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경구면역을 통한 항원 특이적 IgA 항체 합성에 있어 Cholera Toxin과 Alginate-Microsphere의 효과
송민형,유진수,권명상,성승룡,김용희,권익찬,정서영,양재명,김평현 大韓免疫學會 1996 大韓免疫學會誌 Vol.18 No.3
Secretory (S-IgA) isotype antibody (Ab) is known to play an essential role in the primary defense against various infectious agents in mucosal tissue. However, it has been mostly unsuccessful in the induction of antigen (Ag)-specific IgA Ab response in this site by peroral vaccination. In the present study, we investigated the effect of cholera toxin (CI) as a mucosal adjuvant and alginates-microspheres as a carrier on BSA-specific IgA Ab response in gut-associated lymphoid tissue`(GALT). Peroral immunization of BSA plus CT conferred a great BSA-specific IgA response but IgG response on intestinal fluid (IF). In contrast, intraperitoneal immunization of BSA with Freund's adjuvant readily induced BSA-specific IgG response but IgA response in IF. Further, number of CT specific IgA-secreting cells was substantially increased in mesenteric lymph node when CT-encapsulated-VI alginates-microspheres was administered perorally. Taken together, these results indicate that peroral immunization of soluble antigen in combination of CT or microspheres significantly enhances antigen-specific IgA response in GALT.
김동순,김기홍,전흥용,나승용,최용문,임명순 한국농업정보과학회 2000 농업정보과학 Vol.2 No.1
A diagnosis program of damage-symptom caused by fruit tree pest was developed using Portable Document Format (Docucom PDF). To construct program structure, the damage patterns of plants cased by pests and the morphological rhararteristics of pests were sorted by plant organs. Diagnoses are rallied out by selecting a host species > document symptoms arranged by plant organs > comparing similar symptoms of pests using step by step menu through damage symptoms. In addition, pest information can be accessed either through the scientific or common name of the pest organism.
국내건설공사 사례를 기준한 건설클레임 집중관리 대상선정 프로세스 모델
강명용,민경석 남서울대학교 2007 남서울대학교 논문집 Vol.13 No.3
ABSTRACT : Recently, construction claims have been increased for protecting the rights of construction participants and obtaining the profit of construction projects.There are a lot of unpredictable and uncertain factors in construction projectand these fators cannot be stipulated clearly in contracts. For this reason, a chance of construction claims and disputes is always latent and construction disputes are occurred frequently while construction project are accomplished. Sound contractual relationship between owners and contractors can be maintained and contract clauses can be modified reasonably through construction claims. Although construction claims have theses good effects, construction claims can induce owners and contractors to an antagonism and lead to vast time and economic damages when construction claims develop disputes such as an arbiration and a litigation.
Chromobacterium chocolatum에서의 lipase유전자분리 및 발현
안용현,장지명 단국대학교 2000 論文集 Vol.35 No.-
A kind of vitamin B group. (+)-biotin has been known to have an influence on the growth of an organism and used for feeding material. Biotin has been synthesized by chemical method, and then crystallized with d-ephedrine to get the optically pure form. Lipase have been used for the resolution of chiral compound from racemic mixture. One of intermediates in the biotin synthesis is a diester which is a meso compound. Chromobacterium chocolatum has applied to hydrolyze one methyl ester group. The mono ester was successfully used for the synthesis of (+)-biotin as well as high optical purity. The goal of this research is the genetic cloning of lipase which hydrolyze the dimethyl ester from Chromobacterium chocolatum and identify its enzymatic reaction.
디자인 문제요소의 구조화에 관한 연구 : DEMATEL법과 KJ법의 비교ㆍ분석을 중심으로
최명식,조용호 경희대학교 디자인연구원 2000 예술· 디자인학연구 Vol.3 No.1
If the product design is assembly which reflects requirement of consumers and makers, design can be the best suitable work to combine the requirements. But the problem is the design system is not so simple. As the most of requirement of makers is connected with hardware condition, requirement is fulfilled to a certain extent by product design process applied a certain standard. However that of consumers which involves psychological aspect of human being is very difficult to figure out the entire concept clearly. Being possible to transform the design system to an easy and understandable format with rearrangement and categorization by all means, designing based on this makes a very stable result. In product design, it is the significant problem that how we figure out entire concept and how we solve it. The structural model is the model that makes such a complicated system an easy and understandable visual format. It is contrived form the fact that the human being quickly understands a diagram, beside it can be objectified by a diagram and mathematical preservation. This study aims to extract the more stage structual model by comparative analysis between DEMATEL theory which adapts quantitative analysis and KJ theory which adapts qualitative analysis among many structual models. As a result of analyzing those two theoretical backgrounds, there is a coincidence to build a structural diagram and to extract factors of system in the process of organizing structure but difference is found in the method to treat organizing the structure. The case study to cross check each theory takes analysis of 'Successful factors of Hit Product'. And with application of KJ and DEMATEL same time extract mutual effect of two theories and verifies the theoretical problem and practical problem. In order to select the most practical structual model. 1 put much attention to the process to define the model in the entire case study. As a result of case study, KJ theory is more effective in categorizing and condensing items and DEMATEL theory is effective in recovering the sub system and examining cause and effect among items. Especially in KJ theory, it has not only merit in practical way but also demerit in being abjective, and to cover this structual diagram and to cover frailty. The stable structual model suggested by the result of the case study is the experimental model which reflects experience and instinct of analyser and keeps being objective on the base of qualitative theory.
