Crawford Ⅲ형과 Ⅳ형 흉복부 대동맥류 4예 보고

문성민,손민수,이길연,이상목,고석환,홍성화,윤충,오수명,박호철 대한혈관외과학회 2003 Vascular Specialist International Vol.19 No.2

PTFE 이식편을 이용한 대퇴동맥과 슬관절이하 동맥 우회로술의 결과 분석

문성민,손민수,이길연,이상목,고석환,홍성화,윤충,오수명,박호철 대한혈관외과학회 2004 Vascular Specialist International Vol.20 No.1

Co-60 감마선의 조사선량 측정

하석호,김현문 대한방사선 방어학회 1991 방사선방어학회지 Vol.16 No.2

감마선 조사선량의 국가표준을 확립하기 위하여 Co-60 감마선에 대한 조사선량을 절대측정을 수행하였고 그 값이 갖는 오차한계를 분석 평가하였다. 측정기로는 고순도 흑연으로 제작된 원통형 이온전리함을 사용하였고 이온화 전류 측정은 vibrating reed 증폭기를 사용한 전하모드법에 의해 수행되었으며 관련 물리상수 및 각종 관련 보정인자를 평가하여 이온화 전류 측정값으로부터 조사선량률을 결정하였다. Measurement of Co-60 gamma rays has been made for establishment of exposure standard and analyze it's overall uncertainties. Exposure rate determined by the charge mode method using vibrating reed amplifier with cylinderical type cavity chamber. The values of a variety of physical constants and the correction factors are evaluated. The resulting exposure rate is 690.81 R/h at the distance of 1 m from the source and the related uncertainties is ±0.8%.

역 유동층 생물막에서의 기질제거 속도상수와 유효확산계수

추석렬,송승구,박문기,최윤찬,김동석 부산대학교 환경문제연구소 1994 環境硏究報 Vol.12 No.-

The substrate removal rate in a biofilm was investigated by the measurement of substrate concentration in an inverse fluidized bed operated batchwisely. When the biofilm thickness was below 60㎛, the overall reaction rate was found as first order but it turned out to zero order at the thickness of above 60㎛. The reaction rate constant and the effective diffusivity could be calculated by using a mass balance and a diffusion model in the biofilm and a typical effective diffusivity of zero and first order reaction were calculated as 5.49×??㎠/s and 2.3×??㎠/s, respectively. In the region of zero order reaction, the effect of diffusion on the effectiveness factor increased with increasing biofilm thickness. Therefore in the zero order region, the diffusion step controlled the system while the reaction step controlled in the first order region.

새로 고안한 풍선박리기를 사용한 임상경험

최문수,고경석,박상훈 大韓成形外科學會 1999 Archives of Plastic Surgery Vol.26 No.3

A new balloon dissector, a modification of a Foley catheter, was devised and it can be used either as a dissector or a tissue expander. Since most operating time was spent in balloon manipulation (inflation/deflation), the duct for saline injection was made to be wider than the Foley catheter. As a result, the balloon could be inflated faster than before. In order to reduce the scar at the donor site, harvest of the sural nerve using endoscopic technique is currently applied, but utilization of this method is technically difficult and requires a long operating time. For these reasons, new our method of using a balloon dissector was devised. The balloon dissector can also be used for immediate intraoperative tissue expansion for the reconstruction of small skin defects without distortion. We have found that the advantages of using the new balloon dissector include a reduction in operating time, preservation of the perforating vessels, and primary closure with less tension. In addition, this simple and inexpensive instrument is cost-beneficial to patients.

