield and fat content), rumen fluid (pH, ammonia and TVFA) and blood (${\beta}$-carotene, vit. A, vit. E, urea, $NH_3$, Ca, P and Mg levels). Cows consumed 0, 1, 2 or 3 kg WCS per day. No significant differences were observed among the groups on analysed parameters except plasma vitamin E concentration. In addition, when the amount of cottonseed was increased, milk yield and milk fat content also tended to increase but this increase was not statistically significant. In conclusion, feeding of WCS up to 3 kg per day with ad libitum maize silage did not cause negative effects on milk yield, milk fat and blood vitamin levels in the short term in dairy cows.

Effects of Surface Shapes and Geotechnical Conditions on the Ground Motion

Oguz Akin Düzgün,Ahmet Budak 대한토목학회 2015 KSCE JOURNAL OF CIVIL ENGINEERING Vol.19 No.5

The influences of surface geometry and local soil properties on ground motion are parametrically studied. The system response is numerically evaluated. In the modelling, finite and infinite elements are applied. Three types of topography (single-faced slopes, canyons and ridges) are taken into account. According to the results, topographic conditions, depth of the rigid bedrock and geotechnical properties have significance in the alteration of ground motion at the irregular soil surface and its surroundings. For all selected surface shapes, the most critical cases occur at top corners especially when the slope gets steeper. These cases are independent on the natural period of structures. The results correspond with those earthquakes where topographical effects are observed and could be seemed to be worthwhile from the perspective of earthquake engineering and seismology.

A study on the topographical and geotechnical effects in 2-D soil-structure interaction analysis under ground motion

Oguz Akin Düzgün,Ahmet Budak 국제구조공학회 2011 Structural Engineering and Mechanics, An Int'l Jou Vol.40 No.6

This paper evaluates the effects of topographical and geotechnical irregularities on the dynamic response of the 2-D soil-structure systems under ground motion by coupling finite and infinite elements. A numerical procedure is employed, and a parametric study is carried out for single-faced slope topographies. It is concluded that topographic conditions may have important effects on the ground motion along the slope. The geotechnical properties of the soil will also have significantly amplified effects on the whole system motion, which cannot be neglected for design purposes. So, dynamic response of a soil-structure systems are primarily affected by surface shapes and geotechnical properties of the soil. Location of the structure is another parameter affecting the whole system response.

Effects of Lycopene Alone or Combined with Melatonin on Methotrexate-Induced Nephrotoxicity in Rats

Oguz, Elif,Kocarslan, Sezen,Tabur, Suzan,Sezen, Hatice,Yilmaz, Zehra,Aksoy, Nurten Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.14

Methotrexate (Mtx), used for its anticancer and immunsuppresive properties, is known to be a nephrotoxic agent. We aimed to investigate the effects of lycopene (Lyc) alone or combined with melatonin (Mel) on Mtxinduced nephrotoxicity since both of these agents have antioxidant and anti-inflammatory effects. Nephrotoxicity was induced by intraperitoneal administration of methotrexate at a dose of 20 mg/kg. Treatment both with Lyc alone and Lyc combined with Mel provided significant reduction in tumor necrosis factor-alpha, interleukin 1-beta and ceruloplasmin levels in Mtx administered rats. Hovewer, Lyc combined with Mel provided a significant reduction also in NO levels. Hstopathological examination showed that there was an obvious improvement in the degenerative changes compared to Mtx administrated group with the Lyc combined Mel group giving best protection. In conclusion Lyc alone and combined with Mel provided significant improvement against renal damage caused by Mtx, preseumably via antioxidant and anti-inflammatory activities.

Hepatitis B and C Seroprevalence in Solid Tumors - Necessity for Screening During Chemotherapy

Oguz, Arzu,Aykas, Fatma,Unal, Dilek,Karahan, Samet,Uslu, Emine,Basak, Mustafa,Karaman, Ahmet Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.3

