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유남재,이명욱 江原大學校 産業技術硏究所 1996 産業技術硏究 Vol.16 No.-
Centrifuge model tests of cantilever retaining wall were performed to investigate the vertical stress distribution due to selfweight of backfill material. Model tests were carried out to find the effect of arching action on vertical stress distribution by changing the roughness of rigid boundary slope and the distance between retaining wall and boudary slope. A reduced scale model of cantilever retaining wall was made with concrete and Jumunjin Standary Sand with 80% of relative density was used as foundation and backfill material. Centrifuge tests were performed by increasing g-level up to 40 g with measuring vertical stress induced by selfweight of backfill material. Test resutls on vertical stress distribution were analyzed and compared with results of Silo theory.
김명남,박종석 경북대학교 사범대학 부속 중등교육연구소 2005 중등교육연구 Vol.53 No.2
본 연구에서는 제 7차 교육과정에 따라 개발된 11종 10학년 과학교과서 화학영역의 탐구를 분석하여 교과서의 개발과 탐구 학습에 대한 교육적 시사점을 찾고자 한다. 탐구를 탐구 주제, 탐구 실험 실습기기, 탐구 지면 할당량의 3가지 영역으로 나누어 분석하였다. 이를 분석한 결과 탐구의 주제와 탐구 실험 기기 영역에서 실생활과 관련된 주제와 기기를 많이 다루고 있다. 교과서마다 표현 방식이나 내용의 차이가 있고 실험기기의 명칭의 일관성이 없으며 동일한 주제에 시용한 실험 · 실습기기에 차이가 있다. 평균 탐구 지면 할당량이 40.5%이며 그 중 '전해질과 이온(45.2%)'단원이 지면 할당량이 가장 높게 나타났다. 단원별 탐구 지면 할당량의 차이가 많이 나타나는 교과서도 있다. 이러한 부분을 보완하기 위해 교사들은 탐구 내용의 전반적인 내용을 파악해서 누락된 부분을 재구성하여 학생들이 다양한 탐구 활동을 할 수 있도록 하여야 한다. Eleven different kinds of the 10the grade science textbook based on the 7th curriculum were analyzed. Especially, inquiry activity on chemistry field was analyzed in order to provide a clue for the development of new science textbooks and the learning through inquiry activity. Analysis of the inquiry activity for the textbooks was made in view of three separate aspects, i.e., inquiry subject, experimental tools and devices for the activity, and number of pages devoted for the inquiry activity. The result indicates that the inquiry subject and the experimental tools and devices are mostly connected with everyday life. Among the textbooks determined, the way of expression and the contents appear to be different. In addition, there is an inconsistency in the name of the experimental tools and devices used and different tools and devices are used for the experiment with the same subject. In average, 40.5% of the total pages of the textbooks are related to the student's inquiry activity. The most extensively discussed subject in relation to inquiry subject is 'an electrolyte and ion (45.2%).' Some of the textbooks include quite different amounts of pages devoted for the inquiry activity between separate chapters. Thus, in order to improve said problems and thus to develop a more complete science textbook, it is required for science teachers to fully analyze and understand its overall contents and to supplement any missing parts so that the students can be able to successfully carry out the various kinds of scientific inquiry activity.
許南秀,黃光性,金明圭,金昌奎 진주산업대학교 1986 論文集 Vol.24 No.-
This experimental study has been carried out to investigate the coefficient of head loss due to the dividing flow through the T type junction in the Reynolds number ranging from 6×10exp4 to 10exp5. The main duct 50mm in diameter and the dividing ducts of three kinds, respectively 50, 40 and 30mm in diameter, which were PVC pipe, were used. The results obtained are as follows: 1. The experimental formulares obtained by the experimental loss coefficient and weight flow ratio are as follows : ◁수식 삽입▷(원문을 참조하세요) 2. Loss coefficients don't exert a great influence on the change of Reynolds number. 3. As the area ratio increased, the loss coefficients due to the weight flow ratio changed suddenly.
유재남,이명육,이종호 江原大學校 産業技術硏究所 1997 産業技術硏究 Vol.17 No.-
This thesis is an experimental research of investigation behavior of single pile, subjected to the vertical compression loads, using the centrifuge facility located in the geotechnical engineering laboratory in Kangwon National University. Centrifugal model experiments of model pile were carries out changing diameter of model pile, relative density of sandy ground and the gravitational level applied in the centrifuge. Thus, their effects on the load-settlement behavior and the ultimate bearing capacity of pile were investigated. Experimental results obtained from centrifuge model tests were compared with the theoretical or semi-empirical equations to analyze values of ultimate bearing capacity of model pile. When we compare the ultimate bearing capacity of experimental results with the ultimate bearing capacity of theorical results, the experimental results appear more higher in the De Beer method and Meyerhof. Expecially, Terzaghi method is very same as the experimental results normally.
