돌발성 난청의 임상적 분석

남부현,강갑진,성열웅,송영복 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Sudden hearing loss is an abrupt onset of sensorineural hearing loss over a period of hours or a few days without definite cause. The cause and its pathophysiology have not been fully determined, and the treatmnet is controversial at present. The purpose of this study is to seek the best modality of treatment by clinical and stastical analysis of 48 patients (28 male and 20 female) diagnosed as a sudden hearing loss from January 1993 to October 1995. The therapeutic results of the 48 patients were 20 cases (41.7%) of complete recovery, 3 cases (6.2%) of partial recovery, 4 cases (8.3%) of slight recovery and 21 cases (43.8%) of no improvement. Early treatment within a week of onset, ascending or flat types of audiogram, and normal ABR were favorable prognostic factors in recovery of hearing. The presence of accompanying vestibular symptom (ie, vertigo) and profound hearing loss on initial audiogram were poor prognostic factors. However, the gender and the age of the patients did not affect on the hearing result.

체외형 자동 제세동기(AED)와 심전도계(ECG)를 위한 통신 프로토콜의 설계 및 사용자 인터페이스 구현

김남훈,권희중,권호열,나학록 江原大學校 産業技術硏究所 2004 産業技術硏究 Vol.24 No.A

In this paper, we studied Automated External Defibrillator and Electro- Cardiogram System. Proposed System, CU-EX1, is a PC-based AED/ECG system that manages the data acquired by Paramedic CU-ER1. The system controls the transfer of data from the Paramedic CU-ER1 and the storage of the data in a local host computer. Patient data could be entered as soon as the rescue data is stored in a local computer. The system also displays the data on a local computer and facilitates review of rescue events.

알러지성 비염 환자 107례에 대한 神鼻煎의 임상적 효과

김경렬,장현호,두인선,김남권,이종화,유영수,강형원 한국전통의학연구소 2002 한국전통의학지 Vol.12 No.1

Allergic rhinitis is characterized by rhinorrhea, sneezing and nasal obstruction. Allergic rhinitis increases because of developments of diagnostic techniqhe, environmental change, especially industrialization. Recently people have studied on allergic rhinitis. We studied 107 allergic rhinitis patients with SBJ from June. 2002 to December, 2002. There was a significant effect of SBJ on allergic rhinitis. So, we suggested the clinical effect of SBJ on allergic rhinitis.

新開墾地이 大豆에 대한 溶成燐肥 增施에 따른 加里施用의 效果

金鎭淇,黃南悅 全北大學校 1983 論文集 Vol.25 No.-

野山新開墾地土壤松汀統에서 光敎를 供時하여 溶成燐肥增施에 따른 加里增施效果에 關한 試驗結果를 要約하면 다음과 같다. 1. 收量에서 燐酸吸收係數 5% 調節施用區에서는 C.E.C. 5%의 加里施用區에서 最高收量 252㎏/10a, 燐酸吸收係數 10% 調節施用區에서는 C.E.C. 10%의 加里施用區에서 最高收量 282㎏/10a을 각각 얻었다. 2. 加里施用量과 收量間의 相關에서는 燐酸 48㎏/10a 施用時 加里 19㎏/10a 水準에서 最高收量을 얻을 수 있는 相關을 보였다. 3. 溶成燐肥增加와 함께 加里를 增施할 때 收量이 계속 增大되지 않았으며 이는 溶燐中의 Ca와 Mg의 增施와 더불어 加里가 多量施用됨으로써 鹽類가 蓄積되어 生理的障碍에 依한 것으로 思料된다. 4. 最高收量을 얻을 수 있는 加里活性度 (K/ √Ca+Mg)는 0.144로써 統計的인 有意性이 認定되었다. This experiment was carried out to study the effect of potassium application with fused phosphate to newly reclaimed soil (Song jeong Series) on soybean. The results are summarized as follows. 1. 5% phosphate absorption coefficient(P.A.C) with 5% cation exchange capacity(C.E.C) and 10% P.A.C. with 10% C.E.C. showed maximum yields being 10% and 19% increase in yield than non-treatment respectively. 2. Application of 19㎏/10a potassium with 48㎏/10a phosphate and 25㎏/10a potassium with 101㎏/10a phosphate could show highest soybean yields on newly reclaimed soil through regression equation of phosphate and potassium. 3. Increased fused phosphate and potassium applied to the reclaimed soil were not followed with increased yield in parallel presumably on account of salt injury of fused phosphate and potash. 4. Between yield and potassium were high correlation and the maximum yield coincided with 0.144 potassium activity degree(K/ √Ca+Mg).

