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Chemical Composition and Biological Activities of Calamintha officinalis Moench Essential Oil
Maria Teresa Monforte,Olga Tzakou,Antonia Nostro,Vincenzo Zimbalatti,Enza Maria Galati 한국식품영양과학회 2011 Journal of medicinal food Vol.14 No.3
Calamintha officinalis Moench essential oil is used in cooking as an aromatic herb and also to improve the flavor and fragrance of several pharmaceutical products. The essential oil, obtained by hydrodistillation (5mL=kg), was analyzed by gas chromatography–mass spectrometry and gas chromatography–flame ionization detection. Sixty-four components were identified,constituting 99.7% of the total oil. The major component was found to be carvone (38.7%), followed by neo-dihydrocarveol (9.9%), dihydrocarveol acetate (7.6%), dihydrocarveol (6.9%), 1,8 cineole (6.4%), cis-carvyl acetate (6.1%), and pulegone (4.1%). The essential oil showed antifungal and antimicrobial activity against Gram-positive bacteria. In addition, it presented a very low toxicity both in vivo (50%lethal dose>100mg=kg) and in vitro in the Artemia salina test (50%lethal concentration>500 uL=mL). C. officinalis essential oil, in rodents, produces the typical effects in behavior of a nonselective central nervous system-depressant drug; it potentiates the hypnotic effects of sodium pentobarbital, decreasing the induction time and enhancing the sleeping time. Moreover, it produces a decrease in body temperature and a protection against pentylenetetrazole-induced convulsions.
Maria T. Monforte,Vincenzo Fimiani,Francesco Lanuzza,Clara Naccari,Salvatore Restuccia,Enza M. Galati 한국식품영양과학회 2014 Journal of medicinal food Vol.17 No.4
Feijoa sellowiana Berg var. coolidge fruit juice was studied in vivo for the anti-inflammatory activity by carrageenin-induced paw edema test and in vitro for the effects on superoxide anion release from neutrophils in human whole blood. The fruit juice was analyzed by the high-performance liquid chromatography method, and quercetin, ellagic acid, catechin, rutin, eriodictyol, gallic acid, pyrocatechol, syringic acid, and eriocitrin were identified. The results showed a significant anti-inflammatory activity of F. sellowiana fruit juice, sustained also by an effective antioxidant activity observed in preliminary studies on 1,1-diphenyl-2-picrylhydrazyl (DPPH) test. In particular, the anti-inflammatory activity edema inhibition is significant since the first hour (44.11%) and persists until the fifth hour (44.12%) of the treatment. The effect on superoxide anion release was studied in human whole blood, in the presence of activators affecting neutrophils by different mechanisms. The juice showed an inhibiting response on neutrophils basal activity in all experimental conditions. In stimulated neutrophils, the higher inhibition of superoxide anion generation was observed at concentration of 10 - 4 and 10 - 2 mg/mL in whole blood stimulate with phorbol-myristate-13-acetate (PMA; 20% and 40%) and with N-formyl-methionyl-leucyl-phenylalanine (FMLP; 15% and 48%). The significant reduction of edema and the inhibition of O2- production, occurring mainly through interaction with protein-kinase C pathway, confirm the antiinflammatory effect of F. sellowiana fruit juice.
Influence of calcite content on fluorine compound emissions during ceramic tile firing
J. Garcia-Ten,E. Monfort,P. Gomez,S. Gomar 한양대학교 세라믹연구소 2006 Journal of Ceramic Processing Research Vol.7 No.1
The manufacture of traditional ceramic products (ceramic tiles, roof tiles and bricks) is often associated with the emission of fluorine compounds during the firing stage. According to the literature such emissions can be reduced by adding CaCO3 to the raw materials mixture used in fabricating these products. However, data available to the authors indicate that this procedure, which has been successfully applied in manufacturing structural ceramics (roof tiles and bricks), is ineffective in ceramic tile manufacture. The present study has sought to establish why the CaCO3 addition fails to reduce fluorine compound emissions during the ceramic tile firing stage. The study has thus determined the influence of CaCO3 content on the evolution of the crystalline phases with firing temperature in a typical floor tile composition to which additions of CaF2 were made; additions of BaF2 and SrF2 were also made to this floor tile body, and the thermal stability of these three fluoride compounds was studied. The study shows that the effectiveness of CaCO3 in reducing fluorine compound emissions in roof tile and brick manufacture is due to the relatively low firing temperature (850-1000 °C) involved, which enables part of the CaF2 to be retained in the pieces, and to the formation of cuspidine, which is stable up to 1050 °C. At higher temperatures (ceramic tiles are typically fired at temperatures of 1100-1200 °C), the fluorine-containing crystalline species (fluorite and cuspidine) are unstable, causing fluorine compound emissions to rise.
Ovarian Stromal Hyperplasia: A Rare Cause of Postmenopausal Hyperandrogenism
Teresa Lozoya Araque,Isauro Rogelio Monfort Ortiz,José Enrique Martín González,Alenda Jiménez García,Inmaculada Navarro Hidalgo,Verónica Andrade Gamarra,Cecilia Parrell Soler,Fernando Gil Raga 대한폐경학회 2020 대한폐경학회지 Vol.26 No.1
Ovarian hyperthecosis and ovarian stromal hyperplasia (OSH) are two uncommon non-neoplastic causes of ovarian hyperandrogenism, whose etiology is still unknown. These conditions are characterized by obesity, hyperinsulinemia, acanthosis nigricans, and even virilization, mainly in postmenopausal women. Here we have reported the case of a 67-year-old patient with a diagnosis of OSH, which was resolved after bilateral laparoscopic oophorectomy. In this case report, we have discussed two different conditions posing a diagnostic challenge and requiring a high index of suspicion.