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      • Observer Based Tip Tracking Control of Two-Link Flexible Manipulator

        Mosayebi Masoud,Ghayour Mostafa,Shariati Nia Mostafa 제어로봇시스템학회 2010 제어로봇시스템학회 국제학술대회 논문집 Vol.2010 No.10

        In this paper, a non-linear observer is designed to estimate the time derivatives of the flexural degrees of freedom that are not conveniently or economically accessible. A non-linear control strategy is developed based on input-output linearization. This is achieved by defining new outputs near the end point of the arm that results in stable zero dynamics. The control objective is considered tip position tracking of a desired trajectory. Stability of the observer error dynamics is proved by Lyapunov theorem. The controller performance is demonstrated by numerical simulation on a two-link flexible manipulator with a tip load in vertical plane.

      • KCI등재

        Partial oxidation of butane to syngas using nano-structure Ni/zeolite catalysts

        Amir Mosayebi,Reza Abedini 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

        In this study, performance of nano-structure Ni over different zeolite supports in partial oxidation of butane was investigated. First, partial oxidation process was performed without catalyst to evaluation of optimal conditions. For in situ reduction of catalysts, H2 produced from homogenous reaction was used. Catalytic partial oxidation was carried out using nano-structure nickel catalysts supported by ZSM5, mordenite and Y. Each catalyst was synthesized through reverse microemulsion method. The catalysts were characterized by BET surface area, XRD, SEM and TGA. Highest butane conversion ( 89%) observed in the presence of Ni/Y catalyst. Also Ni/Y shows the highest overall selectivity to CO and H2 as the most desired partial oxidation products. Results from TGA showed that the minimum quantity of formatted coke was related to Ni/Y, which confirmed the stability of butane conversion versus time for this catalyst.

      • KCI등재

        Changes in Synaptic Transmission and Long-term Potentiation Induction as a Possible Mechanism for Learning Disability in an Animal Model of Multiple Sclerosis

        Ghasem Mosayebi,Mohammad Reza Soleyman,Mostafa khalili,Masoumeh Mosleh,Mohammad Reza Palizvan 대한배뇨장애요실금학회 2016 International Neurourology Journal Vol.20 No.1

        Purpose: Multiple sclerosis (MS) is a chronic inflammatory demyelinating disease of the central nervous system. It has been shown that memory deficits is common in patients with MS. Recent studies using experimental autoimmune encephalomyelitis (EAE) as an animal model of MS have shown that indicated that EAE causes hippocampal-dependent impairment in learning and memory. Thus far, there have been no in vivo electrophysiological reports describing synaptic transmission in EAE animals. The aim of the present work is to evaluate the synaptic changes in the CA1 region of the hippocampus of EAE rats. Methods: To evaluate changes in synaptic transmission in the CA1 region of the hippocampus of EAE rats, field excitatory postsynaptic potentials (fEPSPs) from the stratum radiatum of CA1 neurons, were recorded following Schaffer collateral stimulation. Results: The results showed that EAE causes deficits in synaptic transmission and long-term potentiation (LTP) in the hippocampus. In addition, paired-pulse index with a 120 msec interstimulus interval was decreased in the EAE group. These findings indicate that EAE might induce suppression in synaptic transmission and LTP by increasing the inhibitory effect of GABAB receptors on the glutamate-mediated EPSP. Conclusions: In conclusion, influence of inflammation-triggered mechanisms on synaptic transmission may explain the negative effect of EAE on learning abilities in rats.

      • KCI등재

        Vehicle/track dynamic interaction considering developed railway substructure models

        Seyed-Ali Mosayebi,Jabbar-Ali Zakeri,Morteza Esmaeili 국제구조공학회 2017 Structural Engineering and Mechanics, An Int'l Jou Vol.61 No.6

        This study is devoted to developing many new substructure models for ballasted railway track by using the pyramid model philosophy. As the effect of railway embankment has been less considered in the previous studies in the field of vehicle/track interaction, so the present study develops the pyramid models in the presence of railway embankment and implements them in vehicle/track interaction dynamic analyses. Considering a moving car body as multi bodies with 10 degrees of freedom and the ballasted track including rail, sleeper, ballast, subgrade and embankment, two categories of numerical analyses are performed by considering the new substructure systems including type A (initiation of stress overlap areas in adjacent sleepers from the ballast layer) or type B (initiation of stress overlap areas in adjacent sleepers from the subgrade layer). A comprehensive sensitivity analyses are performed on effective parameters such as ballast height, sleepers spacing and sleeper width. The results indicate that the stiffness of subgrade, embankment and foundation increased by increasing the ballast height. Also, by increasing the ballast height, rail and ballast vertical displacement decreased.

