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Nguyen, Van-Toan,Tran, Quoc Chinh,Quang, Nguyen Duc,Nguyen, Ngoc-Anh,Bui, Van-Tien,Dao, Van-Duong,Choi, Ho-Suk Elsevier 2018 Journal of alloys and compounds Vol.766 No.-
<P><B>Abstract</B></P> <P>The improvement of the catalytic performance for methanol and formic acid oxidation reactions remains a key issue for the development of a new generation of direct methanol and formic acid fuel cells. This study reports a simple approach, using selective chemical etching for the synthesis of unique nitrogen-doped carbon dot/Pt<SUB>84</SUB>Pd<SUB>16</SUB> (N-Cdot/Pt<SUB>84</SUB>Pd<SUB>16</SUB>) nano-network structure at room temperature with excellent electrocatalytic properties. The obtained nano-network hybrid material exhibits significant enhancement of the electrocatalytic activity for the electro-oxidation reaction of both methanol and formic acid with current densities of 999.0 and 1919.5 mA/mg<SUB>metal</SUB>, respectively, compared with the commercial ones of 751.32 and 806.02 mA/mg<SUB>metal</SUB>, respectively. Furthermore, the N-Cdot/Pt<SUB>84</SUB>Pd<SUB>16</SUB> nano-network hybrid materials exhibit excellent stability and hydrophilic dispersibility at room temperature.</P> <P><B>Highlights</B></P> <P> <UL> <LI> N-Cdot/PtPd nanonetwork hybrid material is synthesized at room temperature. </LI> <LI> A simple coreduction and a selective chemical etching are applied to the synthesis. </LI> <LI> It generates a nano-network structure with excellent electrocatalytic properties. </LI> <LI> N-Cdot functions as a uniform interconnection between the nanohybrid materials. </LI> <LI> The hybrid exhibits significant enhancement of the activity for both MOR and FAOR. </LI> </UL> </P> <P><B>Graphical abstract</B></P> <P>[DISPLAY OMISSION]</P>
Tung Nguyen-Thach,Nguyen Canh-Hung,Nguyen Van-Duong,Nguyen Thi-Hong-Thuy,Nguyen Van-Lam,Tran Cao-Son,Pham Thi-Minh-Hue 한국약제학회 2020 Journal of Pharmaceutical Investigation Vol.50 No.4
Purpose The study aimed firstly to determine the release behavior of the model drug (berberine chloride) from the dry coated tablets. The second objective of this study was to evaluate the exact location of the dry coated tablets in in vivo. Methods The colon targeting tablets were developed by dry powder coating technique on pan coater. The drug release behavior was determined in the three continuous mediums: pH 1.2; 7.4 and 6.8 plus pectinase. The location of the dry coated tablets in the gastrointestinal tract of human volunteers was observed through the X-ray imaging of the dry coated tablets containing the optimized radiocontrast agents. Results The release kinetics of berberine chloride from the dry coated tablets was mainly controlled by erosion and enzyme sensitive mechanism. The optimum dry coated tablets having the coating powders of pectin 102:HPMC K4 M (2:1) with the coating level of 200%, and the tablet core with BaSO4 10% and iobitridol 30% as radiocontrast agents were observed in the caecum and ascending colon of human volunteers after 5–6 h of oral administration. Conclusion The successful development of these dosage forms is believed to have a high potential in precisely monitoring the release of highly potent drugs such as anti-inflammatory drugs in bowel diseases.
Duong Bich Thuy,Duong Minh Cuong,Campbell James,Nguyen Van Minh Hoang,Nguyen Huu Hien,Bui Thi Bich Hanh,Nguyen Van Vinh Chau,McLaws Mary-Louise 대한감염학회 2021 Infection and Chemotherapy Vol.53 No.3
Little is known about antibiotic-resistant Gram-negative bacteria (GNB) intestinal carriage among healthcare workers (HCWs) in Vietnam. All HCWs at a tertiary intensive care units were asked to undertake weekly rectal swabs. Among 40 participants, 65% (26/40) carried extended spectrum β-lactamases (ESBL)/AmpC β-lactamase-producing Escherichia coli. Two HCWs colonized with ESBL/AmpC β-lactamase-producing Klebsiella pneumoniae. One HCW colonized with Acinetobacter baumannii. No one carried Pseudomonas spp.. A quarter (10/40) of HCWs were identified as persistent and frequent carriers. There is an urgent need to screen antibiotic-resistant GNB among HCWs and improve HCWs’ hand hygiene compliance to reduce the transmission of antibiotic-resistant GNB in the hospital.
