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Improvement of properties of self-flowing low-cement castables based on brownfused alumina
Necip Ünlü,Cem Gögtas,Akln Odabasl,Levent Sezer,Filiz Çlnar,Sule Güner,Niyazi Eruslu 한양대학교 세라믹연구소 2007 Journal of Ceramic Processing Research Vol.8 No.5
A new self flowing brown-fused alumina based castable with 5 wt.% cement has been developed. An Andreason mathematical model (q=0.25) was used to adjust the granulometric particle size distribution. To achieve optimum self-leveling flowability, 5.6% water was used. The main physical and mechanical properties of the present castable were studied. Phase analysis using X-ray diffraction (XRD), scanning electron microscopy (SEM) and apparent porosity (AP), bulk density (BD), water absorption (WA), cold crushing strength (CCS), hardness, and self-leveling flowability were investigated as a function of the firing temperature. The castable exhibited low AP and WA, and high CCS values with an increase in the firing temperature as a result of the corresponding phases. A new self flowing brown-fused alumina based castable with 5 wt.% cement has been developed. An Andreason mathematical model (q=0.25) was used to adjust the granulometric particle size distribution. To achieve optimum self-leveling flowability, 5.6% water was used. The main physical and mechanical properties of the present castable were studied. Phase analysis using X-ray diffraction (XRD), scanning electron microscopy (SEM) and apparent porosity (AP), bulk density (BD), water absorption (WA), cold crushing strength (CCS), hardness, and self-leveling flowability were investigated as a function of the firing temperature. The castable exhibited low AP and WA, and high CCS values with an increase in the firing temperature as a result of the corresponding phases.
Levels of Serum Trace Elements in Renal Cell Carcinoma Cases
Pirincci, Necip,Gecit, Ilhan,Gunes, Mustafa,Kaba, Mehmet,Tanik, Serhat,Yuksel, Mehmet Bilgehan,Arslan, Harun,Demir, Halit Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.1
Trace elements which are essential components of biological structures may also be toxic when present at levels above the amounts required for biological function. In our study, trace element levels were measured with furnace atomic absorption spectrophotometry in 33 newly diagnosed renal cell carcinoma cases (preoperative) and 32 healthy controls. When compared with the control group, it was found that the levels of cadmium (Cd), lead (Pb) were higher and the levels of zinc (Zn), iron (Fe) and manganese (Mn) were lower in the patient group. These changes may be important in the formation of renal cell carcinoma, a question which should be explored with postoperative comparative studies.
Pirincci, Necip,Gecit, Ilhan,Gunes, Mustafa,Kemik, Ahu Sarbay,Yusel, Mehmet Bilgehan,Kaba, Mehmet,Ceylan, Kadir,Aslan, Mehmet Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.12
Although alteration in the haptoglobin phenotype has been reported in patients with bladder cancer, serum haptoglobin levels have not been evaluated. We hypothesized that serum haptoglobin can be used as a biomarker. The aim of this study was to evaluate the expression of haptoglobin in bladder cancer and to determine the relationship with clinicopathological features. A total of 68 serum specimens obtained before surgery were used to investigate haptoglobin expression using the sandwich ELISA technique. Serum haptoglobin levels were higher in the patients with bladder cancer compared to healthy controls (p<0.0001). Additionally, the levels of haptoglobin protein increased with increasing tumor grades (p<0.001) and were significantly higher in patients with metastatic disease and the presence of lymphovascular involvement, lymph node metastases and increasing tumor burden (p<0.0001). This study suggests that elevated haptoglobin levels are associated with a higher stage, grade, and extent of distant metastasis and larger tumor size. Haptoglobin may therefore provide a useful diagnostic and treatment biomarker for patients with bladder cancer.
Asim Olgun,Necip Atar 한국공업화학회 2012 Journal of Industrial and Engineering Chemistry Vol.18 No.5
The present study examined the use of waste containing boron impurity (BC) from boron enrichment plant for the removal of lead (II) and nickel (II) from aqueous solutions. The effects of pH, contact time,initial dye concentration, adsorbent dosage, and temperature on the adsorption process were examined. Residual lead and nickel concentration reached in equilibrium in 90 min and the rate of adsorption by BC was rapid in the first 45 min of the reaction time. The pseudo- second-order kinetic model best described the kinetic of the adsorption. Batch adsorption studies showed that the adsorption patterns followed Langmuir isotherm model.
Kaba, Mehmet,Pirincci, Necip,Benli, Erdal,Gecit, Ilhan,Gunes, Mustafa,Yuksel, Mehmet Bilgehan,Tok, Adem,Kemik, Ahu Sarbay Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1
Background: Evidence indicates that Dickkopf-1 (DKK-1) levels may be a biomarker for cancer risk. The aim of this study was to assess DKK-1 and its correlation with clinic-pathological features in patients with bladder cancer. Materials and Methods: DKK-1 levels were determined in serum samples from 90 patients with bladder cancer before transurethral tumor resection. The concentrations of DKK-1 were determined by using enzyme linked immune-sorbent assay (ELISA). Results: Elevated preoperative DKK-1 levels were associated with tumor stage (p<0.001), grade (p<0.001) and histological grade (p<0.001). Conclusions: The results of our study demonstrated that the level of serum DKK-1 is correlated with both disease progression and increase in the tumor grade. Preoperative serum DKK-1 elevation may thus represent a novel marker for the determination of bladder cancer and the detection of patients with a likely poor clinical outcome.
