http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Enhancement of Radioprotection and Anti-Tumor Immunity by Yeast-Derived β-Glucan in Mice
Yoshimi Niwano,Yasuyuki Takagi,Takashi Nakamura,Takeo Hasegawa,Ikukatsu Suzuki,Masami Oshima,Hitoshi Tawaraya,Yeun-hwa Gu 한국식품영양과학회 2005 Journal of medicinal food Vol.8 No.2
Intraperitoneal injection of .-glucan was shown to greatly delay mortality in mice exposed to whole-bodyX-ray radiation and tumor growth in tumor-bearing mice. Since the leukocyte and lymphocyte numbers were increased by asingle dose of .-glucan, the radioprotective effect of .-glucan is probably mediated, at least in part, by a hemopoietic actionin irradiated mice. In addition, both natural killer (NK) and lymphokine-activated killer (LAK) activities were significantlyincreased by repeated doses of .-glucan. Augmented immunological activity as seen in increased NK and LAK activity by .-glucan seems to play a role in preventing secondary infections associated with irradiation, and probably contributes to theattenuated tumor growth in tumor-bearing mice through enhanced anti-tumor immunity. These results suggest that .-glucanmay be a promising adjunct treatment for cancer patients receiving radiotherapy.