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서광수,이명석 공주대학교 문화재보존과학연구소 2003 문화재과학기술 Vol.2 No.1
천안시 백석동 3공단의 유적지에서 화분포자화석 연구를 위하여 8개의 시료를 채취하였다. 8개의 시료(試料)중 1개의 시료 (시료 3146)만이 소나무속(Pinus)이 압도적으로 산출되는 현재와 유사한 식생을 나타낸다. 전반적으로 균류(fungi; 菌類)의 산출이 많고 돌기체(突起體)를 갖는 2세포 균류 포자(胞子)가 특징적으로 산출된다. 또한 Gentianaceae/Euphorbiaceae 와 연관된 종류로 생각되는 다양한 형태의 화분이 국부적(局部的)인 식생을 반영해서 전체 시료 중 상당량 관찰된다. Eight samples for analysis of spore and pollen are collected from the archeological site in Baegsuchdong of Chunan. Korea. Numbers of specimen of Genus Pinus are yielded in the samples (sample No.3146), and their flora are similar to those of recent. Distinctive characters of flora are many fungi and two cell fungi pollens with projection. Gentianaceae/Euphorbiaceae and similar flora of those are yielded from many samples.
Na-K-ATPase 活性度에 對한 Cyclophosphamide의 影響
柳志明,金光鎭 충남대학교 의과대학 지역사회의학연구소 1985 충남의대잡지 Vol.12 No.1
The sodium and postassium ion-stimulated adenosine triphoshatase(Na-K-ATPase) is the membrane-embedded enzyme responsible for the active transport of sodium and potassium ions through the cell membrane. And this enzyme is an electrogenic pump, transporting 3Na^+ for 2K^+, and is specifically inhibited by the cardiac glycoside, ouabain. Cyelophosphamide to be be used in chemotherapy of neoplastic disease, is generally useful in the treatment of lymphomas, acute lymphocytic leukemia in children, and some solid tumors. This study was attempted to investigate the effects of cyclophorphamide on Na-K-ATPase activity in the red cell ghosts of the rabbits. The results are summarized as follows. 1. Na-K-ATPase activity was significantly inhibited by cyclophosphamide at dose of 20.Omg/ml. 2. Ginseng water extract was significantly decreased the inhibited degree of Na-K-ATPase activity by cyclophosphamide. 3. Mg-ATPase had not any effect under the presence of cyclophosphamide with Ginseng extract or not. From the above results, it suggested that cyclophosphamide inhibited directly Na-K-ATPase activity and ginseng water extract enhanced the inhibited the enzymatic activity.
정신과 입원환자에서 Olanzapine의 처방경향에 대한 연구 : 한국과 미국의 일 대학병원에서 사용비교
박원명,배치운,김선경,채정호,전태연,김광수,유태열 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.1
Objective : Recently, domestic use of olanzapine and the studies for olanzapine have been increased. However, naturalistic studies for the practical use of olanzapine are rare. Therefore, this study was designed to evaluate the prescription trend for olanzapine and its related pharmacological variables at a university hospital in Korea, and to compare with those of university hospital in USA, simultaneously. Methods : Data of 33 Psychiatric inpatients who had been firstly treated with olanzapine at st. Mary's Hospital from October 1999 to March 2000 and of 109 at McLean Hospital, Hanard Medical School, USA from March 1998 to June 1998 were collected, respectively. Data on patient's age, sex, number of past admission, diagnosis distribution, duration of hospitalization, antipsychotic combination, combined psychotropics, combined mood stabilizer, and dosage of olanzapine were analyzed. Results : The mean age and number of past admission were significantly higher at McLean hospital than those of St. Mary's hospital. In terms of diagnosis, olanzapine was most widely prescribed to psychotic disorder, nextly to mood disorder at St. Mary's hospital, but in order of mood disorder, psychotic disorder, and other psychiatric disorder at McLean hospital and, these diagnostic distribution were significantly different. The mean initial dose was similar between two hospitals, but maximal and discharge dose of olanzapine were significantly higher at St. Mary's hospital than those of McLean hospital. In aspects of psychotropic combination , anxiolytic was highly used with statistical significance at St. Mary's hospital but antidepressant and mood stablizer were highly used at McLean hospital. Conclusion : Prescription trend of olanzapine for psychiatric inpatient between two hospital was different, olanzapine was prescribed mainly by diagnosis at St. Mary's hospital but by symptomatic management at McLean hospital. In future, further systematic study should be conducted including various clinical variables to refine these differences.