Taxus wallichiana Zucc. 현탁세포에서 Jasmonic Acid-Cellulase 복합 Elicitor가 Paclitaxel 생합성에 미치는 영향
Nguyen Ngoc Hoi,Hoang Van Luong,Nguyen Van Long,Vu Binh Duong,변상요(Sang Yo Byun) 한국생물공학회 2010 KSBB Journal Vol.25 No.2
Taxus wallichiana Zucc. 현탁세포배양에서 항암제 paclitaxel 생합성 연구를 수행하였다. 현탁세포배양에서 exponential phase의 최고 생장 속도는 0.14 day-1이었으며 배가시간이 4.96 day이었다. Paclitaxel은 배양초기에 생성되지 않고 exponential phase 말기부터 서서히 생성되어 stationary phase에서도 이어지며 declined phase에서 최고치를 나타내었다. Paclitaxel의 생산을 촉진하기 위하여 elicitor를 사용하였다. 여러 elicitor 중 jasmonic acid와 cellulase가 paclitaxel의 생성을 증가시켰다. Elicitor는 접종과 동시에 투여했을 때 가장 효과가 좋았으며, jasmonic acid와 cellulase의 combination으로 효과가 더욱 증진했는데 각각 투여할 때보다 1.8배 및 3.1배 paclitaxel 생성이 증가되었다. Cell cultures of Taxus wallichiana Zucc. were made to enhance the production of anticancer agent paclitaxel. In suspension cultures, the maximum cell growth rate in exponential growth phase was 0.14 day-1 which was correlated to 4.96 days of cell doubling time. The production of paclitaxel was non-growth associated. The paclitaxel production was started after the exponential growth phase and increased to declined phase where the maximum concentration was observed. Various elicitors were tested to enhance the production of paclitaxel. The combination of two elicitors of jasmonic acid and cellulase increased the production of paclitaxel 1.8 and 3.1 times compared to paclitaxel production by individual elicitor respectively.
Thermoelectric Properties of Hot-Pressed Bi-Doped n-Type Polycrystalline SnSe
Nguyen, Van Quang,Nguyen, Thi Huong,Duong, Van Thiet,Lee, Ji Eun,Park, Su-Dong,Song, Jae Yong,Park, Hyun-Min,Duong, Anh Tuan,Cho, Sunglae Springer US 2018 NANOSCALE RESEARCH LETTERS Vol.13 No.1
<P><B>ᅟ</B></P><P>We report on the successful preparation of Bi-doped n-type polycrystalline SnSe by hot-press method. We observed anisotropic transport properties due to the (h00) preferred orientation of grains along the pressing direction. The electrical conductivity perpendicular to the pressing direction is higher than that parallel to the pressing direction, 12.85 and 6.46 S cm<SUP>−1</SUP> at 773 K for SnSe:Bi 8% sample, respectively, while thermal conductivity perpendicular to the pressing direction is higher than that parallel to the pressing direction, 0.81 and 0.60 W m<SUP>−1</SUP> K<SUP>−1</SUP> at 773 K for SnSe:Bi 8% sample, respectively. We observed a bipolar conducting mechanism in our samples leading to n- to p-type transition, whose transition temperature increases with Bi concentration. Our work addressed a possibility to dope polycrystalline SnSe by a hot-pressing process, which may be applied to module applications.</P><P><B>Highlights</B></P><P><P>We have successfully achieved Bi-doped n-type polycrystalline SnSe by the hot-press method.</P><P>We observed anisotropic transport properties due to the [h00] preferred orientation of grains along pressing direction.</P><P>We observed a bipolar conducting mechanism in our samples leading to n- to p-type transition.</P></P><P><B>Electronic supplementary material</B></P><P>The online version of this article (10.1186/s11671-018-2500-y) contains supplementary material, which is available to authorized users.</P>
Nguyen Huu-Manh,Duong The-Khang,Nguyen Van-Khuyen,Nguyen Thi-Khanh-Ly,Dong Thi-Hoang-Yen,Nguyen Canh-Hung,Tung Nguyen-Thach 한국약제학회 2024 Journal of Pharmaceutical Investigation Vol.54 No.2
Purpose A two-step experimental design was used to develop a lornoxicam (LOR)-loaded topical hydrogel patch. We specifically focused on the simultaneous effect of the ion pair formation agent (triethanolamine [TEA]) and the chemical enhancer (cremophor RH40 [RH40]) on flux and conducted physicochemical studies and skin physiology assessments to obtain further information. Methods Drug-in-adhesive patches were fabricated using a micrometer-adjustable film applicator. The applied Design of Experiments (DoE) approach consisted of the Fractional Factorial Resolution V + design and the Central Composite Face design established by the MODDE® 12.0 software. Molecular-level drug-excipient interactions were investigated using infrared (IR) and proton nuclear magnetic resonance (1H NMR) spectroscopy. The effects on skin physiological function was assessed using DermaLab Combo. Results DoE results revealed that TEA enhanced flux by 3.14-fold, whereas RH40 reduced it by 4.62-fold. The addition of RH40 resulted in the disappearance of the proton peak within the region of 12–13 ppm, suggesting competition for hydrogen bonding with LOR between TEA and RH40. The optimized formulation (4% TEA, 0% RH40, and 0.2% Al(OH)3) increased skin hydration by 6.20-fold. Opposing effects of TEA and RH40 on skin elasticity were observed. Conclusion Expected flux and adhesion strength for the optimized formulation were 7.18 μg·cm–2·h–1 and 11.79 mJ, respectively. Our understanding of the conflicting effects of TEA and RH40 has been advanced. The integrated use of the two-step DoE, physicochemical studies, and skin physiology assessments was proven to be effective in elucidating the simultaneous effects of different permeation-modifying strategies on patches, thus having substantial value for the successful execution of future research endeavors.
