Effect of dissimilar metal SENB specimen width and crack length on stress intensity factor

Murthy A. Ramachandra,Muthu Kumaran M.,Saravanan M.,Gandhi P. 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.7

Dissimilar metal joints (DMJs) are more common in the application of piping system of many industries. A 2- D and 3-D finite element analysis (FEA) is carried out on dissimilar metal Single Edged Notch Bending (DMSENB) specimens fabricated from ferritic steel, austenitic steel and Inconel e 182 alloy to study the behavior of DMJs with constraints by using linear elastic fracture mechanics (LEFM) principles. Studies on DMSENB specimens are conducted with respect to (i) dissimilar metal joint width (DMJW) (geometrical constraints) (5 mm, 10 mm, 20 mm, 30 mm and 50 mm) (ii) strength mismatch (material constraints) and (iii) crack lengths (16 mm, 20 mm and 24 mm) to study the DMJ behavior. From the FEA investigation, it is observed that (i) SIF increases with increase of crack length and DMJWs (ii) significant constraint effect (geometry, crack tip and strength mismatch) is observed for DMJWs of 5 mm and 10 mm (iii) stress distribution at the interfaces of DMSENB specimen exhibits clear indication of strength mismatch (iv) 3-D FEA yields realistic behavior (v) constraint effect is found to be significant if DMJW is less than 20 mm and the ratio of specimen length to the DMJW is greater than 7.4.

Meta-analysis of GSTM1 and GSTT1 Polymorphisms and Risk of Nasopharyngeal Cancer

Murthy, Archana Krishna,Kumar, Vinod,Suresh, K.P. Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.3

Background: Studies of associations between genetic polymorphism of glutathione S-transferase M1 (GSTM1) and glutathione S-transferase T1 (GSTT1) with risk of nasopharyngeal cancer (NPC) have generated conflicting results. Thus, a meta-analysis was performed to clarify the effects of GSTM1 and GSTT1 polymorphisms on the risk of developing NPC. Materials and Methods: A literature search in two electronic databases namely PubMed and EMBASE up to December 2012 was conducted and eligible papers were finally selected based on the inclusion and exclusion criteria. The pooled odds ratio (OR) and presence of heterogeneity and publication bias in those studies were evaluated. Results: A total of 9 studies concerning nasopharyngeal cancer were evaluated. Analyses of all relevant studies showed increased NPC risk to be significantly associated with the null genotypes of GSTMI (OR=1.43, 95%CI 1.24-1.66) and GSTT1 (OR=1.28, 95%CI=1.09-1.51). In addition, evidence of publication bias was detected among the studies on GSTM1 polymorphism. Conclusions: This meta-analysis demonstrated the GSTM1 and GSTT1 null genotypes are associated with an increased risk of NPC.

Ginsenosides: prospective for sustainable biotechnological production

Murthy, Hosakatte Niranjana,Georgiev, Milen I.,Kim, Yun-Soo,Jeong, Cheol-Seung,Kim, Sun-Ja,Park, So-Young,Paek, Kee-Yoeup Springer-Verlag 2014 Applied microbiology and biotechnology Vol.98 No.14

<P>Panax ginseng C.A. Meyer (ginseng) is a well-known medicinal plant that has been traditionally used in the oriental countries for centuries. Wild ginseng is a scarce and rare commodity. Field cultivation of the ginseng plant is a time-consuming and labor-intensive process. Ginsenosides, a group of glycosylated triterpenes, also known as saponins, are the principal bioactive constituents of ginseng. The use of cell and organ culture processes has been sought as a potential alternative for the efficient mass production of ginseng raw material. Various bioprocessing strategies have been developed to date. Cells and adventitious roots have been cultured in large-scale bioreactors and various strategies have been developed accordingly for the enhancement of biomass and ginsenoside accumulation. This review highlights the recent progress in the cultivation of ginseng cell and organ cultures for the production of ginsenosides from bioreactor cultures. In addition, the metabolism and biochemistry of ginsenoside biosynthesis, genomic and proteomic studies in ginseng, metabolic engineering, biosafety, toxicological evaluation, and efficacy assessment of ginseng raw material are also summarized and thoroughly discussed.</P>

Evaluation of mechanical properties for high strength and ultrahigh strength concretes

Murthy, A. Ramachandra,Iyer, Nagesh R.,Prasad, B.K. Raghu Techno-Press 2013 Advances in concrete construction Vol.1 No.4

Due to fast growth in urbanisation, a highly developed infrastructure is essential for economic growth and prosperity. One of the major problems is to preserve, maintain, and retrofit these structures. To meet the requirements of construction industry, the basic information on all the mechanical properties of various concretes is essential. This paper presents the details of development of various concretes, namely, normal strength concrete (around 50 MPa), high strength concrete (around 85 MPa) and ultra high strength concrete (UHSC) (around 120 MPa) including their mechanical properties. The various mechanical properties such as compressive strength, split tensile strength, modulus of elasticity, fracture energy and tensile stress vs crack width have been obtained from the respective test results. It is observed from the studies that a higher value of compressive strength, split tensile strength and fracture energy is achieved in the case of UHSC, which can be attributed to the contribution at different scales viz., at the meso scale due to the fibers and at the micro scale due to the close packing of grains which is on account of good grading of the particles. Micro structure of UHSC mix has been examined for various magnifications to identify the pores if any present in the mix. Brief note on characteristic length and brittleness number has been given.

