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Evaluation of sprout growth traits and flavonoid content in common and tartary buckwheat germplasms
Muhammad Rauf,윤혜명,이수경,현도윤,이명철,오세종,최유미 한국육종학회 2019 Plant Breeding and Biotechnology Vol.7 No.4
Buckwheat sprouts are used as a functional food in several countries owing to their soft and slightly crispy texture andattractive fragrance. They possess excellent anti-oxidant activity and are rich in amino acids, minerals, and flavonoids; however, sproutgrowth and flavonoid content may vary among buckwheat germplasms. The present study was performed to evaluate 87 common and13 tartary buckwheat germplasms for sprout growth traits and rutin and quercetin content. We found that the common type buckwheatsprouts had considerably higher leaf length and width, fresh shoot weight, and extract weight than those of tartary buckwheat sprouts,but the rutin and quercetin content was significantly higher in tartary buckwheat sprouts. The rutin content ranged from 323.7 to 750.6 mg/100 g DW in common buckwheat sprouts and 2220 to 3185 mg/100 g DW in tartary buckwheat sprouts. Similarly, the quercetin contentranged from 0.27 to 1.82 and 4.76 to 30.41 mg/100 g DW in common and tartary buckwheat sprouts, respectively. Additionally, therewas no significant correlation between the growth traits and rutin content in common buckwheat sprouts, whereas, the leaf length oftartary buckwheat sprouts showed a significant positive correlation with the rutin content. This information can be used by plantbreeders and plant geneticists to study the genetic and genomic approaches for buckwheat breeding program.
Changing Trends of Adult Lymphoma in the Kingdom of Saudi Arabia - Comparison of Data Sources
Rauf, Muhammad Shahzad,Akhtar, Saad,Maghfoor, Irfan Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.5
Background: Lymphoma is one of the most common malignancies affecting the young Saudi population. This disease has diversified pathologies and clinical stages that necessitate well optimized clinical management. Regular updates of epidemiological behavior of lymphoma from various parts of the world are available but studies from the Kingdom of Saudi Arabia (KSA) in this field are not consistent. Objectives: The aim of this study was to investigate the current trends in presentation and distribution of lymphoma with special reference to incidence and mortality, gender, age, histopathological subtypes, and clinical stages at King Faisal Specialist Hospital and Research Centre (KFSH&RC). Materials and Methods: Our study included lymphoma data from Saudi Cancer Registry, and relative comparison against KFSH&RC tumor registry data, Gulf country data and International Agency for Research on Cancer data. Results: Common tumors in the West (lung, colon, and prostate) were found to be much less frequent in KSA while leukemia, lymphoma and thyroid cancers were more common. Non-Hodgkin Lymphoma (NHL) ranked 3rd most common cancer with age-adjusted incidence of 6/100,000. Estimated age adjusted mortality was 4/100,000 in KSA. There was a peak rise in incidence of lymphoma in 1997-2007. Most common NHL was diffuse large B cell lymphoma at KFSH&RC. A total of 434 cases were diagnosed in 5 years with 55% of them at advanced stage and 35% demonstrating bulky disease and high risk. KFSH&RC registered 35% of Hodgkins and 21% of total NHL identified in entire Saudi Cancer Registry, 2009. Conclusions: Results of this study are very unique, and reveal diverse trends. The findings provide valuable insights in the understanding of current epidemiological features of lymphoma in this part of the world.
Novel MoP/HY catalyst for the selective conversion of naphthalene to tetralin
Muhammad Usman,Dan Li,Rauf Razzaq,Muhammad Yaseen,Chunshan Li,Suojiang Zhang 한국공업화학회 2015 Journal of Industrial and Engineering Chemistry Vol.23 No.-
MoP catalyst supported on HZSM-5, HBeta and HY were prepared by wet impregnation and temperature programmed reduction (H2-TPR), applied for the conversion of naphthalene to tetralin, and characterized by XRD, SEM, TEM, BET, H2-TPR, and NH3-TPD. Catalytic tests revealed the highest selectivity to tetralin was observed over MoP/HY with a naphthalene conversion of 85% and a tetralin selectivity of 99%. The effect of temperature and liquid hourly space velocity (LHSV) was also studied. Well dispersed and small particles of MoP, reduced pore size and weak acidity of HY contribute to enhanced catalytic activity and selectivity in conversion of naphthalene to tetralin.
