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BOUNDARIES FOR AN ALGEBRA OF BOUNDED HOLOMORPHIC FUNCTIONS
Moraes, L.A.,Grados, L.-Romero Korean Mathematical Society 2004 대한수학회지 Vol.41 No.1
Let $A_b(B_E)$ be the Banach algebra of all complex valued bounded continuous functions on the closed unit ball $B_E$ of a complex Banach space E, and holomorphic in the interior of $B_E$, endowed with the sup norm. We present some sufficient conditions for a set to be a boundary for $A_b(B_E)$ in case E belongs to a class of Banach spaces that includes the pre-dual of a Lorentz sequence space studied by Gowers in [6]. We also prove the non-existence of the Shilov boundary for $A_b(B_E)$ and give some examples of boundaries.
Moraes, Christopher,Kim, Byoung Choul,Zhu, Xiaoyue,Mills, Kristen L,Dixon, Angela R,Thouless, M D,Takayama, Shuichi Royal Society of Chemistry 2014 Lab on a chip Vol.14 No.13
<P>Culturing cells in three-dimensional (3D) environments has been shown to significantly influence cell function, and may provide a more physiologically relevant environment within which to study the behavior of specific cell types. 3D tissues typically present a topologically complex fibrous adhesive environment, which is technically challenging to replicate in a controlled manner. Micropatterning technologies have provided significant insights into cell-biomaterial interactions, and can be used to create fiber-like adhesive structures, but are typically limited to flat culture systems; the methods are difficult to apply to topologically-complex surfaces. In this work, we utilize crack formation in multilayered microfabricated materials under applied strain to rapidly generate well-controlled and topologically complex 'fiber-like' adhesive protein patterns, capable of supporting cell culture and controlling cell shape on three-dimensional patterns. We first demonstrate that the features of the generated adhesive environments such as width, spacing and topology can be controlled, and that these factors influence cell morphology. The patterning technique is then applied to examine the influence of fiber structure on the nuclear morphology and actin cytoskeletal structure of cells cultured in a nanofibrous biomaterial matrix.</P>
Parkinson Anxiety Scale: A Validation Study for the Brazilian Population
Renilson Moraes-Ferreira,Wilson Mateus Gomes da Costa Alves,Maysa Alves Rodrigues Brandao-Rangel,Odilon Abrahin,Clebson Pantoja Pimentel,Evitom Correa-Sousa,Rodolfo Paula Vieira,Erik Artur Cortinhas-A 대한파킨슨병및이상운동질환학회 2020 Journal Of Movement Disorders Vol.13 No.3
The Parkinson Anxiety Scale (PAS) was developed to measure the severity of anxiety symptoms in patients with Parkinson’s disease (PD), and it has not yet been adapted and validated in Portuguese. Thus, this study evaluated the reliability and validity of a translated and adapted version of the PAS for the Brazilian population of PD patients.
Inhibition of matrix metalloproteinases: a troubleshooting for dentin adhesion
de Moraes, Izadora Quintela Souza,do Nascimento, Ticiano Gomes,da Silva, Antonio Thomas,de Lira, Lilian Maria Santos Silva,Parolia, Abhishek,de Moraes Porto, Isabel Cristina Celerino The Korean Academy of Conservative Dentistry 2020 Restorative Dentistry & Endodontics Vol.45 No.3
Matrix metalloproteinases (MMPs) are enzymes that can degrade collagen in hybrid layer and reduce the longevity of adhesive restorations. As scientific understanding of the MMPs has advanced, useful strategies focusing on preventing these enzymes' actions by MMP inhibitors have quickly developed in many medical fields. However, in restorative dentistry, it is still not well established. This paper is an overview of the strategies to inhibit MMPs that can achieve a long-lasting material-tooth adhesion. Literature search was performed comprehensively using the electronic databases: PubMed, ScienceDirect and Scopus including articles from May 2007 to December 2019 and the main search terms were "matrix metalloproteinases", "collagen", and "dentin" and "hybrid layer". MMPs typical structure consists of several distinct domains. MMP inhibitors can be divided into 2 main groups: synthetic (synthetic-peptides, non-peptide molecules and compounds, tetracyclines, metallic ions, and others) and natural bioactive inhibitors mainly flavonoids. Selective inhibitors of MMPs promise to be the future for specific targeting of preventing dentin proteolysis. The knowledge about MMPs functionality should be considered to synthesize drugs capable to efficiently and selectively block MMPs chemical routes targeting their inactivation in order to overcome the current limitations of the therapeutic use of MMPs inhibitors, i.e., easy clinical application and long-lasting effect.
