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정호진;주문일;박광호;박태향;김희철 인제대학교 2012 仁濟論叢 Vol.27 No.1
Component-based systems are generally known as useful for maintenance and extension. However, there are a number of difficult aspects in designing them, and skillful knowledge of component-based design is strongly requested. Against the problem, this paper presents a User Interface tool that helps to develop component-based healthcare systems more easily and effectively. This UI tool has been developed, aiming at enabling easier and faster development of such systems. Further it supports standardization and interoperability. We expect that use of the UI tool helps to add, delete, change medical contents, and maintain related systems with less effort and better performance.
열공형과 비열공형 피질하 혈관성 치매에서 위험인자의 차이에 관한 비교 연구
배희준,정지향,유경호,나덕렬,김상윤,최경규,양동원,손의주,이상도,김재우,박경원,김응규,이재홍,박미영,한일우,함동석,최문성,하충건,최성혜,이애영,이병철,한설희 대한치매학회 2003 Dementia and Neurocognitive Disorders Vol.2 No.2
Backgrounds and Objectives: Vascular dementia is a group of dementing disoders arising from various stroke syndrome. Among these. subcortical ischemic vascular dementia (SIVD) is regarded as a relatively distinct clinical entity. However, MRI patterns of SIVD are not homogenous. In some patients, lacunes are dominant, and in others, subcortical white matter changes are. This study was designed to compare risk factor profiles between SIVD with and without multiple lacunes. Methods: We divided 47 subjects (22 males, mean age. 68 years) recruited from VADAPET (Multicenter Trial For Evaluation Of The Changes In the PET Images Of Subcortical Vascular Dementia Patient) study into two groups one with more than 5 lacunes in deep gray matter (lacune group) and the other with 5 or less(non-lacune group) Clinical characteristics and laboratory findings of two groups were compared. Results: Nineteen of 47 patients (40%) belonged to the lacune group. The lacune and non-lacune groups d d not differ in the following variables: age, hypertension, diabetes mellitus, hyperlipidemia heart disease, history of stroke or TIA, history of trauma or major surgery, family history of hypertension stroke, or dementia, age at diagnosis of dementia, body mass index, white blood cell count, ESR, CRP, fibrinogen, hemoglobin A1C, total cholesterol. LDL cholesterol creatinine, proteinuria, glucosuria, and microhematuria. However, male sex, smoking alcohol. hemoglobin, and HDL cholesterol were possibly associated more with lacune group SIVD than with non-lacune group (p<0 1) Multivariate analyses revealed that smoking, hemoglobin, and HDL cholesterol were independent predictors of SIVD with multiple lacunes Conclusion: Our study suggests that SIVD with multiple lacunes may be significantly different in smoking habits hemoglobin, and HDL cholesterol from SIVD without multiple lacunes.