Muhammad Ahmed BILAL,Hadi Hassan KHAN,Muhammad IRFAN,S.M. Nabeel Ul HAQ,Manzoor ALI,Ali KAKAR,Wahab AHMED,Abdul RAUF 한국유통과학회 2021 The Journal of Asian Finance, Economics and Busine Vol.8 No.1
This paper attempts to study the impact of Financial Literacy on Youth Entrepreneurial Intent in Pakistan. A closed-ended self-administered structured questionnaire covering financial literacy, computer knowledge, financial attitude, and financial knowledge with Entrepreneurial Intent was collected from young entrepreneurs. The research tried to investigate the education level with computer skill to inspect the effect of financial literateness on young generation Entrepreneurial Intent in the context of Pakistan. The research model was tested using PLS-SEM and authenticating a measurement model through the advanced methodology and their association with Entrepreneurial Intent. Results revealed that financial literacy and its two parts (financial attitude and financial knowledge) have a positive impact on Entrepreneurial Intent. The size of the joint impact of financial literacy and its components on Entrepreneurial Intent was assessed to be adequate. Entrepreneurial Intent is essential for creating new firms to maintain economic development. Furthermore, it is determined in this research that if youth has better financial knowledge and financial attitude, the probability of Entrepreneurial Intent increases. This suggests that if the youth in Pakistan desire to attain a higher limit of Entrepreneurial Intent, they must implement financial literacy models for enhancing and promoting their current Entrepreneurial Intent.
Evaluation of Major Dietary Ingredients in Diverse Oats (Avena sativa L.) Germplasm
Muhammad Rauf,윤혜명,이수경,신명재,고호철,이명철,오세종,현도윤,허온숙,최유미 한국작물학회 2019 Journal of crop science and biotechnology Vol.22 No.5
Oat (Avena sativa L.) is one of the world’s most important cereal crops, owing to its use as an important source of essential nutrients for both humans and animals. In the present study, the main nutritional components of 975 oat germplasm accessions were investigated. Crude fiber content ranged from 0.08 to 6.79%, with a mean of 2.14%, whereas total dietary fiber content ranged from 5.32 to 17.59%, with a mean of 11.01%, β-glucan content ranged from 1.02 to 6.33%, with a mean of 3.05%, and lipid content ranged from 1.41 to 8.72%, with a mean of 4.73%. Furthermore, most of the germplasm accessions exhibited 1-3% crude fiber content in the range of 1-3%, 9-12% total dietary fiber content, 2-4% β-glucan content, and 4-5% lipid content. Both the crude fiber and total dietary fiber contents were significantly but weakly correlated with β -glucan content, and the nutritional contents of germplasm accessions from different countries varied significantly. The highest mean crude fiber, total dietary fiber, β-glucan, and lipid contents were exhibited by the germplasm accessions collected from Canada, the UK, the Netherlands, and Turkey, respectively, and the accessions that exhibited the highest crude fiber (n=4), total dietary fiber (n=7), β-glucan content (n=5), and lipid (n=12) contents were identified. These findings provide valuable information for breeding programs aiming to improve the nutritional value of already existing high-yielding oat cultivars.