Anther Culture of Niger

Murthy, H.N.,Ashok Kumar, H.G.,Paek, K.Y. The Korean Society of Plant Biotechnology 2000 식물생명공학회지 Vol.27 No.4

Crack growth analysis and remaining life prediction of dissimilar metal pipe weld joint with circumferential crack under cyclic loading

Murthy, A. Ramachandra,Gandhi, P.,Vishnuvardhan, S.,Sudharshan, G. 한국원자력학회 2020 Nuclear Engineering and Technology Vol.52 No.12

Fatigue crack growth model has been developed for dissimilar metal weld joints of a piping component under cyclic loading, where in the crack is located at the center of the weld in the circumferential direction. The fracture parameter, Stress Intensity Factor (SIF) has been computed by using principle of superposition as K_H + K_M. K_H is evaluated by assuming that, the complete specimen is made of the material containing the notch location. In second stage, the stress field ahead of the crack tip, accounting for the strength mismatch, the applied load and geometry has been characterized to evaluate SIF (K_M). For each incremental crack depth, stress field ahead of the crack tip has been quantified by using J-integral (elastic), mismatch ratio, plastic interaction factor and stress parallel to the crack surface. The associated constants for evaluation of K_M have been computed by using the quantified stress field with respect to the distance from the crack tip. Net SIF (K_H + K_M) computed, has been used for the crack growth analysis and remaining life prediction by Paris crack growth model. To validate the model, SIF and remaining life has been predicted for a pipe made up of (i) SA312 Type 304LN austenitic stainless steel and SA508 Gr. 3 Cl. 1. Low alloy carbon steel (ii) welded SA312 Type 304LN austenitic stainless-steel pipe. From the studies, it is observed that the model could predict the remaining life of DMWJ piping components with a maximum difference of 15% compared to experimental observations.

Barriers to Realization of Forestry Mitigation Potential in India

Murthy, Indu K,Prasad KV, Devi Institute of Forest Science 2018 Journal of Forest Science Vol.34 No.5

Implementation of mitigation options on land is important for realisation of the goals of the Paris Agreement to stabilize temperature at $2^{\circ}C$. In India, the Intended Nationally Determined Contribution (INDC) targets include a forestry goal of creation of carbon sinks of 2.5 to 3 billion tonnes by 2030. There are however, multiple barriers to implementation of forestry mitigation options in India. They include environmental, social, financial, technological and institutional barriers. The barriers are varied not just across land categories but also for a land category depending on its regional location and distribution. In addition to these barriers is the impeding climate change that places at risk realisation of the mitigation potential as rising temperatures, drought, and fires associated with projected climate change may lead to forests becoming a weaker sink or a net carbon source before the end of the century.

The Relationships between CO₂ Emissions, Economic Growth and Life Expectancy

MURTHY, Uma,SHAARI, Mohd Shahidan,MARIADAS, Paul Anthony,ABIDIN, Noorazeela Zainol Korea Distribution Science Association 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.2

The issue of the relationship between environmental degradation and human health has been widely addressed by medical doctors. However, economists have sparsely debated it. The release of carbon dioxide (CO2) into the air can cause several environmental problems and, thus, it can affect human health. Therefore, it is imperative to examine the effect of CO2 emissions on life expectancy in the D-8 countries (Malaysia, Indonesia, Bangladesh, Nigeria, Egypt, Iran, Pakistan, and Turkey) from 1992 to 2017. The panel ARDL method is employed and, then, the PMG estimator is selected. The results show that economic growth, population growth and health expenditure can significantly and positively affect life expectancy, but CO2 emissions can have a significant and negative effect on life expectancy. Since, the major findings reveal that life expectancy can be explained by CO2 emissions. Hence, it is important to formulate policies on reducing CO2 emissions so that life expectancy will not be affected. Energy diversification policies should be formulated or improved in some countries. This is to ensure that the countries are not highly dependent on non-renewable energy that can harm the environment. The government should increase its expenditure on the health sector to save more lives by extend human lifespan.

COMPATIBLE MAPPINGS OF TYPE (A) AND COMMON FIXED POINT THEOREMS

Murthy, P.P.,Chang, S.S.,Cho, Yeol Je,Sharma, B.K. Department of Mathematics 1992 Kyungpook mathematical journal Vol.32 No.2

Prediction of flexural behaviour of RC beams strengthened with ultra high performance fiber reinforced concrete

Murthy A, Ramachandra,Aravindan, M.,Ganesh, P. Techno-Press 2018 Structural Engineering and Mechanics, An Int'l Jou Vol.65 No.3

This paper predicts the flexural behaviour of reinforced concrete (RC) beams strengthened with a precast strip of ultra-high performance fiber-reinforced concrete (UHPFRC). In the first phase, ultimate load capacity of preloaded and strengthened RC beams by UHPFRC was predicted by using various analytical models available in the literature. RC beams were preloaded under static loading approximately to 70%, 80% and 90% of ultimate load of control beams. The models such as modified Kaar and sectional analysis predicted the ultimate load in close agreement to the corresponding experimental observations. In the second phase, the famous fatigue life models such as Papakonstantinou model and Ferrier model were employed to predict the number of cycles to failure and the corresponding deflection. The models were used to predict the life of the (i) strengthened RC beams after subjecting them to different pre-loadings (70%, 80% and 90% of ultimate load) under static loading and (ii) strengthened RC beams after subjecting them to different preloading cycles under fatigue loading. In both the cases precast UHPFRC strip of 10 mm thickness is attached on the tension face. It is found that both the models predicted the number of cycles to failure and the corresponding deflection very close to the experimental values. It can be concluded that the models are found to be robust and reliable for cement based strengthening systems also. Further, the Wang model which is based on Palmgren-Miner's rule is employed to predict the no. of cycles to failure and it is found that the predicted values are in very good agreement with the corresponding experimental observations.