Pendant Crown Ethers 운반체를 이용한 에멀젼 액체막계에서의 Pb^2+ 분리
이종광,이부영,김종향,조문환 慶尙大學校 기초과학연구소 1992 基礎科學硏究所報 Vol.8 No.-
Acryloyl methyl benzo-18-crown-6 단위체는 '4-hydroxymethyl benzo-18-crown-6와 acryloyl chloride을 반응시켜 합성하였다. Poly(acryloyl methyl benzo-18-crown-6)는 벤젠용매하에서 AIBN을 개시제로하여 제조하였다. [0.001mole/L M(NO_3)_n(M^2+ =Na^+, Mg^2+, Ca^2+, Sr^2+, Ba^2+, Zn^2+, Cu^2+, Cd^2+, Mn^n+ 와 Pb^2+)]를 포함한 source phase와 거대고리 리간드 [acryloyl methyl benzo-18-crown-6와 poly(acryloyl methyl benzo-18-crown-6)]와 계면활성제 Span 80을 포함한 toluene 막 그리고 Li_4P_2O_7를 포함하는 receiving phase로 구성되어진 에멀젼 액체막계에서 source phase로 부터 금속이온들의 소멸속도를 연구하였다. 금속이온의 이동에 관한 실험에서, 각 혼합물로 부터 Pb^2+ 이온이 가장 높은 이동율을 나타내었다. Acryloyl methyl benzo-18-crown-6 was synthesized by reacting 4'-hydroxymethyl benzo-18-crown-6 with acryloyl chloride. Poly(acryolyl methyl benzo-18-crown-6) was prepared in benzene by using AIBN as an initiator. The disapperance of metal ions from source phase as a function of time was studied in emulsion liquid membrane systems comprised in an aqueous source phase [0.001mole/L M(NO_3)_n(M^n+ =Na^+, Mg^2+, Ca^2+, Sr^2+, Ba^2+, Zn^2+, Cu^2+, Cd^2+, Mn^2+ 와 Pb^2+)], a toluene membrane containing of the macrocyclic ligand[acryloyl methyl benzo-18-crown-6 and poly(acryloyl methyl benzo-18-crown-6)] and the surfactant Span 80, and an aqueous Li_4P_2O_7 receiving phase. In the experiment for metal ions transport using this emulsioning liquid membrane, the Pb^2+ ion transport was more higher than other metal ions.
( Hyang Mi Mun ),( Nam Surp Yoon ),( Mi Na Kim ),( Jun Hee Woo ),( Soonduck Kim ) 대한임상병리사협회 2009 임상미생물검사학회 발표자료집 Vol.2009 No.-
Background: This study evaluated the clinical characteristics and risk factors associated with community and hospital onset methicillin-resistant Staphylococcus aureus (CO- and HO-MRSA) isolated from patients admitted to a tertiary care hospital in Seoul. Methods: The study was carried out on MRSA isolated from clinical specimens of patients admitted into the wards and the intensive care unit in a 2,200-bed tertiary care hospital from January 1st through December 31st, 2007. In order to identify the risk factors associated with MRSA acquisition, the medical records were reviewed. All statistics were computed using SPSS version 14.0. Results: Of the 835 MRSA isolates, 179 (21.4%) were CO-MRSA and 656 (78.6%) were HO-MRSA. Of the 179 CO-MRSA isolates, 6 (3.4%) were community acquired (CA) MRSA. A multiple logistic regression analysis showed that a history of using medical device or antibiotics within 1 year before the isolation of MRSA were significant risk factors for HO-MRSA, and a history of hospitalization within 1 year before the isolation of MRSA was a significant risk factor for CO-MRSA. Analysis on the antibiotics administered within 1 year before the isolation of MRSA showed that levofloxacin, macrolides, 1st generation cephalosporins, 3rd generation cephalosporins, 4th generation cephalosporins, vancomycin, metronidazole, and carbapenem were all significant risk factors for HO-MRSA and that TMP/SMX was a significant risk factor for CO-MRSA. Of the 6 CA-MRSA isolates, 1 (16.7%) was the pathogen responsible for soft tissue infection. No patients died from the CA-MRSA infection. Discussion: MRSA isolated from clinical specimens of patients admitted into the wards and the ICU in a tertiary care hospital was usually HO-MRSA. CO-MRSA and HO-MRSA usually had at least one of the risk factors associated with MRSA acquisition. As for CO-MRSA, it was mainly HACO-MRSA.