이광수,김영관,박희진,이재오,명평근 忠南大學校 生命科學硏究院 醫藥品開發硏究所 2006 藥學論文集 Vol.21 No.-
The transplantation of organ, tissues or cells between individuals of different species has been of increasing interest in recent years because the use of animals as organ and tissue donors as a source of transplants would overcome the severe and worsening shortage of human organs available for transplantation. However, There are some major hurdles to the clinical application of xenotransplantation; the immunologic response of the recipient against donor, the physiology of the graft, and the possibility that a xenotransplant might transmit an infection from the source to the recipient. This review describes the unique aspects of the immunological barrier to transplanting organs from non-primates such as pigs into humans, focusing especially on the mechanisms which contribute to immunorecognition, physiology of the rejection and infectious hurdles to xenotransplantation. This communication might be applied to overcoming these hurdles and the possibility that genetic strategies might be used to expand the potential applications of xenotransplantation for the treatment of human disease.
우리 나라 무역업체의 인터넷 무역거래알선사이트의 활성화방안
장면진,윤광운 한국통상정보학회 2000 통상정보연구 Vol.2 No.2
무역거래의 패턴이 최근 크게 변화하고 있는데, 기존 무역거래방식에서 인터넷무역방식으로 그 비중이 확대되면서 인터넷 무역거래알선사이트에 관한 관심과 활용도가 점차 높아지고 있으며 특히 무역거래알선사이트의 구축 및 운영은 국내외의 무역 유관기관과 지방자치단체, 대기업 종합무역상사 및 개별기업을 중심으로 활발히 진행되고 있다. 이에 실제 우리 나라 무역업체들의 사이트 이용 및 현황과 이용만족도 조사를 위해 설문조사를 한 결과, 현재까지 무역업체들이 가장 선호하는 사이트는 무역 유관기관이 운영하는 사이트들이다. 또한 실제 무역거래알선사이트를 이용한 결과와 관련하여 거래알선사이트 제공서비스에 대한 만족은 대상 업체 중 불과 17.9%의 낮은 수준으로서 이렇듯 낮은 만족도를 보이는데는 다음과 같은 문제점들이 있었다. 즉, 정보 인프라 측면에서의 관련정책의 분산, 보안 인프라의 우려, 오프라인 상의 결제 및 세금문제, 인터넷무역 관련 국제협력문제 등을 들 수 있으며, 무역업체의 측면에서는 전문인력의 부족, 최고경영자의 정보화 인프라에 대한 마인드 부족과 업체내의 웹 기반 환경 구축 미흡 등을 들 수 있다. 이상의 문제점들을 개선하기 위한 활성화방안을 살펴보면 첫째, 거래정보 보호기술의 육성 둘째, 무역거래알선사이트의 적극적인 국내외 홍보 셋째, 무역거래알선사이트 관련 분쟁 ·신용조회 등의 통합관리 넷째, 사이트관련 온라인과 오프라인상의 제반환경 개선 및 국제거래 규약 개선 다섯째, 무역거래알선시스템의 효율성제고를 위한 전문인력 양성 및 교육훈련강화 등이 절실히 요망되고 있다.
李政明,李承雨,金侊來 慶熙大學校 1982 論文集 Vol.11 No.-
From the cultivar evaluation experiments conducted in 1981, 'Harvester' and 'Improved Tendergreen' (green-podded cv.) and 'Surecrop Stringless Wax' and 'Royal Burgundy' (yellow-podded cv.) were ranked high on the basis of total pod yield, pod to plant weight ratio, and shape. Number of root nodules per gram dry root varied considerably depending upon the cultivars. Among the cultivars tested, 'Topcrop' and 'Tendercrop' showed the highest nodule number. Ethephon 25-50 ppm, sprayed after considerable pod set, was effective in increasing once-over-harvested pod yield. Number of root nodules per plant or per gram dry root was not influenced by the chemical sprays.