Nguyen, Tuan Lam,Pham, Thi Quynh Nga,Hoang, Van Minh,Kim, Bao Giang,Phan, Thi Hai,Doan, Thu Huyen,Nguyen, Thuy Linh,Duong, Khanh Van,Luong, Ngoc Khue Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.no.sup1
Second-hand tobacco smoke (SHS) exposure at home, especially among children, is a serious issue in Viet Nam. During the past decade, much effort has been taken for tobacco control in the country, including various prgorammes aiming to reduce SHS exposure among adults and children. This article analysed trends and factors associated with SHS exposure at home among school children aged 13-15 in Viet Nam, using the Global Youth Tobacco Surveys conducted in 2007 and 2014. Descriptive and inferential statistical methods with logistic regression were applied. Overall, there was a significant reduction in the level of exposure, from 58.5% (95%CI: 57.6-59.3) in 2007 to 47.1% (95%CI: 45.4-48.8) in 2014. Of the associated factors, having one or both parents smoking was significantly associated with the highest odds of SHS exposure at home (OR=5.0; 95%CI: 4.2-6.1). Conversely, having a mother with a college or higher education level was found to be a protective factor (OR=0.5; 95%CI: 0.3-0.8).
Duong Van Thiet,NGUYENVAN QUANG,Nguyen Thi Minh Hai,Nguyen Thi Huong,조성래,Duong Anh Tuan,Dang Duc Dung,트란반탐 한국물리학회 2018 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.72 No.8
In this work, we report on the structural and thermoelectric properties of Sb2Te3 films deposited on GaSb(111) substrates by using molecular beam epitaxy. The effects of the growth temperature on the microstructure and thermoelectric properties of the films were investigated. The results show that Sb2Te3 films grow on GaSb(111) along (00l) axis normal to the substrate and have a hexagonal structure with a layer-by-layer growth mode in growth temperature range from 200 to 250 °C while at 175 and 300 °C, the films show an island growth mode. Te and Sb2Te3 phases coexist at a growth temperature of 175 °C. The films exhibit a metallic behavior for growth temperatures below 250 °C and a semiconductor behavior at 300 °C. By changing growth temperature, we were able to vary the carrier density from 9.96×1018 to 4.55×1019 cm −3. At room temperature, the Seebeck coefficients are 110, 146, and 138 μV/K for growth temperatures of 175, 200 and 250 °C, respectively, and a large value of the power factor 61.67 μW/cm-K2 is achieved for the film grown at 250 °C.
Spectral and Energy Efficiencies in Full-Duplex Wireless Information and Power Transfer
Nguyen, Van-Dinh,Duong, Trung Q.,Tuan, Hoang Duong,Shin, Oh-Soon,Poor, H. Vincent Institute of Electrical and Electronics Engineers 2017 IEEE Transactions on Communications Vol. No.
<P>A communication system is considered consisting of a full-duplex multiple-antenna base station (BS) and multiple single-antenna downlink users (DLUs) and single-antenna uplink users (ULUs), where the latter need to harvest energy for transmitting information to the BS. The communication is thus divided into two phases. In the first phase, the BS uses all available antennas for conveying information to DLUs and wireless energy to ULUs via information and energy beamforming, respectively. In the second phase, ULUs send their independent information to the BS using their harvested energy while the BS transmits the information to the DLUs. In both the phases, the communication is operated at the same time and over the same frequency band. The aim is to maximize the sum rate and energy efficiency under ULU achievable information throughput constraints by jointly optimizing beamforming and time allocation. The utility functions of interest are nonconcave and the involved constraints are nonconvex, so these problems are computationally troublesome. To address them, path-following algorithms are proposed to arrive at least at local optima. The proposed algorithms iteratively improve the objectives with convergence guaranteed. Simulation results demonstrate that they achieve rapid convergence and outperform conventional solutions.</P>