Nature of Lesions Undergoing Radical Nephrectomy for Renal Cancer
Mustafa, Gunes,Ilhan, Gecit,Necip, Pirincci,Kerem, Taken,Kadir, Ceylan Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9
Aim: The aim of the present study was to evaluate retrospectively histopathologically-diagnosed lesions that were detected in the kidney after radical nephrectomy for a preoperative diagnosis of kidney cancer. Methods: The medical records of 83 patients (51 male, 32 female) were included. Preoperative staging was accomplished by various methods including physical examination, blood hemography and biochemistry, abdominal ultrasonography (US), chest x-ray, abdominal computed tomography (CT) and abdominal magnetic resonance imaging (MRI). Results: Totals of 70 patients underwent radical nephrectomy and 13 nephron sparing surgery. Of the 83 patients, 70 had malignant lesions (renal cell carcinoma, squamous cell carcinoma or other malignancies) 13 had a variety of benign lesions, the most frequently detected being oncoytoma (6), angiomyolipoma (3), xanthogranulamatous pyelonephritis (2), cortical cyst (1) and chronic pyelonephritic change (1). Conclusion: It was concluded that in spite of great technological developments regarding radiological imaging modalities such as US, CT and MRI, benign lesions might still be detected pathologically in patients who undergo radical nephrectomy with the preoperative diagnosis of renal cancer. But, all renal masses should be regarded as malignant and should be managed surgically otherwise proven benign.
Ferdag Colak,Asim Olgun,Necip Atar,Demet Yazıcıoglu 한국공업화학회 2013 Journal of Industrial and Engineering Chemistry Vol.19 No.3
Continuous fixed-bed column and batch biosorption studies were conducted to examine the effectiveness of Paenibacillus polymyxa as an adsorbent for the removal of copper and nickel from aqueous solutions. Experimental data obtained has been fitted well with Langmuir isotherm model and also exhibited very high correlation coefficients which confirmed suitability of the model and biosorption process. Differences among batch and continuous isotherms were observed; the maximum uptake capacity of Cu(II) and Ni(II) in batch system was about 49.8 (mg/g) and 35.02 (mg/g), respectively. Furthermore, the effects of heavy metals on micro-organism growth were studied.
Serum Levels of Trace Elements in Patients with Prostate Cancer
Kaba, Mehmet,Pirincci, Necip,Yuksel, Mehmet Bilgehan,Gecit, Ilhan,Gunes, Mustafa,Ozveren, Huseyin,Eren, Huseyin,Demir, Halit Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.6
Background: Trace elements are major components of biological structures; however, excessive levels of these elements can be toxic. Materials and Methods: In the present study, serum levels of trace elements were measured in 30 patients with newly diagnosed as prostate cancer and 32 healthy volunteer by using furnace atomic absorption spectrophotometry. Results: It was found that there was an increase in serum levels of Co, Cu, Mg and Pb (p<0.05), whereas a decrease in serum levels of Fe, Mn, and Zn levels in patients with prostate cancer (p<0.05). Conclusions: These changes may be important in the pathogenesis of prostate cancers; however, further prospective studies are needed to identify relationships between prostate cancer and trace elements.
Gunes, Mustafa,Kemik, Ahu Serap,Pirincci, Necip,Gecit, Ilhan,Taken, Kerem,Yuksel, Mehmet Bilgehan,Kaba, Mehmet,Eryilmaz, Recep Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.2
Our aim was to test the hypothesis that preoperative serum levels of matrix metalloproteinase-7 (MMP-7) and -9 (MMP-9) and tissue inhibitor of matrix metalloproteinase (TIMP-1) levels correlate with pathological features. Serum levels of MMP-7, and MMP-9 and TIMP-1 were determined in 90 bladder cancer patients and 40 healthy controls using an enzyme linked immunosorbent assay. Preoperative serum MMP-7 and MMP-9 levels were significantly higher in cancer patients than control groups (p<0.001). In contast, serum TIMP-1 levels were lower (p<0.001). Alteration in MMP-7, and MMP-9, and TIMP-1 production may contribute to tumor angiogenesis and be associated with clinic-pathological features.
Is Diabetes Mellitus a Prognostic Factor for Survival in Patients with Small Cell Lung Cancer?
Inal, Ali,Kaplan, M. Ali,Kucukoner, Mehmet,Urakci, Zuhat,Karakus, Abdullah,Nas, Necip,Guven, Mehmet,Isikdogan, Abdurrahman Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.4
Background: Previous studies have pointed to many different prognostic factors for small cell lung cancer (SCLC) but diabetes mellitus (DM) has not been clearly or consistently identified as of prognostic value. The aim of this study was to investigate the prognostic significance of the characteristics of patients and clinical laboratory tests in SCLC. Specifically, we investigated that the impact of DM for survival in the patients receiving first-line etoposide plus cisplatin (EP) chemotherapy. Methods: We retrospectively reviewed 161 patients with SCLC with a focus on DM and other potential prognostic variables were chosen for univariate and multivariate analyses with respect to survival. Result: Among the sixteen variables of univariate analysis, five were identified to have prognostic significance: performance status (PS) (p<0.001), stage (p=0.001), DM (p=0.005), serum albumin (p<0.001) and hemoglobin levels (p=0.03). Multivariate analysis showed PS, stage and serum albumin level to be independent prognostic factors for survival (p=0.02, p=0.02 and p=0.009 respectively), but DM was not an independnet factor. Conclusion: In conclusion, PS, stage and serum albumin level were identified as important prognostic factors, while DM at the time of diagnosis of SCLC did not have prognostic importance for survival.