Bacillus sp. Ye-1213이 생산하는 chitinase의 동정, 분리정제 및 특성

오두환,허남윤,백무열 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.1

국내 해변 연안의 해변의 토양으로부터 chitinase 활성이 우수한 균주를 분리하고 동정하여 Bacillus sp. YE-1213으로 명명하였다. Chitinase를 생산하기 위한 최적 배양조건은 1.0%(w/v, dry base) Colloidal chitin, 1.0%(w/v) Tryptone, 0.05%(w/v) MgSo₄·7H₂O, pH 8.0, 30℃, 배양시간 48시간이었다. 효소는 (NH₄)₂SO₄분별침전, affinity adsorption, Sephadex G-200 gel filtration의 과정을 거쳐 정제한 결과 비활성 81.32units/mg, 정제도 16.7배, 수율은 15.8%이었다. 정제된 효소는 최적 반응조건은 pH 6.0, 40℃ 이었으며, 온도에 대한 효소안전성은 40℃까지는 매우 안정하였고 pH에 대한 안정성은 pH 5.0-9.0에서 안정하였다. 정제된 효소의 Km 값은 1.74mg/ml이었고 PCMB, I₂, ?? ion, ?? ion 에 의해 저해되었으며 ?? ion, ?? ion 및 ?? ion 에 의해 1.21배, 1.12배, 1.18배의 효소활성이 증가하였다. A bacterium with the highest chitinase activity selected from the soil and identified as a Bacillus sp. YE-1213. The optimal condition for the production of chitinase was as follows; 1.0% (w/v, dry base) colloidal chitin, 1.0%(w/v) tryptone, 0.05%(w/v) MgSO₄·7H₂O, pH8.0, 30℃, 48 hrs. The chitinase was purified about 16.7 folds by ammonium sulfate fraction, affinity adsorption and Sephadex G-200 gel filtration. Optimal temperature and pH for the enzyme activity were 40℃ and pH 6.0. The enzyme was stable between pH 5.0-9.0 and up to 40℃. Its activity was activated by ??, ??, and ?? while inhibited by PCMB, I₂, ?? and ??.

