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공황장애환자에서 광장공포증 동반여부에 따른 스트레스대처방식의 차이
최은영,제영묘,이대수,정영인 대한생물치료정신의학회 2001 생물치료정신의학 Vol.7 No.1
In an attempt to know the factors affecting the development of agoraphobia following panic attacks, the author investigated whether there are differences between coping strategies of panic disorder with and without ago-raphobia. Thirty-seven patients meeting the criteria of DSM-IV panic disorder were divided into 2 subgroups, one group with agoraphobia, another without agoraphobia. Questionaires for the severity of panic symptoms, and of anticipating anxiety for panic attacks, multidimensional coping scale for stress were administered to panic subjects. The results were summarized as follows. 1) Group of panic disorder with agoraphobia complaints trembling or shaking more than group of panic disorder without agoraphobia. 2) There was no differences of degree for the severity of anticipating anxiety between two groups. 3) Group of Panic disorder with agoraphobia had higher score on BDI than Group of panic disorder without agoraphobia. 4) Group of panic disorder with agoraphobia had lower score on active coping, positive interpretation, acceptance than group of panic disorder without agoraphobia, and the differences of these strategies between two groups were not correlated with the score on BDI at the time of investigation. In conclusion, these results suggest that the coping strategies for stress may be a predictor of agoraphobia in patients with panic disorder.
입원 소아환자에서 정맥주사 시 통증 및 불안을 경감시키기 위한 중재연구
김묘진,백정희,서원석,김미영,박선경,박재성 한국의료QA학회 2005 한국의료질향상학회지 Vol.12 No.1
Background : Most hospitalized children will experience physical pain as well as psychological distress. Painful procedure can increase anxiety and fear of pediatric patients and their parents who do not have understanding logical of their disease and hospitalization. This study attempted to identify pain reduction in related to therapeutic intervention by age and environmental improvement. Methods : A total of 194 hospitalized children and their parents were investigated. Data collection period was 3 months from March to May 2004. Four instruments were used to collect the data : Faces Pain Rating Scale(FPRS), Heart rate, Oxygen saturation and Pain behavioral check list. The data were analyzed by a SPSS program and tested χ2-test, t-test, ANCOVA. Results : 1. Age from 0 to 3, the Heart rate, FPRS, Oxygen saturation and Pain behavioral check list were significantly different in theraputic intervention group when compare to control group. 2. Age from 4 to 6, FPRS, Oxygen saturation and Pain behavioral check list were significantly different in theraputic intervention group when compare to control group. But the heart rate were not significantly different when compare to control group. 3. Age from 7 to 9, FPRS and Pain behavioral check list were significantly lower in therapeutic intervention group when compare to control group but Heart rate and Oxygen saturation were not significantly different when compare to control group. Conclusion : The results of this study concludes that most children experience acute pain during IV therapy and it can be reduced by age specific therapeutic intervention and by change of surrounding environment.
제영묘 대한생물치료정신의학회 2004 생물치료정신의학 Vol.10 No.1
자살은 정신장애와 밀접한 관계를 가지고 있고, 정신장애를 가진 환자의 과도한 사망율에 기여한다. 이런 연관성을 자살에 대한 정신 부검 연구와 특정 질환의 자살 사망율을 연구함으로써 평가되어 왔다. 이런 접근법은 자살 당시에 자살자의 90% 이상에서 하나 이상의 정신장애를 가지고 있고, 어떤 정신장애는 자살 위험을 증가시킨다는 것이다. 자살에 있어서 아주 중요한 정신의학적 요인들은 우울장애, 물질사용장애, 정신분열병 등이며, 이에 관한 많은 연구들의 결과를 종합해 볼때, 대부분의 정신장애가 자살 혹은 자살 기도와 뚜렷한 관련이 있다는 것이다. 이 논문에서는 자살과 정신장애에 관한 이전의 여러 문헌을 조사하여 자살과 정신장애의 연관성을 고찰해 보았다. Suicide has a strong association with mental disorder and contributes to the excess mortality of the mentally ill. This association has been assessed by 'psychological autopsy' of consecutive series of suicides and by studying the suicide mortality of particular disorders. These approaches have shown that more than 90% of persons who die from suicide satisfy the criteria for one or more psychiatric disorders at the time they kill themselves and that certain mental illnesses have increased suicide risks. Highly significant psychiatric factors in suicide include depressive disorders, substance abuse, schizophrenia and other mental disorders. Numerous studies have documented a strong association between mental disorders and suicide or suicide attempt. The purpose of this review article is to describe the nature of the relationship between suicide and mental disorders by searching of some previous suicide/mental disorder literature.