엄명용,정순영,이원규 한국컴퓨터교육학회 2003 컴퓨터교육학회 논문지 Vol.6 No.4
본 논문에서는 기존의 LCMS에서 사용되는 평가시스템에 퍼지 추론 규칙을 이용한 적응형 퍼지평가시스템(AFES : Adaptie Fuzzy Evaluation System)을 제안한다. AFES 는 학습자가 하나의 학습코스(learning course)에 들어가기 전에 퍼지진단평가(fuzzy diagnostic evealuation)를 통해 학습자에게 코스수준(course level)을 부여한다. 학습자는 코스수준에 따른 맞춤식 학습경로(learning path)로 학습을 종료한 후, 퍼지최종평가(fuzzy final evaluation)를 통해 최종성적(final grade)을 AFES 으로부터 부여 받는다. AFES, 의 가장 큰 특징은 최종성적의 점수 부여 규칙에 있는데, 만약 서로 다른 학습자가 동일한 문제 수에 대하여 같은 수의 정답을 냈더라도, AFES 는 125 가지 퍼지 추론 규칙(fuzzy reasoning rule)에 의거하여 탄력적으로 서로 다른 최종성적을 학습자에게 부여한다. We introduce an AFES(Adaptive Fuzzy Evaluation System) that applies an evaluation system used to existing LCMS(Learning Contents Management System) to a fuzzy reasoning rule. The AFES confers a course level on the learner through a fuzzy diagnostic evaluation before the learner enters a learning course. After the learner completes a learning course through the tailored learning path that is suitable for the learner’s level, the AFES confers a final grade on the learner by means of fuzzy final evaluation. The biggest characteristic of the AFES is a grade rule of the final grade. Although different learners get the same number of correct answers to the same number of questions, AFES flexibiv confers the different final grade on the learner by means of the number of 125’s fuzzy reasoning rules.
공용해,김명숙,최인석 순천향대학교 부설 산업기술연구소 1999 순천향 산업기술연구소논문집 Vol.5 No.2
Low quality character images include a lot of variousness and noises, so the use of a single classifier is difficult to achieve a high recognition performance. For this, we experimented various feature extraction methods suitable for low quality images and constructed a classifier-pair that uses two complementary features. The experimental result using this classifier-pair was very effective for the recognition of low quality character images.
황명신,송용규 한국항공대학교 1994 論文集 Vol.32 No.-
본 연구는 1980년에서 1989년까지 발생된 전세계 각종 항공기 사고에 대하여 사고관련 자료들을 취합하여 사고관련 database를 구축하고, 이들 자료들로 부터 항공기 사고관련 원인을 분석하여 항공기 사고 발생을 방지할 수 있는 자료들을 제공하기 위한 것이다. In this paper we present the Aircraft Accident Database which had been occurred from 1980 to 1989. From this Database, we analyse the possible Aircraft Accident reasons, and represent some special topics on accident.
Poly-β(1,4)-D-glucosamine-g-polyethyleneoxide의 합성 및 물성에 관한 연구
주상명,장광태,성용길 동국대학교 자연과학연구원 1995 자연과학연구 논문집 Vol.15 No.-
Poly-β(1,4)-D-glucosamine derived from poly-β(1,4)-N-acetyl-D-glucosamine by treating with alkaline solution has been reported to be a promising polymer not only in the chemical field but also in biomedical area. Poly-β(1,4)-D-glucosamine used in this experiment was seen about 93 percentage of degree of deacetylation by heterogeneous alkaline soultion. Poly-β(1,4)-D-glucosamine-g-polyethyleneoxide was synthesized by homogeneous method. Various molecular weights of polyethyleneoxide as a hydrophilic and flexible spacer were introduced to Poly-β(1,4)-D-glucosamine to produce Poly-β(1,4)-D-glucosamine-g-polyethyleneoxide. The synthesized copolymers are characterized by FT-IR, elemental analysis, thermogravimetric analyzer, and differential scanning calorimetry.