효소처리 찹쌀 전분의 이화학적 성질 및 유과제조 특성

유철,김종태,허남윤,김동섭,백무열 경희대학교식량자원개발연구소 2007 硏究論文集 Vol.26 No.1

유과 제조 시 제조 시간을 단축할 수 있는 소재를 개발하기 위하여 찹쌀 전분을 4가지 상업용 α-amylase 효소와 반응시켜 효소처리 찹쌀 전분을 제조하고 이들의 이화학적 특성을 연구하였다. 효소처리 찹쌀 전분의 팽윤력 및 용해도는 일반 찹쌀 전분에 비해 많이 증가되는 경향을 보였다. 등온흡습곡선에서는 효소처리에 따른 유의적인 차이는 나타나지 않았다. RVA특성을 검토한 결과 최대 점도, holding strength, final viscosity, break down, setback은 일반 찹쌀 전분보다 낮아지는 결과를 나타냈다. 열적특성에서는 아밀로펙틴 용해 개시온도, 아밀로펙틴 용해 종결온도 그리고 아밀로펙틴 용해 온도범위(△T)는 각 전분간에 유의적인 차이가 나타나지 않았으며 아밀로펙틴 용해 엔탈피 역시 유의적인 차이를 나타내지 않았다. X-ray 회절 분석 결과로 볼 때, 효소처리 찹쌀 전분 및 일반 찹쌀 전분 모두 A형의 결정 형태를 나타내었고, 상대적 결정화도의 차이가 나타나지 않는 것으로 보아 효소처리가 찹쌀 전분의 결정형영역에는 영향을 주지 않는 것으로 보여진다. 효소처리 찹쌀 전분을 사용하여 제조한 유과의 경우 과도한 점도손실에 의해 반죽을 제조하지 못하여 본 연구에서 사용한 효소치리 정도가 부적합한 것으로 판단되었다. Physicochemical properties of partially hydrolyzed waxy rice starches with various α-amylases were investigated to reduce processing-time of yukwa (Korean traditional puffed rice snack). Four commercial α-amylases (Fungamyl, Termamyl, Liquozyme, Kleis tase) were used in this work. Waxy rice starches (20% solid content) were treated with same unit of four α-amylases at 40℃ and pH 6.0 for 1 hour. Partially hydrolyzed waxy rice starches showed higher swelling power and solubility than native waxy rice starch. Pasting temperature and peak viscosity of partially hydrolyzed waxy rice starches were lower than those of native starch. DSC thermal transitions of partially hydrolyzed waxy rice starches shifted to higher temperature than native waxy rice starch possibly due to hydrolysis of amorphous region and some double helical structure. X-ray diffraction patterns of both native and partially hydrolyzed waxy rice starches were typical A-type pattern indicating that alpha-amylase cannot disrupt the crystalline structure in this condition.

백서 척수후근절로부터 슈반세포의 효과적인 체외 배양법

김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.

벼 기계이앙 1회용 종이 육묘상자 개발

박성태,황정동,김상열,문헌팔,양세준,김순철,유남진 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.3

벼 기계이앙 육묘에 주로 사용하고 있는 플라스틱 육묘상자의 문제점을 개선하고 친환경 농업 실현에도 기여할 수 있는 벼 기계이양 종이 육묘상자개발 및 육묘시험 결과를 요약하면 다음과 같다. 1. 폐지 등 혼합물을 고열압착한 종이 육묘상자는 내부 길이가 가로 58㎝, 세로 28㎝, 높이는 2㎝이고 무게는 250g이다. 2. 종이 육묘상자 모의 파종 후 10일~30일 묘소질은 플라스틱 육묘상자 모에 비하여 초장이 1.1~1.8㎝ 짧고 본당 건물중은 0.3~3.7㎎이 떨어졌으나 엽수와 모 충실도는 비슷하였다. 3. 종이 육묘상자 모의 파종 후 30일(중묘) 이앙 시 결주율은 3.3%로 플라스틱 육묘상자 모 결주율 3.2%와 거의 같았고, 출수기, 벼 생육특성 및 수량도 플라스틱 육묘상자와 비슷하였다. 4. 종이 육묘상자의 이점은 플라스틱 육묘상자에 비하여 육묘상자 비용이 약 20% 절감되고 파종 후 운반, 치상 등 작업이 용이하며, 이앙 후 회수, 세척 및 보관관리 노력이 생략된다. 그리고 이앙 후는 논에서 유기물화되므로 친환경농업에도 부합된다. A light and bio-degradable paper tray for seedling raising in machine transplanting rice was developed for the first time and a possibility for rice seedling growth was evaluated. The paper tray was made of mixture of recycling paper and sawdust, and molded under high temperature and pressure. The tray was 58㎝ length x28㎝ width x2㎝ height in size and 250g in weight per tray. The seedling height and dry weight per plant grown at the paper tray were generally 1.1 to 1.8㎝ shorter and 0.3 to 3.7㎎ lighter than those grown at the conventional plastic tray, respectively. However, other characters such as leaf number, seedling health score, missing hill, heading date, panicle and spiketlet number, and milled rice yield were similar to those in the plastic tray. Based on the result of research, the paper tray had following advantages in comparison of the plastic tray. The paper tray could be reduced seedling raising cost by 20% as compared with the plastic tray. Since the paper tray was of lightness even after seedbed soil fill-up, it was more handy and convenient to carry over. Labor input for collecting, washing, and storing the empty tray after seedling transplanting was not needed as the plastic tray. The paper tray was also bio-degraded and transformed into an organic matter, once it was incorporated into soil, which was considered as an environmentally- safe cultivation technology.

