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Mizuki, Daisuke,Mizuki, Mayuko,Nakano, Hajime,Hanada, Katsumi Korean Society of Photoscience 2002 Journal of Photosciences Vol.9 No.2
Photodynamic therapy using topical 5-ALA has been used for non-melanoma skin cancers. Recently, the therapeutic method using incoherent light brought beneficial result in the treatment for mycosis fungoides. We used ALA-PDT for two Japanese patients suffering from lymphadenosis benigna cutis. In both cases, lesions were markedly faded and histologically, the number of infiltrated cells also decreased. We suggest that ALA-PDT can be used as an effective and safe modality in the treatment of benign cutaneous lymphoma.
Mizuki Kitayama,Duyen T.P. Nguyen,Na Lu,Michiko Takagaki 한국원예학회 2019 원예과학기술지 Vol.37 No.2
Light quality is a critical factor that affects plant quality, including phytochemical accumulationand marketable characteristics, in closed-type plant production systems. The purpose of this studywas to determine the appropriate light quality for production of good quality water spinach in termsof its appearance and accumulation of phytochemicals in an artificial environment. Plants werehydroponically cultured under five different light quality conditions: red, blue, green, red and blue(as a control), and red and blue with far red at a photosynthetic photon flux density of 200 μmol·m-2·s-1for 14 days after transplantation. Shoot (stem and leaf) fresh weights (FW) under red-containinglight conditions increased more than 39.7% compared to that under monochromatic blue light, andmonochromatic red light produced significantly higher stem FW but lower leaf FW compared tothat under blue-containing light conditions. Monochromatic blue light significantly increased theantioxidant activity capacity in leaves and stems more than 210.0% compared to other treatments. However, blue-containing light significantly stimulated physiological disorder (intumescence injury)in stems and suppressed stem elongation compared to monochromatic red or green light. Monochromaticred light reduced the number of intumescent lesions by 95.8% and enhanced stem elongationcompared to control. These findings suggest that red-rich light promotes growth of water spinachwith less intumescence.
Synthesis and photoluminescence properties of HEu(MoO4)2 nanophosphor
Mizuki Watanabe,Kazuyoshi Uematsu,김선욱,Kenji Toda,Mineo Sato 한양대학교 세라믹연구소 2014 Journal of Ceramic Processing Research Vol.15 No.3
The HEu(MoO4)2 nanophosphor was synthesized for the first time by the H+ -exchange of KEu(MoO4)2. The nanophosphor obtained in the present study maintain the triclinic KEu(MoO4)2 type structure in a single phase form with high crystallinity. The HEu(MoO4)2 phosphor has rod-like particle morphology (length 0.5-20 µm, diameter 50-400 nm). Both HEu(MoO4)2 powder and solution shows red emission due to the 4f-4f transition of Eu3+.
Unilateral loss of thoracic motion after blunt trauma: a sign of acute Brown-Séquard syndrome
Mizuki Sato,Akira Kuriyama,Ryo Ohtomo 대한응급의학회 2019 Clinical and Experimental Emergency Medicine Vol.6 No.3
Late-onset Brown-Séquard syndrome (BSS) is a rare condition resulting from a spinal cord injury that develops weeks to years after a blunt trauma. Acute-onset BSS after a blunt injury has been rarely reported. Here, we report on a case of BSS, in a 58-year-old man, that developed immediately after a motor vehicle accident. Upon admission, loss of right thoracic motion, complete right paresis, and loss of pain and temperature sensations below the C3 level on the left side were observed. Magnetic resonance imaging showed hyperintensities within the cervical spinal cord at the C2–C3 level, confirming the diagnosis of BSS. Thoracic motion rapidly recovered, but other neurological sequelae persisted. BSS related to cervical cord injury should be suspected when patients develop hemiparesis and contralateral sensory loss immediately after a blunt trauma. Likewise, clinicians should be aware that unilateral loss of thoracic motion could be an important sign of BSS.
Rehabilitation Support Robot for Self-Standing-Up Training of Hemiplegic Stroke Patients
Mizuki Kitamura,Lin Han,Takahito Yamaji,Shunya Kaneko,Yoshifumi Morita,Hirofumi Tanabe 제어로봇시스템학회 2016 제어로봇시스템학회 국제학술대회 논문집 Vol.2016 No.10
The final goal of our research is to develop a rehabilitation support robot for self-standing-up training of hemiplegic stroke patients to restore normal standing-up motion. To improve the motor function of the patient’s paralyzed leg, a guided standing-up training is effective. The therapist controls the patient’s left/right load balance by pulling or pushing the patient’s waist during standing-up training. The purpose of this study was to clarify the patient’s waist movement guided by the therapist during the guided standing-up motion. For this purpose, we investigated the relationship between the patient’s waist movement and the left/right load balance during guided standing-up motion. From the analysis results, we found the ideal pattern of load balance ratio during guided standing-up training. Moreover, we found that the patient’s waist movement corresponded to the ideal pattern of load balance ratio. This movement trajectory is expected to be useful in designing a controller of a rehabilitation support robot.
Clinical Response to Valproate in Patients with Migraine
Mizuki Ichikawa,Hirotaka Katoh,Tatsuya Kurihara,Masakazu Ishii 대한신경과학회 2016 Journal of Clinical Neurology Vol.12 No.4
Background and Purpose Valproate is used as a prophylactic drug for migraine, but it is not be effective in all patients. We used medical records to investigate which clinical factors affected the response to valproate in patients with migraine as an original headache, and estab-lished a scoring system for predicting the clinical response to prophylactic therapy. Methods We investigated clinical factors from the medical records of 95 consistent respond¬ers (CRs) and 24 inconsistent responders (IRs) to valproate. Results Multivariate stepwise logistic regression analysis revealed that a history of hyperlip¬idemia and hay fever and the complication of depression or other psychiatric disorder were significant factors that independently contributed to a negative response, with odds ratios of 6.024 [no vs. yes; 95% confidence interval (CI)=1.616–22.222], 2.825 (no vs. yes; 95% CI= 1.046–7.634), and 2.825 (no vs. yes; 95% CI=1.052–7.576), respectively. A predictive index (PI) of the clinical response to valproate in patients with migraine was calculated using the regres¬sion coefficients of these three factors as an integer, and the index was significantly higher for IRs than for CRs (1.46±1.10 vs. 0.69±0.74, mean±SD, p<0.001). Conclusions The obtained PI may represent an appropriate scoring system for predicting the responses in these patients.