영상분할통신을 이용한 화상진료시스템의 설계

김단환,정기봉,오무송 조선대학교 전자정보통신연구소 2002 電子情報通信硏究所論文誌 Vol.5 No.2

In general cases, the conventional internet connected to a terrestrial network is transmit too large medical images. To overcome this low speed transmitting rate problem of the internet, we have studied about an image division communication system as a fast telemedicine system. The Image division communication system was 5 10 times faster than the conventional terrestrial internet link. Also, we have developed a Web-based telemedicine system that can access every permitted server of hospital via the internet. Studied image division communication corrected problem of other reflex quality decline in erratic transmission of reflex by transmission speed imbalance that is problem of single communication techniques that used in existing reflex transmission. Also, could keep quality state of fixed reflex gouge abnormal transmission speed. Visual Basic and C++, ASP programming techniques were used to make our system and it can access and retrieve medical information and image through only public web browse such as internet explorer without additional specific tools. To increase the transmitting speed of our telemedicine system, JPEG method was used. In conclusion, we were able to develop a fast and public telemedicine system using the proposed image division communication system and Web technology. Image division communication system technology increased the speed of the conventional internet and Web technology extended the scope of use for telemedicine system from intrahospital to public us.

Bacillus sp. Ye-1213이 생산하는 chitinase의 동정, 분리정제 및 특성

오두환,허남윤,백무열 연세대학교 산업기술연구소 1990 논문집 Vol.22 No.1

국내 해변 연안의 해변의 토양으로부터 chitinase 활성이 우수한 균주를 분리하고 동정하여 Bacillus sp. YE-1213으로 명명하였다. Chitinase를 생산하기 위한 최적 배양조건은 1.0%(w/v, dry base) Colloidal chitin, 1.0%(w/v) Tryptone, 0.05%(w/v) MgSo₄·7H₂O, pH 8.0, 30℃, 배양시간 48시간이었다. 효소는 (NH₄)₂SO₄분별침전, affinity adsorption, Sephadex G-200 gel filtration의 과정을 거쳐 정제한 결과 비활성 81.32units/mg, 정제도 16.7배, 수율은 15.8%이었다. 정제된 효소는 최적 반응조건은 pH 6.0, 40℃ 이었으며, 온도에 대한 효소안전성은 40℃까지는 매우 안정하였고 pH에 대한 안정성은 pH 5.0-9.0에서 안정하였다. 정제된 효소의 Km 값은 1.74mg/ml이었고 PCMB, I₂, ?? ion, ?? ion 에 의해 저해되었으며 ?? ion, ?? ion 및 ?? ion 에 의해 1.21배, 1.12배, 1.18배의 효소활성이 증가하였다. A bacterium with the highest chitinase activity selected from the soil and identified as a Bacillus sp. YE-1213. The optimal condition for the production of chitinase was as follows; 1.0% (w/v, dry base) colloidal chitin, 1.0%(w/v) tryptone, 0.05%(w/v) MgSO₄·7H₂O, pH8.0, 30℃, 48 hrs. The chitinase was purified about 16.7 folds by ammonium sulfate fraction, affinity adsorption and Sephadex G-200 gel filtration. Optimal temperature and pH for the enzyme activity were 40℃ and pH 6.0. The enzyme was stable between pH 5.0-9.0 and up to 40℃. Its activity was activated by ??, ??, and ?? while inhibited by PCMB, I₂, ?? and ??.

포러스콘크리트의 기초물성에 미치는 시멘트페이스트의 유동성 및 진동다짐시간의 영향에 관한 실험적 연구

김무한,백용관,최영욱,강석표,김재환,이성일 忠南大學校 産業技術硏究所 2001 산업기술연구논문집 Vol.16 No.2

This study analyzed the influence of paste fluidity and vibration time for fundamental properties of porous concrete. Results of this study were shown as follows: 1) Even if target void ratio is same, void ratio and compressive strength of porous concrete is different according to w/c, paste flow and vibration time. So, In case of target void ratio, we must consider the influence of w/c, past flow and vibration time. 2) Though w/c and vibration time is same, as paste flow increase, all void ratio, continuous void ratio, and compressive strength decrease and difference between upper and lower void ratio increase. 3) Though w/c and paste flow is same, as vibration time increase, all void ratio and continuous void ratio decrease and difference between upper and lower void ratio increase. Also, compressive strength increase by 10 seconds and decease after 10 seconds. 4) As types of superplasticizer is different, all void ratio, continuous void ratio, and compressive strength is different. So, we must give consideration to paste fluidity and vibration time in order that increase of strength of porous concrete and distribution of uniform void.