연구논문 : 호텔 직원의 친환경 호텔 환경속성 지각 차이에 관한 연구 -서울시내 특1급 호텔 직원을 대상으로-
오문향 ( Mun Hyang Oh ) 대한관광경영학회 2012 觀光硏究 Vol.27 No.1
본 연구는 서울시내 특1급호텔의 직원들을 대상으로 ``호텔 직원의 친환경 호텔 속성 지각에 관한 연구``를 수행하여 기업의 친환경 경영정책 수립을 위한 기초자료를 제공하고자 하였다. 연구 결과에 따르면, 첫째, 직원의 인구통계학적 특성에 따라 친환경 인식 수준이 다르게 나타날 수 있음을 확인하였다. 특히, 기혼 직원들이 미혼 직원들보다 높은 평균값을, 상대적으로 높은 연령대의 직원들이 높은 수준의 친환경 인식 수준을 가진 것으로 나타났다. 둘째, 직원의 일반적 특성에 따라 친환경 인식 수준이 다르게 나타났다. 특히, 소속부서, 직위, 근무연수 등에 따라 친환경 지각 수준에 유의한 차이를 보였다. 셋째, 기존 선행연구들과는 달리 직원의 성별, 학력, 1년 간 받은 환경교육의 횟수, 고용형태 등에 대해서는 유의한 차이가 드러나지 않는 것으로 나타났다. 본 연구의 학문적 시사점으로는, 첫째, 서울시내 특1급 호텔의 직원들의 친환경 호텔 환경속성 지각 수준을 살펴봄으로써 친환경 호텔로의 탈바꿈을 위한 직원들의 마인드가 평균 이상(3.403-4.365(5점 척도)의 범위)은 되지만, 소속부서, 직위, 연령, 근무연수 등에 따라 차이를 보이고 있는 것이 확인되었다. 둘째, 기존 친환경 호텔 관련 연구에서는 호텔고객 측면에서의 친환경 호텔 환경속성 지각 수준에만 초점을 두었다면, 본 연구에서는 내부고객이자 이해관계자에 해당하는 직원들을 대상으로 하여 환경속성 지각 수준을 살펴봄으로써 기존 연구의 한계점을 보완하였다. 셋째, 선행연구에서 채택한 친환경 호텔 환경 속성들을 바탕으로 연구자가 재정리한 속성들을 통해 비교적 높은 신뢰도를 지닌 7개 요인들을 추출하였다. 마지막으로, 호텔 직원의 인구통계학적 특성 및 일반적 특성은 친환경 호텔 환경속성 지각에 영향을 미치는 변수임을 확인하였으며, 카이검증을 통해 직원별로 각기 다른 친환경 호텔 환경속성 지각 수준을 가지고 있음을 알 수 있었다. This study attempts to develop fundamental data about ``the awareness of staff members to their hotel``s eco-friendly attributes.`` Our research produced several findings we would like discuss: First of all, there were some difference in perceptions of environment attributes of eco-friendly hotel. Married staff had higher awareness of a hotel`s green attributes compared to unmarried staff members. Also, Older staff members were more aware than counterparts in their twenties. Secondly, there were also had some difference in environmentally responsible attributes. The marketing department and the food & beverage department had a higher level of awareness than the room maintenance department, management department, or facilities department. Also, relatively low position staff members had lower awareness compared to those in higher positions. Third, inclusion of conservation in training, temporary or permanent worker status, gender, and education level had little to no effect on the awareness of eco-friendly attributes. According to these results, we suggest the addition of marketing education to the conservation training already in place and the further development of our manual to reflect our commitment to being environmentally responsible. These efforts will contribute to our goal of satisfying our customers as well as bolstering long-term profits.
Lee, Mun-Hyang The Korean Pediatric Society 2012 Clinical and Experimental Pediatrics (CEP) Vol.55 No.9
The ketogenic diet has been widely used and proved to be effective for intractable epilepsy. Although the mechanisms underlying its antiepileptic effects remain to be proven, there are increasing experimental evidences for its neuroprotective effects along with many researches about expanding use of the diet in other neurologic disorders. The first success was reported in glucose transporter type 1 deficiency syndrome, in which the diet served as an alternative metabolic source. Many neurologic disorders share some of the common pathologic mechanisms such as mitochondrial dysfunction, altered neurotransmitter function and synaptic transmission, or abnormal regulation of reactive oxygen species, and the role of the ketogenic diet has been postulated in these mechanisms. In this article, we introduce an overview about the expanding use and emerging trials of the ketogenic diet in various neurologic disorders excluding intractable epilepsy and provide explanations of the mechanisms in that usage.