제영묘,김명정 大韓神經精神醫學會 1985 신경정신의학 Vol.24 No.1
In order to investigate the presence and the contents of the ideational components of the patients with the anxiety disorders, the authors studied 44 out-and inpatients of anxiety disorders diagnosed by the DSM-Ⅲ criteria at the neuropsychiatric department of Pusan National University Hospital. The results obtained were as follows. Forty three subjects out of 44 patients with anxiety disorders reported to recognize the ideational components of the themes of danger associated with anxiety experiences. 79.5 percent of the subjects had fears of physical disasters; 70.5 percent had psychological and 25 percent, social disasters. Twenty five of them reported two or three themes of danger simultaneously and 18 had themes of either physical or psychological disasters. Particularly there were many who had fear of death and fear of insanity simultaneously. A tendency of more prominent themes of physical disasters was noted in males, cases of acuteonset, cases with panic attacks and those with agoraphobia, and that of psychological disasters in females, cases of insidious onset and generalized anxiety disorder. But statistics failed to show significant difference probably due to insufficient numbers of the subjects. Surveying the contents of each theme, physical disasters were represented by fear of dying or death, psychological disasters by fear of insanity and social disasters by interpersonal rejection or social failure. From these results, the authors suggest that 1) themes of danger are consistently recognied by those with anxiety disorders during experiences of anxiety 2) the content and the intensity of the themes of danger have certain relationship with the intensity of anxiety 3) and the content of the themes of danger can be interpreted as the fear of annihilation.
PCR을 이용한 국내시장에 유통중인 유전자재조합 콩 및 가공식품의 모니터링
김묘영,김재환,김현중,박선희,우건조,김해영 한국응용생명화학회 2003 Applied Biological Chemistry (Appl Biol Chem) Vol.46 No.4
본 연구에서는 PCR을 이용하여 국내시장에 유통중인 원료콩과 가공식품에 epsps 또는 pat 유전자가 삽입된 유전자재조합 콩(GMS)의 사용여부를 모니터링하였다. 이러한 GMS의 검출을 위해 3쌍의 primer set을 제작하였고, 각각의 primer들은 GMS에 삽입된 유전자와 특이적으로 반응하여 PCR산물을 생성하였다. 2001년 표시제가 시행되기 이전에 생산된 총 가공식품과 이후의 제품에 대해 각각 모니터링을 수행하였으며, 표시제 이전에 생산된 제품의 경우 대부분의 미국산 원료에서 esps가 삽입된 GMS가 검출되었으나, 표시제 이후에는 검출되지 않았다. A method using PCR was developed for the monitoring of genetically modified soybean (GMS) and GMS derived foods utilized in the market. We designed 3 pairs of specific oligonucleotide primers based on epsps and pat inserted in GMS and ferritin gene as internal standards. Template DNAs isolated from soybean and processed foods were used for multiplex PCR with 3 primer sets. PCR, used with specific primer sets for GMS detection, showed the amplified DNA fragments with GMS template DNA. In this study, GMS containing epsps was detected from soy processed foods manufactured before GM food labeling system, however, GMS containing epsps or pat was not detected from soy processed foods manufactured after GM food labeling system.
한국판 스미스클라인 비챰의 '삶의 질'척도를 이용한 공황장애 환자의 삶의 질에 관한 연구
이승호,제영묘,김상엽,이대수,최은영 대한생물치료정신의학회 2000 생물치료정신의학 Vol.6 No.1
Objectives : In this study, we researched the change of 'quality of life(QOL)' of patient with panic disorder by KvSBQOL and the predictors affecting the change of 'quality of life'. Methods : 30 outpatient with panic disorder were tested by questionnare for panic disorder and KvSBQOL. Frst, they were classified as when healthy before panic episodes(a point of time 1), when first diagnosed as panic disorder in the psychiatry(a point of time 2), and when treated after diagnosis(a point of time 3). Second, the change of QOL scores in five factors at each point was observed, Third, the correlation between the change of QOL scores(point 3 score-point 2 score) and the several predictors(Onset age, Degree of change in panic symtom, Degree of change in anticipatory anxiety, Degree of change in agraphobia, Spended time to diagnose panic disorder, Duration of treatment) were studied. Results : 1) QOL mean scores of a point of time 1,2 and 3 were 166.267±38.24, 94.367±34.00, 161.367±34.37, respectively. 2) The change of QOL scores in all five factors of KvSBQOL(factor1 Competence, factor2 Psychological well-being, factor3 Stability, factor4 Physical well-being, factor5 Activity)at each point was significant(P<.000). 3) The change of QOL mean scores(point 3 score-point 2 score) have significantly negative correlation with the change of score in anticipatory anxiety but not other predictors. Conclusions : Difference in QOL scores between a point of time 1 and 3 is 4.9, indicating that the psychiatric treatment is important in improvement of QOL, the anticipatory anxiety is an important predictor of QOL(P<.001). and it suggested that diminished anticipatory anxiety is very important to maintain of high QOL in patient with panic disorder.