배합조건에 따른 포러스콘크리트의 강도증진에 관한 실험적 연구

김문한,백용관,김재환,유범재 충남대학교 산업기술연구소 2000 산업기술연구논문집 Vol.15 No.1

In recent years, the study on the porous concrete which has excellent permeability is actively advanced in the field of architectural and civil engineering. But porous concrete has a reciprocal concept in the aspect of comparative large and continuos void structure and reduction of void for insurance of the necessary strength on the mixing proportion, must have satisfied of the properties of these. Therefore this study is series of experiment for the strength elevation and evaluated the effect according to adding ratio fly-ash, fine replacement ratio, cement content and coarse aggregate max size. As a result, the strength of porous concrete was elevated by an increase of adding ratio fly-ash, fine replacement cement content and a decrease coarse aggregate max size.

향류 냉각 반응기의 정상상태 모사

趙武煥 嶺南大學校 工業技術硏究所 1982 연구보고 Vol.10 No.1

Under the assumption that a first order, exothermic reaction takes place in the reactor, and reactant and coolant flow countercurrently without axial and radial dispersions of concentration and temperature in each phase. Temperature and conversion profiles of process stream, and temperature profiles of coolant are estimated numerically along the length of nonisothermal and nonadiabatic tubular reactor. The results are compared with those of isothermal and adiabatic reactors. The effects of various dimensionless parameters on the temperature and conversion profiles are discussed.

Cisplatin과 Tobramycin이 白鼠 Corti器에 미치는 영향에 關한 電子 顯微鏡的 硏究 : Ultrastructural Study

김동환,신태균,김무강,김홍선,김원식 충남대학교 의과대학 지역사회의학연구소 1989 충남의대잡지 Vol.16 No.1

In order to study the morphological changes of Corti’s organ in the rat treated with cisplatin and tobramycin, thirty-three rats, weighing between 200∼250g, were used, and divided into 4 groups, i.e., 3 rats were used for control, and 30 rats were used for 3 experimental groups. Each experimental group was divided into cisplatin-treated, tobramycin-treated, and both cisplatin and tobramycin treated group with 10 rats. Rats were injected with a single dose of 7.7㎎/㎏ of cisplatin intraperitoneally and 50㎎/㎏/day of tobramycin for 2 days intramuscularly, respectively or both. Treated rats were sacrificed on the 3rd and 5th day after the first injection. Results were as follows; 1. Cisplatin-treated group: Outer hair cells of Corti’s organ were degenerated with the formation of vacuoles and appearance of lysosomes, however, inner hair cells showed mild vacuolization. 2. Tobramycin-treated group: NO pathological changes were found in Corti’s organ. 3. Combined cisplatin and tobramycin treated group: Outer and inner hair cells showed vacuolization, appearance of lysosomes, myelin figures and multivesicular body. There were also multivesicular body in the inner phalangeal cell and myelin figure in the Reissner’s membrance. 4. Degeneration of Corti’s organ in the combined treated group was more sever than those of the single cisplatin-treated or tobramycin-treated group. 5. NO pathological differences of Corti’s organ in duration of postinjection were manifested in any groups. It can be concluded that cisplatin induces toxicity to inner ear and cisplatin enhance toxicity more in continued treated with tobramycin.