Tayeb, Muhammad,Rauf, Fozia,Ahmad, Khurshid,Khan, Faiz Muhammad Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.4
Background: The objectives of the study were to: 1) determine the frequency of incidental malignancy in unsuspected/grossly normal looking gall bladders; 2) determine the frequency of malignancy in suspected/grossly abnormal looking gall bladders. Materials and Methods: This prospective, cross sectional study was carried out at a tertiary care hospital in Pakistan, during a four year period (Jan 2009-dec2012). All the cholecystectomy cases performed for gallstone diseases were examined initially by a surgeon and later on by a pathologist for macroscopic abnormalities and accordingly assigned to one of the three categories i.e. grossly normal, suspicious, abnormal/malignant. Frequency of incidental carcinoma in these categories was observed after receiving the final histopathology report. Results: A total of 426 patients underwent cholecystectomy for cholelithiasis, with a 1:4 male: female ratio. Mean age of the patients was 45 years with a range of 17-80 years. The frequency of incidental gallbladder carcinoma was found to be 0.70 %(n=3). All the cases of gallbladder carcinoma were associated with some macroscopic abnormality. Not a single case of incidental carcinoma gallbladder was diagnosed in 383 'macroscopically normal looking' gallbladders. Conclusions: Incidental finding of gall bladder cancer was not observed in any of macroscopically normal looking gall bladders and all the cases reported as carcinoma gallbladder had some gross abnormality that made them suspicious. We suggest histopathologic examination of only those gall bladders with some gross abnormality.
Abdul Haleem,Sidra Bibi Syaal,Muhammad Ajmal,Jaweria Ambreen,Sajid Rauf,Nasir Ali,Saz Muhammad,Afzal Shah,Muhammad Abid Zia,Muhammad Siddiq 한국화학공학회 2020 Korean Journal of Chemical Engineering Vol.37 No.4
Here in, we demonstrate facile fabrication of silver and palladium nanoparticles in dual responsive poly(Nisopropylacrylamide- co-2-Acrylamido-2-methylpropane sulfonic acid) microgel with temperature- and pH-dependent catalytic potential. Palladium-based catalyst showed better catalytic efficiency as compared to silver-based catalyst for degradation of Rhodamine-B and P-Nitrophenol in aqueous medium under the same set of reaction conditions. The responsive nature of the microgel was found to be useful to tune the catalytic activity of the as-prepared catalysts, and reduction rate was enhanced with the pH and temperature elevation of the reaction medium; however, the increasing trend was slowed in the volume phase transition region of the microgel. Under a specific set of reaction conditions, the reduction of Rhodamine-B was as fast as 0.968 and 0.571 min1 when catalyzed with palladium and silver based catalysts, respectively. The hydrodynamic radius of the particles of microgel support was found to be in the range of 65- 180 nm when pH and temperature of the medium were varied in the range of 2-12 and 25-45, respectively. The estimated diameter of silver and palladium nanoparticles fabricated in the microgel support under the same set of reaction conditions was 9-15 and 7-11 nm, respectively.
Rauf, Abdur,Uddin, Ghias,Raza, Muslim,Ahmad, Aftab,Jehan, Noor,Ahmad, Bashir,Nisar, Muhammad,Molnar, Joseph,Csonka, Akos,Szabo, Diana,Khan, Ajmal,Farooq, Umar,Noor, Mah Asian Pacific Journal of Cancer Prevention 2016 Asian Pacific journal of cancer prevention Vol.17 No.4
Pistagremic acid (PA) is a bioactive triterpenoid isolated from various parts of Pistacia integerrima plants. The aim of this research was to investigate PA for reversion of multidrug resistant (MDR) mediated by P-glycoprotein using rhodamine-123 exclusion study on a multidrug resistant human ABCB1 (ATP-binding cassette, sub-family B, member 1) gene-transfected mouse T-lymphoma cell line in vitro. Results were similar to those with verapamil as a positive control. Docking studies of PA and standard Rhodamine123 were carried out against a P-gp crystal structure which showed satisfactory results. Actually, PA cannot bind exactly where co-crystallized ligand of P-gp is already present. However, the docking study predicted that if a compound gives a lesser score then it may have some potency. The docking scores of PA and Rhodamine were similar. Therefore, we can conclude that there are certain important chemical features of PA which are responsible for the inhibiting potency of P-gp.