Background: Hepatitis B and C are the leading causes of liver diseases worldwide. For hematological and solid malignancy patients undergoing chemotherapy, increases in HBV DNA and HCV RNA levels can be detected which may result in reactivation and hepatitis-related morbidity and mortality. The aim of this study was to determine the seroprevalence of Hbs ag and Anti HCV positivity in patients with solid malignancies undergoing chemotherapy and consequences during follow-up. Materials and Methods: The files of 914 patients with solid malignancies whose hepatitis markers were determined serologically at diagnosis were reviewed retrospectively. All underwent adjuvant/palliative chemotherapy. For the cases with HBV and/or HCV positivity, HBV DNA and HCV RNA levels, liver function tests at diagnosis and during follow-up and the treatment modalities that were chosen were determined. Results: Of 914 cases, Hbs Ag, anti Hbs and anti HCV positivity were detected in 40 (4.4%), 336 (36.8%) and 26 (2.8%) of the cases respectively. All of the Hbs ag positive patients received prophylactic lamuvidine before the start of chemotherapy. In the Hbs ag and anti HCV positive cases, liver failure was not detected during chemotherapy and a delay in chemotherapy courses because of hepatitis was not encountered. Conclusions: Just as with hematological malignancies, screening for HBV and HCV should also be considered for patients with solid tumors undergoing chemotherapy. Prophylactic antiviral therapy for HBV reduces both the reactivation rates and HBV related mortality and morbidity. The clinical impact of HCV infection on patients undergoing chemotherapy is still not well characterized.

Lack of any Association between Blood Groups and Lung Cancer, Independent of Histology

Oguz, Arzu,Unal, Dilek,Tasdemir, Arzu,Karahan, Samet,Aykas, Fatma,Mutlu, Hasan,Cihan, Yasemin Benderli,Kanbay, Mehmet Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1

Introduction: Lung cancer, the leading cause of cancer deaths, is divided into 2 main classes based on its biology, therapy and prognosis: non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Many cases are at an advanced stage at diagnosis, which is a major obstacle to improving outcomes. It is important to define the high risk group patients for early diagnosis and chance of cure. Blood group antigens are chemical components on erythrocyte membranes but they are also expressed on a variety of epithelial cells. Links between ABO blood groups with benign or malignant diseases, such as gastric and pancreas cancers, have been observed for a long time. In this study, we aimed to investigate any possible relationship between lung cancer histological subtypes and ABO-Rh blood groups. Materials and Methods: The files of 307 pathologically confirmed lung cancer patients were reviewed retrospectively. Cases with a serologically determined blood group and Rh factor were included and those with a history of another primary cancer were excluded, leaving a total of 221. The distribution of blood groups of the lung cancer patients were compared with the distribution of blood groups of healthy donors admitted to the Turkish Red Crescent Blood Service in our city in the year 2012. Results: There was no significant difference between patients with lung cancer of either type and the control group in terms of distribution of ABO blood groups and Rh factor (p: 0.073). There was also no relationship with non small cell cancer histological subtypes. Conclusions: In this study, we found no relationship between the ABO-Rhesus blood groups and NSCLC and SCLC groups. To our knowledge this is the first analysis of ABO blood groups in SCLC patients.

A novel design procedure for tractor clutch fingers by using optimization and response surface methods

Oguz Dogan,Fatih Karpat,Celalettin Yuce,Necmettin Kaya,Nurettin Yavuz,Hasan Sen 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.6

This paper presents a methodology for re-designing a failed tractor transmission component subjected to cyclic loading. Unlike other vehicles, tractors cope with tough working conditions. Thus, it is necessary to re-design components by using modern optimization techniques. To extend their service life, we present a design methodology for a failed tractor clutch power take-off finger. The finger was completely re-designed using topology and shape optimization approach. Stress-life based fatigue analyses were performed. Shape optimization and response surface methodology were conducted to obtain optimum dimensions of the finger. Two design parameters were selected for the design of experiment method and 15 cases were analyzed. By using design of the experiment method, three responses were obtained: Maximum stresses, mass, and displacement depending on the selected the design parameters. After solving the optimization problem, we achieved a maximum stress and mass reduction of 14% and 6%, respectively. The stiffness was improved up to 31.6% compared to the initial design.

Season of Diagnosis and Survival of Advanced Lung Cancer Cases - Any Correlation?