김혜경,양세화,김묘정,이영수 울산대학교 2001 생활과학논문집 Vol.3 No.1
본 연구는 울산시 거주 가구의 생활양식 전반에 대한 경향을 의 ·식 ·주생활을 비롯하여 가족생활, 소비생활, 건강생활 및 정보지식추구생활을 중심으로 살펴보았다. 이를 통하여 울산이 가지고 있는 지역적인 생활문화의 경향을 파악하고 가족생활 전반에 걸친 가치관 및 생활욕구 패턴을 살펴봄으로써 삶의 질 향상을 위한 지역 정체성 확립에 중요한 기초자료로 활용될 수 있을 것이다. The purpose of this study was to examine the overall life style characteristics of households in Ulsan area through analyzing the current conditions of clothing, food, housing, family life, consuming pattems, health and leisure, and information intelligence pursuit activities. The results of this study provide valuable information to improve the rluality of life by understanding the regional living conditions and examining the values and needs of households in Ulsan.
김철권,조진석,서지민,김용관,김호찬,김현수,김상수,제영묘 大韓神經精神醫學會 1999 신경정신의학 Vol.38 No.3
연구목적 : 정신분열병 환자의 가족이 느끼는 부담을 측정하기 위한 가족부담 척도를 개발하기 위함이다. 방 법 : 200명의 정신분열병 환자 가족과의 비구조적 면담과 외국 부담척도 고찰을 통하여 94문항을 수집하였고 그 다음에 전문가들과 가족들이 문항 및 영역을 분류하고 통합하여 최종적으로 36문항을 선정하였다. 그리고 정신분열병 환자의 가족 135명, 불안장애 환자의 가족 22명, 기분부전장애 및 신체화 장애 환자의 가족 26명, 치매 환자의 가족 49명을 대상으로 신뢰도와 타당도를 검증하였다. 결 과 : 자료분석 결과 검사-재검사 신뢰도, 내적 일치도, 감별타당도 모두 높게 나타났으며, 요인분석을 통해 다섯 가지 구성요인이 추출되었다. 결 론 : 본 가족부담 척도는 정신분열병을 포함한 만성 정신질환을 앓고 있는 환자의 호전과 가족의 부담을 덜어주기 위한 다양한 프로그램의 효과를 검증하는데 유용하게 사용되어질 수 있을 것이다. Objectives : This preliminary study was carried out to develop the Family Burden Scale(FBS) of the schizophrenics. Methods : Ninety-four items were collected by interviewing in a free unstructured format with one relative of each 200 schizophrenic patients and reviewing foreign FBS's. Several professionals and relatives were asked to group and integrate them into several categories. Finally 36 burden items were chosen to constitute a FBS. The FBS was administered to the relatives of 135 schizophrenic, 22 anxiety disorder, 26 dysthymic disorder and somatization disorder, and 49 dementia patients for examining the reliability and validity. Results : The FBS showed high test-retest reliability, internal consistency, and discriminant validity. The results of the factor analysis revealed five-factor solution. Conclusion : The FBS can be used to evaluate the effectiveness of various programs intended not only to reduce decompensation among schizophrenics, but also to alleviate family burden.
24주간 추적하는 임상 연구에서 한국인 남자 알코올 의존 환자의 비재발률
강철중,김성곤,남궁기,조동환,이병욱,최인근,최용성,박성봉,제영묘,김현경,김성연 大韓神經精神醫學會 2006 신경정신의학 Vol.45 No.1
Objetives : In order to provide useful data tbr the further clinical studies with Korean alcohol-dependent patients, enrollment and non-relapse rates were investigated while alcohol-dependent patients wcre followed up for 24 weeks. Methods : The subjects of this study were alcohol-dependent male patients who, for the first time, visited a hospital among 3 groups of hospitals, University Hospital, General Hospital or Mental Hospital, or those who needed to be followed up after discharge from those hospitals. After assigning 12 subjects to each hospital, we investigated enrollment and non-relapse rates while cognitive-behavioral therapy and pharmacotherapy were provided. Results : 1) Forty-eight patients were enrolled and the rate of enrollment was 36.4%. The enrollment rate in the University Hospital group was 52.1%, in the General Hospital group 50.0%. and in the Mental Hospital group 10.4%. 2) In 48 patients, non-relapse rate was 27.1% at 12 week and 18.8% at 24 weeks after starting follow-up. It was 24.4% and 20.0% at 12 and 24 weeks, repectively, in the University Hospital group while the General Hospital group showed 33.3% and 16.7%, respectively, and the Mental Hospital Group showed 20.0% at both 12 and 24 weeks. Conclusion : These results provide important data for further clinical studies of Korean alcohol-dependent patients.