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Seismic performance of R/C structures under vertical ground motion
Selcuk Bas,이종한,Mukadder Sevinc,Ilker Kalkan 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.20 No.4
The effects of the vertical component of a ground motion on the earthquake performances of semi-ductile high-rise R/C structures were investigated in the present study. Linear and non-linear time-history analyses were conducted on an existing in-service R/C building for the loading scenarios including and excluding the vertical component of the ground motion. The ratio of the vertical peak acceleration to the horizontal peak acceleration (V/H) of the ground motion was adopted as the main parameter of the study. Three different near-source earthquake records with varying V/H ratio were used in the analyses. The linear time-history analyses indicated that the incorporation of the vertical component of a ground motion into analyses greatly influences the vertical deflections of a structure and the overturning moments at its base. The lateral deflections, the angles of rotation and the base shear forces were influenced to a lesser extent. Considering the key indicators of vertical deflection and overturning moments determined from the linear time-history analysis, the non-linear analyses revealed that the changes in the forces and deformations of the structure with the inclusion of the vertical ground motion are resisted by the shear-walls. The performances and damage states of the beams were not affected by the vertical ground motion. The vertical ground motion component of earthquakes is markedly concluded to be considered for design and damage estimation of the vertical load-bearing elements of the shear-walls and columns.
Ozgul Malcok Gürel,Muhammed Bora Demircelik,Mukadder Ayse Bilgic,Hakki Yilmaz,Omer Caglar Yilmaz,Muzaffer Cakmak,Beyhan Eryonucu 대한심장학회 2015 Korean Circulation Journal Vol.45 No.5
Background and Objectives: The red blood cell distribution width (RDW) has been found to be associated with cardiovascular morbidity and mortality. The objective of this study was to determine whether the RDW measures are associated with the coronary artery calcification score (CACS) in patients who did not present with obvious coronary heart disease (CHD). Subjects and Methods: A total of 527 consecutive patients with a low to intermediate risk for CHD but without obvious disease were enrolled in this study. The study subjects underwent coronary computerized tomography angiography and CACS was calculated. The patients were divided into two groups based on CACS: Group I (CACS≤100) and Group II (CACS>100). The two groups were compared in terms of classic CHD risk factors and haematological parameters, particularly the RDW. Results: Group I patients were younger than Group II patients. The Framingham risk score (FRS) in patients of Group II was significantly higher than that in patients of Group I. Group II patients had significantly elevated levels of haemoglobin, RDW, neutrophil count, and neutrophil/lymphocyte ratio compared with Group I patients. CACS was correlated with age, RDW, and ejection fraction. In the multivariate analysis, age, RDW, and FRS were independent predictors of CACS. Using the receiver-operating characteristic curve analysis, a RDW value of 13.05% was identified as the best cut-off for predicting the severity of CACS (>100) (area under the curve=0.706). Conclusion: We found that the RDW is an independent predictor of the CACS, suggesting that it might be a useful marker for predicting CAD.
Rare Cause of Hematochezia in Children: Solitary Rectal Ulcer, Single Center Experience
Fatma İlknur Varol,Şükrü Güngör,Mukadder Ayşe Selimoğlu,Emine Şamdancı 대한소화기학회 2024 대한소화기학회지 Vol.83 No.1
Background/Aims: Solitary rectal ulcer syndrome (SRUS) can be overlooked, diagnosed late, or misdiagnosed, particularly in childhood. This study reviewed the 13-year experience of the authors’ institution to increase clinicians' awareness of SRUS in the presence of symptoms. This paper reports the endoscopic and histopathological findings in children presenting with hematochezia. Methods: The clinical and laboratory findings of 22 patients diagnosed with biopsy-proven SRUS in the authors’ clinic between 2007 and 2020 were evaluated retrospectively. Results: The mean age at diagnosis was 12.5±2.6 years, and 59.1% of the patients were male. The median time of diagnosis was 24 months. A single ulcer lesion was found by colonoscopy in 18 patients (81.8%), two ulcers in two patients (9%), and more than two ulcers in two patients (9%). The pathology reports of all biopsies taken from the lesions were consistent with a solitary rectal ulcer. In the first stage, the treatment was started with toilet training, a high-fiber diet, and laxatives. In 11 patients (50%) who did not respond to the initial treatment, a 5-ASA enema was added. A glucocorticoid enema was added to treatment in five patients (22%) whose complaints did not regress despite this treatment. Clinical remission was achieved in five of the patients (18.1%). The time to diagnosis was significantly shorter in those in remission than those not in remission (p=0.04). Conclusions: This study is the first large series on Turkish children. An increased awareness of SRUS in children will increase the rate of early diagnosis and treatment, allowing remission in more patients.