Oguz, Arzu,Unal, Dilek,Kurtul, Neslihan,Aykas, Fatma,Mutlu, Hasan,Karagoz, Hatice,Cetinkaya, Ali Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

Introduction: The influence of season at diagnosis on cancer survival has been an intriguing issue for many years. Most studies have shown a possible correlation in between the seasonality and some cancer type survival. With short expected survival, lung cancer is an arena that still is in need of new prognostic factors and models. We aimed to investigate the effect of season of diagnosis on 3 months, 1 and 2 years survival rates and overall survival of non small cell lung cancer patients. Materials and Methods: The files of non small cell lung cancer patients that were stages IIIB and IV at diagnosis were reviewed retrospectively. According to diagnosis date, the patients were grouped into 4 season groups, autumn, winter, spring and summer. Results: A total of 279 advanced non small cell lung cancer patients' files were reviewed. Median overall survival was 15 months in the entire population. Overall 3 months, 1 and 2 years survival rates were 91.0%, 58.2% and 31.2% respectively. The season of diagnosis was significantly correlated with 3 months survival rates, being diagnosed in spring being associated with better survival. Also the season was significantly correlated with T stage of the disease. For 1 and 2 years survival rates and overall survival, the season of diagnosis was not significantly correlated. There was no correlation detected between season and overall survivals according to histological subtypes of non small cell lung cancer. Conclusion: As a new finding in advanced non small cell lung cancer patients, it can be concluded that being diagnosed in spring can be a favorable prognostic factor for short term survival.

Reliability and Validity of the Turkish Language Version of the International Consultation on Incontinence Questionnaire - Male Lower Urinary Tract Symptoms

Oğuz Mertoğlu,Oktay Üçer,Yasin Ceylan,Ozan Bozkurt,Bülent Günlüsoy,Ali Can Albaz,Ömer Demir,Aegean Study Group of Society of Urological Surgery 대한배뇨장애요실금학회 2016 International Neurourology Journal Vol.20 No.2

Purpose: Patients receiving treatment for benign prostate hyperplasia may have persistent storage symptoms. There has been increasing debate on the precision and accuracy of the International Prostate Symptom Score questionnaires over other questionnaires in evaluating all the complaints of lower urinary tract symptoms (LUTS). The aim of this study was to perform the validity and reliability analysis of the Turkish version of the Internatinal Consultation on Incontinence Questionnaire-Male LUTS (ICIQ-MLUTS). Methods: Linguistic validation was studied (i.e., translation and back translation). Intelligibility was completed between October 2013 and November 2013. Data was collected between November 2013 and March 2014. The stability and reliability of the form were measured with the Cronbach test. Results: In total, 117 male patients were included in the study. At the first visit, the mean age of the patients was 59 years (range, 18–84 years). For reliability, the Cronbach alpha value was 0.798, demonstrating the internal consistency of the form (r>0.7). The internal consistency of each question was examined separately and found to be over 0.7. For the evaluation of test-retest reliability, the test was administered to 116 patients for a second time with an interval of 2–4 weeks. The first and second test scores for each question were found to be correlated (r=0.741). Conclusions: ICIQ-MLUTS is a new questionnaire, which can be used for evaluating male LUTS in Turkey. We believe that the Turkish version of the ICIQ-MLUTS is an important breakthrough in our country.

Design of Coanda Intakes for Optimum Sediment Release Efficiencies

Oğuz Hazar,Sebnem Elçi 대한토목학회 2021 KSCE JOURNAL OF CIVIL ENGINEERING Vol.25 No.2

When the water has to be diverted from a turbid source having a great amount of suspended materials in it, bottom intake structures such as Coanda and Tyrolean types are preferred. To perform this task, diverted water is captured by a transversal rack, and a gallery located in the control crest is utilized. This study was motivated by a search for the best design where the quality of the diverted water can be increased by screening out most of the sediments in the flow. Current work focuses on the water capture and sediment release efficiencies of both Tyrolean and Coanda type intakes through experimental work. It complements and extends existing experimental studies by considering sediment-laden flow. We used a novel sediment feeding system designed specifically for this study in the experiments. Study results pointed out that when sediment release efficiency is considered, all types of Coanda intakes having different design parameters performed better as compared to Tyrolean intakes. Water capture and sediment release efficiencies are related to parameters used in the experiments including Coanda type, rack angle, void ratio, sediment amount, and flow rate based on the statistical analyses of these parameters. An optimum design is proposed with the maximum sediment release efficiency to prevent clogging during the operation of the intakes.