부대동맥 림프절 또는 쇄골상부 림프절에 국한된 전이가 있는 재발성 자궁경부암 환자들의 예후에 관한 연구

최석철,문형배 동국대학교 의학연구소 1998 東國醫學 Vol.5 No.-

자궁경부암에서 림프절 전이가 병소의 재발이나 환자의 예후에 악영향을 미친다는 것은 주지의 사실이다. 그러나 자궁경부암으로 일차치료 후에 재발한 자궁경부암 환자들 중에서 부대동맥 및/혹은 쇄골상부 림프절에 전이가 있는 환자들의 임상적 특징 및 예후에 대해서는 잘 알려져 있지 않다. 따라서 본 연구는 자궁경부암으로 근치적 전자궁적출술 및 골반림프절 절제술이나 방사선치료 후에 재발한 환자들 중 부대동맥 및/혹은 쇄골상부 림프절에 전이가 있는 환자들의 임상적 특징 및 예후에 대해 알아보고자 하였다. 1991년 1월부터 1995년 12월 까지, 원자력병원 산부인과에서 자궁경부암으로 일차치료 후 전산화 단층촬영 및 세침흡인 세포검사에서 부대동맥 및/혹은 쇄골상부 림프절전이가 증명된 재발성 자궁경부암 환자 55명을 대상으로 하였다. 1. 대상환자 55례 중 부대동맥 림프절에 국한된 전이가 있었던 경우는 31례(56.4%)였으며, 쇄골상부 림프절에 전이가 있었던 경우는 24례(43.6%)였다. 쇄골상부 림프절에 전이가 있었던 24례 중 8례는 쇄골상부 림프절에 국한된 전이가 증명된 경우(Supraclavicnlar lynph node : SCLN only군)였고, 나머지 16례는 부대동맥 림프절 및 쇄골상부 림프절에 전이가 동시에 있는 경우(both군)였다. 2. FIGO 임상병기별 분포는 Ⅰ기 9.1%, Ⅱ기 56.4%, Ⅲ기 32.7%, Ⅳ기 1.8%였다. 세포형태에 따른 림프절 전이율은 편평상피세포형이 96%(53/55)였다. 대상환자 55례 중 22례(40.0%)는 일차치료 당시 이미 골반림프절에 전이가 있었던 경우였다. 대상 환자들의 원발암 치료는 방사선 치료만을 시행 받은 경우가 60.0%(33/55), 방사선 치료와 항암화학요법을 시행 받은 경우가 18.2%(10/55), 수술 및 방사선 치료, 항암화학요법을 시행 받은 경우가 18.2%(10/55), 그리고 수술 및 방사선 치료를 시행 받은 경우가 3.6%(2/ss)였다. 3. 전체 연구대상 환자 55례의 3년 생존율은 14.4%이었으며, 부대동맥 림프절전이군과 쇄골상부 림프절전이군의 3년 생존율은 각각 15.4%, 10.7%이었고, SCLN only군 및 both군의 3년 생존율은 각각 0%, 19.7% 이었다. 결론적으로, 쇄골상부 림프절 전이가 있는 환자는 부대동맥 림프절에 국한된 전이가 있는 환자보다 3년 생존율이 낮음을 알 수 있었으며, 이에 따라 재발성 자궁경부암 환자에서는 쇄골상부 림프절의 전이 유무가 환자의 예후를 추정하는데 중요한 지표가 될 것으로 생각되었다. It is evident from previous reports that in patients with cervical cancer with metastases to lymph nodes have unfavorable outcome, there are, however, few reports have previously been made of the clinical characteristics and prognosis of patients with metastasis limited to para-aortic lymph nodes(PALN) only versus supraclavicular lymph nodes(SCLN) following primary treatment. This paper attempts to discuss the outcome of Patients with recurrent cervical cancer metastasis limited to these lymph nodes. This report is a retrospective analysis of 55 patients with recurrent cervical cancer metastasis limited to para-aortic or supraclavicular lymph nodes following radical hysterectomy or definitive radiation therapy treated at the Korea Cancer Center Hospital, from January 1991 through December 1995. The results were as follows. 1. Of the 55 patients entered, 31(56.4%) had positive nodes on para-aortic area only and 24(46.3%) had positive nodes on supraclavicular area. 8 of 24 patients had limited metastasis to SCLN only and 16 had metastatic nodes on both para-aortic and supraclavicular area. 2. The distribution of patients according to initial FIGO stage were 9.1% in stage Ⅰ, 56.4% in stage Ⅱ, 32.7% in stage Ⅲ, and 1.8% in stage Ⅳ. In 96.4%(53/55) of cases, the histologic type was a squamous cell carcinoma. 22(40.0%) of 55 patients had pelvic lymph node metastasis at the time of initial treatment. The distribution of patients by treatment modalities prior to recurrence was 60.0%(33/55) for patients treated with radiotherapy alone, 18.2%(10/55) for patients treated with combined chemotherapy and radiotherapy, and 18.2%(10/55) for patients treated with combined surgery, radiotherapy, and chemotherapy. 3. The overall 3-year survival rate for patients with positive nodes on para-aortic or supraclavicular area was 14.4%; those who had lymph nodes limited to para-aortic only achieved 15.4%; those who had lymph nodes limited to supraclavicular lymph node achieved 10.7%. Of these, those who had nodes on supraclavicular lymph node only or both supraclavicular and para-aortic lymph node achieved 0% and 19.7% 3-year survival rate, respectively. In conclusion, the outcome for patients with metastasis to supraclavicular lymph nodes was worse than for patients with metastasis to para-aortic lymph nodes only. This suggest that the presence of metastatic carcinoma on supraclavicular lymph node may be a reliable Predictor of probability of survival in such patients.