Marılia Moraes Queiroz Souza,Gustavo Ratti da Silva,Itarua Machri Cola,Aniely Oliveira Silva,Maysa Isernhagen Schaedler,Lucas Pires Guarnier,Rhanany Alan Calloi Palozi,Lorena Neris Barboza,Jacqueline 한국식품영양과학회 2020 Journal of medicinal food Vol.23 No.6
Cardiovascular disease (CVD) is the leading cause of death worldwide and among its modifiable risk factors are dyslipidemia, diabetes, and smoking. Experimental models evaluated this risk factors singly, however, there is a lack of models that agglomerate these risk factors, resembling real patients and elucidating the pathophysiology of CVD. Moreover, few studies have investigated the cardioprotective effects of Baccharis trimera, a species with lipid-lowering effects. In this study, ethanol-soluble fraction of B. trimera was characterized by liquid chromatography–mass spectrometry. Diabetes was induced by streptozotocin in Wistar rats that also received 0.5% cholesterol-enriched chow and were exposed to the smoke of nine cigarettes, 5 days/week, for 4 weeks. During the last 2 weeks, the animals were treated with vehicle (C−), B. trimera, or simvastatin plus insulin. At the end, cholesterol, triglyceride, urea, and creatinine levels; blood pressure (BP); heart rate (HR); abdominal aortic morphometry; vascular reactivity; renal and cardiac oxidative status; and histopathological changes were evaluated. The agglomerate of risk factors promoted alterations contrary to those described in the literature for the isolated risk factors. The C− group exhibited oxidative stress, increase in biochemical parameters, and thickening of the wall of the abdominal aorta. HR, systolic, diastolic, and mean BP decreased, and vascular reactivity was altered. Cardiac and renal histopathological changes were observed. Treatment with B. trimera reversed these changes and this effect may be partially attributable to lipid-lowering action and to the inhibition of free radical generation. B. trimera has cardioprotective effects in this model, with no toxicity.
The cerium peculiar valence charge in CeN
Eduardo Moraes Diniz 한국물리학회 2020 Current Applied Physics Vol.20 No.2
Rare earth nitrides are very interesting due to a well-behaved ionic radii-dependent physical observables. However, cerium nitride is different in many ways, for example, its lattice parameter does not “match” with Ce ionic radius in comparison with other rare-earth nitrides. To contribute to this issue, here I propose three models, based on very accurate classical calculations, which take into account charge transfers and/or contamination by Ce4+ ions to describe valence states in cerium nitride compounds from T = 0 K to T > 1500 K. This thermal dependence of the Ce valence charge has permitted to calculate many temperature-dependent physical observables. Such information is useful to clarify the Ce valence state in cerium nitride as well as give some estimations concerning experimental data in a very large temperature range of cerium nitride compounds.
Thiago Mello Moraes,Ariane Leite Rozza,He´lio Kushima,Claudia Helena Pellizzon,Lucia Regina Machado Rocha,Cle´lia Akiko Hiruma-Lima 한국식품영양과학회 2013 Journal of medicinal food Vol.16 No.12
Previous studies have described the gastroprotective effects of essential oils that are derived from Citrus aurantium (OEC) and its main compound d-limonene (LIM) in a model of chemically induced ulcers in rats. However, these studies do not address the compound’s healing effects on the gastric mucosa. Thus, the aim of this work was to evaluate the healing activity of OEC and LIM in acetic acid-induced gastric ulcers in rats, a model that reproduces human chronic ulcers. The obtained results demonstrated that lower effective doses of OEC (250 mg/kg) and LIM (245 mg/kg) induced gastric mucosal healing with a cure rate of 44% and 56%, respectively, compared with the control group (P < .05). During the 14 days of OEC or LIM treatment, none of the groups demonstrated toxicity in terms of body and organ weight or serum biochemical parameters. Both OEC and LIM treatment promoted an increase in epithelial healing, as confirmed by immunohistochemistry, which was greater in the animals that were treated with the positive control. In addition, both treatments increased cellular proliferation as measured by proliferating cell nuclear antigen and cyclooxygenase 2 expression in the gastric mucosa, vascular endothelial growth factor-mediated blood vessel formation in the margin of the ulcer, and production of gastric mucus, which fortifies the gastric protective barrier. We concluded that OEC and LIM, two common flavoring agents, promote gastric mucosal healing without any apparent toxic effect, resulting in better gastric epithelial organization in the treated rats.
DOES COUNTRY OF ORIGIN MATTER IN FACE OF STRONG GLOBAL BRANDS?
Sergio Garrido Moraes,Vivian Iara Strehlau,Reynaldo Dannecker Cunha 글로벌지식마케팅경영학회 2014 Global Marketing Conference Vol.2014 No.7
This paper aims to compare the impact of country of origin and brand’s aspects on young consumers’ willingness to buy global brands. We chose the United States because this country is the origin of the most valuable global brands, besides arousing contradictory opinions and feelings, as well as reactions of love and hate. The brands Apple, Levi’s and McDonald's, represent products and services, all of them recognized as global and US iconic brands, at the same time: Apple has been admired and followed; McDonald’s has been used as a symbol in political demonstrations against the United States or against globalization, while some protesters wear Levi’s jeans. The tested constructs include aspects related to country of origin (Country Image, Country Affinity, Ethnocentrism) and brand (Brand Personality and Self-Brand Connection). We conducted a survey with 367 students, potential consumers of the brands, and applied Structural Equation Modelling to analyze the impacts of constructs on their willingness to buy. The results indicate that consumer-brand relationship showed greater strength and significance than other constructs, highlighting that during purchasing it is more important how the consumer perceives himself in relation to the brand than the way he perceives or feels about brand’s country of origin. We deliberately chose brands of high brand equity for analysis, but in the future, the model could be applied to low brand equity brands, not-iconic brands, other countries and its brands, and other product categories.