The Influence of Cigarette Smoke on the Epithelium of the Vestibule: an Electron Microscopic Study
Mukaddes E?refo?lu,Erol Selimo?lu,Muammer E?refo?lu,?zgen Vuraler 연세대학교의과대학 2003 Yonsei medical journal Vol.44 No.4
It is known that cigarette smoke induces cytological alterations on the respiratory and olfactory mucosa of the nasal cavity. We evaluated whether cigarette smoking had adverse effects on the epithelium of the vestibule, in the absence of any published ultrasutructural studies. We evaluated ten patients suffering from septum deviation, eight of whom were long-term smokers. While each layer of the epithelium obtained from the non-smokers consisted of a homogeneous cell population, each from the long-term smokers consisted of a heterogeneous cell population. The most prominent changes occurred in the shape and size of the cells and nuclei, the number and length of the cytoplasmic projections, the number and distribution pattern of the desmosomes, and the width of the intercellular spaces. We concluded that cigarette smoke produces hyperplastic and dysplastic changes, important factors related with cancer development, on the epithelium of the vestibule.
ROUGH STATISTICAL CONVERGENCE IN 2-NORMED SPACES
( MUKADDES ARSLAN ),( Erdinç Dündar ) 호남수학회 2021 호남수학학술지 Vol.43 No.3
In this study, we introduced the notions of rough statistical convergence and defined the set of rough statistical limit points of a sequence and obtained statistical convergence criteria associated with this set in 2-normed space. Then, we proved that this set is closed and convex in 2-normed space. Also, we examined the relations between the set of statistical cluster points and the set of rough statistical limit points of a sequence in 2-normed space.
Yildirim Süleyman,Saygili Saba Mukaddes,Süneçli Onur,Kirakli Cenk 대한마취통증의학회 2024 Korean Journal of Anesthesiology Vol.77 No.1
Background: Alveoli tend to collapse in patients with acute respiratory distress syndrome (ARDS). Endotracheal aspiration may increase alveolar collapse due to the loss of end-expiratory lung volume (EELV). We aimed to compare the loss of EELV after open and closed suction in patients with ARDS.Methods: This randomized crossover study included 20 patients receiving invasive mechanical ventilation for ARDS. Open and closed suction were applied in a random order. Lung impedance was measured using electric impedance tomography. The change in end-expiratory lung impedance end of suction and at 1, 10, 20, and 30 min after suction, was used to represent the change in EELV. Arterial blood gas analyses and ventilatory parameters such as the plateau pressure (Pplat), driving pressure (Pdrive), and compliance of the respiratory system (CRS) were also recorded.Results: Less volume loss was noted after closed suction than after open suction (mean ΔEELI: −2661 ± 1937 vs. −4415 ± 2363; mean difference: −1753; 95% CI [−2662, −844]; P = 0.001). EELI returned to baseline 10 min after closed suction but did not return to baseline even 30 min after open suction. After closed suction, the Pplat and Pdrive decreased while the CRS increased. Conversely, the Pplat and Pdrive increased while the CRS decreased after open suction.Conclusions: Endotracheal aspiration may result in alveolar collapse due to loss of EELV. Given that closed suction is associated with less volume loss at end-expiration without worsening ventilatory parameters, it should be chosen over open suction in patients with ARDS.
Erkan Caglar,Deniz Atasoy,Mukaddes Tozlu,Engin Altınkaya,Serkan Dogan,Hakan Senturk 대한소화기내시경학회 2020 Clinical Endoscopy Vol.53 No.1
Background/Aims: Altered anatomy is a challenge in endoscopic retrograde cholangiopancreatography (ERCP) for patients withBillroth II anastomosis. In this study, we investigated the overall success and role of endoscopist experience. Methods: Data of patients who underwent ERCP between 2014 and 2018 after a previous Billroth II operation were retrievedretrospectively from 2 tertiary ERCP centers. The procedures were performed by 2 endoscopists with different levels of experience. Clinical success was defined as extraction of the stone, placement of a stent through a malignant stricture, and clinical and laboratoryimprovements in patients. Results: Seventy-five patients were included. The technical success rate was 83% for the experienced endoscopist and 75% for theinexperienced endoscopist (p=0.46). The mean (±standard deviation) procedure time was 23.8±5.7 min for the experienced endoscopistand 40.68±6.07 min for the inexperienced endoscopist (p<0.001). In total, 3 perforations (4%) were found. The rate of afferent loopperforation was 6.25% (1/16) for the inexperienced endoscopist and 0% (0/59) for the experienced endoscopist (p=0.053). Conclusions: ERCP in patients who had undergone Billroth II gastrectomy was time consuming for the inexperienced endoscopistwho should beware of the unique adverse events related to ERCP in patients with altered anatomy.