汎植物凝集素 Phaseolus vulgalis L. 의 사람 血淸에 依한 凝集阻止에 關한 硏究

愼碩根,文國鎭 고려대학교 의과대학 1980 고려대 의대 잡지 Vol.17 No.1

Agglutination inhibition effects on Phaseolus vulgalis L. (P. vulgalis) was carried out with 1,223 of human sera and various sugars to understand serological characteristics of Panphytagglutinin, P. vulgalis. And demonstrated that the agglutination activity of P. vulgalis were inhibited by some sera but not by the others, and was designated the former as P. vulgalis inhibitor (PVI) and the later as P. vulgalis non-inhibitor(PVN). Frequencies of PVI and PVN were tested on 324 sera of healthy males, 197 sera of healthy females, as well as on 702 sera of patients with various pathological conditions. There were no differences in the distribution of PVI and PVN frequencies between male and female, and among ABO blood groups. The distribution of PVI was 95% (493) and PVN was 5% (28) in 521 of normal control group. A high frequency of PVN was noted in sera of the patients with gastric ulcer (38%, Z score=2.4397) and gastric cancer (25%, Z score=2.6633). No appreciable difference was noted in the frequency of PVN and PVI among patients with Duodenal ulcer, Gastro-enteritis, Liver cirrhosis, Hepatitis, Cholecystopathy, Pneumonia, Pulmonary tuberculosis, Bronchitis, Myocardiac infarction, CVA, Hypertension, Diabetes mellitus, Leukemia and Panperitonitis

Wolff-Parkinson-White증후군의 임상상 및 전기생리학적 소견

안신기,이문형,장양수,오동진,최인석,하종원,임세중,김병옥,정남식,심원흠,조승연,김성순 대한순환기학회 1997 Korean Circulation Journal Vol.27 No.9

Salmonella enteritica serovar Enteritidis 화농성 근염 1예

양해주,정문현,이종욱,오인석 대한감염학회 1998 감염 Vol.30 No.3

Pyomyositis is an acute bacterial infection of skeletal muscle usually due to Staphylococcus aureus. Salmonella species represent an uncommon causative agent of pyomyositis which has been reported in patients with various underlying illnesses. We experienced a case of pyomyositis caused by Salmonella enteritica serovar Enteritidis in a 45-year-old diabetic man who was admitted with a two-week history of progressive pain of left knee and hip joint. Computed tomography revealed a 4.0 cm-sized ovoid abscess in the left iliacus muscle, which underwent incision and drainage. Culture obtained at operation revealed S. enteritidis. The patient was successfully managed with drainage and ciprofloxacin.

초정밀 가공기를 위한 다극자석 선형 모터와 초정밀 스테이지 설계

김기현,이문구,김동민,권대갑,조형석 한국공작기계학회 2003 한국공작기계학회 춘계학술대회논문집 Vol.2003 No.-

본 논문은 초정밀 가공기에 적용 가능한 6자유도의 운동이 가능한 초정밀 스테이지의 설계를 기술한다. 본 초정밀 스테이지는 특히, 광학을 이용한 가공기와 절삭력이 작은 가공기에 적합하다. 스테이지는 장행정·단행정 스테이지로 구성된 이중 서보를 채택한다. 장행정 스테이지는 초정밀 운동에 방해가 되는 운동을 줄이며 높은 효율을 갖는 다극 자석 배열을 이용한 선형모터를 사용한다. 그리고 단행정 스테이지는 장행정 스테이지와의 기계적 결합에 의한 구조적 영향성을 없애는 개념을 적용할 수 있는 보이스 코일 모터을 이용한다. 그리고 각 구동부는 최상의 성능을 유지할 수 있도록 최적설계를 수행한다.