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Synthesis and antimickrobial activity of benzofuran-carboxamide derivatives
Hishmat, O.H.,Nasef, A.M.,El-Naem, Sh.I.A.,Shalaby, A.M. The Pharmaceutical Society of Korea 1989 Archives of Pharmacal Research Vol.12 No.4
The reaction of the sodium salts of 4-methoxy and 4, 7-dimethoxy 6-hydroxy benzofuran-5-carboxylic acid with ethyl chloroformate yields the corresponding dicarbethoxy derivatives. The N-substituted amides were obtained by treating the latter compounds with amines. The corresponding hydrazides were synthesized by the reaction of hydrazine hydrate on the dicarbethoxy derivatives which spontaneously cyclized to 5-substituted-2, 3- dihydro-1, 3, 4, -oxadiazol-2-one. Also the reaction with phenyl hydrazine has been studied. The dicarbethoxy derivatives and N-substituted amides were tested against Gram positive and Gram negative bacteria in vitro. Most of the compounds posses moderate or slight activity against Gram positive bacteria.
이종규 ( Jong Kyu Lee ),장지휘 ( Ji Hwi Jang ),이양 ( Li Yang ),김해냄 ( Hae Naem Kim ),곽명자 ( Myeong Ja Kwak ),( Inkyin Khaine ),이태윤 ( Tae Yoon Lee ),이현경 ( Hyun Kyung Lee ),김이레 ( Ie Rae Kim ),장경환 ( Gyeong Hwan J 한국임학회 2017 한국산림과학회지 Vol.106 No.2
본 연구에서 일반 토양에 비해 무기양분 함량이 적고 배수성이 좋지 않은 새만금간척지 토양에 식재 된 포플러수종의 생리적 특성을 조사하였다. 7월과 8월에, 이태리포플러 클론인 Venziano, L.Avanzo와 미루나무 교잡종 클론인97-18, 97-19은 생리적인 특성의 차이를 보였다. 이태리포플러 클론이 미루나무 교잡종 클론에 비해 생리적 특성이 우수하였다. 특히 Venziano 클론의 순광합성률은 각각 평균적으로 18.62 μmol CO<sub>2</sub> m<sup>-2</sup> · s<sup>-1</sup>, 17.11μmol CO<sub>2</sub> m<sup>-2</sup> · s<sup>-1</sup>로 다른 클론들과 비교해서 높은 수치를 보였다. 반면, 미루나무 교잡종인 97-18클론의 7월 광색소 함량은 2.37 mg · g<sup>-1</sup>FW으로 가장 높은 수치를 보였으나, 8월에는 이태리포플러 클론보다 낮은 함량을 보였다. 미루나무 교잡종은 8월에 순광합성률, 광색소함량 등 전반적인 생리적 활성이 떨어졌다. 결론적으로, 새만금간척지에 식재된 포플러 묘목의 생리적인 특성은 이태리포플러 종인 Venziano 클론이 우수하였다. This research aims to study the physiological characteristics of poplar clones in Saemanguem reclaimed land where has lower minerals and bad drainage than those in paddy field. In July and August, different poplar clones including Populus euramericana clone (Venziano and L.Avanzo) and deltoides hybrid clone (97-18 and 97-19) showed different physiological characteristics. Physiological characteristics of P. euramericana clones were better than those of P. deltoides hybrid clones. Especially, the average net photosynthetic rate (A<sub>net</sub>) of clone Venziano were 18.62 μmol CO<sub>2</sub> m<sup>-2</sup> · s<sup>-1</sup> and 17.11μmol CO<sub>2</sub> m<sup>-2</sup> · s<sup>-1</sup>, respectively. Those were the highest numerical values among other poplar clones. On the other, the total chlorophyll and carotenoid contents of P. deltoides hybrid clones were higher than those of P. euramericana clones in July. Particularly, the total chlorophyll content of clone 97-18 was 2.37 mg · g<sup>-1</sup>FW. In August, those of P. deltoides hybrid clones decreased than in July. In term of the physiological activity such as net photosynthetic rate and stomatal conductance of P. deltoides hybrid clones were much lower in August than in July. As a result, physiological characteristics of P. euramericana Venziano clone was superior than the other clones in Short rotation coppice (SRC) in Saemanguem area.