전단력 하에서 유도된 광민감군이 첨가된 HDPE 필름의 광분해

조무환,이훈복,신부영 嶺南大學校 環境問題硏究所 1995 環境硏究 Vol.15 No.1

융용 혼합기를 이용하여 공기 분위기 하에서 강한 전단력을 혼합물에 가하여 광분해성 M/B(Master Batch)를 제조하였다. 제조된 M/B가 45 중량 % 첨가된 광분해성 HEPE 얇은 필름과 분해성 M/B가 첨가되지 않은 일반 HDPE 필름을 인플레이션 법으로 제조하였다. 두 필름의 광분해성을 시험하기 위하여 필름을 자외선 조사기와 옥외에 노출시켜 기계적 물성 및 필름의 표면 변화를 살펴보았다. 자외선 조사 시험에서 분해성 필름은 120시간 이내에 처음 신도의 95%를 잃고 매우 취약한 상태로 되었으나, 비분해성 필름은 150시간 조사에도 처음 신도의 80%를 유지하고 있었다. 옥외 노출 시험에서는 분해성 필름의 경우 옥외 노출 21일 후 처음 신도의 약 98%를 상실하였으나, 비분해 필름은 같은 노출 시간에 원래 신도의 98%를 유지하고 있었다. SEM을 이용하여 필름 표면을 관찰한 결과, 특이한 표면 변화를 보여주었다. Photodegradable master batch was prepared by using mechanical oxidation during melt mixing process with high shear and in the presence of air. High density polyethylene (HDPE) thin film containing 45 wt % photodegradable M/B (Master Batch) and common high density polyethylene (HDPE) thin film were prepared by inflation film processing. The films were exposed under both mercury-vapor lamp light and sunlight. The photodegradable film lost about 95 % of its original elongation for 120 hours irradiation and was very brittle. The common film without photodegadability retained 80 % of its original elongation for 150 hours irradiation. Under sunlight, photodegradable HDPE film lost about 98 % of its original elongation at break after 21 days exposure and was very brittle. The common film still retained 88 % of its original elongation at the same period. Surface morphology of the films was examined by using scanning electron microscopy (SEM). SEM micrographs revealed the interesting change of the surface morphology of photodegradable thin film during outdoor exposure.

Baculovirus Vector System에 의해 발현된 재조합 Pseudorabies Virus Major Capsid Protein의 면역원성

전무형,안동준,장경수,조용성,박종현,송재영,현방훈,안수환 충남대학교 생물공학연구소 1997 생물공학연구지 Vol.5 No.-

The recombinant pseudorabies virus major capsid protein (rMCP) was produced by expression of the MCP gene in Sf-9 cell using baculovirus transfer vector system. Following evaluation of the immunochemical properties of the rMCP, the immunogenicity of the recombinant subunit protiens were investigated in guinea pig and swine to obtain the preliminary guide line for the subunit vaccine using rMCP and gP50. It was proved that ultrasonication and 30% ammonium sulfate was most efficient to concentrate and purify the protein. The rMCP was safe in mice, guinea pigs and piglets. In guinea pigs, rMCP mixed with various adjuvants induced substantial degree of serum neutralizing antibody titers, but revealed incomplete protecivity against challenge. In swine, the combination of rMCP and gP50 showed the higher serum neutralizing antibody titers and cellular immune responses than rMCP alone. However, the protectivity was lower in comparison with the commercial gI-deleted inactivated vaccine. We expect these results to contribute to characterization of MCP gene of Korean isolate of PRV and to ultilize as preliminary information for prodution and evaluation of PRV recombinant subunit vaccines.

PVA-ECC를 활용한 Half PC 복합체의 역학적 특성에 관한 실험적 연구

김재환,김영덕,김갑수,조봉석,장종호,김무한 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

ECC represents one particular class of HPFRCC, which are defined by an ultimate strength higher than their first cracking strength and the formation of multiple cracking during the inelastic deformation process. This study is to provide the fundamental data for the development of hybrid construction method such as the half PC(Precast concrete) reinforced by PVA-ECC, the mechanical properties of half PC according to the alteration of properties of PVA-ECC in terms of the type of fiber, Vr, S/M, placing height of PVA-ECC, are experimentally investigated. As the results. it is found that the half PCs of PVA-ECC have very higher mechanical performance in terms of yield load, strain capacity beyond yield point and maximum flexural load than that of mortar. Also, flexural crack in the half PCs of PVA-ECC are not localized at first crack and are growed to many micro crack, especially multiple cracking in specimen of P(12)-30-0.1ㆍ3 occurred.

企業倫理와 倫理綱領의 實踐方案에 관한 硏究

裵武煥 관동대학교 기업경영연구소 1998 경영논집 Vol.17 No.-