      • KCI등재

        Field test investigation and numerical analysis of ballasted track under moving locomotive

        Seyed-Ali Mosayebi,Jabbar Ali Zakeri,Morteza Esmaeili 대한기계학회 2016 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.30 No.3

        This paper is devoted to investigating of dynamic behavior of a ballasted railway track by field tests and numerical analyses. In this regard, at first in a field test program, two different sections in a ballasted track including concrete and wooden sleepers with good quality are selected and their dynamic vertical deflections are measured due to moving locomotive. In continuation, the numerical model of vehicle track interaction is developed and its results are verified using the measured values in the field tests and the previous research studies. Finally, using the verified model, a series of sensitivity analyses are accomplished on effecting parameters including sleeper type and track modulus. Results indicate that the dynamic behavior of the ballasted track under moving locomotive is linear with concrete sleepers while non-linear with wooden sleepers.

      • KCI등재

        Fatty Acid Composition of Tissue Cultured Breast Carcinoma and the Effect of Stearoyl-CoA Desaturase 1 Inhibition

        Fatemeh Mohammadzadeh,Gholamali Mosayebi,Vahid Montazeri,Maryam Darabi,Shabnam Fayezi,Maghsod Shaaker,Mohammad Rahmati,Behzad Baradaran,Amir Mehdizadeh,Masoud Darabi 한국유방암학회 2014 Journal of breast cancer Vol.17 No.2

        Purpose: Stearoyl-CoA desaturase 1 (SCD1) is a novel therapeutictarget in various malignancies, including breast cancer. Thepresent study was designed to investigate the effect of the pharmacologicinhibition of SCD1 on fatty acid composition in tissueexplant cultures of human breast cancer and to compare theseeffects with those in adjacent nonneoplastic breast tissue. Methods:Paired samples of tumor and adjacent noncancerous tissuewere isolated from 12 patients with infiltrating ductal breast cancer. Samples were explant cultured in vitro, exposed to the highlyselective SCD1 inhibitor CAY10566, and examined for fatty acidcomposition by gas liquid chromatography. The cytotoxic andantigrowth effects were evaluated by quantification of lactate dehydrogenaserelease and by sulforhodamine B (SRB) measurement,respectively. Results: Breast cancer tissue samples werefound to have higher levels of monounsaturated fatty acids(MUFA) (p<0.001) and arachidonic acid (20:4n-6, p<0.001) anda lower level of linoleic acid (18:2n-6, p=0.02) than the normalappearingbreast tissues. While exhibiting no evident cytotoxicity,treatment with the SCD1 inhibitor, CAY10566 (0.1-1 μM), for 48hours significantly increased 18:2n-6 levels in both the tumor andadjacent normal-appearing tissue (approximately 1.2 fold, p<0.05). However, the breast cancer tissue samples showed significantincreases in the levels of MUFA and 20:4n-6 compared tothe normal-appearing breast tissues (p<0.05). The SRB growthassay revealed a higher rate of inhibition with the SCD1 inhibitorin breast cancer tissues than in normal-appearing tissues (p<0.01, 41% vs. 29%). The SCD1 inhibitor also elevated saturatedfatty acid (1.46-fold, p=0.001) levels only in the tumor tissue explant. Conclusion: The fatty acid composition and response toSCD1 inhibition differed between the explant cultures from breastcancer and the adjacent normal-appearing tissue. Altered fattyacid composition induced by SCD1 inhibition may also, in additionto Δ9 desaturation, modulate other reactions in de novo fattyacid synthesis and lipogenesis, and subsequently affect theoverall survival and progression of breast cancer.

      • KCI등재

        Fixed-bed reactor modeling for methanol to dimethyl ether (DME) reaction over γ-Alumina using a new practical reaction rate model

        Mohammad Ghavipour,Reza Mosayebi Behbahani 한국공업화학회 2014 Journal of Industrial and Engineering Chemistry Vol.20 No.4

        Dimethyl ether (DME) synthesis reaction rate was studied over a commercial sample of γ-Alumina to investigate the accuracy of the most applicable rate models. Due to the deviation of the former proposed models especially at temperatures below 593 K, a new simple empirical rate model was proposed. Besides, previous proposed correlations for methanol dehydration equilibrium constant were examined experimentally and a new equation was developed. Subsequently, one dimensional unsteady state heterogeneous model was applied to simulate adiabatic and non-adiabatic fixed-bed reactors. Temperature profile and methanol conversion along the reactors were predicted while varying feed rate and feed temperature.