상지 단순반복작업 근로자의 수근관 증후군 유병률에 관한 조사

손지언,장태원,김윤규,홍영습,정갑열,김동일,이강진,하남진,김상범,김준연 대한산업의학회 2001 대한직업환경의학회지 Vol.13 No.3

목적 : 본 연구는 수근관 증후군의 발생위험이 높은 작업형태에 종사하는 상지 단순반복작업근로자로서 육류 및 어류 가공 사업장과 목재소 근로자에서 근전도검사를 이용하여 수근관 증후군의 유병률을 조사하고자 하였다. 방법 : 상지 단순반복작업근로자로서 육류 및 어류 가공 사업장 근로자 69명과 목재소 근로자 17명을 실험군으로, 관리직, 경리, 경비등 상지의 단순반복작업이 없는 근로자 28명을 대조군으로 선정하여, 작업적 및 병력조사, 이학적 검사와 근전도검사를 통해 수근관 증후군의 유병률을 조사하였다. 결과 : 수근관 증후군의 유병률은 육류 및 어류 가공 사업장과 목재소에서 각각 26.09 % (18명)와 29.41 %(5명)로 조사되었으며, 육류 및 어류가공사업장과 목재소 근로자를 '7년 이상과 미만의 작업기간'으로 층화하여 비교한 결과 '상지부위의 통증 호소 유무', 'Visual Analogue Scale(VAS: 총 10점) 4점 이상 여부', 'Tinel teat 양성 유무', 'Phalen test 양성 유무'는 모두 단기 작업근로자군에서 양성의 빈도가 증가되었고 '수근관 증후군 유무'는 장기작업근로자군에서 양성의 빈도가 증가되었다. 결론 : 육류 및 어류 가공 사업장과 목재소의 수근관 증후군 유병률은 각각 26.09 %와 29.41 %로 육류 및 어류 가공 사업장과 목재소는 1996년 OSHA가 지정한 바와 같이 위험한 작업요인이 있는 작업장으로 분류하여 관리되어야 할 것으로 생각된다. Objectives : This study was carried out to survey on the prevalence of Carpal Tunnel Syndrome(CTS) in high risk jobs(meat and fish processing plant and wood plant), by application of Nerve Conduction Study(NCS), a confirmatory diagnostic method. Methods : Experimental group was 69 workers sampled from meat and fish processing plants and 17 workers sampled from wood plants, who were simple, repetitive workers using upper extremities and control group was 28 workers sampled from managers, secretaries and keepers. All employees were examined through work history, physical examination and NCS. Results : 18 workers(26.09%) in meat and fish processing plants, and 5 workers(29.41%) in wood plants had compatible findings to NIOSH diagnostic criteria for CTS. The experimental group had more symptoms (complaint of upper extremities, Visual Analogue Scale ≥4(VAS: total 10 point)), signs(Tinel and Phalen test) and prevalence of CTS than control group(p<0.05). The prevalence of symptoms and signs were higher in short term workers(<7 years), but the prevalence of CTS was higher in long term workers(≥7 years). Conclusions : The prevalence of CTS in meat and fish processing plant and wood plant were 26.09% and 29.41% respectively. Authors propose that meat and fish processing and wood plants should be managed as a risk job category which were designated by OSHA in 1996

^(131)I 전신스캔 음성 재발 분화 갑상선암에서 EDG PET의 임상적 의의 : ^(99m)Tc-MIBi Scintigraphy와 비교분석

원종철,이성진,이태윤,남궁일성,이시열,김하영,한정희,류진숙,문대혁,안일민 대한내분비학회 2001 Endocrinology and metabolism Vol.16 No.4-5