Propylthiouracil에 의한 중증 급성간염 1예
임종주,심미령,이명수,김태현,오석규,안선호,박무림,김남호,박병현,조성구 圓光大學校 醫科學硏究所 2002 圓光醫科學 Vol.17 No.2
PTU에 의한 간염의 발생은 매우 드물게 발생하는 것으로 알려져 있으나 저자들은 Graves씨 병으로 진단 받고 propylthiouracil 투여를 받고있던 환자에서 중증의 급성 간염이 발생한 1예를 경험하였기에 보고하는 바이다. Propylthiouracil is widely used to treat patients with hyperthyroidism. This drug has been associated with severe hepatotoxicity rarely. We presented the case of jaundice and profound liver dysfunction from a 23-year old woman treated with propylthiouracil for hyperthyroidism. Viral, metabolic, and autoimmune liver disease could be excluded and liver biopsy revealed a pattern of acute hepatitis. After discontinuing the drug, there was a progressive resolution of hepatic symptoms and decrease in biochemical data of the liver. Despite propylthiouracil induced hepatitis in rare case, patients receiving propylthiouracil are exposed to develope severe hepatotoxicity. Therefore it might be advisable to monitor level of the transaminase on regular base from patients receiving propylthiouracil.
배양된 정상 인체 각질형성세포에서 자외선 B 조사에 의한 아포프토시스와 p53의 발현
김명남(Myeung Nam Kim),서성준(Seong Jun Seo),홍창권(Chang Kwun Hong),노병인(Byung In Ro),노성욱(Sung Wook Ro),조성인(Sung In Cho) 대한피부과학회 2000 대한피부과학회지 Vol.38 No.4
N/A Cutaneous absorption of ultraviolet B(UVB) in the skin occurs primarily in keratinocyte, causing DNA and protein damage. p53 tumor suppressor gene appeared in the epidermis after UVB irradiation, and the wild type has been known to be responsible for apoptosis and plays an important role in excluding abnormal cells with significant DNA damage. While p53 has been implicated in both DNA repair and apoptosis, it is unclear whether the p53 protein is involved in both of these processes within the same cell. Therefore, UVB-induced apoptosis and changes in p53 expression were studied in cultured normal human keratinocyte to determine that the cellular response to UVB induced DNA damage(DNA repair or apoptosis) correlated with p53 expression. The cultured normal human keratinocytes were irradiated with the doses of UVB(25-150 mJ/cm2) and incubated for various times(3, 6, 12, 24 hour) after radiation. At UVB doses of 100 and 150 mJ/cm2, acridine orange/ethidium bromide(Ao/Eb) staining-positive cells and TUNEL (TdT mediated dUTP-biotin nick end labeling) staining-positive cells increased significantly after 3 hours and 6 hours postirradiation respectively. Twelve hour postirradiation, staining-positive cells increased at each level of UVB-radiation exposure. These results suggest that there were significant influences of UVB doses and time course after irradiation to the number of Ao/Eb and TUNEL staining-positive cells. To determine whether all Ao/Eb and TUNEL-positive cells were actually undergoing apoptosis, cellular DNA was extracted from keratinocytes at 12 hours after UVB irradiation and seperated by electrophoresis on an 2.5% agarose gel to detect the internucleosomal DNA fragmentation(DNA ladder). 'DNA ladder' occurred at every dose of UVB 12 hour after irradiation, but did not appear early after irradiation, suggesting that whether Ao/Eb and TUNEL-positive cells observed early after irradiation were not undergoing apoptosis. Activation of p53 and the response to DNA damage is not observed universally, but is dependent on tissue specificity, species specificity and type of genotoxic damage. To correlate p53 level with UVB-induced apoptosis at the dose of 100mJ/cm2 UVB, p53 levels were determined by western blot analysis. The accumulation of p53 protein was apparent after 6 hours postirradiation, and UVB irradiation caused a dramatic increase in p53 levels at 12 and 24 hours. These results demonstrate that p53 is required for UVB-induced apoptosis in cultured normal human keratinocyte and p53 has a time-dependent effect in the initiation of apoptosis. In this study, the results indicated that a low dose(25mJ/cm2) of UVB irradiation could induce apoptosis in human keratinocyte in vitro and UVB exerts a time-dependent effect on inducing apoptosis. And the results also give support to increasing evidence that p53 may play a role in UVB-induced DNA damage and the induction of apoptosis in cultured normal human keratinocyte and that p53 is involved in the decision process which determines the fate of keratinocyte after UVB -induced DNA damage. (Korean J Dermatol 2000;38(4):481~489)
만성 피부점막 칸디다증 - 증례 보고 및 문헌적 고찰 -
김명남(Myeung Nam Kim),홍창권(Chang Kwun Hong),노병인(Byung In Ro),장진요(Chin Yo Chang) 대한피부과학회 1986 대한피부과학회지 Vol.24 No.5
A 11-year-old girl with chronic mucocutaneous candidiasis(CMCC) has been observee since the age of 4 years. At first(November, 1978) there was a good response to treatment with amphotericin B intravenously of total 300 mg, but not to with oral administration of nystatin and local clotrirnazole cream. Since that time, she bas been admitted on different occasions for further evaluation and therapy because of recurrences. During the most recent hospitalization in October, 1985, she was suffered from herpes zoster in addition to CMCC. We treatecl her with analgesics and intravenous globulin for herpes zoster, and concomitantly with ketoconazole(200 mg/day) and 5-fluarocytosine for 20 days. At the end of this period, she was free of any clinical evidences of CMCC and herpes zoster.