      • SCIESCOPUS

        Weighted sum Pareto optimization of a three dimensional passenger vehicle suspension model using NSGA-II for ride comfort and ride safety

        Bagheri, Mohammad Reza,Mosayebi, Masoud,Mahdian, Asghar,Keshavarzi, Ahmad 국제구조공학회 2018 Smart Structures and Systems, An International Jou Vol.22 No.4

        The present research study utilizes a multi-objective optimization method for Pareto optimization of an eight-degree of freedom full vehicle vibration model, adopting a non-dominated sorting genetic algorithm II (NSGA-II). In this research, a full set of ride comfort as well as ride safety parameters are considered as objective functions. These objective functions are divided in to two groups (ride comfort group and ride safety group) where the ones in one group are in conflict with those in the other. Also, in this research, a special optimizing technique and combinational method consisting of weighted sum method and Pareto optimization are applied to transform Pareto double-objective optimization to Pareto full-objective optimization which can simultaneously minimize all objectives. Using this technique, the full set of ride parameters of three dimensional vehicle model are minimizing simultaneously. In derived Pareto front, unique trade-off design points can selected which are non-dominated solutions of optimizing the weighted sum comfort parameters versus weighted sum safety parameters. The comparison of the obtained results with those reported in the literature, demonstrates the distinction and comprehensiveness of the results arrived in the present study.

      • KCI등재

        High speed spin coating in fabrication of Pebax 1657 based mixed matrix membrane filled with ultra-porous ZIF-8 particles for CO2/CH4 separation

        Abolfazl Jomekian,Reza Mosayebi Behbahani,Toraj Mohammadi,Ali Kargari 한국화학공학회 2017 Korean Journal of Chemical Engineering Vol.34 No.2

        Modified ultra-porous ZIF-8 particles were used to prepare novel ZIF-8/Pebax 1657 mixed matrix membranes (MMMs) on PES support for separation of CO2 from CH4 using spin coating method. TEM and SEM were used to characterize modified ZIF-8 particles. SEM was also used to investigate the morphology of synthesized MMMs. The MMMs with thinner selective layer showed higher CO2 permeability and lower CO2/CH4 selectivity in permeation tests compared to MMMs with thicker selective layer. The plasticization was recognized as the main reason for rise in CO2 permeability and drop in CO2/CH4 selectivity of thinner MMMs. The gas sorption results showed that the high permeability of CO2 in MMMs is mainly due to the high solubility of this gas in MMMs, leading to high CO2/ CH4 solubility selectivity for MMMs. The fractional free volume and void volume fraction of MMMs increased as the thickness of membrane decreased. Applying higher mixed feed pressures and permeation tests temperatures resulted in increase in CO2 permeability and decrease in CO2/CH4 selectivity. At highest testing temperature (60 oC), the CO2 permeability of synthesized MMMs with thinner selective layer remarkably increased.

      • KCI등재

        Weighted sum Pareto optimization of a three dimensional passenger vehicle suspension model using NSGA-II for ride comfort and ride safety

        Mohammad Reza Bagheri,Masoud Mosayebi,Ahmad Keshavarzi 국제구조공학회 2018 Smart Structures and Systems, An International Jou Vol.22 No.4

        The present research study utilizes a multi-objective optimization method for Pareto optimization of an eight-degree of freedom full vehicle vibration model, adopting a non-dominated sorting genetic algorithm II (NSGA-II). In this research, a full set of ride comfort as well as ride safety parameters are considered as objective functions. These objective functions are divided in to two groups (ride comfort group and ride safety group) where the ones in one group are in conflict with those in the other. Also, in this research, a special optimizing technique and combinational method consisting of weighted sum method and Pareto optimization are applied to transform Pareto double-objective optimization to Pareto full-objective optimization which can simultaneously minimize all objectives. Using this technique, the full set of ride parameters of three dimensional vehicle model are minimizing simultaneously. In derived Pareto front, unique trade-off design points can selected which are non-dominated solutions of optimizing the weighted sum comfort parameters versus weighted sum safety parameters. The comparison of the obtained results with those reported in the literature, demonstrates the distinction and comprehensiveness of the results arrived in the present study.

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